The network for 'compound eye development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

compound eye development

The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.

NameDescriptionProbabilityFunc Analog Organism
E(spl)Enhancer of split0.998
trioCG18214 gene product from transcript CG18214-RA0.991
dosdaughter of sevenless0.985
argosCG4531 gene product from transcript CG4531-RA0.983
sosine oculis0.982
sinaseven in absentia0.977
Rac1CG2248 gene product from transcript CG2248-RA0.970
spensplit ends0.970
cutletCG33122 gene product from transcript CG33122-RA0.970
HLHm7E(spl) region transcript m70.964
hipkhomeodomain interacting protein kinase0.962
TomTwin of m40.961
eyaeyes absent0.960
phlpole hole0.959
Cdc42CG12530 gene product from transcript CG12530-RA0.954
ebiCG4063 gene product from transcript CG4063-RA0.953
PebProtein ejaculatory bulb0.952
VangVan Gogh0.951
Kap-alpha3karyopherin alpha30.936
Akt1CG4006 gene product from transcript CG4006-RA0.930
S6kIIRPS6-protein kinase-II0.921
EgfrEpidermal growth factor receptor0.903
amosabsent MD neurons and olfactory sensilla0.896
Ten-mTenascin major0.896
Rab11Rab-protein 110.894
frcfringe connection0.883
Mi-2CG8103 gene product from transcript CG8103-RA0.865
cindrCIN85 and CD2AP orthologue0.859
Su(Tpl)CG32217 gene product from transcript CG32217-RB0.856
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.854
CG11347CG11347 gene product from transcript CG11347-RE0.840
lqfliquid facets0.828
C3GCG42328 gene product from transcript CG42328-RC0.828
Dsor1Downstream of raf10.825
HLHmdeltaE(spl) region transcript mdelta0.824
emcextra macrochaetae0.823
Gap1GTPase-activating protein 10.815
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.812
opaodd paired0.808
Rme-8Receptor mediated endocytosis 80.793
HopHsp70/Hsp90 organizing protein homolog0.792
X11LCG5675 gene product from transcript CG5675-RB0.790
m4E(spl) region transcript m40.781
Atx-1Ataxin 10.764
ninaEneither inactivation nor afterpotential E0.750
RalaRas-related protein0.750
cicubitus interruptus0.732
RASSF8CG5053 gene product from transcript CG5053-RA0.729
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
otx2orthodenticle homolog 20.905
cdh2cadherin 2, neuronal0.741
her1hairy-related 10.666
pea3ETS-domain transcription factor pea30.578
pax6bpaired box gene 6b0.576
fgf3fibroblast growth factor 30.518
otpborthopedia homolog b0.518
nkx6.2NK6 transcription factor related, locus 20.513
wt1bwilms tumor 1b0.470
irx4biroquois homeobox protein 4b0.447
sox1aSRY-box containing gene 1a0.433
notch1anotch homolog 1a0.402
fgfr4fibroblast growth factor receptor 40.400
socs3asuppressor of cytokine signaling 3a0.366
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.362
wnt5bwingless-type MMTV integration site family, member 5b0.358
nr2e1nuclear receptor subfamily 2, group E, member 10.358
pax8paired box gene 80.353
il7rinterleukin 7 receptor0.350
tfr1atransferrin receptor 1a0.339
pdlim4PDZ and LIM domain 40.339
lrrc50leucine rich repeat containing 500.332
cdx4caudal type homeo box transcription factor 40.328
sox3SRY-box containing gene 30.324
pdlim7PDZ and LIM domain 70.310
insm1binsulinoma-associated 1b0.306
six4bsine oculis homeobox homolog 4b0.304
cbfbcore-binding factor, beta subunit0.301
wnt1wingless-type MMTV integration site family, member 10.299
foxn4forkhead box N40.297
pitx3paired-like homeodomain transcription factor 30.288
wnt2bbwingless-type MMTV integration site family, member 2Bb0.286
sesn1sestrin 10.280
emx1empty spiracles homeobox 10.279
hey1hairy/enhancer-of-split related with YRPW motif 10.275
hmx4H6 family homeobox 40.270
etv2ets variant gene 20.270
gbx2gastrulation brain homeo box 20.263
her8ahairy-related 8a0.263
six4asine oculis homeobox homolog 4a0.262
mespbmesoderm posterior b0.257
dlx4adistal-less homeobox gene 4a0.248
erbb3av-erb-b2 erythroblastic leukemia viral oncogene homolog 3a0.234
wnt11wingless-type MMTV integration site family, member 110.231
rx3retinal homeobox gene 30.231
ndr2nodal-related 20.230
irx3airoquois homeobox protein 3a0.220
six2asine oculis-related homeobox 2a0.216
hoxb1bhomeo box B1b0.216
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.213
foxg1aforkhead box G1a0.211
gli2aGLI-Kruppel family member GLI2a0.211
limk2LIM domain kinase 20.210
gadd45bbgrowth arrest and DNA-damage-inducible, beta b0.208
tmprss4atransmembrane protease, serine 4a0.206
msgn1mesogenin 10.203
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.196
socs3bsuppressor of cytokine signaling 3b0.190
pcdh8protocadherin 80.189
nrg1neuregulin 10.188
ighmimmunoglobulin heavy constant mu and immunoglobulin heavy constant mu0.188
rfx2regulatory factor X, 2 (influences HLA class II expression)0.184
shhbsonic hedgehog b0.181
tbx22T-box 220.181
acsl4aacyl-CoA synthetase long-chain family member 4a0.179
limk1LIM domain kinase 10.177
bmp4bone morphogenetic protein 40.172
hnf1bbHNF1 homeobox Bb0.172
sox19aSRY-box containing gene 19a0.172
chd7chromodomain helicase DNA binding protein 70.171
stap2asignal transducing adaptor family member 2a0.169
rarabretinoic acid receptor, alpha b0.168
spsb4asplA/ryanodine receptor domain and SOCS box containing 4a0.166
olig2oligodendrocyte lineage transcription factor 20.162
card14caspase recruitment domain family, member 140.158
tbr1bT-box, brain, 1b0.157
hlxb9lbhomeo box HB9 like b0.156
flhfloating head0.155
tlx2T-cell leukemia, homeobox 20.153
esyt3extended synaptotagmin-like protein 30.152
tmem88atransmembrane protein 88 a0.150
gyltl1bglycosyltransferase-like 1b0.148
junbljun B proto-oncogene, like0.147
pdlim2PDZ and LIM domain 2 (mystique)0.147
tbx16T-box gene 160.146
her6hairy-related 60.144
jag1ajagged 1a0.144
hhexhematopoietically expressed homeobox0.143
hoxa9ahomeo box A9a0.140
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor0.992
JUNjun proto-oncogene0.962
FUSfused in sarcoma0.940
ATXN1ataxin 10.922
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.913
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.900
NOTCH1notch 10.895
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.892
GRB2growth factor receptor-bound protein 20.882
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.824
CFL1cofilin 1 (non-muscle)0.779
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.776
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.764
RASSF5Ras association (RalGDS/AF-6) domain family member 50.725
AP2B1adaptor-related protein complex 2, beta 1 subunit0.681
LMO4LIM domain only 40.671
ANAPC5anaphase promoting complex subunit 50.637
APPamyloid beta (A4) precursor protein0.615
EGR1early growth response 10.582
NOTCH3notch 30.555
NFYAnuclear transcription factor Y, alpha0.539
RAP1ARAP1A, member of RAS oncogene family0.535
DUSP1dual specificity phosphatase 10.531
ELF4E74-like factor 4 (ets domain transcription factor)0.519
FOSFBJ murine osteosarcoma viral oncogene homolog0.510
BCRbreakpoint cluster region0.508
JAG1jagged 10.476
SOCS3suppressor of cytokine signaling 30.469
AP2M1adaptor-related protein complex 2, mu 1 subunit0.454
NLRC4NLR family, CARD domain containing 40.450
FBXO7F-box protein 70.449
IRF2BP1interferon regulatory factor 2 binding protein 10.440
JUBjub, ajuba homolog (Xenopus laevis)0.422
RIN1Ras and Rab interactor 10.413
ITSN1intersectin 1 (SH3 domain protein)0.406
ATN1atrophin 10.406
WDR5WD repeat domain 50.400
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.389
JUNDjun D proto-oncogene0.361
LIMD1LIM domains containing 10.336
UBA1ubiquitin-like modifier activating enzyme 10.333
CDC27cell division cycle 27 homolog (S. cerevisiae)0.332
BMP1bone morphogenetic protein 10.325
TNRC6Atrinucleotide repeat containing 6A0.323
MAPK8mitogen-activated protein kinase 80.322
RAB14RAB14, member RAS oncogene family0.318
BAIAP2BAI1-associated protein 20.298
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.292
LRDDleucine-rich repeats and death domain containing0.290
GSK3Bglycogen synthase kinase 3 beta0.285
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.281
FOSL1FOS-like antigen 10.277
SMAD1SMAD family member 10.276
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.267
LDOC1leucine zipper, down-regulated in cancer 10.262
CALM1calmodulin 1 (phosphorylase kinase, delta)0.258
MAML1mastermind-like 1 (Drosophila)0.254
ARFIP2ADP-ribosylation factor interacting protein 20.243
FAT1FAT tumor suppressor homolog 1 (Drosophila)0.243
JUNBjun B proto-oncogene0.240
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.231
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.230
CRADDCASP2 and RIPK1 domain containing adaptor with death domain0.229
RIPK2receptor-interacting serine-threonine kinase 20.222
RCHY1ring finger and CHY zinc finger domain containing 10.220
EP300E1A binding protein p3000.217
RUNX1runt-related transcription factor 10.216
SH3KBP1SH3-domain kinase binding protein 10.213
CDC16cell division cycle 16 homolog (S. cerevisiae)0.206
TNRC6Btrinucleotide repeat containing 6B0.205
RBBP5retinoblastoma binding protein 50.197
RLIMring finger protein, LIM domain interacting0.195
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.191
IFNAR2interferon (alpha, beta and omega) receptor 20.185
RAB11FIP1RAB11 family interacting protein 1 (class I)0.183
CDK2cyclin-dependent kinase 20.183
STAT5Asignal transducer and activator of transcription 5A0.180
PGRprogesterone receptor0.175
TSC22D1TSC22 domain family, member 10.168
MMP14matrix metallopeptidase 14 (membrane-inserted)0.167
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.159
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.154
CREBBPCREB binding protein0.153
GMFBglia maturation factor, beta0.152
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.152
NUAK1NUAK family, SNF1-like kinase, 10.150
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.149
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.149
ATF3activating transcription factor 30.148
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.147
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.146
RB1retinoblastoma 10.144
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.141
DCAF7DDB1 and CUL4 associated factor 70.141
PRRC2Cproline-rich coiled-coil 2C0.141
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.140
AIG1androgen-induced 10.138
SOCS1suppressor of cytokine signaling 10.136
TOX4TOX high mobility group box family member 40.133
TAB3TGF-beta activated kinase 1/MAP3K7 binding protein 30.132
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Notch1Notch gene homolog 1 (Drosophila)0.994
Hes1hairy and enhancer of split 1 (Drosophila)0.979
Gli3GLI-Kruppel family member GLI30.936
Dll1delta-like 1 (Drosophila)0.924
Emx1empty spiracles homolog 1 (Drosophila)0.914
Pitx2paired-like homeodomain transcription factor 20.911
Prrx1paired related homeobox 10.904
Shhsonic hedgehog0.879
Foxc1forkhead box C10.877
Casp4caspase 4, apoptosis-related cysteine peptidase0.825
Cdoncell adhesion molecule-related/down-regulated by oncogenes0.804
Eya1eyes absent 1 homolog (Drosophila)0.789
Foxg1forkhead box G10.788
Gli2GLI-Kruppel family member GLI20.746
Tnftumor necrosis factor0.742
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.698
Msx2homeobox, msh-like 20.692
Apcadenomatosis polyposis coli0.684
Hes5hairy and enhancer of split 5 (Drosophila)0.648
Emx2empty spiracles homolog 2 (Drosophila)0.633
Pax2paired box gene 20.625
Fgfr1fibroblast growth factor receptor 10.621
Jag2jagged 20.605
Socs1suppressor of cytokine signaling 10.598
Enahenabled homolog (Drosophila)0.560
Fgf8fibroblast growth factor 80.557
Ric8resistance to inhibitors of cholinesterase 8 homolog (C. elegans)0.554
Cpeb3cytoplasmic polyadenylation element binding protein 30.525
JunJun oncogene0.523
Pax3paired box gene 30.517
Gbp5guanylate binding protein 50.515
Ascl1achaete-scute complex homolog 1 (Drosophila)0.514
Twist2twist homolog 2 (Drosophila)0.512
Psen1presenilin 10.512
Atp11cATPase, class VI, type 11C0.496
Ntf3neurotrophin 30.495
SetSET nuclear oncogene0.493
Gata3GATA binding protein 30.490
Otx2orthodenticle homolog 2 (Drosophila)0.480
Meox2mesenchyme homeobox 20.480
Casp1caspase 10.460
Nucks1nuclear casein kinase and cyclin-dependent kinase substrate 10.446
Ikzf1IKAROS family zinc finger 10.439
Egr2early growth response 20.431
Pbx1pre B-cell leukemia transcription factor 10.428
Gscgoosecoid homeobox0.421
UncxUNC homeobox0.420
Ncoa3nuclear receptor coactivator 30.414
En1engrailed 10.413
PycardPYD and CARD domain containing0.385
Arpc4actin related protein 2/3 complex, subunit 40.371
Apbb1ipamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein0.369
Ptpn11protein tyrosine phosphatase, non-receptor type 110.353
CblCasitas B-lineage lymphoma0.350
Chd7chromodomain helicase DNA binding protein 70.344
Il2rginterleukin 2 receptor, gamma chain0.344
Dlx1distal-less homeobox 10.339
Pip5k1cphosphatidylinositol-4-phosphate 5-kinase, type 1 gamma0.333
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.330
Egr1early growth response 10.321
Hoxa2homeobox A20.310
Hif1ahypoxia inducible factor 1, alpha subunit0.305
Hoxd13homeobox D130.304
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.302
Bocbiregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein0.302
Efsembryonal Fyn-associated substrate0.300
Tcfap2atranscription factor AP-2, alpha0.300
Aim2absent in melanoma 20.294
Rb1retinoblastoma 10.291
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.288
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.278
Tcfap2ctranscription factor AP-2, gamma0.269
Mll1myeloid/lymphoid or mixed-lineage leukemia 10.261
Emid2EMI domain containing 20.258
Egfrepidermal growth factor receptor0.256
Hoxa1homeobox A10.251
Lhx9LIM homeobox protein 90.250
Ptk7PTK7 protein tyrosine kinase 70.248
Ikbkginhibitor of kappaB kinase gamma0.244
Isl1ISL1 transcription factor, LIM/homeodomain0.239
Setdb1SET domain, bifurcated 10.238
Plagl2pleiomorphic adenoma gene-like 20.238
Itgb1integrin beta 1 (fibronectin receptor beta)0.236
Igf2bp2insulin-like growth factor 2 mRNA binding protein 20.236
Foxn1forkhead box N10.235
Hand2heart and neural crest derivatives expressed transcript 20.233
Ptprcprotein tyrosine phosphatase, receptor type, C0.228
Auts2autism susceptibility candidate 20.228
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.228
Hoxa3homeobox A30.226
Sh2b1SH2B adaptor protein 10.222
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.220
Arid1aAT rich interactive domain 1A (SWI-like)0.220
Retret proto-oncogene0.215
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.213
Foxc2forkhead box C20.213
Ikbkbinhibitor of kappaB kinase beta0.206
Dach1dachshund 1 (Drosophila)0.206
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.204
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism