The network for 'regulation of synaptic transmission dopaminergic' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of synaptic transmission dopaminergic

Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.

NameDescriptionProbabilityFunc Analog Organism
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.976
ADORA2Aadenosine A2a receptor0.965
TOR1AIP2torsin A interacting protein 20.929
COPS4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)0.824
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.811
TOR1Atorsin family 1, member A (torsin A)0.799
ARRB1arrestin, beta 10.634
FBXO7F-box protein 70.611
TOR1Btorsin family 1, member B (torsin B)0.581
CFL1cofilin 1 (non-muscle)0.558
RAB5CRAB5C, member RAS oncogene family0.543
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.454
MAST1microtubule associated serine/threonine kinase 10.267
SNCAIPsynuclein, alpha interacting protein0.264
TPPPtubulin polymerization promoting protein0.208
MAPTmicrotubule-associated protein tau0.186
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.137
IL1Binterleukin 1, beta0.127
CXCL3chemokine (C-X-C motif) ligand 30.116
CNIH4cornichon homolog 4 (Drosophila)0.114
APLP1amyloid beta (A4) precursor-like protein 10.097
IL8interleukin 80.073
MAP2K4mitogen-activated protein kinase kinase 40.067
LRRK2leucine-rich repeat kinase 20.061
HIST2H2ABhistone cluster 2, H2ab0.055
PDE4Dphosphodiesterase 4D, cAMP-specific0.053
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.052
CHRNA4cholinergic receptor, nicotinic, alpha 40.049
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.048
MAP3K1mitogen-activated protein kinase kinase kinase 10.044
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.044
ADRA1Badrenergic, alpha-1B-, receptor0.038
RIMS1regulating synaptic membrane exocytosis 10.036
TOR1AIP1torsin A interacting protein 10.035
DOCK7dedicator of cytokinesis 70.034
SMN1survival of motor neuron 1, telomeric0.033
NAMPTnicotinamide phosphoribosyltransferase0.033
SPTBN1spectrin, beta, non-erythrocytic 10.033
APPamyloid beta (A4) precursor protein0.032
MAPK10mitogen-activated protein kinase 100.032
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.031
CXCL2chemokine (C-X-C motif) ligand 20.030
MED8mediator complex subunit 80.030
CLTAclathrin, light chain A0.028
RIMS2regulating synaptic membrane exocytosis 20.026
DUSP3dual specificity phosphatase 30.026
MAPK3mitogen-activated protein kinase 30.025
LBX1ladybird homeobox 10.025
GORABgolgin, RAB6-interacting0.024
DUSP1dual specificity phosphatase 10.024
BRSK2BR serine/threonine kinase 20.024
MARK1MAP/microtubule affinity-regulating kinase 10.023
RPH3Arabphilin 3A homolog (mouse)0.023
FABP4fatty acid binding protein 4, adipocyte0.022
PDE4DIPphosphodiesterase 4D interacting protein0.022
NCS1neuronal calcium sensor 10.021
AP2A1adaptor-related protein complex 2, alpha 1 subunit0.021
LIMK1LIM domain kinase 10.020
TOR3Atorsin family 3, member A0.020
FEZF2FEZ family zinc finger 20.020
NECAB2N-terminal EF-hand calcium binding protein 20.019
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.019
KCNT1potassium channel, subfamily T, member 10.019
AP1M2adaptor-related protein complex 1, mu 2 subunit0.019
PTAFRplatelet-activating factor receptor0.019
ENGendoglin0.018
FOSFBJ murine osteosarcoma viral oncogene homolog0.018
HAGHhydroxyacylglutathione hydrolase0.018
DYNC1H1dynein, cytoplasmic 1, heavy chain 10.018
PICK1protein interacting with PRKCA 10.018
PPM1Dprotein phosphatase, Mg2+/Mn2+ dependent, 1D0.018
RGS2regulator of G-protein signaling 2, 24kDa0.018
CNTFRciliary neurotrophic factor receptor0.017
BGLAPbone gamma-carboxyglutamate (gla) protein0.017
SDC3syndecan 30.017
HCN2hyperpolarization activated cyclic nucleotide-gated potassium channel 20.017
TNFAIP6tumor necrosis factor, alpha-induced protein 60.017
RASSF5Ras association (RalGDS/AF-6) domain family member 50.016
MAST3microtubule associated serine/threonine kinase 30.016
ADORA1adenosine A1 receptor0.016
DHCR77-dehydrocholesterol reductase0.016
MBIPMAP3K12 binding inhibitory protein 10.016
S100A2S100 calcium binding protein A20.016
HIPK3homeodomain interacting protein kinase 30.016
HRH3histamine receptor H30.016
GNAZguanine nucleotide binding protein (G protein), alpha z polypeptide0.016
ARHGDIGRho GDP dissociation inhibitor (GDI) gamma0.016
EEF1A2eukaryotic translation elongation factor 1 alpha 20.016
GFRA2GDNF family receptor alpha 20.016
S100BS100 calcium binding protein B0.015
ZNF746zinc finger protein 7460.015
PCSK1Nproprotein convertase subtilisin/kexin type 1 inhibitor0.015
RABAC1Rab acceptor 1 (prenylated)0.015
CHRNB2cholinergic receptor, nicotinic, beta 2 (neuronal)0.015
NOVA2neuro-oncological ventral antigen 20.015
MAPK14mitogen-activated protein kinase 140.015
A1BGalpha-1-B glycoprotein0.015
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.015
APBA1amyloid beta (A4) precursor protein-binding, family A, member 10.014
FGF8fibroblast growth factor 8 (androgen-induced)0.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
unc-29Protein UNC-290.277
lev-8Protein LEV-80.179
cls-1Protein CLS-10.061
rig-6Protein RIG-60.048
glr-5Protein GLR-50.041
tmc-2Protein TMC-20.039
acr-8Protein ACR-80.035
prl-1Protein PRL-10.034
dmsr-1Protein DMSR-10.034
F52D10.6Protein F52D10.60.029
ZC449.5Protein ZC449.50.027
F40A3.4Protein F40A3.40.026
C49A9.3Protein C49A9.30.023
lgc-39Protein LGC-390.023
unc-47Protein UNC-470.021
fmo-1Protein FMO-10.020
unc-38Protein UNC-380.020
oig-4Protein OIG-40.020
unc-105Protein UNC-1050.019
dmsr-7Protein DMSR-70.019
lev-1Protein LEV-10.018
inx-6Protein INX-60.018
pdfr-1Protein PDFR-10.017
frm-3Protein FRM-30.017
hpo-28Protein HPO-280.016
unc-10Protein UNC-100.016
tph-1Protein TPH-10.015
CELE_K09H11.1Protein K09H11.10.015
unc-7Protein UNC-70.014
sel-7Protein SEL-70.014
F46G11.1Protein F46G11.10.014
R08E3.1Protein R08E3.10.013
cpna-1Protein CPNA-10.013
oct-2Protein OCT-20.013
ser-2Protein SER-20.013
ncx-2Protein NCX-20.013
cka-2Protein CKA-20.013
rol-3Protein ROL-30.013
ceh-24Protein CEH-240.013
abu-7Protein ABU-70.013
F55B11.1Protein F55B11.10.013
sto-5Protein STO-50.011
clec-243Protein CLEC-2430.011
acr-15Protein ACR-150.011
best-23Protein BEST-230.010
gar-3Protein GAR-30.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.860
Chrnb2cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)0.701
Chrnb4cholinergic receptor, nicotinic, beta polypeptide 40.575
Chrna3cholinergic receptor, nicotinic, alpha polypeptide 30.452
Arrb1arrestin, beta 10.225
Nos1nitric oxide synthase 1, neuronal0.182
Arrb2arrestin, beta 20.131
Cd151CD151 antigen0.049
Dccdeleted in colorectal carcinoma0.046
Otx2orthodenticle homolog 2 (Drosophila)0.046
Itgb1integrin beta 1 (fibronectin receptor beta)0.045
Chrna10cholinergic receptor, nicotinic, alpha polypeptide 100.031
Lhx3LIM homeobox protein 30.024
Chrna6cholinergic receptor, nicotinic, alpha polypeptide 60.024
Nxnl2nucleoredoxin-like 20.023
Rhorhodopsin0.021
Lpar5lysophosphatidic acid receptor 50.021
Cckbrcholecystokinin B receptor0.020
Pgrprogesterone receptor0.020
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.019
Scgnsecretagogin, EF-hand calcium binding protein0.018
Slc12a1solute carrier family 12, member 10.015
Mab21l2mab-21-like 2 (C. elegans)0.014
Dcxdoublecortin0.013
Rit2Ras-like without CAAX 20.013
Oprm1opioid receptor, mu 10.013
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.013
Stk32bserine/threonine kinase 32B0.013
Acheacetylcholinesterase0.012
Kcnq2potassium voltage-gated channel, subfamily Q, member 20.012
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.011
Ntn1netrin 10.011
Glra1glycine receptor, alpha 1 subunit0.011
Pde6bphosphodiesterase 6B, cGMP, rod receptor, beta polypeptide0.011
Hcn3hyperpolarization-activated, cyclic nucleotide-gated K+ 30.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Trhr2thyrotropin releasing hormone receptor 20.021
Nxph1neurexophilin 10.018
Thtyrosine hydroxylase0.018
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.014
Khkketohexokinase0.013
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.013
Sdc3syndecan 30.012
Magmyelin-associated glycoprotein0.011
Pde1bphosphodiesterase 1B, calmodulin-dependent0.011
Csdc2cold shock domain containing C2, RNA binding0.011
Eporerythropoietin receptor0.011
Ascl1achaete-scute complex homolog 1 (Drosophila)0.010
Grik1glutamate receptor, ionotropic, kainate 10.010
Folh1folate hydrolase 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism