The network for 'intermediate filament cytoskeleton organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

intermediate filament cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins.

NameDescriptionProbabilityFunc Analog Organism
phlpole hole0.701
Aos1CG12276 gene product from transcript CG12276-RA0.137
Caf1Chromatin assembly factor 1 subunit0.090
CG7028CG7028 gene product from transcript CG7028-RA0.074
modmodulo0.061
polybromoCG11375 gene product from transcript CG11375-RA0.040
CG12155CG12155 gene product from transcript CG12155-RA0.036
CG34415CG34415 gene product from transcript CG34415-RC0.033
Rpb5CG11979 gene product from transcript CG11979-RA0.033
RfC4Replication factor C subunit 40.028
BEAF-32Boundary element-associated factor of 32kD0.028
sspsunspot0.027
CG12129CG12129 gene product from transcript CG12129-RA0.022
Rca1Regulator of cyclin A10.022
MED20Mediator complex subunit 200.022
TfIIBTranscription factor IIB0.021
hhhedgehog0.021
Mcm7Minichromosome maintenance 70.021
tkvthickveins0.019
smt3CG4494 gene product from transcript CG4494-RA0.019
CG11444CG11444 gene product from transcript CG11444-RA0.019
TxlThioredoxin-like0.019
Rpb11CG6840 gene product from transcript CG6840-RA0.017
CG10465CG10465 gene product from transcript CG10465-RA0.017
Su(var)205Suppressor of variegation 2050.016
MED22Mediator complex subunit 220.016
crmcramped0.016
CG6459CG6459 gene product from transcript CG6459-RA0.015
CG12082CG12082 gene product from transcript CG12082-RA0.015
CG9135CG9135 gene product from transcript CG9135-RB0.014
CG2182CG2182 gene product from transcript CG2182-RA0.014
Tif-IACG3278 gene product from transcript CG3278-RA0.013
Tfb1CG8151 gene product from transcript CG8151-RB0.013
Art1Arginine methyltransferase 10.012
Arc-p34CG10954 gene product from transcript CG10954-RA0.012
exdextradenticle0.012
CAP-D2CAP-D2 condensin subunit0.012
Srp54CG4602 gene product from transcript CG4602-RA0.011
CG14220CG14220 gene product from transcript CG14220-RA0.011
RfC38Replication factor C 38kD subunit0.011
U2af38U2 small nuclear riboprotein auxiliary factor 380.011
PepProtein on ecdysone puffs0.011
eIF5CG9177 gene product from transcript CG9177-RE0.011
Prx5Peroxiredoxin 50.011
CG6610CG6610 gene product from transcript CG6610-RA0.011
l(3)01239lethal (3) 012390.011
gusgustavus0.011
CG11076CG11076 gene product from transcript CG11076-RB0.010
CG3226CG3226 gene product from transcript CG3226-RA0.010
CG18190CG18190 gene product from transcript CG18190-RB0.010
CG6841CG6841 gene product from transcript CG6841-RA0.010
mtTFB2mitochondrial transcription factor B20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
KRT15keratin 151.000
KRT6Bkeratin 6B0.999
KRT14keratin 140.988
PKP1plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)0.986
KRT19keratin 190.985
ERBB2IPerbb2 interacting protein0.978
KRT18keratin 180.977
UBQLN1ubiquilin 10.963
KRT17keratin 170.961
KRT8keratin 80.960
ITGB4integrin, beta 40.881
APCadenomatous polyposis coli0.869
KRT6Akeratin 6A0.866
EPS15epidermal growth factor receptor pathway substrate 150.849
DTNAdystrobrevin, alpha0.846
KRT5keratin 50.785
MTMR12myotubularin related protein 120.733
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.673
KRT34keratin 340.672
KRT1keratin 10.639
SMAD9SMAD family member 90.604
PSEN1presenilin 10.556
TP63tumor protein p630.550
MTM1myotubularin 10.516
PPP2R2Bprotein phosphatase 2, regulatory subunit B, beta0.446
HSPA8heat shock 70kDa protein 80.364
KRT33Bkeratin 33B0.337
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.335
PKP4plakophilin 40.333
SPRR1Asmall proline-rich protein 1A0.316
EXOC8exocyst complex component 80.307
KRT16keratin 160.240
KRT32keratin 320.238
DSPdesmoplakin0.226
SFNstratifin0.188
KRT36keratin 360.188
TOR1Atorsin family 1, member A (torsin A)0.184
CCDC85Bcoiled-coil domain containing 85B0.180
KRT75keratin 750.178
TRIM29tripartite motif containing 290.170
LAD1ladinin 10.169
PKP2plakophilin 20.160
JUPjunction plakoglobin0.135
KRT2keratin 20.133
KRT35keratin 350.132
ALBalbumin0.131
BAG1BCL2-associated athanogene0.129
KRT81keratin 810.125
DSG3desmoglein 30.124
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.115
KRT33Akeratin 33A0.107
SOS1son of sevenless homolog 1 (Drosophila)0.104
PHLPP1PH domain and leucine rich repeat protein phosphatase 10.103
KRT6Ckeratin 6C0.102
KRT9keratin 90.097
MARK3MAP/microtubule affinity-regulating kinase 30.096
DMDdystrophin0.095
IVLinvolucrin0.087
KRT13keratin 130.077
KIAA0408KIAA04080.076
TJP2tight junction protein 2 (zona occludens 2)0.076
SMAD4SMAD family member 40.076
TOR1AIP2torsin A interacting protein 20.075
TEKT4tektin 40.067
SLURP1secreted LY6/PLAUR domain containing 10.066
MTMR9myotubularin related protein 90.065
PTPRJprotein tyrosine phosphatase, receptor type, J0.062
KRT4keratin 40.062
KRT31keratin 310.058
KLK10kallikrein-related peptidase 100.057
COL17A1collagen, type XVII, alpha 10.056
SQSTM1sequestosome 10.056
FRMD5FERM domain containing 50.053
KIAA1217KIAA12170.052
KRT38keratin 380.051
SPRR1Bsmall proline-rich protein 1B0.049
NUMBnumb homolog (Drosophila)0.046
VIMvimentin0.044
PSEN2presenilin 2 (Alzheimer disease 4)0.044
TRIM63tripartite motif containing 630.043
ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific )0.043
TOR1Btorsin family 1, member B (torsin B)0.043
MAPK1mitogen-activated protein kinase 10.040
DSG1desmoglein 10.039
ATF7IPactivating transcription factor 7 interacting protein0.039
KRT37keratin 370.036
KIF5Bkinesin family member 5B0.031
S100A14S100 calcium binding protein A140.031
GADD45Agrowth arrest and DNA-damage-inducible, alpha0.030
MAP2K1mitogen-activated protein kinase kinase 10.030
RAD23BRAD23 homolog B (S. cerevisiae)0.029
SPTBN1spectrin, beta, non-erythrocytic 10.029
DSC3desmocollin 30.028
KRT85keratin 850.025
TJP1tight junction protein 1 (zona occludens 1)0.025
EXOC1exocyst complex component 10.024
LORloricrin0.023
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.023
HSPA13heat shock protein 70kDa family, member 130.023
LYPD3LY6/PLAUR domain containing 30.023
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Krt8keratin 80.997
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.989
Pplperiplakin0.957
Krt17keratin 170.949
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.948
Krt33bkeratin 33B0.928
Pkp1plakophilin 10.906
Krt14keratin 140.902
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.866
Krt6akeratin 6A0.851
Krt35keratin 350.817
Sprr1asmall proline-rich protein 1A0.809
Krt13keratin 130.740
Krt71keratin 710.714
Krt19keratin 190.709
Krt5keratin 50.668
Psapl1prosaposin-like 10.662
Foxn1forkhead box N10.661
Krt1keratin 10.642
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.601
Krt27keratin 270.590
Epha2Eph receptor A20.577
Wnt10awingless related MMTV integration site 10a0.563
Krt18keratin 180.556
Krt86keratin 860.539
Rpgrip1lRpgrip1-like0.533
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.524
Krt7keratin 70.490
Krt72-pskeratin 72, pseudogene0.484
Pitx1paired-like homeodomain transcription factor 10.471
Serpinb5serine (or cysteine) peptidase inhibitor, clade B, member 50.469
Krt85keratin 850.467
Tgm3transglutaminase 3, E polypeptide0.467
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.451
Desdesmin0.438
Nefmneurofilament, medium polypeptide0.371
Krtdapkeratinocyte differentiation associated protein0.364
Gfapglial fibrillary acidic protein0.364
Dlx3distal-less homeobox 30.350
Alox8arachidonate 8-lipoxygenase0.342
Hspa8heat shock protein 80.314
Lgals7lectin, galactose binding, soluble 70.293
Krtap6-2keratin associated protein 6-20.281
Krt75keratin 750.280
Pthlhparathyroid hormone-like peptide0.273
Egfrepidermal growth factor receptor0.263
Msx2homeobox, msh-like 20.259
Padi3peptidyl arginine deiminase, type III0.253
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.245
Krt25keratin 250.236
Fgf6fibroblast growth factor 60.234
Krtap8-1keratin associated protein 8-10.230
Cdsncorneodesmosin0.226
Krt77keratin 770.223
Klk6kallikrein related-peptidase 60.219
Sox10SRY-box containing gene 100.216
Bdnfbrain derived neurotrophic factor0.214
Krt15keratin 150.205
Trp63transformation related protein 630.203
Syt8synaptotagmin VIII0.203
S100a14S100 calcium binding protein A140.200
Capn8calpain 80.196
S100a3S100 calcium binding protein A30.194
Sfnstratifin0.185
Sox9SRY-box containing gene 90.180
Syncsyncoilin0.166
5430421N21RikRIKEN cDNA 5430421N21 gene0.166
Kcns2K+ voltage-gated channel, subfamily S, 20.164
Wfdc2WAP four-disulfide core domain 20.163
Krt34keratin 340.159
Krt6bkeratin 6B0.158
Tff1trefoil factor 10.156
Fxyd3FXYD domain-containing ion transport regulator 30.154
Krt33akeratin 33A0.153
Krt36keratin 360.153
Krt32keratin 320.152
Krt82keratin 820.147
Lypd3Ly6/Plaur domain containing 30.143
Krt84keratin 840.142
Dspdesmoplakin0.132
Sprr3small proline-rich protein 30.128
Prss1protease, serine, 1 (trypsin 1)0.124
Gjb4gap junction protein, beta 40.123
Endouendonuclease, polyU-specific0.122
Hrhairless0.121
Zp2zona pellucida glycoprotein 20.121
Ly6g6clymphocyte antigen 6 complex, locus G6C0.121
Trim29tripartite motif-containing 290.121
Il1f5interleukin 1 family, member 5 (delta)0.120
Krt16keratin 160.119
Krt81keratin 810.118
Krtap3-3keratin associated protein 3-30.115
Clic3chloride intracellular channel 30.114
Krt4keratin 40.113
Calm4calmodulin 40.112
Bmp7bone morphogenetic protein 70.112
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.111
Edn2endothelin 20.109
Ndel1nuclear distribution gene E-like homolog 1 (A. nidulans)0.108
Cldn4claudin 40.105
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Nefhneurofilament, heavy polypeptide0.150
Fn1fibronectin 10.051
Anxa2annexin A20.037
Nefmneurofilament, medium polypeptide0.028
Inainternexin neuronal intermediate filament protein, alpha0.026
Sparcsecreted protein, acidic, cysteine-rich (osteonectin)0.026
Anxa5annexin A50.021
Neflneurofilament, light polypeptide0.019
Klk6kallikrein related-peptidase 60.019
Csrp3cysteine and glycine-rich protein 30.019
Col5a2collagen, type V, alpha 20.017
Taglntransgelin0.016
CadpsCa++-dependent secretion activator0.016
Tbcbtubulin folding cofactor B0.013
Slc16a3solute carrier family 16, member 3 (monocarboxylic acid transporter 4)0.012
Hspb1heat shock protein 10.012
Mgpmatrix Gla protein0.012
Fgf9fibroblast growth factor 90.012
Cox8acytochrome c oxidase subunit VIIIa0.012
Crabp1cellular retinoic acid binding protein 10.012
Cplx1complexin 10.012
Kif5ckinesin family member 5C0.011
Hspb2heat shock protein beta 20.011
Sncasynuclein, alpha (non A4 component of amyloid precursor)0.011
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.011
Uchl1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.010
Cryabcrystallin, alpha B0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism