The network for 'proline transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

proline transport

The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

NameDescriptionProbabilityFunc Analog Organism
PICK1protein interacting with PRKCA 10.904
DRD2dopamine receptor D20.849
SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 10.504
SLC7A5solute carrier family 7 (cationic amino acid transporter, y+ system), member 50.332
AARSalanyl-tRNA synthetase0.310
SLC3A2solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 20.287
GARSglycyl-tRNA synthetase0.253
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.181
YARStyrosyl-tRNA synthetase0.175
MARSmethionyl-tRNA synthetase0.139
TPPPtubulin polymerization promoting protein0.117
USP50ubiquitin specific peptidase 500.078
TRIB3tribbles homolog 3 (Drosophila)0.071
EIF4EBP1eukaryotic translation initiation factor 4E binding protein 10.068
PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.066
MPDU1mannose-P-dolichol utilization defect 10.064
CARScysteinyl-tRNA synthetase0.056
STX1Asyntaxin 1A (brain)0.054
SHMT2serine hydroxymethyltransferase 2 (mitochondrial)0.042
PRLHRprolactin releasing hormone receptor0.039
HYOU1hypoxia up-regulated 10.039
ASNSasparagine synthetase (glutamine-hydrolyzing)0.039
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.039
PHGDHphosphoglycerate dehydrogenase0.036
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.034
ADORA2Aadenosine A2a receptor0.033
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.032
NEK6NIMA (never in mitosis gene a)-related kinase 60.032
SARSseryl-tRNA synthetase0.030
PRODH2proline dehydrogenase (oxidase) 20.029
PSAT1phosphoserine aminotransferase 10.025
HMGA1high mobility group AT-hook 10.024
PYCR1pyrroline-5-carboxylate reductase 10.024
SLC6A12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 120.023
SLC22A6solute carrier family 22 (organic anion transporter), member 60.023
PAX8paired box 80.022
SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 30.021
MUC3Amucin 3A, cell surface associated0.021
TM4SF5transmembrane 4 L six family member 50.017
CHAC1ChaC, cation transport regulator homolog 1 (E. coli)0.017
SLC5A1solute carrier family 5 (sodium/glucose cotransporter), member 10.016
SLC17A1solute carrier family 17 (sodium phosphate), member 10.016
SLC34A1solute carrier family 34 (sodium phosphate), member 10.016
TUBtubby homolog (mouse)0.016
CYP17A1cytochrome P450, family 17, subfamily A, polypeptide 10.016
HCRTR1hypocretin (orexin) receptor 10.015
SLC2A1solute carrier family 2 (facilitated glucose transporter), member 10.015
SLC6A9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.015
EMX1empty spiracles homeobox 10.014
LTKleukocyte receptor tyrosine kinase0.014
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 50.014
SLC17A7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.013
SLC7A11solute carrier family 7, (cationic amino acid transporter, y+ system) member 110.013
GRM2glutamate receptor, metabotropic 20.013
SPTBspectrin, beta, erythrocytic0.013
SLC7A4solute carrier family 7 (cationic amino acid transporter, y+ system), member 40.013
SIX6SIX homeobox 60.013
UNC93Aunc-93 homolog A (C. elegans)0.013
SLC1A6solute carrier family 1 (high affinity aspartate/glutamate transporter), member 60.013
IRX4iroquois homeobox 40.012
RHOrhodopsin0.012
SLC13A2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 20.012
MAGmyelin associated glycoprotein0.012
HNF1BHNF1 homeobox B0.012
SHHsonic hedgehog0.012
TMEM151Atransmembrane protein 151A0.012
GNG13guanine nucleotide binding protein (G protein), gamma 130.012
POU4F2POU class 4 homeobox 20.012
SLC13A3solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 30.012
CBScystathionine-beta-synthase0.011
RBP2retinol binding protein 2, cellular0.011
CYP11B2cytochrome P450, family 11, subfamily B, polypeptide 20.011
VEGFAvascular endothelial growth factor A0.011
CEBPGCCAAT/enhancer binding protein (C/EBP), gamma0.011
HSF1heat shock transcription factor 10.011
CNTN2contactin 2 (axonal)0.011
HTR2C5-hydroxytryptamine (serotonin) receptor 2C0.011
KLK6kallikrein-related peptidase 60.011
MLXIPLMLX interacting protein-like0.011
GRINAglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.011
GJC2gap junction protein, gamma 2, 47kDa0.011
MYO16myosin XVI0.011
PDZK1IP1PDZK1 interacting protein 10.011
XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound0.010
EGR4early growth response 40.010
UNC5Bunc-5 homolog B (C. elegans)0.010
BEAN1brain expressed, associated with NEDD4, 10.010
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 20.010
CHP2calcineurin B homologous protein 20.010
AGXTalanine-glyoxylate aminotransferase0.010
KCNC3potassium voltage-gated channel, Shaw-related subfamily, member 30.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc34a1solute carrier family 34 (sodium phosphate), member 10.031
Cubncubilin (intrinsic factor-cobalamin receptor)0.028
Mep1ameprin 1 alpha0.028
Slc22a6solute carrier family 22 (organic anion transporter), member 60.027
Lrp2low density lipoprotein receptor-related protein 20.022
Slc17a1solute carrier family 17 (sodium phosphate), member 10.022
Akr1c21aldo-keto reductase family 1, member C210.022
Slc22a2solute carrier family 22 (organic cation transporter), member 20.021
Slc7a9solute carrier family 7 (cationic amino acid transporter, y+ system), member 90.018
Dync1i1dynein cytoplasmic 1 intermediate chain 10.017
Slc12a1solute carrier family 12, member 10.017
Clcnkachloride channel Ka0.015
DaoD-amino acid oxidase0.013
Ltkleukocyte tyrosine kinase0.012
Slc5a11solute carrier family 5 (sodium/glucose cotransporter), member 110.012
Slc6a18solute carrier family 6 (neurotransmitter transporter), member 180.011
Crymcrystallin, mu0.011
Tff1trefoil factor 10.011
Ngefneuronal guanine nucleotide exchange factor0.011
Spns3spinster homolog 3 (Drosophila)0.011
Scg5secretogranin V0.010
Folr1folate receptor 1 (adult)0.010
2410004A20RikRIKEN cDNA 2410004A20 gene0.010
Syn2synapsin II0.010
Pdzd3PDZ domain containing 30.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Rac2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.034
LOC689399hypothetical protein LOC6893990.030
Ly86lymphocyte antigen 860.024
Fcer1gFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.019
TyrobpTyro protein tyrosine kinase binding protein0.018
Pgam2phosphoglycerate mutase 2 (muscle)0.016
Smcpsperm mitochondria-associated cysteine-rich protein0.016
Rpl8ribosomal protein L80.016
PycardPYD and CARD domain containing0.015
Asb9ankyrin repeat and SOCS box-containing 90.014
Slc6a2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.014
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.013
Slc6a17solute carrier family 6 (neurotransmitter transporter), member 170.013
Akt2v-akt murine thymoma viral oncogene homolog 20.013
LOC171573spleen protein 1 precursor0.013
Rps15ribosomal protein S150.013
Laptm5lysosomal protein transmembrane 50.013
Gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2 like 10.013
C5ar1complement component 5a receptor 10.013
Tlr7toll-like receptor 70.013
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.013
Col4a1collagen, type IV, alpha 10.013
Rpl28ribosomal protein L280.012
Tlx3T-cell leukemia, homeobox 30.012
Il9rinterleukin 9 receptor0.012
Gpnmbglycoprotein (transmembrane) nmb0.012
Arpc1bactin related protein 2/3 complex, subunit 1B0.012
Fam65afamily with sequence similarity 65, member A0.012
C1qacomplement component 1, q subcomponent, A chain0.012
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.011
Cd53Cd53 molecule0.011
Arntaryl hydrocarbon receptor nuclear translocator0.011
LOC499782similar to 60S ribosomal protein L120.011
Ms4a6bmembrane-spanning 4-domains, subfamily A, member 6B0.011
RGD1309139similar to CG5435-PA0.011
Psg29pregnancy-specific glycoprotein 290.011
Racgap1Rac GTPase-activating protein 10.011
Metmet proto-oncogene0.011
Lcp1lymphocyte cytosolic protein 10.011
Fxyd5FXYD domain-containing ion transport regulator 50.011
Ttll3tubulin tyrosine ligase-like family, member 30.010
Tpm4tropomyosin 40.010
Ptprcprotein tyrosine phosphatase, receptor type, C0.010
Ceacam11carcinoembryonic antigen-related cell adhesion molecule 110.010
Plekpleckstrin0.010
Cd37CD37 molecule0.010
Icosinducible T-cell co-stimulator0.010
Flnafilamin A, alpha0.010
Phexphosphate regulating endopeptidase homolog, X-linked0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism