The network for 'egg activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

egg activation

The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.

NameDescriptionProbabilityFunc Analog Organism
pluplutonium0.999
gnugiant nuclei0.786
Vm26AbVitelline membrane 26Ab0.746
pngpan gu0.637
swaswallow0.278
fs(1)Yafemale sterile (1) Young arrest0.271
CG7239CG7239 gene product from transcript CG7239-RA0.265
fs(1)M3female sterile (1) M30.259
Cp36Chorion protein 360.171
CG11695CG11695 gene product from transcript CG11695-RB0.139
CG31388CG31388 gene product from transcript CG31388-RA0.138
gammaTub37Cgamma-Tubulin at 37C0.135
Vm26AaVitelline membrane 26Aa0.130
CycJCyclin J0.128
graugrauzone0.115
FemcoatCG15573 gene product from transcript CG15573-RB0.112
Yp2Yolk protein 20.097
OpbpOptix-binding protein0.087
CG6654CG6654 gene product from transcript CG6654-RA0.081
CG3294CG3294 gene product from transcript CG3294-RB0.074
AxsAbnormal X segregation0.073
CG2889CG2889 gene product from transcript CG2889-RA0.064
CG7386CG7386 gene product from transcript CG7386-RA0.059
scedscrambled0.054
c(3)Gcrossover suppressor on 3 of Gowen0.054
CG8319CG8319 gene product from transcript CG8319-RA0.051
exuexuperantia0.051
dhddeadhead0.048
CG3457CG3457 gene product from transcript CG3457-RA0.046
D19BCG10270 gene product from transcript CG10270-RA0.045
Akt1CG4006 gene product from transcript CG4006-RA0.038
CG12398CG12398 gene product from transcript CG12398-RA0.038
BzdBuzidau0.037
SnpSnipper0.031
CG6800CG6800 gene product from transcript CG6800-RA0.026
CG8366CG8366 gene product from transcript CG8366-RA0.026
CG14216CG14216 gene product from transcript CG14216-RA0.026
CG4622CG4622 gene product from transcript CG4622-RC0.025
nufnuclear fallout0.025
CG13998CG13998 gene product from transcript CG13998-RA0.024
CG13992CG13992 gene product from transcript CG13992-RB0.024
Rab2Rab-protein 20.024
Brd8CG14514 gene product from transcript CG14514-RA0.023
CG17806CG17806 gene product from transcript CG17806-RA0.023
ncdnon-claret disjunctional0.023
CG10274CG10274 gene product from transcript CG10274-RA0.021
Vm34CaVitelline membrane 34Ca0.021
atmsantimeros0.021
Cp15Chorion protein 150.021
CG6276CG6276 gene product from transcript CG6276-RA0.020
CG11350CG11350 gene product from transcript CG11350-RB0.019
CG11674CG11674 gene product from transcript CG11674-RA0.019
CG14667CG14667 gene product from transcript CG14667-RA0.019
wdbwiderborst0.018
CG17328CG17328 gene product from transcript CG17328-RA0.018
Cp16Chorion protein 160.017
CG5568CG5568 gene product from transcript CG5568-RA0.017
Fcp3CFollicle cell protein 3C0.017
CG13367CG13367 gene product from transcript CG13367-RA0.017
mei-S332meiotic from via Salaria 3320.017
SmrSmrter0.017
CG17230CG17230 gene product from transcript CG17230-RA0.017
snksnake0.017
c(2)Mcrossover suppressor on 2 of Manheim0.016
CG4820CG4820 gene product from transcript CG4820-RB0.016
mei-W68meiotic W680.016
CG4325CG4325 gene product from transcript CG4325-RA0.015
CG11696CG11696 gene product from transcript CG11696-RA0.015
CG32810CG32810 gene product from transcript CG32810-RB0.015
az2CG1605 gene product from transcript CG1605-RA0.015
oa2octopamine receptor 20.015
CG11504CG11504 gene product from transcript CG11504-RB0.014
CG17002CG17002 gene product from transcript CG17002-RB0.014
CG3225CG3225 gene product from transcript CG3225-RA0.013
wntDwnt inhibitor of Dorsal0.013
Muc4BMucin 4B0.013
CG12219CG12219 gene product from transcript CG12219-RA0.013
CG12026CG12026 gene product from transcript CG12026-RB0.013
UbqnUbiquilin0.012
CG18745CG18745 gene product from transcript CG18745-RA0.012
CG15861CG15861 gene product from transcript CG15861-RA0.012
unc-13-4ACG32381 gene product from transcript CG32381-RB0.012
CG8001CG8001 gene product from transcript CG8001-RA0.012
CG6695CG6695 gene product from transcript CG6695-RA0.012
SF1Splicing factor 10.012
CG13299CG13299 gene product from transcript CG13299-RA0.012
omdoocyte maintenance defects0.012
Xe7CG2179 gene product from transcript CG2179-RA0.011
Tsp74FTetraspanin 74F0.011
mus312mutagen-sensitive 3120.011
CG17361CG17361 gene product from transcript CG17361-RA0.011
gclgerm cell-less0.011
eloFelongase F0.011
CG11381CG11381 gene product from transcript CG11381-RA0.011
nodno distributive disjunction0.011
Cp7FbChorion protein b at 7F0.011
CG42600CG42600 gene product from transcript CG42600-RC0.011
Vm32EVitelline membrane 32E0.011
CG10147CG10147 gene product from transcript CG10147-RA0.011
CG42726CG42726 gene product from transcript CG42726-RA0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
rtcd1RNA terminal phosphate cyclase domain 10.114
nr2f6anuclear receptor subfamily 2, group F, member 6a0.042
zgc:64040zgc:640400.037
esyt3extended synaptotagmin-like protein 30.032
zgc:158604zgc:1586040.031
slc43a1asolute carrier family 43, member 1a0.030
si:dkey-222f8.3si:dkey-222f8.30.017
zgc:91835zgc:918350.016
zgc:92480zgc:924800.016
arhgdiaRho GDP dissociation inhibitor (GDI) alpha0.015
im:7163548im:71635480.015
acvr1lactivin A receptor, type I like0.014
ndrg3bN-myc downstream regulated family member 3b0.014
cpecarboxypeptidase E0.014
zgc:110788zgc:1107880.014
mgllmonoglyceride lipase0.013
mon1aMON1 homolog A (yeast)0.012
arpc5aactin related protein 2/3 complex, subunit 5A0.012
yap1Yes-associated protein 10.012
ulk2unc-51-like kinase 2 (C. elegans)0.012
rgs7regulator of G-protein signalling 70.012
ubinataxin-1 ubiquitin-like interacting protein0.011
snx6sorting nexin 60.011
sept2septin 20.011
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.011
scamp2secretory carrier membrane protein 20.011
si:ch211-198a12.6si:ch211-198a12.60.011
cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.010
alcambactivated leukocyte cell adhesion molecule b0.010
ftr83finTRIM family, member 830.010
rac1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.010
zgc:77836zgc:778360.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.531
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.296
Ptpn11protein tyrosine phosphatase, non-receptor type 110.061
Jag1jagged 10.059
Adam15a disintegrin and metallopeptidase domain 15 (metargidin)0.051
Adam12a disintegrin and metallopeptidase domain 12 (meltrin alpha)0.045
Tgfb2transforming growth factor, beta 20.045
Raver2ribonucleoprotein, PTB-binding 20.043
Hey2hairy/enhancer-of-split related with YRPW motif 20.039
Dlg4discs, large homolog 4 (Drosophila)0.038
Klf3Kruppel-like factor 3 (basic)0.036
Efnb2ephrin B20.034
Mtap2microtubule-associated protein 20.034
Fliiflightless I homolog (Drosophila)0.027
Plcg1phospholipase C, gamma 10.025
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.024
Ntf3neurotrophin 30.020
Dnm1dynamin 10.019
Hbegfheparin-binding EGF-like growth factor0.018
Cxcr7chemokine (C-X-C motif) receptor 70.018
Gata4GATA binding protein 40.017
Homer1homer homolog 1 (Drosophila)0.016
Sos1son of sevenless homolog 1 (Drosophila)0.014
Prkccprotein kinase C, gamma0.013
Dlg2discs, large homolog 2 (Drosophila)0.012
Foxc2forkhead box C20.012
Efna1ephrin A10.012
Nf1neurofibromatosis 10.012
Vegfavascular endothelial growth factor A0.010
Raver1ribonucleoprotein, PTB-binding 10.010
Shank2SH3/ankyrin domain gene 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism