The network for 'cloacal septation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cloacal septation

The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development.

NameDescriptionProbabilityFunc Analog Organism
KRT5keratin 51.000
CABLES1Cdk5 and Abl enzyme substrate 10.982
SATB2SATB homeobox 20.967
FGF18fibroblast growth factor 180.911
KRT6Ckeratin 6C0.819
ZFYVE9zinc finger, FYVE domain containing 90.812
WNT1wingless-type MMTV integration site family, member 10.407
S1PR5sphingosine-1-phosphate receptor 50.377
WIF1WNT inhibitory factor 10.343
MMP11matrix metallopeptidase 11 (stromelysin 3)0.219
HNRNPCL1heterogeneous nuclear ribonucleoprotein C-like 10.198
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.192
TNK1tyrosine kinase, non-receptor, 10.185
SFRP1secreted frizzled-related protein 10.157
NPAS1neuronal PAS domain protein 10.135
IHHIndian hedgehog0.130
WNT3wingless-type MMTV integration site family, member 30.119
WNT10Awingless-type MMTV integration site family, member 10A0.113
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.104
POU3F1POU class 3 homeobox 10.093
FGF3fibroblast growth factor 30.090
NIPSNAP3Anipsnap homolog 3A (C. elegans)0.084
HPXhemopexin0.068
BMPR1Abone morphogenetic protein receptor, type IA0.065
GUCA2Aguanylate cyclase activator 2A (guanylin)0.060
BMP8Abone morphogenetic protein 8a0.060
HS3ST6heparan sulfate (glucosamine) 3-O-sulfotransferase 60.059
HES2hairy and enhancer of split 2 (Drosophila)0.058
WNT4wingless-type MMTV integration site family, member 40.055
LY6Dlymphocyte antigen 6 complex, locus D0.055
UACAuveal autoantigen with coiled-coil domains and ankyrin repeats0.055
DAPK2death-associated protein kinase 20.054
BMP2bone morphogenetic protein 20.053
FGF4fibroblast growth factor 40.052
FOXF2forkhead box F20.052
ZNF676zinc finger protein 6760.048
ENTPD2ectonucleoside triphosphate diphosphohydrolase 20.048
SHHsonic hedgehog0.047
BMP4bone morphogenetic protein 40.047
HMX1H6 family homeobox 10.046
WNT11wingless-type MMTV integration site family, member 110.042
PTPN14protein tyrosine phosphatase, non-receptor type 140.042
COL4A6collagen, type IV, alpha 60.042
PAX8paired box 80.041
AQP5aquaporin 50.040
KRT6Akeratin 6A0.040
FZD10frizzled homolog 10 (Drosophila)0.039
LBX1ladybird homeobox 10.039
CYP11B2cytochrome P450, family 11, subfamily B, polypeptide 20.038
FSTL1follistatin-like 10.038
HOXA11homeobox A110.037
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.037
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.036
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.036
TLX3T-cell leukemia homeobox 30.034
NKD1naked cuticle homolog 1 (Drosophila)0.034
EPHB2EPH receptor B20.034
P2RX2purinergic receptor P2X, ligand-gated ion channel, 20.033
PAX3paired box 30.033
FOXE1forkhead box E1 (thyroid transcription factor 2)0.033
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.033
NKD2naked cuticle homolog 2 (Drosophila)0.033
NEUROG2neurogenin 20.032
WNT7Awingless-type MMTV integration site family, member 7A0.032
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 50.031
HOXD13homeobox D130.031
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.031
SPIBSpi-B transcription factor (Spi-1/PU.1 related)0.030
LHX6LIM homeobox 60.030
LMX1ALIM homeobox transcription factor 1, alpha0.030
HSD11B2hydroxysteroid (11-beta) dehydrogenase 20.030
SLC29A4solute carrier family 29 (nucleoside transporters), member 40.030
BNC1basonuclin 10.030
SOX21SRY (sex determining region Y)-box 210.030
HOXC8homeobox C80.029
LYPD3LY6/PLAUR domain containing 30.029
FGD1FYVE, RhoGEF and PH domain containing 10.028
ACANaggrecan0.028
EFNA3ephrin-A30.027
GSTM4glutathione S-transferase mu 40.027
GDNFglial cell derived neurotrophic factor0.026
HOXD10homeobox D100.026
CRLF1cytokine receptor-like factor 10.025
CTF1cardiotrophin 10.025
WNT10Bwingless-type MMTV integration site family, member 10B0.025
EPHB3EPH receptor B30.024
PRRX2paired related homeobox 20.024
ROR2receptor tyrosine kinase-like orphan receptor 20.023
HOXB13homeobox B130.023
BMP7bone morphogenetic protein 70.023
SMOsmoothened homolog (Drosophila)0.023
PRSS53protease, serine, 530.022
DUOX1dual oxidase 10.022
IRX4iroquois homeobox 40.022
GPR3G protein-coupled receptor 30.022
EVPLenvoplakin0.022
EXOC3L2exocyst complex component 3-like 20.022
WNT7Bwingless-type MMTV integration site family, member 7B0.021
HOXD11homeobox D110.021
SIX2SIX homeobox 20.021
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog0.999
Fgfr2fibroblast growth factor receptor 20.999
Sox9SRY-box containing gene 90.981
Gli3GLI-Kruppel family member GLI30.968
Foxc1forkhead box C10.897
Ctnnb1catenin (cadherin associated protein), beta 10.890
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.884
Ptenphosphatase and tensin homolog0.879
Rspo2R-spondin 2 homolog (Xenopus laevis)0.773
Pax3paired box gene 30.752
Tgfb2transforming growth factor, beta 20.682
Prrx1paired related homeobox 10.680
Apcadenomatosis polyposis coli0.651
Trp63transformation related protein 630.648
Bmp7bone morphogenetic protein 70.558
Smosmoothened homolog (Drosophila)0.522
Dlx5distal-less homeobox 50.502
Fgfr1fibroblast growth factor receptor 10.502
Msx1homeobox, msh-like 10.451
Foxc2forkhead box C20.400
Gli2GLI-Kruppel family member GLI20.336
Rararetinoic acid receptor, alpha0.317
Fgfr3fibroblast growth factor receptor 30.308
Bmp4bone morphogenetic protein 40.308
Tcfap2atranscription factor AP-2, alpha0.305
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.294
Chrdchordin0.279
Ptch1patched homolog 10.257
Tbx1T-box 10.253
Nodalnodal0.233
Rarbretinoic acid receptor, beta0.224
Col1a1collagen, type I, alpha 10.224
Fgf8fibroblast growth factor 80.181
Rxraretinoid X receptor alpha0.180
Eya1eyes absent 1 homolog (Drosophila)0.132
Ror2receptor tyrosine kinase-like orphan receptor 20.130
Otx2orthodenticle homolog 2 (Drosophila)0.126
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.120
Prrx2paired related homeobox 20.117
Hand2heart and neural crest derivatives expressed transcript 20.115
Hand1heart and neural crest derivatives expressed transcript 10.109
Zeb1zinc finger E-box binding homeobox 10.108
Meox2mesenchyme homeobox 20.104
Cdkn2acyclin-dependent kinase inhibitor 2A0.098
Pax6paired box gene 60.095
Msx2homeobox, msh-like 20.092
Fgf10fibroblast growth factor 100.092
Ptpn11protein tyrosine phosphatase, non-receptor type 110.083
Vegfavascular endothelial growth factor A0.081
Wnt3awingless-related MMTV integration site 3A0.058
Mdm2transformed mouse 3T3 cell double minute 20.052
Alx4aristaless-like homeobox 40.050
Pitx2paired-like homeodomain transcription factor 20.048
Tgfbr2transforming growth factor, beta receptor II0.048
Nognoggin0.046
Trp73transformation related protein 730.045
Itgb1integrin beta 1 (fibronectin receptor beta)0.042
Rargretinoic acid receptor, gamma0.042
Runx2runt related transcription factor 20.040
Acvr1activin A receptor, type 10.040
Lrp6low density lipoprotein receptor-related protein 60.038
Rb1retinoblastoma 10.038
Ednraendothelin receptor type A0.035
Sfnstratifin0.034
Psen1presenilin 10.034
Esr1estrogen receptor 1 (alpha)0.034
Nf1neurofibromatosis 10.033
Trp53transformation related protein 530.032
Gja1gap junction protein, alpha 10.032
Mdm4transformed mouse 3T3 cell double minute 40.031
Alx1ALX homeobox 10.030
Zic3zinc finger protein of the cerebellum 30.028
Tcof1Treacher Collins Franceschetti syndrome 1, homolog0.027
Vangl2vang-like 2 (van gogh, Drosophila)0.025
Egfrepidermal growth factor receptor0.025
Yap1yes-associated protein 10.024
Ece1endothelin converting enzyme 10.024
Gscgoosecoid homeobox0.023
Pbx1pre B-cell leukemia transcription factor 10.022
Cdx2caudal type homeobox 20.021
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.019
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.019
Smad3MAD homolog 3 (Drosophila)0.019
BmperBMP-binding endothelial regulator0.019
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.019
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.019
Pax9paired box gene 90.018
Lef1lymphoid enhancer binding factor 10.018
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.015
Sox4SRY-box containing gene 40.015
BrafBraf transforming gene0.014
Hrhairless0.014
Foxh1forkhead box H10.013
Pthlhparathyroid hormone-like peptide0.013
Dlx6distal-less homeobox 60.013
Sox2SRY-box containing gene 20.013
Kitkit oncogene0.013
Emx2empty spiracles homolog 2 (Drosophila)0.012
Emx1empty spiracles homolog 1 (Drosophila)0.012
Smn1survival motor neuron 10.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism