The network for 'erythrocyte development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

erythrocyte development

The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
TAL1T-cell acute lymphocytic leukemia 10.997
HBBhemoglobin, beta0.812
HBG2hemoglobin, gamma G0.758
GATA1GATA binding protein 1 (globin transcription factor 1)0.716
GATA2GATA binding protein 20.691
SPTBspectrin, beta, erythrocytic0.616
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.599
ANK1ankyrin 1, erythrocytic0.551
RBBP5retinoblastoma binding protein 50.433
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.367
PTPN1protein tyrosine phosphatase, non-receptor type 10.349
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.346
FBXO7F-box protein 70.331
NCOR2nuclear receptor corepressor 20.328
WDR5WD repeat domain 50.327
RPL39ribosomal protein L390.300
SLC4A1solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)0.264
RHAGRh-associated glycoprotein0.244
HSPB1heat shock 27kDa protein 10.237
PRPF38APRP38 pre-mRNA processing factor 38 (yeast) domain containing A0.229
RPS27ribosomal protein S270.212
RPS14ribosomal protein S140.208
ZCCHC17zinc finger, CCHC domain containing 170.184
RPS13ribosomal protein S130.171
HCFC1host cell factor C1 (VP16-accessory protein)0.171
RPS18ribosomal protein S180.163
RUNX1runt-related transcription factor 10.162
RPLP2ribosomal protein, large, P20.158
MKL1megakaryoblastic leukemia (translocation) 10.152
AFF1AF4/FMR2 family, member 10.144
TGS1trimethylguanosine synthase 10.141
RHDRh blood group, D antigen0.140
GYPBglycophorin B (MNS blood group)0.133
SIN3ASIN3 homolog A, transcription regulator (yeast)0.131
INSRinsulin receptor0.128
GAS7growth arrest-specific 70.119
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.115
CCNT1cyclin T10.112
CDK9cyclin-dependent kinase 90.106
RPS11ribosomal protein S110.106
MYL4myosin, light chain 4, alkali; atrial, embryonic0.105
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.100
KLF13Kruppel-like factor 130.098
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.095
STAP2signal transducing adaptor family member 20.093
MYOD1myogenic differentiation 10.093
MED13mediator complex subunit 130.092
RPS28ribosomal protein S280.090
ALAS2aminolevulinate, delta-, synthase 20.090
RHCERh blood group, CcEe antigens0.089
HCFC2host cell factor C20.085
SPTA1spectrin, alpha, erythrocytic 1 (elliptocytosis 2)0.084
CDK19cyclin-dependent kinase 190.083
NCOA1nuclear receptor coactivator 10.081
PCDH9protocadherin 90.080
BRD4bromodomain containing 40.078
SKIv-ski sarcoma viral oncogene homolog (avian)0.077
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.074
RPS15ribosomal protein S150.073
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.073
AFF4AF4/FMR2 family, member 40.069
HBDhemoglobin, delta0.067
TCF12transcription factor 120.064
HBE1hemoglobin, epsilon 10.062
PF4platelet factor 40.062
ARID4BAT rich interactive domain 4B (RBP1-like)0.059
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.053
MYST1MYST histone acetyltransferase 10.053
KLF1Kruppel-like factor 1 (erythroid)0.052
HBZhemoglobin, zeta0.051
CEBPDCCAAT/enhancer binding protein (C/EBP), delta0.050
OSBP2oxysterol binding protein 20.049
SMURF1SMAD specific E3 ubiquitin protein ligase 10.047
EPB42erythrocyte membrane protein band 4.20.047
TBX5T-box 50.045
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.043
HDAC5histone deacetylase 50.043
MYOGmyogenin (myogenic factor 4)0.042
CREBBPCREB binding protein0.042
RARAretinoic acid receptor, alpha0.041
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.040
ABI1abl-interactor 10.040
IL2RBinterleukin 2 receptor, beta0.040
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.039
CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 30.039
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.037
MEN1multiple endocrine neoplasia I0.037
EP300E1A binding protein p3000.036
TRIM10tripartite motif containing 100.035
JAK1Janus kinase 10.034
KELKell blood group, metallo-endopeptidase0.034
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.033
LYL1lymphoblastic leukemia derived sequence 10.033
CCNL1cyclin L10.033
RPS19ribosomal protein S190.032
MKL2MKL/myocardin-like 20.032
JAK2Janus kinase 20.031
TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.031
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.031
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
alas2aminolevulinate, delta-, synthetase 20.990
gata1aGATA binding protein 1a0.987
slc4a1asolute carrier family 4, anion exchanger, member 1a0.762
epb41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)0.745
tal1T-cell acute lymphocytic leukemia 10.615
lmo2LIM domain only 2 (rhombotin-like 1)0.575
hbbe3hemoglobin beta embryonic-30.475
hbbe2hemoglobin beta embryonic-20.467
klf4Kruppel-like factor 40.457
hbae3hemoglobin alpha embryonic-30.400
hhexhematopoietically expressed homeobox0.369
cmybtranscription factor cmyb0.319
ptf1apancreas specific transcription factor, 1a0.301
sptbspectrin, beta, erythrocytic0.279
gata4GATA-binding protein 40.248
klfdKruppel-like factor d0.242
tfr1atransferrin receptor 1a0.238
hdrhematopoietic death receptor0.218
ikzf1IKAROS family zinc finger 1 (Ikaros)0.213
znfl2azinc finger-like gene 2a0.213
LOC566708FL cytokine receptor-like0.165
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.163
adnp2bADNP homeobox 2b0.138
hbae1hemoglobin alpha embryonic-10.128
rpl11ribosomal protein L110.127
hbbe1.1hemoglobin beta embryonic-1.10.124
gata6GATA-binding protein 60.123
nt5c2l15'-nucleotidase, cytosolic II, like 10.121
cahzcarbonic anhydrase0.118
urosuroporphyrinogen III synthase0.107
rpl9ribosomal protein L90.102
fgf8bfibroblast growth factor 8 b0.101
foxi1forkhead box I10.100
mpxmyeloid-specific peroxidase0.096
gad2glutamate decarboxylase 20.092
atoh1batonal homolog 1b0.088
rbbp6retinoblastoma binding protein 60.087
cpoxcoproporphyrinogen oxidase0.079
cx30.3connexin 30.30.065
adora2aaadenosine A2a receptor a0.064
mstnbmyostatin b0.064
trim33tripartite motif-containing 330.063
tbx5aT-box 5a0.063
ppoxprotoporphyrinogen oxidase0.063
trpv6transient receptor potential cation channel, subfamily V, member 60.062
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.061
pax2apaired box gene 2a0.059
nadkaNAD kinase a0.059
uroduroporphyrinogen decarboxylase0.057
rpl23aribosomal protein L23a0.055
ppdpfapancreatic progenitor cell differentiation and proliferation factor a0.053
eporerythropoietin receptor0.050
eya2eyes absent homolog 2 (Drosophila)0.049
vhlvon Hippel-Lindau tumor suppressor0.047
rpl13aribosomal protein L13a0.045
mta3metastasis associated family, member 30.043
sirt1sirtuin (silent mating type information regulation 2 homolog) 10.042
atoh1aatonal homolog 1a0.041
aplnrbapelin receptor b0.041
eef1b2eukaryotic translation elongation factor 1 beta 20.041
rpl36aribosomal protein L36A0.041
spns2spinster homolog 2 (Drosophila)0.040
fgf10afibroblast growth factor 10a0.039
trim71tripartite motif-containing 710.039
rps15ribosomal protein S150.039
pitx2paired-like homeodomain transcription factor 20.039
lhx1bLIM homeobox 1b0.038
chrna2acholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)0.037
tbx24T-box 240.037
ppp4r2bprotein phosphatase 4, regulatory subunit 2b0.037
sec13SEC13 homolog (S. cerevisiae)0.037
jak2aJanus kinase 2a0.036
efnb1ephrin B10.036
LOC10000099960S ribosomal protein L37-like0.036
slc25a25asolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a0.035
elk4ELK4, ETS-domain protein0.035
nr2f5nuclear receptor subfamily 2, group F, member 50.035
tnnc1atroponin C type 1a (slow)0.035
hmbsbhydroxymethylbilane synthase, b0.034
wnt2bbwingless-type MMTV integration site family, member 2Bb0.034
nkx2.5NK2 transcription factor related 50.034
nfe2nuclear factor, erythroid-derived 20.034
tp63tumor protein p630.034
per3period homolog 3 (Drosophila)0.033
foxn4forkhead box N40.033
gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 10.032
fem1cfem-1 homolog c (C.elegans)0.032
bmi1B lymphoma Mo-MLV insertion region 10.031
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Atp5hATP synthase, H+ transporting, mitochondrial F0 complex, subunit d0.012
LOC688869similar to cytochrome c oxidase, subunit VIb polypeptide 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism