The network for 'positive regulation of chromosome organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of chromosome organization

Any process that activates or increases the frequency, rate or extent of chromosome organization.

NameDescriptionProbabilityFunc Analog Organism
RB1retinoblastoma 10.982
CDC20cell division cycle 20 homolog (S. cerevisiae)0.977
SIN3ASIN3 homolog A, transcription regulator (yeast)0.975
CREBBPCREB binding protein0.963
CBX5chromobox homolog 50.939
CDC27cell division cycle 27 homolog (S. cerevisiae)0.908
TP53tumor protein p530.894
LIN9lin-9 homolog (C. elegans)0.830
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.750
EP300E1A binding protein p3000.723
TERF1telomeric repeat binding factor (NIMA-interacting) 10.692
HIST1H3Bhistone cluster 1, H3b0.661
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.642
BRCA1breast cancer 1, early onset0.638
RBL1retinoblastoma-like 1 (p107)0.588
HDAC1histone deacetylase 10.556
WDR5WD repeat domain 50.539
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.516
UHRF1ubiquitin-like with PHD and ring finger domains 10.481
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.461
PTTG1pituitary tumor-transforming 10.457
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.454
RBBP4retinoblastoma binding protein 40.453
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.407
HCFC1host cell factor C1 (VP16-accessory protein)0.388
NR2E3nuclear receptor subfamily 2, group E, member 30.361
ANAPC4anaphase promoting complex subunit 40.356
HDAC3histone deacetylase 30.353
KDM1Alysine (K)-specific demethylase 1A0.342
EZH2enhancer of zeste homolog 2 (Drosophila)0.341
NRIP1nuclear receptor interacting protein 10.340
NCOA6nuclear receptor coactivator 60.330
IRF2BP1interferon regulatory factor 2 binding protein 10.320
SUZ12suppressor of zeste 12 homolog (Drosophila)0.309
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.301
RBBP5retinoblastoma binding protein 50.287
PMLpromyelocytic leukemia0.272
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.271
TGIF1TGFB-induced factor homeobox 10.264
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.236
CDC23cell division cycle 23 homolog (S. cerevisiae)0.225
CDK2cyclin-dependent kinase 20.224
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.222
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.221
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.214
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.197
SMC6structural maintenance of chromosomes 60.180
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.178
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.178
HIPK2homeodomain interacting protein kinase 20.171
BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)0.167
ANAPC1anaphase promoting complex subunit 10.153
ACDadrenocortical dysplasia homolog (mouse)0.152
ARID1AAT rich interactive domain 1A (SWI-like)0.152
DNMT3ADNA (cytosine-5-)-methyltransferase 3 alpha0.151
EEDembryonic ectoderm development0.151
ANAPC5anaphase promoting complex subunit 50.146
CCNA2cyclin A20.143
SETDB1SET domain, bifurcated 10.138
HIF1ANhypoxia inducible factor 1, alpha subunit inhibitor0.137
MAPK1mitogen-activated protein kinase 10.132
NRP1neuropilin 10.114
TINF2TERF1 (TRF1)-interacting nuclear factor 20.112
CBX3chromobox homolog 30.108
RIF1RAP1 interacting factor homolog (yeast)0.104
STAG1stromal antigen 10.102
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.102
RUNX1runt-related transcription factor 10.100
WDR61WD repeat domain 610.099
TERF2IPtelomeric repeat binding factor 2, interacting protein0.096
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.093
TERF2telomeric repeat binding factor 20.093
H2AFXH2A histone family, member X0.092
POGZpogo transposable element with ZNF domain0.091
PLK1polo-like kinase 10.091
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.090
DUSP1dual specificity phosphatase 10.088
CXXC1CXXC finger protein 10.083
CHAF1Achromatin assembly factor 1, subunit A (p150)0.083
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.083
SUV39H1suppressor of variegation 3-9 homolog 1 (Drosophila)0.082
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.082
BLMBloom syndrome, RecQ helicase-like0.081
HDAC9histone deacetylase 90.081
IKIK cytokine, down-regulator of HLA II0.080
CDAN1congenital dyserythropoietic anemia, type I0.080
WRNWerner syndrome, RecQ helicase-like0.078
CDC26cell division cycle 26 homolog (S. cerevisiae)0.077
VAC14Vac14 homolog (S. cerevisiae)0.075
NSMCE1non-SMC element 1 homolog (S. cerevisiae)0.075
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.075
TSC22D1TSC22 domain family, member 10.075
USP22ubiquitin specific peptidase 220.074
CBFBcore-binding factor, beta subunit0.074
HIST2H3Chistone cluster 2, H3c0.073
RBBP7retinoblastoma binding protein 70.073
SETD8SET domain containing (lysine methyltransferase) 80.071
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
tba-1Protein TBA-10.134
uaf-1Protein UAF-10.105
dsh-2Protein DSH-20.075
unc-14Protein UNC-140.071
B0464.2Protein B0464.20.067
R05F9.9Protein R05F9.90.065
zwl-1Protein ZWL-10.065
hcp-2Protein HCP-20.061
dpl-1Protein DPL-10.059
CELE_F19F10.9Protein F19F10.90.057
T19H12.2Protein T19H12.20.054
ZK507.6Protein ZK507.60.053
rod-1Protein ROD-10.050
hil-2Protein HIL-20.050
cyb-2.2Protein CYB-2.20.048
C16A3.4Protein C16A3.40.045
T08G11.1Protein T08G11.10.044
F08B4.7Protein F08B4.70.044
dcr-1Protein DCR-10.042
him-19Protein HIM-190.041
ubxn-4Protein UBXN-40.041
sdc-1Protein SDC-10.041
F02E8.4Protein F02E8.40.040
F28B3.1Protein F28B3.10.040
hmg-4Protein HMG-40.040
rpn-2Protein RPN-20.040
T09B4.5Protein T09B4.50.039
csn-5Protein CSN-50.039
par-5Protein PAR-50.039
kle-2Protein KLE-20.038
rpb-2Protein RPB-20.037
gla-3Protein GLA-30.037
sdc-3Protein SDC-30.037
trr-1Protein TRR-10.037
prp-8Protein PRP-80.037
Y54E5A.7Protein Y54E5A.70.036
D2030.8Protein D2030.80.036
patr-1Protein PATR-10.036
C49H3.9Protein C49H3.90.035
rpn-1Protein RPN-10.035
mat-3Protein MAT-30.035
F33H1.4Protein F33H1.40.035
cin-4Protein CIN-40.034
F44E2.8Protein F44E2.80.033
Y71G12B.8Protein Y71G12B.80.033
tim-1Protein TIM-10.032
knl-3Protein KNL-30.032
sta-1Protein STA-10.032
CELE_W02A11.1Protein W02A11.10.032
F08B6.1Protein F08B6.10.032
zen-4Protein ZEN-40.032
cey-2Protein CEY-20.031
pyk-2Protein PYK-20.031
mec-15Protein MEC-150.031
zif-1Protein ZIF-10.031
npp-21Protein NPP-210.031
rnp-6Protein RNP-60.030
cyb-2.1Protein CYB-2.10.030
cep-1Protein CEP-10.030
mig-38Protein MIG-380.030
pme-2Protein PME-20.030
rsp-6Protein RSP-60.029
nkcc-1Protein NKCC-10.029
F58G11.3Protein F58G11.30.029
C30A5.3Protein C30A5.30.029
larp-5Protein LARP-50.029
pcn-1Protein PCN-10.029
spr-1Protein SPR-10.029
axl-1Protein AXL-10.029
C14C10.5Protein C14C10.50.029
spd-1Protein SPD-10.029
spt-5Protein SPT-50.029
ubxn-2Protein UBXN-20.029
eif-6Protein EIF-60.029
F18A1.6Protein F18A1.60.028
ndk-1Protein NDK-10.027
gck-1Protein GCK-10.027
cpt-1Protein CPT-10.027
pap-1Protein PAP-10.027
puf-11Protein PUF-110.027
com-1Protein COM-10.027
T18D3.1Protein T18D3.10.027
eor-1Protein EOR-10.027
dnj-30Protein DNJ-300.027
hsp-4Protein HSP-40.027
bath-30Protein BATH-300.027
top-2Protein TOP-20.027
cpg-1Protein CPG-10.026
spr-5Protein SPR-50.026
F09G2.1Protein F09G2.10.026
vps-33.2Protein VPS-33.20.026
nra-3Protein NRA-30.026
tpxl-1Protein TPXL-10.026
hlh-11Protein HLH-110.025
iff-1Protein IFF-10.025
bir-1Protein BIR-10.025
math-33Protein MATH-330.025
cdh-4Protein CDH-40.025
nhr-34Protein NHR-340.025
puf-6Protein PUF-60.025
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
aurkbaurora kinase B0.247
tacc3transforming, acidic coiled-coil containing protein 30.147
bub3BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)0.140
tp53tumor protein p530.118
gdf6agrowth differentiation factor 6a0.111
gata1aGATA binding protein 1a0.104
dnmt3DNA (cytosine-5-)-methyltransferase 30.098
kpna4karyopherin alpha 4 (importin alpha 3)0.091
kif23kinesin family member 230.082
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.079
ahctf1AT hook containing transcription factor 10.079
trpm7transient receptor potential cation channel, subfamily M, member 70.077
kif11kinesin family member 110.071
cse1lchromosome segregation 1-like (S. cerevisiae)0.070
sephs1selenophosphate synthetase 10.069
myst2MYST histone acetyltransferase 20.067
tcea1transcription elongation factor A (SII), 10.066
rif1RAP1 interacting factor homolog (yeast)0.065
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.061
cbx1achromobox homolog 1a (HP1 beta homolog Drosophila)0.060
ntn2netrin 20.058
mapk1mitogen-activated protein kinase 10.057
pnp4apurine nucleoside phosphorylase 4a0.055
rargaretinoic acid receptor gamma a0.051
cx43.4connexin 43.40.050
eya2eyes absent homolog 2 (Drosophila)0.049
cpsf2cleavage and polyadenylation specific factor 20.048
usp1ubiquitin specific protease 10.048
ctnnb1catenin (cadherin-associated protein), beta 10.045
kitakit receptor a0.045
apex1APEX nuclease (multifunctional DNA repair enzyme) 10.045
f2rcoagulation factor II (thrombin) receptor0.045
top2atopoisomerase (DNA) II alpha0.044
myod1myogenic differentiation 10.043
cdc23CDC23 (cell division cycle 23, yeast, homolog)0.043
naspnuclear autoantigenic sperm protein (histone-binding)0.042
melkmaternal embryonic leucine zipper kinase0.042
cstf1cleavage stimulation factor, 3' pre-RNA, subunit 10.041
wlswntless homolog (Drosophila)0.040
foxe3forkhead box E30.039
ercc2excision repair cross-complementing rodent repair deficiency, complementation group 20.039
vsx2visual system homeobox 20.037
tgfbitransforming growth factor, beta-induced0.036
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.036
runx1runt-related transcription factor 10.036
mdm2transformed 3T3 cell double minute 2 homolog (mouse)0.035
pcnaproliferating cell nuclear antigen0.035
ncapgnon-SMC condensin I complex, subunit G0.035
rbm19RNA binding motif protein 190.035
hdac1histone deacetylase 10.035
cep55lcentrosomal protein 55 like0.034
mtmr8myotubularin related protein 80.033
mettl3methyltransferase like 30.033
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.033
kpna3karyopherin (importin) alpha 30.033
hirip3HIRA interacting protein 30.033
gins3GINS complex subunit 30.032
ilf3ainterleukin enhancer binding factor 3a0.032
tfdp1btranscription factor Dp-1, b0.031
stilTAL1 (SCL) interrupting locus0.030
ddx46DEAD (Asp-Glu-Ala-Asp) box polypeptide 460.030
snx27sorting nexin family member 270.029
sp1sp1 transcription factor0.029
kdrlkinase insert domain receptor like0.029
ptpraprotein tyrosine phosphatase, receptor type, A0.029
foxi2forkhead box I20.028
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.028
pbrm1lpolybromo 1, like0.027
ccnb1cyclin B10.027
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae)0.027
dnajc11DnaJ (Hsp40) homolog, subfamily C, member 110.027
vps35vacuolar protein sorting 35 (yeast)0.027
mapk7mitogen-activated protein kinase 70.027
ncapd2non-SMC condensin I complex, subunit D20.027
gins2GINS complex subunit 20.026
fzd2frizzled homolog 20.026
pold1polymerase (DNA directed), delta 1, catalytic subunit0.026
lppLIM domain containing preferred translocation partner in lipoma0.026
rcn3reticulocalbin 3, EF-hand calcium binding domain0.026
ncaphnon-SMC condensin I complex, subunit H0.026
plk1polo-like kinase 1 (Drosophila)0.026
leo1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.026
copacoatomer protein complex, subunit alpha0.025
znf703zinc finger protein 7030.025
kif14kinesin family member 140.025
kirrelbkin of IRRE like b0.025
arpp19acAMP-regulated phosphoprotein 19a0.025
gro1groucho 10.025
msi1musashi homolog 1 (Drosophila)0.025
hs3st3b1bheparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b0.025
hspa4bheat shock protein 4b0.025
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.999
Suz12suppressor of zeste 12 homolog (Drosophila)0.931
Eedembryonic ectoderm development0.790
Ptenphosphatase and tensin homolog0.741
Ezh2enhancer of zeste homolog 2 (Drosophila)0.728
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.631
Tgfb1transforming growth factor, beta 10.548
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.492
Trim24tripartite motif-containing 240.384
Kdm2blysine (K)-specific demethylase 2B0.369
Arid1aAT rich interactive domain 1A (SWI-like)0.345
Jarid2jumonji, AT rich interactive domain 20.318
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.296
Ghrgrowth hormone receptor0.277
Kdm1alysine (K)-specific demethylase 1A0.276
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.272
Cdkn1bcyclin-dependent kinase inhibitor 1B0.254
Cdk1cyclin-dependent kinase 10.238
Smc1astructural maintenance of chromosomes 1A0.231
JunJun oncogene0.218
Trim28tripartite motif-containing 280.214
Akt1thymoma viral proto-oncogene 10.207
Smc3structural maintenace of chromosomes 30.198
Runx1runt related transcription factor 10.194
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.188
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.179
Tnftumor necrosis factor0.178
Mtf2metal response element binding transcription factor 20.167
Ppargperoxisome proliferator activated receptor gamma0.164
Ptgs2prostaglandin-endoperoxide synthase 20.164
Apcadenomatosis polyposis coli0.159
Pds5bPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.158
Dnmt3aDNA methyltransferase 3A0.157
Ube2cubiquitin-conjugating enzyme E2C0.155
Col1a1collagen, type I, alpha 10.150
Foxp1forkhead box P10.146
Gata1GATA binding protein 10.146
Thoc2THO complex 20.144
Acdadrenocortical dysplasia0.144
CrebbpCREB binding protein0.144
Nos2nitric oxide synthase 2, inducible0.140
Hist1h3ghistone cluster 1, H3g0.131
Rararetinoic acid receptor, alpha0.127
Mdm2transformed mouse 3T3 cell double minute 20.127
Stip1stress-induced phosphoprotein 10.126
Arrb2arrestin, beta 20.126
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.125
Msh2mutS homolog 2 (E. coli)0.124
Rb1retinoblastoma 10.122
Ash1lash1 (absent, small, or homeotic)-like (Drosophila)0.121
Cdkn2acyclin-dependent kinase inhibitor 2A0.117
Hdac1histone deacetylase 10.117
Cav1caveolin 1, caveolae protein0.109
Nos3nitric oxide synthase 3, endothelial cell0.107
Tnrc6btrinucleotide repeat containing 6b0.106
Zeb1zinc finger E-box binding homeobox 10.106
Mecp2methyl CpG binding protein 20.099
Bod1lbiorientation of chromosomes in cell division 1-like0.098
Ep300E1A binding protein p3000.096
E2f1E2F transcription factor 10.094
Rbbp4retinoblastoma binding protein 40.092
Stat3signal transducer and activator of transcription 30.089
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.086
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.086
Trp63transformation related protein 630.085
Kitlkit ligand0.085
Arid2AT rich interactive domain 2 (ARID, RFX-like)0.084
Ccna2cyclin A20.082
Tcf3transcription factor 30.082
Atmataxia telangiectasia mutated homolog (human)0.082
Hprthypoxanthine guanine phosphoribosyl transferase0.082
Parp1poly (ADP-ribose) polymerase family, member 10.081
Sin3atranscriptional regulator, SIN3A (yeast)0.080
Ccnb2cyclin B20.080
Egr1early growth response 10.078
Plin1perilipin 10.078
Cct7chaperonin containing Tcp1, subunit 7 (eta)0.077
Sf3b1splicing factor 3b, subunit 10.076
Axin1axin 10.071
Ccnfcyclin F0.070
Brd4bromodomain containing 40.069
Lmnalamin A0.068
Csf1colony stimulating factor 1 (macrophage)0.068
Plk1polo-like kinase 1 (Drosophila)0.068
Trp73transformation related protein 730.068
Thrathyroid hormone receptor alpha0.067
Brca1breast cancer 10.067
Zfp292zinc finger protein 2920.066
Mybl2myeloblastosis oncogene-like 20.066
Lmnb1lamin B10.066
Huwe1HECT, UBA and WWE domain containing 10.064
Smad3MAD homolog 3 (Drosophila)0.063
Gli2GLI-Kruppel family member GLI20.063
Mapk1mitogen-activated protein kinase 10.062
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.060
Mdm4transformed mouse 3T3 cell double minute 40.060
Vdrvitamin D receptor0.060
Cdk4cyclin-dependent kinase 40.060
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hspa8heat shock protein 80.016
Stip1stress-induced phosphoprotein 10.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
YNL155Whypothetical protein0.011