The network for 'positive regulation of neurotransmitter secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of neurotransmitter secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.

Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
comtcomatose0.378
Syx1ASyntaxin 1A0.263
laplike-AP1800.234
Snap25Synapse protein 250.204
Nrx-1Neurexin 10.194
dysdysfusion0.194
stnAstoned A0.177
TrpA1Transient receptor potential A10.176
CspCysteine string protein0.137
DabDisabled0.125
brpbruchpilot0.123
elavembryonic lethal abnormal vision0.117
klarklarsicht0.103
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.093
Galpha49BG protein alpha49B0.090
nwknervous wreck0.087
stnBstoned B0.086
eghegghead0.084
GluRIIAGlutamate receptor IIA0.082
VmatVesicular monoamine transporter0.082
par-1CG8201 gene product from transcript CG8201-RA0.077
tipEtemperature-induced paralytic E0.071
G-oalpha47AG protein oalpha 47A0.062
norpAno receptor potential A0.061
hiwhighwire0.059
stjstraightjacket0.058
witwishful thinking0.050
SdcSyndecan0.050
SnapSoluble NSF attachment protein0.048
Syt1Synaptotagmin 10.045
Ank2Ankyrin 20.044
seiseizure0.042
jebjelly belly0.040
Cip4CG15015 gene product from transcript CG15015-RA0.039
neuroliginCG13772 gene product from transcript CG13772-RA0.038
enaenabled0.037
CG32635CG32635 gene product from transcript CG32635-RA0.037
KhcKinesin heavy chain0.033
AdarAdenosine deaminase acting on RNA0.032
unc-104CG8566 gene product from transcript CG8566-RB0.032
RhoGAP92BCG4755 gene product from transcript CG4755-RA0.031
l(2)k16918lethal (2) k169180.031
Ten-mTenascin major0.031
dncdunce0.030
sloslowpoke0.029
CG12187CG12187 gene product from transcript CG12187-RA0.028
fd85Eforkhead domain 85E0.028
n-sybn-synaptobrevin0.027
Vha100-1CG1709 gene product from transcript CG1709-RF0.027
CDaseCeramidase0.027
Dhc64CDynein heavy chain 64C0.026
Gprk1G protein-coupled receptor kinase 10.025
Rac2CG8556 gene product from transcript CG8556-RA0.024
endoAendophilin A0.023
nompCno mechanoreceptor potential C0.023
Frq2Frequenin 20.023
sifstill life0.022
PP2A-B'CG7913 gene product from transcript CG7913-RK0.021
pAbppolyA-binding protein0.021
stmAstambha A0.021
rutrutabaga0.021
Lis-1Lissencephaly-10.019
rostrolling stone0.019
TyrRTyramine receptor0.019
amnamnesiac0.019
aretarrest0.019
rheaCG6831 gene product from transcript CG6831-RA0.019
AtpalphaNa pump alpha subunit0.019
rtGEFrho-type guanine exchange factor0.019
myoglianinCG1838 gene product from transcript CG1838-RD0.018
AceAcetylcholine esterase0.018
DlicDynein light intermediate chain0.018
CaMKIICalcium/calmodulin-dependent protein kinase II0.018
ST6GalSialyltransferase0.018
Frq1Frequenin 10.018
Syn1Syntrophin-like 10.017
eagether a go-go0.017
cpocouch potato0.017
Sema-1aCG18405 gene product from transcript CG18405-RD0.017
VGlutVesicular glutamate transporter0.017
TbhTyramine beta hydroxylase0.017
CG15267CG15267 gene product from transcript CG15267-RA0.017
Vap-33-1CG5014 gene product from transcript CG5014-RB0.017
Rab3Rab-protein 30.016
Syn2Syntrophin-like 20.016
pex1peroxin 10.016
KaiRIACG18039 gene product from transcript CG18039-RA0.015
cpxcomplexin0.015
reporeversed polarity0.015
endoBendophilin B0.015
staistathmin0.015
AlkCG8250 gene product from transcript CG8250-RA0.014
Ggamma1G protein gamma 10.014
CG12424CG12424 gene product from transcript CG12424-RC0.014
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.014
OliOlig family0.014
CG17838CG17838 gene product from transcript CG17838-RA0.014
trptransient receptor potential0.014
eyseyes shut0.013
trpmltransient receptor potential mucolipin0.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.942
Stxbp1syntaxin binding protein 10.729
Apba2amyloid beta (A4) precursor protein-binding, family A, member 20.536
Syn1synapsin I0.521
Vamp2vesicle-associated membrane protein 20.473
Snap25synaptosomal-associated protein 250.420
Rims1regulating synaptic membrane exocytosis 10.367
Drd2dopamine receptor D20.255
Cntn3contactin 3 (plasmacytoma associated)0.226
Cplx1complexin 10.221
Syn2synapsin II0.198
Nfascneurofascin0.179
Nrcamneuronal cell adhesion molecule0.163
Dlgap3discs, large (Drosophila) homolog-associated protein 30.152
Grm7glutamate receptor, metabotropic 70.140
Cnksr2connector enhancer of kinase suppressor of Ras 20.130
Syt1synaptotagmin I0.108
Accn1amiloride-sensitive cation channel 1, neuronal0.092
Nrxn1neurexin 10.085
Hpcal4hippocalcin-like 40.079
Rhbdl1rhomboid, veinlet-like 1 (Drosophila)0.070
Camk1gcalcium/calmodulin-dependent protein kinase IG0.070
Pftk1PFTAIRE protein kinase 10.068
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.067
Gnalguanine nucleotide binding protein, alpha stimulating, olfactory type0.066
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.066
Cacna1gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.066
Drd1adopamine receptor D1A0.064
Ptprn2protein tyrosine phosphatase, receptor type, N polypeptide 20.058
Nlgn1neuroligin 10.056
Dgkbdiacylglycerol kinase, beta0.054
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.051
Myt1lmyelin transcription factor 1-like0.049
Cacnb1calcium channel, voltage-dependent, beta 1 subunit0.048
Slc1a2solute carrier family 1 (glial high affinity glutamate transporter), member 20.048
Syt4synaptotagmin IV0.045
Faim2Fas apoptotic inhibitory molecule 20.041
Dlg2discs, large homolog 2 (Drosophila)0.037
Celsr3cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)0.034
Chrm3cholinergic receptor, muscarinic 30.033
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.032
Nfyanuclear transcription factor-Y alpha0.032
Rab3bRAB3B, member RAS oncogene family0.032
Calb2calbindin 20.031
Hrkharakiri, BCL2 interacting protein (contains only BH3 domain)0.030
Chrm4cholinergic receptor, muscarinic 40.030
Hapln1hyaluronan and proteoglycan link protein 10.030
Gad2glutamate decarboxylase 20.029
Mcf2lMCF.2 cell line derived transforming sequence-like0.029
Map6microtubule-associated protein 60.029
Stx1asyntaxin 1A (brain)0.028
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.027
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.027
Dlgap2discs, large (Drosophila) homolog-associated protein 20.027
Htr45-hydroxytryptamine (serotonin) receptor 40.026
Ascl1achaete-scute complex homolog 1 (Drosophila)0.026
Syt11synaptotagmin XI0.026
Scn2a1sodium channel, voltage-gated, type II, alpha 10.025
Gdf11growth differentiation factor 110.024
Nlgn3neuroligin 30.024
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.024
Slc29a2solute carrier family 29 (nucleoside transporters), member 20.023
Sypsynaptophysin0.022
Scn9asodium channel, voltage-gated, type IX, alpha0.022
Gng7guanine nucleotide binding protein (G protein), gamma 70.022
Gpr12G protein-coupled receptor 120.022
Lphn3latrophilin 30.022
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.021
Htr3a5-hydroxytryptamine (serotonin) receptor 3a0.021
Neurod1neurogenic differentiation 10.021
Slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 10.020
Pacs1phosphofurin acidic cluster sorting protein 10.020
Calcbcalcitonin-related polypeptide, beta0.019
Gabrb2gamma-aminobutyric acid (GABA) A receptor, beta 20.019
Clcn4-2chloride channel 4-20.019
Stxbp5syntaxin binding protein 5 (tomosyn)0.018
Vsnl1visinin-like 10.018
Tacr3tachykinin receptor 30.018
Ptafrplatelet-activating factor receptor0.018
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.018
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.018
Slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.017
Magi1membrane associated guanylate kinase, WW and PDZ domain containing 10.017
Slc24a2solute carrier family 24 (sodium/potassium/calcium exchanger), member 20.017
Cntn1contactin 10.017
Rasgrf1RAS protein-specific guanine nucleotide-releasing factor 10.017
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.016
Glrbglycine receptor, beta0.016
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.015
Ppyr1pancreatic polypeptide receptor 10.015
Abat4-aminobutyrate aminotransferase0.015
Acox3acyl-Coenzyme A oxidase 3, pristanoyl0.014
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.014
Sdc3syndecan 30.014
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.014
Gabbr1gamma-aminobutyric acid (GABA) B receptor 10.014
Gabra4gamma-aminobutyric acid (GABA) A receptor, alpha 40.014
Ptprz1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.014
Gnazguanine nucleotide binding protein (G protein), alpha z polypeptide0.014
Kctd13potassium channel tetramerisation domain containing 130.013
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism