The network for 'positive regulation of binding' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of binding

Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.

NameDescriptionProbabilityFunc Analog Organism
SmFSmall ribonucleoprotein particle protein SmF0.016
U2af50U2 small nuclear riboprotein auxiliary factor 500.016
stisticky0.015
CG5114CG5114 gene product from transcript CG5114-RA0.015
dbedribble0.015
Caf1Chromatin assembly factor 1 subunit0.015
CG13779CG13779 gene product from transcript CG13779-RA0.015
CG9548CG9548 gene product from transcript CG9548-RA0.014
l(1)G0020lethal (1) G00200.014
CG11563CG11563 gene product from transcript CG11563-RA0.014
FK506-bp2FK506-binding protein 20.014
Pka-R1cAMP-dependent protein kinase R10.014
Aos1CG12276 gene product from transcript CG12276-RA0.013
RnpS1RNA-binding protein S10.013
CG10576CG10576 gene product from transcript CG10576-RA0.013
borrborealin-related0.013
mRpS2mitochondrial ribosomal protein S20.013
CG9630CG9630 gene product from transcript CG9630-RA0.013
Arp14DActin-related protein 14D0.013
MybMyb oncogene-like0.013
CG14482CG14482 gene product from transcript CG14482-RA0.013
sggshaggy0.013
RpII33RNA polymerase II 33kD subunit0.013
mskmoleskin0.012
CG6724CG6724 gene product from transcript CG6724-RA0.012
CG1707CG1707 gene product from transcript CG1707-RA0.012
csulcapsuleen0.012
CG6180CG6180 gene product from transcript CG6180-RA0.012
Mcm7Minichromosome maintenance 70.012
Trf2TATA box binding protein-related factor 20.012
Vha68-2CG3762 gene product from transcript CG3762-RA0.012
eIF6CG17611 gene product from transcript CG17611-RA0.012
CG7993CG7993 gene product from transcript CG7993-RA0.012
CG12079CG12079 gene product from transcript CG12079-RA0.012
modmodulo0.012
Vha36CG8186 gene product from transcript CG8186-RA0.012
Gp150CG5820 gene product from transcript CG5820-RA0.012
feofascetto0.012
tumtumbleweed0.012
Arp66BActin-related protein 66B0.012
Rpt1CG1341 gene product from transcript CG1341-RA0.012
MED22Mediator complex subunit 220.012
CG4866CG4866 gene product from transcript CG4866-RB0.012
Ski6CG15481 gene product from transcript CG15481-RA0.012
CG5800CG5800 gene product from transcript CG5800-RA0.012
Nedd8CG10679 gene product from transcript CG10679-RA0.012
HHairless0.012
gemininCG3183 gene product from transcript CG3183-RA0.011
chicoCG5686 gene product from transcript CG5686-RB0.011
Ranbp9CG5252 gene product from transcript CG5252-RA0.011
l(2)gd1lethal (2) giant discs 10.011
l(2)03709lethal (2) 037090.011
mspsmini spindles0.011
RfC38Replication factor C 38kD subunit0.011
Eip93FCG18389 gene product from transcript CG18389-RB0.011
laceCG4162 gene product from transcript CG4162-RA0.011
didumdilute class unconventional myosin0.011
reptreptin0.011
Atg18Autophagy-specific gene 180.011
pitaCG3941 gene product from transcript CG3941-RA0.011
mmymummy0.011
tlkTousled-like kinase0.011
fufused0.011
CstF-50CG2261 gene product from transcript CG2261-RA0.011
CG6961CG6961 gene product from transcript CG6961-RA0.011
Cbp20cap binding protein 200.011
CG9140CG9140 gene product from transcript CG9140-RA0.011
hoiphoi-polloi0.011
CycB3Cyclin B30.011
FibFibrillarin0.011
hdcheadcase0.011
CG7006CG7006 gene product from transcript CG7006-RA0.011
Ras85DRas oncogene at 85D0.011
poloCG12306 gene product from transcript CG12306-RA0.011
CycBCyclin B0.011
Smnsurvival motor neuron0.011
CG4882CG4882 gene product from transcript CG4882-RA0.011
DlDelta0.011
RhoGAP92BCG4755 gene product from transcript CG4755-RA0.011
TsCG3181 gene product from transcript CG3181-RA0.011
l(1)G0255lethal (1) G02550.011
Cyt-c-pCytochrome c proximal0.011
CG6020CG6020 gene product from transcript CG6020-RA0.011
stcksteamer duck0.011
CG6116CG6116 gene product from transcript CG6116-RA0.011
CctgammaCG8977 gene product from transcript CG8977-RC0.011
auraurora0.011
Dbp73DDead box protein 73D0.011
CG7375CG7375 gene product from transcript CG7375-RA0.011
ctpcut up0.011
CG3731CG3731 gene product from transcript CG3731-RA0.011
spagspaghetti0.011
cpacapping protein alpha0.011
CG9286CG9286 gene product from transcript CG9286-RA0.011
PsnPresenilin0.011
CG8924CG8924 gene product from transcript CG8924-RB0.011
slikSterile20-like kinase0.010
pcmpacman0.010
cypecyclope0.010
CkIIalphaCasein kinase II alpha subunit0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.922
SMAD3SMAD family member 30.756
TAL1T-cell acute lymphocytic leukemia 10.494
RARAretinoic acid receptor, alpha0.460
TRAF3TNF receptor-associated factor 30.340
TGFB1transforming growth factor, beta 10.322
RXRAretinoid X receptor, alpha0.318
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.317
ANXA2annexin A20.300
CREBBPCREB binding protein0.267
SETD8SET domain containing (lysine methyltransferase) 80.242
SOD1superoxide dismutase 1, soluble0.206
TICAM2toll-like receptor adaptor molecule 20.198
SPTBspectrin, beta, erythrocytic0.196
GGA3golgi-associated, gamma adaptin ear containing, ARF binding protein 30.189
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.181
ZNF260zinc finger protein 2600.180
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.179
TUBBtubulin, beta0.173
TRAF1TNF receptor-associated factor 10.159
TGFBR1transforming growth factor, beta receptor 10.142
ZNF420zinc finger protein 4200.141
HMGA1high mobility group AT-hook 10.140
PKD2polycystic kidney disease 2 (autosomal dominant)0.139
TUBA1Btubulin, alpha 1b0.133
SUMO2SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)0.128
PRMT6protein arginine methyltransferase 60.125
SMURF1SMAD specific E3 ubiquitin protein ligase 10.117
TUBA1Ctubulin, alpha 1c0.117
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.116
SOCS1suppressor of cytokine signaling 10.115
TRAF2TNF receptor-associated factor 20.113
PRDX1peroxiredoxin 10.112
PPIApeptidylprolyl isomerase A (cyclophilin A)0.107
ESR1estrogen receptor 10.104
SMAD7SMAD family member 70.103
LDHAlactate dehydrogenase A0.100
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.098
RUNX1runt-related transcription factor 10.094
HIC1hypermethylated in cancer 10.093
ZNF512Bzinc finger protein 512B0.092
ZMYND11zinc finger, MYND-type containing 110.087
ACVR1Bactivin A receptor, type IB0.086
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase0.086
LMO2LIM domain only 2 (rhombotin-like 1)0.085
ZNF84zinc finger protein 840.083
S100A10S100 calcium binding protein A100.082
TADA3transcriptional adaptor 30.081
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.077
SMAD1SMAD family member 10.076
MYD88myeloid differentiation primary response gene (88)0.073
BCL9B-cell CLL/lymphoma 90.071
ZNF302zinc finger protein 3020.071
ZNF585Azinc finger protein 585A0.070
EP300E1A binding protein p3000.070
ZNF571zinc finger protein 5710.069
SMAD2SMAD family member 20.068
ITGB1BP3integrin beta 1 binding protein 30.067
TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)0.066
SELSselenoprotein S0.065
DCAF7DDB1 and CUL4 associated factor 70.064
RCC1regulator of chromosome condensation 10.064
ZNF567zinc finger protein 5670.064
CFL1cofilin 1 (non-muscle)0.062
RFX1regulatory factor X, 1 (influences HLA class II expression)0.062
CD40CD40 molecule, TNF receptor superfamily member 50.060
ANXA1annexin A10.059
LRP6low density lipoprotein receptor-related protein 60.059
NR1H3nuclear receptor subfamily 1, group H, member 30.059
BIRC3baculoviral IAP repeat containing 30.058
HSPA8heat shock 70kDa protein 80.058
WRNWerner syndrome, RecQ helicase-like0.058
CSNK1A1casein kinase 1, alpha 10.057
FSTL1follistatin-like 10.057
ACTBactin, beta0.054
NCOR2nuclear receptor corepressor 20.053
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.053
ZNF529zinc finger protein 5290.052
FZD1frizzled homolog 1 (Drosophila)0.052
RIPK2receptor-interacting serine-threonine kinase 20.052
GATA2GATA binding protein 20.050
TCF4transcription factor 40.050
ZFPM1zinc finger protein, multitype 10.048
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.047
C8orf33chromosome 8 open reading frame 330.047
HDAC4histone deacetylase 40.046
SIN3ASIN3 homolog A, transcription regulator (yeast)0.046
SMAD4SMAD family member 40.046
HOOK2hook homolog 2 (Drosophila)0.046
ZNF569zinc finger protein 5690.045
PGAM1phosphoglycerate mutase 1 (brain)0.045
MYOD1myogenic differentiation 10.045
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.044
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.044
MMP1matrix metallopeptidase 1 (interstitial collagenase)0.043
SEMA4Asema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A0.043
FAF1Fas (TNFRSF6) associated factor 10.043
TIMP2TIMP metallopeptidase inhibitor 20.042
MTA1metastasis associated 10.042
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.042
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Emx2empty spiracles homolog 2 (Drosophila)0.841
En1engrailed 10.806
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.689
Emx1empty spiracles homolog 1 (Drosophila)0.670
Rargretinoic acid receptor, gamma0.640
Arid1aAT rich interactive domain 1A (SWI-like)0.610
Rb1retinoblastoma 10.589
Meox2mesenchyme homeobox 20.582
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.572
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.562
Pkd1polycystic kidney disease 1 homolog0.561
S100a9S100 calcium binding protein A9 (calgranulin B)0.542
Nrp1neuropilin 10.522
Fgfr1fibroblast growth factor receptor 10.514
S100a8S100 calcium binding protein A8 (calgranulin A)0.513
Arrb1arrestin, beta 10.487
Csf1colony stimulating factor 1 (macrophage)0.451
Tbx1T-box 10.399
Otx2orthodenticle homolog 2 (Drosophila)0.395
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.391
Shhsonic hedgehog0.369
Pitx2paired-like homeodomain transcription factor 20.351
Axin1axin 10.312
Zeb1zinc finger E-box binding homeobox 10.311
Fgf8fibroblast growth factor 80.305
Spna2spectrin alpha 20.295
Fgfr2fibroblast growth factor receptor 20.290
Tbx3T-box 30.288
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.284
Gsk3bglycogen synthase kinase 3 beta0.283
Isl1ISL1 transcription factor, LIM/homeodomain0.283
Bmpr1abone morphogenetic protein receptor, type 1A0.283
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.263
Myd88myeloid differentiation primary response gene 880.224
Mdm2transformed mouse 3T3 cell double minute 20.222
Gli3GLI-Kruppel family member GLI30.218
Pax3paired box gene 30.217
Ebf3early B-cell factor 30.216
Ascl1achaete-scute complex homolog 1 (Drosophila)0.214
Ncor2nuclear receptor co-repressor 20.211
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.206
S100a11S100 calcium binding protein A11 (calgizzarin)0.198
Lrp6low density lipoprotein receptor-related protein 60.197
Hes1hairy and enhancer of split 1 (Drosophila)0.196
Spnb2spectrin beta 20.194
Ptenphosphatase and tensin homolog0.194
Gnb1guanine nucleotide binding protein (G protein), beta 10.192
Thrathyroid hormone receptor alpha0.192
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.186
Rxraretinoid X receptor alpha0.186
Lhx3LIM homeobox protein 30.186
Invsinversin0.174
Dag1dystroglycan 10.174
Wnt1wingless-related MMTV integration site 10.170
S100a6S100 calcium binding protein A6 (calcyclin)0.166
Neurog3neurogenin 30.164
Gbx2gastrulation brain homeobox 20.164
Acvr1activin A receptor, type 10.163
Ssbp2single-stranded DNA binding protein 20.162
DaxxFas death domain-associated protein0.161
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.156
Anxa2annexin A20.153
Rassf5Ras association (RalGDS/AF-6) domain family member 50.149
Mpripmyosin phosphatase Rho interacting protein0.149
Chd7chromodomain helicase DNA binding protein 70.147
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.140
Pax2paired box gene 20.140
Vdrvitamin D receptor0.139
Arrb2arrestin, beta 20.136
Capzbcapping protein (actin filament) muscle Z-line, beta0.135
Dll1delta-like 1 (Drosophila)0.134
Mdm4transformed mouse 3T3 cell double minute 40.132
Atf4activating transcription factor 40.130
Notch1Notch gene homolog 1 (Drosophila)0.130
Cdkn1bcyclin-dependent kinase inhibitor 1B0.127
Cd44CD44 antigen0.126
Sfpi1SFFV proviral integration 10.124
Iqcb1IQ calmodulin-binding motif containing 10.122
Ptch1patched homolog 10.121
Mybmyeloblastosis oncogene0.120
Pax6paired box gene 60.119
S100a4S100 calcium binding protein A40.118
Ciccapicua homolog (Drosophila)0.117
Stat2signal transducer and activator of transcription 20.116
Arhgef12Rho guanine nucleotide exchange factor (GEF) 120.115
Socs1suppressor of cytokine signaling 10.114
SrcRous sarcoma oncogene0.110
Rpgrip1lRpgrip1-like0.108
S100a10S100 calcium binding protein A10 (calpactin)0.107
Dennd5aDENN/MADD domain containing 5A0.106
Lgals3lectin, galactose binding, soluble 30.106
Tcf3transcription factor 30.105
Stk4serine/threonine kinase 40.104
Tcf4transcription factor 40.099
Sox11SRY-box containing gene 110.098
Retret proto-oncogene0.096
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.096
Mfn2mitofusin 20.096
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.094
Insm1insulinoma-associated 10.093
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism