The network for 'spinal cord development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

spinal cord development

The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.

NameDescriptionProbabilityFunc Analog Organism
HGTXCG13475 gene product from transcript CG13475-RB0.743
cicubitus interruptus0.713
Su(H)Suppressor of Hairless0.588
nkdnaked cuticle0.460
HLHm7E(spl) region transcript m70.432
Sema-1aCG18405 gene product from transcript CG18405-RD0.287
lblladybird late0.264
slp2sloppy paired 20.244
E(spl)Enhancer of split0.219
eveeven skipped0.216
lbeladybird early0.212
elavembryonic lethal abnormal vision0.206
emsempty spiracles0.202
HLHmbetaE(spl) region transcript mbeta0.197
par-1CG8201 gene product from transcript CG8201-RA0.172
HLHmgammaE(spl) region transcript mgamma0.171
Tao-1CG14217 gene product from transcript CG14217-RF0.170
slp1sloppy paired 10.165
HLHm5E(spl) region transcript m50.156
spensplit ends0.150
amosabsent MD neurons and olfactory sensilla0.139
snostrawberry notch0.126
NotumCG13076 gene product from transcript CG13076-RB0.125
gcmglial cells missing0.122
unc-5CG8166 gene product from transcript CG8166-RA0.112
EgfrEpidermal growth factor receptor0.106
Trim9CG31721 gene product from transcript CG31721-RB0.095
Hr46Hormone receptor-like in 460.095
Wnt2Wnt oncogene analog 20.094
beat-Iabeaten path Ia0.094
Adf1Adh transcription factor 10.092
EcREcdysone receptor0.089
Abd-BAbdominal B0.089
Ptp69DProtein tyrosine phosphatase 69D0.087
PoxnPox neuro0.082
opaodd paired0.080
nompCno mechanoreceptor potential C0.073
TolloCG6890 gene product from transcript CG6890-RA0.072
towtarget of wingless0.071
vndventral nervous system defective0.071
TrpA1Transient receptor potential A10.069
rapretina aberrant in pattern0.069
CG42629CG42629 gene product from transcript CG42629-RB0.069
m2E(spl) region transcript m20.065
HLHm3E(spl) region transcript m30.063
dallydivision abnormally delayed0.062
Ten-mTenascin major0.062
AP-2CG7807 gene product from transcript CG7807-RB0.061
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.984
tbx2bT-box 2b0.966
dccdeleted in colorectal carcinoma0.937
fgf3fibroblast growth factor 30.935
olig2oligodendrocyte lineage transcription factor 20.919
foxa1forkhead box A10.893
gli1GLI-Kruppel family member 10.885
pcdh18bprotocadherin 18b0.883
fezf2FEZ family zinc finger 20.856
dbx1adeveloping brain homeobox 1a0.850
ntlano tail a0.831
sox10SRY-box containing gene 100.817
meis3myeloid ecotropic viral integration site 30.789
gli2aGLI-Kruppel family member GLI2a0.781
shhasonic hedgehog a0.735
tbx20T-box 200.731
rereaarginine-glutamic acid dipeptide (RE) repeats a0.723
hoxb1ahomeo box B1a0.695
fgf10afibroblast growth factor 10a0.686
lhx2bLIM homeobox 2b0.676
ndr2nodal-related 20.669
flhfloating head0.629
pitx2paired-like homeodomain transcription factor 20.626
otpborthopedia homolog b0.606
lef1lymphocyte enhancer binding factor 10.589
rx3retinal homeobox gene 30.572
foxd3forkhead box D30.572
evx1even-skipped homeobox 10.546
pcdh18aprotocadherin 18a0.541
dab1bdisabled homolog 1b (Drosophila)0.520
wnt3awingless-type MMTV integration site family, member 3A0.513
otx2orthodenticle homolog 20.485
nkx2.2bNK2 transcription factor related 2b0.478
otpaorthopedia homolog a0.474
fstafollistatin a0.473
wnt5bwingless-type MMTV integration site family, member 5b0.472
foxa2forkhead box A20.459
sulf1sulfatase 10.457
lhx5LIM homeobox 50.429
neurog1neurogenin 10.421
six3bsine oculis homeobox homolog 3b0.416
prdm14PR domain containing 140.389
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.389
eomesaeomesodermin homolog a0.381
lhx1aLIM homeobox 1a0.378
ascl1aachaete-scute complex-like 1a (Drosophila)0.372
hoxa2bhomeo box A2b0.355
phox2apaired-like homeobox 2a0.349
zic6zic family member 60.336
oprd1bopioid receptor, delta 1b0.334
pax2apaired box gene 2a0.330
fzd8bfrizzled homolog 8b0.325
nkx2.2aNK2 transcription factor related 2a0.323
hlxb9lbhomeo box HB9 like b0.319
map2k4amitogen-activated protein kinase kinase 4a0.312
her5hairy-related 50.311
cdh5cadherin 50.303
nr2e1nuclear receptor subfamily 2, group E, member 10.290
nos2bnitric oxide synthase 2b, inducible0.288
znf503zinc finger protein 5030.285
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.282
nkx2.1bNK2 homeobox 1b0.282
fn1fibronectin 10.271
wnt8bwingless-type MMTV integration site family, member 8b0.264
hoxd11ahomeo box D11a0.263
etv2ets variant gene 20.261
six3asine oculis homeobox homolog 3a0.260
nkx6.1NK6 transcription factor related, locus 1 (Drosophila)0.259
ascl1bachaete-scute complex-like 1b (Drosophila)0.256
hlxb9lahomeo box HB9 like a0.249
dkk1bdickkopf 1b0.249
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.247
lmo4aLIM domain only 4a0.241
tbx5aT-box 5a0.237
foxp2forkhead box P20.235
olig3oligodendrocyte transcription factor 30.231
nf1aneurofibromin 1a0.228
hand2heart and neural crest derivatives expressed transcript 20.221
eya1eyes absent homolog 10.216
pax8paired box gene 80.213
pcdh19protocadherin 190.212
sox1aSRY-box containing gene 1a0.212
tal2T-cell acute lymphocytic leukemia 20.210
ihhaIndian hedgehog homolog a0.209
tal1T-cell acute lymphocytic leukemia 10.206
hoxb5ahomeo box B5a0.204
olig4oligodendrocyte transcription factor 40.202
dab1adisabled homolog 1a (Drosophila)0.197
notch1anotch homolog 1a0.197
zic4zic family member 40.195
tcf7l1btranscription factor 7-like 1b (T-cell specific, HMG-box)0.194
robo3roundabout homolog 30.192
dlx2bdistal-less homeobox gene 2b0.191
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
NOTCH1notch 11.000
NOTCH3notch 31.000
TAL1T-cell acute lymphocytic leukemia 10.999
JAG1jagged 10.999
DLG4discs, large homolog 4 (Drosophila)0.994
SUFUsuppressor of fused homolog (Drosophila)0.990
GLI1GLI family zinc finger 10.974
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.967
PKD1polycystic kidney disease 1 (autosomal dominant)0.955
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.950
HSPB8heat shock 22kDa protein 80.938
XIAPX-linked inhibitor of apoptosis0.929
MEOX2mesenchyme homeobox 20.907
PKD2polycystic kidney disease 2 (autosomal dominant)0.885
ATN1atrophin 10.879
SOX10SRY (sex determining region Y)-box 100.849
VAC14Vac14 homolog (S. cerevisiae)0.821
STK36serine/threonine kinase 360.815
GATA2GATA binding protein 20.784
NOTCH2notch 20.773
JAG2jagged 20.773
RCN3reticulocalbin 3, EF-hand calcium binding domain0.772
SMAD3SMAD family member 30.764
BHLHE23basic helix-loop-helix family, member e230.763
RUNX1runt-related transcription factor 10.754
HOXD12homeobox D120.738
FGF3fibroblast growth factor 30.736
LLGL1lethal giant larvae homolog 1 (Drosophila)0.734
POU3F2POU class 3 homeobox 20.707
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.701
GRB10growth factor receptor-bound protein 100.696
CPEcarboxypeptidase E0.687
CBX8chromobox homolog 80.662
RUNX1T1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.660
GRIN2Cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.651
PRKCZprotein kinase C, zeta0.643
LTBP4latent transforming growth factor beta binding protein 40.636
LBX1ladybird homeobox 10.631
PEX26peroxisomal biogenesis factor 260.626
RAXretina and anterior neural fold homeobox0.617
SKIv-ski sarcoma viral oncogene homolog (avian)0.581
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.570
BMI1BMI1 polycomb ring finger oncogene0.546
TRPC1transient receptor potential cation channel, subfamily C, member 10.544
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.541
GFI1Bgrowth factor independent 1B transcription repressor0.534
BMP7bone morphogenetic protein 70.529
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.526
FEVFEV (ETS oncogene family)0.523
LDB1LIM domain binding 10.506
TP73tumor protein p730.498
MID1IP1MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))0.491
PSAT1phosphoserine aminotransferase 10.490
TCF4transcription factor 40.482
PDX1pancreatic and duodenal homeobox 10.471
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.471
MYOD1myogenic differentiation 10.461
TCF12transcription factor 120.460
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.460
MAML1mastermind-like 1 (Drosophila)0.456
HOXD9homeobox D90.450
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.427
INSRinsulin receptor0.424
OTPorthopedia homeobox0.421
FEZ1fasciculation and elongation protein zeta 1 (zygin I)0.409
POU3F1POU class 3 homeobox 10.407
DLL1delta-like 1 (Drosophila)0.407
WNT10Awingless-type MMTV integration site family, member 10A0.387
KRTAP4-12keratin associated protein 4-120.385
TUBB2Btubulin, beta 2B0.370
MARCKSL1MARCKS-like 10.367
GATA1GATA binding protein 1 (globin transcription factor 1)0.366
LMX1ALIM homeobox transcription factor 1, alpha0.360
PYYpeptide YY0.356
SEC24DSEC24 family, member D (S. cerevisiae)0.354
QPRTquinolinate phosphoribosyltransferase0.351
SIX3SIX homeobox 30.347
BMP1bone morphogenetic protein 10.346
C1QL1complement component 1, q subcomponent-like 10.345
FOXL1forkhead box L10.343
ALX3ALX homeobox 30.338
LPHN1latrophilin 10.338
ZNF764zinc finger protein 7640.333
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.329
USP11ubiquitin specific peptidase 110.322
FOXD3forkhead box D30.320
HOXC8homeobox C80.312
VHLvon Hippel-Lindau tumor suppressor0.309
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.305
WNT1wingless-type MMTV integration site family, member 10.293
ALX4ALX homeobox 40.283
HOXD11homeobox D110.281
LHX5LIM homeobox 50.274
FZD8frizzled homolog 8 (Drosophila)0.270
ISL1ISL LIM homeobox 10.267
HOXC6homeobox C60.262
SOX11SRY (sex determining region Y)-box 110.252
WNT6wingless-type MMTV integration site family, member 60.252
LMO1LIM domain only 1 (rhombotin 1)0.251
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Otx2orthodenticle homolog 2 (Drosophila)1.000
Pitx2paired-like homeodomain transcription factor 21.000
Shhsonic hedgehog1.000
Gli3GLI-Kruppel family member GLI31.000
Fgfr2fibroblast growth factor receptor 20.999
Gli2GLI-Kruppel family member GLI20.999
Ascl1achaete-scute complex homolog 1 (Drosophila)0.999
Pax6paired box gene 60.999
Pax3paired box gene 30.999
Isl1ISL1 transcription factor, LIM/homeodomain0.998
Pax2paired box gene 20.996
Sox2SRY-box containing gene 20.996
Tbx3T-box 30.996
Hand2heart and neural crest derivatives expressed transcript 20.996
Hoxb6homeobox B60.995
Tcfap2atranscription factor AP-2, alpha0.995
Dab1disabled homolog 1 (Drosophila)0.994
Foxc1forkhead box C10.993
Meox2mesenchyme homeobox 20.992
Pbx1pre B-cell leukemia transcription factor 10.991
Wt1Wilms tumor 1 homolog0.990
Fgf10fibroblast growth factor 100.990
Ptf1apancreas specific transcription factor, 1a0.989
Hand1heart and neural crest derivatives expressed transcript 10.989
Eya1eyes absent 1 homolog (Drosophila)0.988
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.987
Phox2bpaired-like homeobox 2b0.986
Neurod1neurogenic differentiation 10.985
Bmp4bone morphogenetic protein 40.984
Hoxa1homeobox A10.984
Hoxd3homeobox D30.983
Fgf8fibroblast growth factor 80.982
Msx2homeobox, msh-like 20.978
Emx1empty spiracles homolog 1 (Drosophila)0.975
Lhx3LIM homeobox protein 30.975
Retret proto-oncogene0.975
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.975
Lef1lymphoid enhancer binding factor 10.973
Rargretinoic acid receptor, gamma0.969
Foxc2forkhead box C20.967
Bmp7bone morphogenetic protein 70.963
Pax8paired box gene 80.962
Msx1homeobox, msh-like 10.962
Hoxa13homeobox A130.957
Sox11SRY-box containing gene 110.957
UncxUNC homeobox0.954
Sox9SRY-box containing gene 90.951
Foxg1forkhead box G10.950
Fgfr1fibroblast growth factor receptor 10.949
Gdnfglial cell line derived neurotrophic factor0.949
Hes1hairy and enhancer of split 1 (Drosophila)0.949
Fgf15fibroblast growth factor 150.949
Lmx1aLIM homeobox transcription factor 1 alpha0.948
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.946
Robo1roundabout homolog 1 (Drosophila)0.944
Hoxc6homeobox C60.943
Nhlh1nescient helix loop helix 10.939
En1engrailed 10.938
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.935
Hoxc4homeobox C40.928
Tal1T-cell acute lymphocytic leukemia 10.925
Gata4GATA binding protein 40.923
Hoxa9homeobox A90.914
Hoxa5homeobox A50.914
Hoxd11homeobox D110.914
Hoxa2homeobox A20.911
Rarbretinoic acid receptor, beta0.911
Hoxa3homeobox A30.906
Nr5a1nuclear receptor subfamily 5, group A, member 10.899
Sox3SRY-box containing gene 30.895
Prrx2paired related homeobox 20.893
Tlx3T-cell leukemia, homeobox 30.890
Insm1insulinoma-associated 10.886
Hoxb5homeobox B50.885
Hoxd10homeobox D100.884
Lmx1bLIM homeobox transcription factor 1 beta0.876
Wnt6wingless-related MMTV integration site 60.876
Mks1Meckel syndrome, type 10.875
Wnt4wingless-related MMTV integration site 40.872
Ror2receptor tyrosine kinase-like orphan receptor 20.851
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.845
Pitx1paired-like homeodomain transcription factor 10.844
Lhx5LIM homeobox protein 50.843
Pax7paired box gene 70.842
Notch1Notch gene homolog 1 (Drosophila)0.838
Nr2e1nuclear receptor subfamily 2, group E, member 10.838
Hoxd9homeobox D90.838
En2engrailed 20.828
Hes5hairy and enhancer of split 5 (Drosophila)0.826
Tbx1T-box 10.824
Wnt1wingless-related MMTV integration site 10.807
Hoxb2homeobox B20.807
Hoxb4homeobox B40.805
Socs1suppressor of cytokine signaling 10.790
Gbx2gastrulation brain homeobox 20.778
Onecut1one cut domain, family member 10.777
Foxd2forkhead box D20.773
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Kcnc3potassium voltage gated channel, Shaw-related subfamily, member 30.136
St18suppression of tumorigenicity 180.123
Kcnt1potassium channel, subfamily T, member 10.102
Unc5aunc-5 homolog A (C. elegans)0.095
Cntfrciliary neurotrophic factor receptor0.081
Mpp2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)0.069
Unc5bunc-5 homolog B (C. elegans)0.061
Dlgap3discs, large (Drosophila) homolog-associated protein 30.060
Dccdeleted in colorectal carcinoma0.059
Kcnq2potassium voltage-gated channel, KQT-like subfamily, member 20.056
Nlgn2neuroligin 20.056
Ecel1endothelin converting enzyme-like 10.054
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.054
Muskmuscle, skeletal, receptor tyrosine kinase0.052
Pou2f2POU class 2 homeobox 20.052
Grin3aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A0.049
Dlg4discs, large homolog 4 (Drosophila)0.048
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.047
Mobpmyelin-associated oligodendrocyte basic protein0.047
Oprl1opiate receptor-like 10.044
Nxph4neurexophilin 40.042
Sdc3syndecan 30.041
Fgfr2fibroblast growth factor receptor 20.039
Tnrtenascin R0.039
Adra2cadrenergic, alpha-2C-, receptor0.039
Crhr2corticotropin releasing hormone receptor 20.037
Arhgap28Rho GTPase activating protein 280.035
Myh3myosin, heavy chain 3, skeletal muscle, embryonic0.035
Syt9synaptotagmin IX0.035
Slc2a13solute carrier family 2 (facilitated glucose transporter), member 130.034
Myt1lmyelin transcription factor 1-like0.034
Cdh23cadherin 23 (otocadherin)0.033
Tacr1tachykinin receptor 10.032
Mpp3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)0.032
Pou3f2POU class 3 homeobox 20.031
Tpothyroid peroxidase0.031
Chrna7cholinergic receptor, nicotinic, alpha 70.031
Galr3galanin receptor 30.031
Slc8a2solute carrier family 8 (sodium/calcium exchanger), member 20.031
Tmod2tropomodulin 20.030
Znf532zinc finger protein 5320.030
Hoxc4homeo box C40.028
Ddr1discoidin domain receptor tyrosine kinase 10.028
Shank1SH3 and multiple ankyrin repeat domains 10.028
Phox2apaired-like homeobox 2a0.028
Dchs1dachsous 1 (Drosophila)0.027
Odf1outer dense fiber of sperm tails 10.027
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.026
Gng7guanine nucleotide binding protein (G protein), gamma 70.026
Tcfe2atranscription factor E2a0.026
Ppp2r2cprotein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform0.026
Efnb1ephrin B10.026
Barhl2BarH-like homeobox 20.026
Neurod2neurogenic differentiation 20.025
Kcnd2potassium voltage-gated channel, Shal-related subfamily, member 20.025
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.024
Magmyelin-associated glycoprotein0.024
Camk4calcium/calmodulin-dependent protein kinase IV0.024
Padi2peptidyl arginine deiminase, type II0.023
Chrna9cholinergic receptor, nicotinic, alpha 90.023
Drd1adopamine receptor D1A0.023
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.023
Grk1G protein-coupled receptor kinase 10.023
Amhanti-Mullerian hormone0.023
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.023
Ncam1neural cell adhesion molecule 10.022
RGD1566083similar to hypothetical protein MGC240470.022
Pcdha13protocadherin alpha 130.022
Rims1regulating synaptic membrane exocytosis 10.022
B3gat1beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)0.022
Gjb4gap junction protein, beta 40.022
Sbk1SH3-binding domain kinase 10.022
Grin2cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.022
Svs4seminal vesicle secretory protein 40.021
Fgf18fibroblast growth factor 180.021
Pex5lperoxisomal biogenesis factor 5-like0.021
Rcor2REST corepressor 20.020
Pax8paired box 80.020
Rimbp2RIMS binding protein 20.020
Foxc2forkhead box C20.020
Robo1roundabout homolog 1 (Drosophila)0.020
Cntn3contactin 3 (plasmacytoma associated)0.020
Rhbdl1rhomboid, veinlet-like 1 (Drosophila)0.019
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.019
Six3SIX homeobox 30.019
Ucn2urocortin 20.019
Fgf6fibroblast growth factor 60.019
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.018
Col8a1collagen, type VIII, alpha 10.018
Hist1h2aahistone cluster 1, H2aa0.018
Gabra1gamma-aminobutyric acid (GABA) A receptor, alpha 10.018
Prl8a2prolactin family 8, subfamily a, member 20.018
Epha7Eph receptor A70.018
Slit3slit homolog 3 (Drosophila)0.018
Ptgirprostaglandin I2 (prostacyclin) receptor (IP)0.018
Cdh4cadherin 40.017
Cercamcerebral endothelial cell adhesion molecule0.017
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism