The network for 'nerve development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nerve development

The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
E(spl)Enhancer of split0.984
HLHm7E(spl) region transcript m70.976
HLHmdeltaE(spl) region transcript mdelta0.836
HLHm5E(spl) region transcript m50.833
HLHmgammaE(spl) region transcript mgamma0.683
HLHmbetaE(spl) region transcript mbeta0.642
malphaE(spl) region transcript malpha0.423
HLHm3E(spl) region transcript m30.368
argosCG4531 gene product from transcript CG4531-RA0.217
stcksteamer duck0.217
vvlventral veins lacking0.204
PoxnPox neuro0.106
norpAno receptor potential A0.092
m4E(spl) region transcript m40.090
m2E(spl) region transcript m20.089
salmspalt major0.083
cicubitus interruptus0.082
TomTwin of m40.078
WnkCG7177 gene product from transcript CG7177-RA0.077
CG12424CG12424 gene product from transcript CG12424-RC0.077
bowlbrother of odd with entrails limited0.060
shotshort stop0.059
Fas2Fasciclin 20.053
nocno ocelli0.053
witwishful thinking0.052
amosabsent MD neurons and olfactory sensilla0.051
CkIIalphaCasein kinase II alpha subunit0.046
trioCG18214 gene product from transcript CG18214-RA0.038
SmoxSmad on X0.036
stanstarry night0.034
CaMKIICalcium/calmodulin-dependent protein kinase II0.033
Ten-aTenascin accessory0.032
danrdistal antenna-related0.030
Nrx-IVNeurexin IV0.021
eyaeyes absent0.021
MicalMolecule interacting with CasL0.020
Irk2Inwardly rectifying potassium channel 20.020
Fak56DFocal Adhesion Kinase0.018
Sema-1aCG18405 gene product from transcript CG18405-RD0.018
vavCG7893 gene product from transcript CG7893-RB0.017
Jarid2CG3654 gene product from transcript CG3654-RD0.017
TolloCG6890 gene product from transcript CG6890-RA0.017
Ten-mTenascin major0.016
CG5508CG5508 gene product from transcript CG5508-RA0.016
wbwing blister0.014
reporeversed polarity0.014
mbcmyoblast city0.013
LanB2Laminin B20.013
Syx1ASyntaxin 1A0.013
Cpr97EbCuticular protein 97Eb0.013
IdeInsulin degrading metalloproteinase0.012
zfh2Zn finger homeodomain 20.012
Applbeta amyloid protein precursor-like0.012
dallydivision abnormally delayed0.012
fbl6CG13213 gene product from transcript CG13213-RB0.011
NotumCG13076 gene product from transcript CG13076-RB0.011
Rya-r44FRyanodine receptor 44F0.011
HimHoles in muscle0.011
Mmp2Matrix metalloproteinase 20.011
Ca-alpha1DCa[2+]-channel protein alpha[[1]] subunit D0.011
dandistal antenna0.011
lbeladybird early0.010
CG8963CG8963 gene product from transcript CG8963-RB0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sox10SRY-box containing gene 100.987
tbx1T-box 10.969
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.860
alcamaactivated leukocyte cell adhesion molecule a0.830
atoh1aatonal homolog 1a0.791
pax2apaired box gene 2a0.781
six3asine oculis homeobox homolog 3a0.750
emx3empty spiracles homeobox 30.734
cntn2contactin 20.715
ptf1apancreas specific transcription factor, 1a0.683
dlx4adistal-less homeobox gene 4a0.674
dlx4bdistal-less homeobox gene 4b0.668
cdh2cadherin 2, neuronal0.658
atoh1batonal homolog 1b0.634
phox2apaired-like homeobox 2a0.617
fgf10afibroblast growth factor 10a0.549
fn1fibronectin 10.521
st8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.504
grem2gremlin 2, cysteine knot superfamily0.493
foxi1forkhead box I10.466
neurodneurogenic differentiation0.448
otx1borthodenticle homolog 1b0.436
gata2aGATA-binding protein 2a0.400
six3bsine oculis homeobox homolog 3b0.387
hoxb3ahomeo box B3a0.385
foxa2forkhead box A20.374
eya1eyes absent homolog 10.322
lhx3LIM homeobox 30.307
fgf8afibroblast growth factor 8 a0.307
egr2bearly growth response 2b0.289
dlx3bdistal-less homeobox gene 3b0.283
robo1roundabout homolog 10.282
kitbkit receptor b0.272
hmx4H6 family homeobox 40.271
six4bsine oculis homeobox homolog 4b0.269
shhasonic hedgehog a0.259
tubb5tubulin, beta 50.254
dlx2adistal-less homeobox gene 2a0.244
lmx1b.1LIM homeobox transcription factor 1, beta 10.243
pax6bpaired box gene 6b0.239
gli2aGLI-Kruppel family member GLI2a0.238
lhx2bLIM homeobox 2b0.235
gata3GATA-binding protein 30.233
hoxb1bhomeo box B1b0.228
nr2e1nuclear receptor subfamily 2, group E, member 10.226
barhl2BarH-like 20.225
rx3retinal homeobox gene 30.222
foxd3forkhead box D30.220
olfm2olfactomedin 20.218
pitx2paired-like homeodomain transcription factor 20.218
dlx2bdistal-less homeobox gene 2b0.218
bocbrother of CDO0.213
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.210
tgfb3transforming growth factor, beta 30.209
neurod4neurogenic differentiation 40.206
ptpraprotein tyrosine phosphatase, receptor type, A0.205
fstafollistatin a0.197
myod1myogenic differentiation 10.196
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.194
sox21bSRY-box containing gene 21 b0.193
ndr2nodal-related 20.192
pou3f3aPOU class 3 homeobox 3a0.192
ret1receptor tyrosine kinase0.191
sox9aSRY-box containing gene 9a0.190
hoxa3ahomeo box A3a0.190
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.185
dlx1adistal-less homeobox gene 1a0.185
mpzmyelin protein zero0.180
hoxb4ahomeo box B4a0.174
scn8aasodium channel, voltage-gated, type VIII, alpha a0.174
stmn2bstathmin-like 2b0.173
smad1MAD homolog 1 (Drosophila)0.168
foxi3aforkhead box I3a0.167
fgfr2fibroblast growth factor receptor 20.164
barhl1.2BarH-like 1.20.164
ascl1aachaete-scute complex-like 1a (Drosophila)0.162
kbpkif1-binding protein0.161
dlx6adistal-less homeobox gene 6a0.159
fabp7afatty acid binding protein 7, brain, a0.155
nos1nitric oxide synthase 1 (neuronal)0.149
sulf1sulfatase 10.149
jam2bjunctional adhesion molecule 2b0.148
nkx2.1aNK2 homeobox 1a0.148
cadm3cell adhesion molecule 30.147
hey1hairy/enhancer-of-split related with YRPW motif 10.143
neurog1neurogenin 10.141
otpborthopedia homolog b0.137
hapln1ahyaluronan and proteoglycan link protein 1a0.131
cdh4cadherin 4, retinal0.130
nkx2.3NK2 transcription factor related 30.129
olig2oligodendrocyte lineage transcription factor 20.125
mibmind bomb0.125
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)1.000
EGFRepidermal growth factor receptor1.000
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1.000
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence1.000
SYKspleen tyrosine kinase0.994
POU5F1POU class 5 homeobox 10.973
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.954
GRB7growth factor receptor-bound protein 70.940
CHD8chromodomain helicase DNA binding protein 80.919
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.918
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.908
PLCG1phospholipase C, gamma 10.878
TNRC6Btrinucleotide repeat containing 6B0.877
EIF2C1eukaryotic translation initiation factor 2C, 10.875
SETD8SET domain containing (lysine methyltransferase) 80.850
STK36serine/threonine kinase 360.849
VEGFAvascular endothelial growth factor A0.837
CHD7chromodomain helicase DNA binding protein 70.801
DTNAdystrobrevin, alpha0.741
ZFYVE9zinc finger, FYVE domain containing 90.739
PPARAperoxisome proliferator-activated receptor alpha0.738
INSRinsulin receptor0.732
SHC1SHC (Src homology 2 domain containing) transforming protein 10.724
SOX2SRY (sex determining region Y)-box 20.708
NOXA1NADPH oxidase activator 10.702
NGFnerve growth factor (beta polypeptide)0.700
GATA2GATA binding protein 20.672
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.660
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.640
BAZ2Bbromodomain adjacent to zinc finger domain, 2B0.630
COL4A3BPcollagen, type IV, alpha 3 (Goodpasture antigen) binding protein0.625
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.599
PTCH1patched 10.568
NTRK1neurotrophic tyrosine kinase, receptor, type 10.568
TCF12transcription factor 120.565
SUFUsuppressor of fused homolog (Drosophila)0.559
NR4A1nuclear receptor subfamily 4, group A, member 10.504
KLF4Kruppel-like factor 4 (gut)0.496
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.480
HOXA5homeobox A50.465
HOXB5homeobox B50.456
LATlinker for activation of T cells0.452
DDR2discoidin domain receptor tyrosine kinase 20.448
POU4F2POU class 4 homeobox 20.437
HOXA4homeobox A40.435
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.425
FGBfibrinogen beta chain0.421
MRPS22mitochondrial ribosomal protein S220.413
TMSB4Xthymosin beta 4, X-linked0.411
RBBP5retinoblastoma binding protein 50.409
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.388
TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.385
EPHB1EPH receptor B10.368
MYCNv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.359
FGF1fibroblast growth factor 1 (acidic)0.358
RUNX1runt-related transcription factor 10.336
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.329
TNRC6Ctrinucleotide repeat containing 6C0.328
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.325
SOX13SRY (sex determining region Y)-box 130.321
PROX1prospero homeobox 10.321
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.317
HOXA3homeobox A30.311
ACTN1actinin, alpha 10.306
DTNBdystrobrevin, beta0.295
PTK6PTK6 protein tyrosine kinase 60.292
PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.292
HAND2heart and neural crest derivatives expressed 20.289
ZIC1Zic family member 1 (odd-paired homolog, Drosophila)0.288
PARVAparvin, alpha0.281
HOXD12homeobox D120.281
MYT1myelin transcription factor 10.279
MDFIMyoD family inhibitor0.279
FGFR1fibroblast growth factor receptor 10.276
LIMS1LIM and senescent cell antigen-like domains 10.273
STMN2stathmin-like 20.263
PAX6paired box 60.260
DUSP23dual specificity phosphatase 230.256
ACP5acid phosphatase 5, tartrate resistant0.254
HIC1hypermethylated in cancer 10.247
JUNjun proto-oncogene0.244
PDX1pancreatic and duodenal homeobox 10.242
DAB1disabled homolog 1 (Drosophila)0.238
SIX6SIX homeobox 60.236
MYH9myosin, heavy chain 9, non-muscle0.235
TGIF1TGFB-induced factor homeobox 10.233
HDAC11histone deacetylase 110.225
DYNC1I1dynein, cytoplasmic 1, intermediate chain 10.225
SH3BP4SH3-domain binding protein 40.222
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.221
CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 30.220
HOXB3homeobox B30.219
HOXA11homeobox A110.208
FGF2fibroblast growth factor 2 (basic)0.206
HOXD13homeobox D130.206
PAX3paired box 30.205
SIM2single-minded homolog 2 (Drosophila)0.205
TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta)0.202
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Otx2orthodenticle homolog 2 (Drosophila)1.000
Ntrk2neurotrophic tyrosine kinase, receptor, type 21.000
Shhsonic hedgehog0.999
Hoxa1homeobox A10.999
Pax2paired box gene 20.992
Gli3GLI-Kruppel family member GLI30.980
Fgfr2fibroblast growth factor receptor 20.979
Isl1ISL1 transcription factor, LIM/homeodomain0.977
Bdnfbrain derived neurotrophic factor0.975
Phox2bpaired-like homeobox 2b0.969
Sox2SRY-box containing gene 20.967
Msx2homeobox, msh-like 20.963
Pax6paired box gene 60.962
Tcfap2atranscription factor AP-2, alpha0.946
Eya1eyes absent 1 homolog (Drosophila)0.936
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.935
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.932
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.928
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.924
Gdnfglial cell line derived neurotrophic factor0.916
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.898
Grid1glutamate receptor, ionotropic, delta 10.891
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.884
Retret proto-oncogene0.883
Ntf3neurotrophin 30.874
Dlx5distal-less homeobox 50.854
Pax3paired box gene 30.854
Ascl1achaete-scute complex homolog 1 (Drosophila)0.840
Neurog1neurogenin 10.836
Hoxb1homeobox B10.834
Lhx9LIM homeobox protein 90.829
En2engrailed 20.822
Pou4f2POU domain, class 4, transcription factor 20.805
Msx1homeobox, msh-like 10.778
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.774
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.771
Hspg2perlecan (heparan sulfate proteoglycan 2)0.769
Hoxd3homeobox D30.763
Emx2empty spiracles homolog 2 (Drosophila)0.757
Otx1orthodenticle homolog 1 (Drosophila)0.750
Sall4sal-like 4 (Drosophila)0.744
Emx1empty spiracles homolog 1 (Drosophila)0.726
Lhx1LIM homeobox protein 10.721
Lhx3LIM homeobox protein 30.707
Gria4glutamate receptor, ionotropic, AMPA4 (alpha 4)0.688
Foxc1forkhead box C10.685
Fgfr3fibroblast growth factor receptor 30.663
Gabra2gamma-aminobutyric acid (GABA) A receptor, subunit alpha 20.660
Foxg1forkhead box G10.660
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.653
Wnt6wingless-related MMTV integration site 60.652
Fgf8fibroblast growth factor 80.636
Hand1heart and neural crest derivatives expressed transcript 10.618
Ednraendothelin receptor type A0.617
Efnb2ephrin B20.610
En1engrailed 10.609
UncxUNC homeobox0.607
Neurod1neurogenic differentiation 10.600
Fgf3fibroblast growth factor 30.598
Fgf10fibroblast growth factor 100.584
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.576
Hoxb3homeobox B30.573
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.564
Tbx3T-box 30.558
Sema3fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.537
Chd7chromodomain helicase DNA binding protein 70.531
Gabrb2gamma-aminobutyric acid (GABA) A receptor, subunit beta 20.524
Egr2early growth response 20.512
Hand2heart and neural crest derivatives expressed transcript 20.501
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.496
Pitx1paired-like homeodomain transcription factor 10.493
Tlx3T-cell leukemia, homeobox 30.483
Bcl2B-cell leukemia/lymphoma 20.471
Gabra1gamma-aminobutyric acid (GABA) A receptor, subunit alpha 10.471
Gad2glutamic acid decarboxylase 20.463
Hmx1H6 homeobox 10.456
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.439
Apcadenomatosis polyposis coli0.426
Sall3sal-like 3 (Drosophila)0.422
Pou4f3POU domain, class 4, transcription factor 30.420
Prox1prospero-related homeobox 10.407
Pou5f1POU domain, class 5, transcription factor 10.400
Foxc2forkhead box C20.395
Nrg1neuregulin 10.391
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.387
Myod1myogenic differentiation 10.384
Ror1receptor tyrosine kinase-like orphan receptor 10.381
Lmx1aLIM homeobox transcription factor 1 alpha0.378
Pitx2paired-like homeodomain transcription factor 20.378
Cdh10cadherin 100.378
Kcna6potassium voltage-gated channel, shaker-related, subfamily, member 60.377
Chrnb4cholinergic receptor, nicotinic, beta polypeptide 40.370
Nxph1neurexophilin 10.364
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.359
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.353
Neurog2neurogenin 20.351
Zic1zinc finger protein of the cerebellum 10.350
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Egr1early growth response 10.173
Lrrc15leucine rich repeat containing 150.045
Lgals3lectin, galactoside-binding, soluble, 30.036
Muskmuscle, skeletal, receptor tyrosine kinase0.035
Atp1b3ATPase, Na+/K+ transporting, beta 3 polypeptide0.035
Gja1gap junction protein, alpha 10.031
Anxa1annexin A10.029
Mobpmyelin-associated oligodendrocyte basic protein0.029
Ageradvanced glycosylation end product-specific receptor0.026
Lamp2lysosomal-associated membrane protein 20.024
Trpc4transient receptor potential cation channel, subfamily C, member 40.024
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.024
Gabra3gamma-aminobutyric acid (GABA) A receptor, alpha 30.023
Nfibnuclear factor I/B0.021
Kcnc1potassium voltage gated channel, Shaw-related subfamily, member 10.021
Phkg1phosphorylase kinase, gamma 10.020
Tuba1btubulin, alpha 1B0.020
Anxa2annexin A20.018
S100a10S100 calcium binding protein A100.018
Neflneurofilament, light polypeptide0.017
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.017
P2rx6purinergic receptor P2X, ligand-gated ion channel, 60.017
Nr4a1nuclear receptor subfamily 4, group A, member 10.017
Ctsl1cathepsin L10.016
Galr1galanin receptor 10.016
Cd9CD9 molecule0.015
Prl8a2prolactin family 8, subfamily a, member 20.015
Slc28a1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.015
Gabra1gamma-aminobutyric acid (GABA) A receptor, alpha 10.015
Gria1glutamate receptor, ionotropic, AMPA 10.015
Myo9amyosin IXA0.015
Hspa1lheat shock protein 1-like0.015
Gpr85G protein-coupled receptor 850.014
Nox1NADPH oxidase 10.014
Fshbfollicle stimulating hormone, beta polypeptide0.014
Scnn1gsodium channel, nonvoltage-gated 1, gamma0.014
Adra2cadrenergic, alpha-2C-, receptor0.014
Kcna6potassium voltage gated channel, shaker related subfamily, member 60.014
Tagln3transgelin 30.014
Plcd4phospholipase C, delta 40.014
Gria4glutamate receptor, ionotrophic, AMPA 40.014
Appamyloid beta (A4) precursor protein0.014
Fgf23fibroblast growth factor 230.013
Prg2proteoglycan 2, bone marrow0.013
Irx4iroquois homeobox 40.013
Fgf16fibroblast growth factor 160.013
Snap91synaptosomal-associated protein 910.013
Asb12ankyrin repeat and SOCS box-containing 120.013
Foxq1forkhead box Q10.013
RGD1563263similar to RIKEN cDNA 1700029I150.013
Kcnt1potassium channel, subfamily T, member 10.013
Calb2calbindin 20.013
Folh1folate hydrolase 10.012
P2ry4pyrimidinergic receptor P2Y, G-protein coupled, 40.012
Ntsr2neurotensin receptor 20.012
Rpe65retinal pigment epithelium 650.012
UncxUNC homeobox0.012
Dab2disabled homolog 2 (Drosophila)0.012
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.012
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.012
Adcy5adenylate cyclase 50.012
Ecel1endothelin converting enzyme-like 10.012
Mogmyelin oligodendrocyte glycoprotein0.012
Fgf14fibroblast growth factor 140.011
Oxtoxytocin, prepropeptide0.011
F2rl3coagulation factor II (thrombin) receptor-like 30.011
Anxa5annexin A50.011
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.011
Esr1estrogen receptor 10.011
Cd63Cd63 molecule0.011
Trim9tripartite motif-containing 90.011
Maged2melanoma antigen, family D, 20.011
Opn1swopsin 1 (cone pigments), short-wave-sensitive0.010
Fgf8fibroblast growth factor 80.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism