The network for 'zygotic specification of dorsal ventral axis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

zygotic specification of dorsal ventral axis

The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote.

NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.780
l(2)gllethal (2) giant larvae0.037
Rho1CG8416 gene product from transcript CG8416-RB0.033
Stat92ESignal-transducer and activator of transcription protein at 92E0.028
mit(1)15mitotic 150.021
RnpS1RNA-binding protein S10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SMAD3SMAD family member 31.000
SMAD2SMAD family member 21.000
SMAD1SMAD family member 11.000
SMAD4SMAD family member 40.994
SMURF2SMAD specific E3 ubiquitin protein ligase 20.961
SKILSKI-like oncogene0.911
SMAD5SMAD family member 50.789
SMAD7SMAD family member 70.703
SKIv-ski sarcoma viral oncogene homolog (avian)0.513
SMURF1SMAD specific E3 ubiquitin protein ligase 10.358
CXXC5CXXC finger protein 50.282
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.163
ZFYVE9zinc finger, FYVE domain containing 90.069
PIAS4protein inhibitor of activated STAT, 40.061
SMAD9SMAD family member 90.061
TGFBR1transforming growth factor, beta receptor 10.059
TRAF4TNF receptor-associated factor 40.056
DCP1BDCP1 decapping enzyme homolog B (S. cerevisiae)0.050
PIAS1protein inhibitor of activated STAT, 10.049
NCOR1nuclear receptor corepressor 10.040
RNF11ring finger protein 110.033
FBXL15F-box and leucine-rich repeat protein 150.033
MUL1mitochondrial E3 ubiquitin protein ligase 10.028
ATF7IPactivating transcription factor 7 interacting protein0.025
ZBED5zinc finger, BED-type containing 50.025
NLKnemo-like kinase0.024
SREBF2sterol regulatory element binding transcription factor 20.021
WWP2WW domain containing E3 ubiquitin protein ligase 20.021
NEDD9neural precursor cell expressed, developmentally down-regulated 90.019
SOX7SRY (sex determining region Y)-box 70.019
BMPR1Abone morphogenetic protein receptor, type IA0.019
SP1Sp1 transcription factor0.019
MKL2MKL/myocardin-like 20.018
WWP1WW domain containing E3 ubiquitin protein ligase 10.018
PIAS2protein inhibitor of activated STAT, 20.018
VPS24vacuolar protein sorting 24 homolog (S. cerevisiae)0.017
HIPK2homeodomain interacting protein kinase 20.015
GMEB1glucocorticoid modulatory element binding protein 10.015
SPG20spastic paraplegia 20 (Troyer syndrome)0.015
SNRNP70small nuclear ribonucleoprotein 70kDa (U1)0.014
NEDD4neural precursor cell expressed, developmentally down-regulated 40.014
ZMYM2zinc finger, MYM-type 20.013
DACH1dachshund homolog 1 (Drosophila)0.012
TFPI2tissue factor pathway inhibitor 20.012
UHRF2ubiquitin-like with PHD and ring finger domains 20.012
SMAD6SMAD family member 60.012
YAP1Yes-associated protein 10.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism