The network for 'anterior posterior axis specification embryo' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

anterior posterior axis specification embryo

The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.

NameDescriptionProbabilityFunc Analog Organism
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.995
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.994
EIF4A3eukaryotic translation initiation factor 4A30.990
OCRLoculocerebrorenal syndrome of Lowe0.975
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.966
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.923
SNAP25synaptosomal-associated protein, 25kDa0.918
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.878
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.848
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.837
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.832
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.826
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.825
CLNS1Achloride channel, nucleotide-sensitive, 1A0.813
SCHIP1schwannomin interacting protein 10.787
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.752
PRMT5protein arginine methyltransferase 50.711
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.697
GDAguanine deaminase0.692
HNRNPMheterogeneous nuclear ribonucleoprotein M0.680
CDC27cell division cycle 27 homolog (S. cerevisiae)0.672
RBL2retinoblastoma-like 2 (p130)0.661
PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.613
PRKCZprotein kinase C, zeta0.602
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.577
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.574
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.564
KEAP1kelch-like ECH-associated protein 10.541
NXF1nuclear RNA export factor 10.510
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.495
LIN9lin-9 homolog (C. elegans)0.477
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.472
RFWD2ring finger and WD repeat domain 20.463
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.457
PRKCIprotein kinase C, iota0.441
UPF1UPF1 regulator of nonsense transcripts homolog (yeast)0.425
APCadenomatous polyposis coli0.415
ADAM17ADAM metallopeptidase domain 170.410
NFE2L2nuclear factor (erythroid-derived 2)-like 20.408
CDK9cyclin-dependent kinase 90.406
CUL2cullin 20.403
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.394
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.386
CUL1cullin 10.380
BMP1bone morphogenetic protein 10.374
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.369
SORBS3sorbin and SH3 domain containing 30.362
BRAFv-raf murine sarcoma viral oncogene homolog B10.361
DLG4discs, large homolog 4 (Drosophila)0.337
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.336
MAPK1mitogen-activated protein kinase 10.335
MDC1mediator of DNA-damage checkpoint 10.312
CD44CD44 molecule (Indian blood group)0.309
STRADASTE20-related kinase adaptor alpha0.296
EDC3enhancer of mRNA decapping 3 homolog (S. cerevisiae)0.296
ANAPC7anaphase promoting complex subunit 70.294
SRSF2serine/arginine-rich splicing factor 20.287
KIF5Bkinesin family member 5B0.282
SETSET nuclear oncogene0.282
SNRPGsmall nuclear ribonucleoprotein polypeptide G0.270
HSPA8heat shock 70kDa protein 80.260
FGFR1fibroblast growth factor receptor 10.255
CAB39calcium binding protein 390.254
CDC16cell division cycle 16 homolog (S. cerevisiae)0.253
YAP1Yes-associated protein 10.248
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.245
SRRM1serine/arginine repetitive matrix 10.243
RBX1ring-box 1, E3 ubiquitin protein ligase0.243
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.241
AKIP1A kinase (PRKA) interacting protein 10.239
PBKPDZ binding kinase0.236
DCAF7DDB1 and CUL4 associated factor 70.235
LARP1La ribonucleoprotein domain family, member 10.218
MYH9myosin, heavy chain 9, non-muscle0.216
U2AF1U2 small nuclear RNA auxiliary factor 10.216
JMJD6jumonji domain containing 60.215
HNRNPA1heterogeneous nuclear ribonucleoprotein A10.215
SDSLserine dehydratase-like0.215
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.213
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.212
VHLvon Hippel-Lindau tumor suppressor0.212
AKAP11A kinase (PRKA) anchor protein 110.207
FBF1Fas (TNFRSF6) binding factor 10.205
MAP2K1mitogen-activated protein kinase kinase 10.202
ACTN1actinin, alpha 10.198
SH3RF3SH3 domain containing ring finger 30.197
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.188
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.186
EIF4G1eukaryotic translation initiation factor 4 gamma, 10.185
GAB1GRB2-associated binding protein 10.184
SNRPD1small nuclear ribonucleoprotein D1 polypeptide 16kDa0.184
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.179
RHOAras homolog gene family, member A0.178
WNT3Awingless-type MMTV integration site family, member 3A0.175
COBRA1cofactor of BRCA10.175
RAB11FIP1RAB11 family interacting protein 1 (class I)0.170
CHN2chimerin (chimaerin) 20.168
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nanos3nanos homolog 30.566
piwil1piwi-like 1 (Drosophila)0.512
ca15bcarbonic anhydrase XV b0.396
ndr2nodal-related 20.343
tbx16T-box gene 160.221
aplnrbapelin receptor b0.180
brca2breast cancer 2, early onset0.077
orgoogenesis-related gene0.058
pou5f1POU domain, class 5, transcription factor 10.054
dazldaz-like gene0.053
acvr1lactivin A receptor, type I like0.042
piwil2piwi-like 2 (Drosophila)0.040
flhfloating head0.039
cdx4caudal type homeo box transcription factor 40.037
etv2ets variant gene 20.037
sox32SRY-box containing gene 320.035
ntlano tail a0.034
dlg2discs, large (Drosophila) homolog 20.034
runx1runt-related transcription factor 10.034
bmp4bone morphogenetic protein 40.032
spsb4asplA/ryanodine receptor domain and SOCS box containing 4a0.032
wnt2bbwingless-type MMTV integration site family, member 2Bb0.029
tmem2transmembrane protein 20.026
znf711zinc finger protein 7110.024
cdh2cadherin 2, neuronal0.024
pnxposterior neuron-specific homeobox0.023
epb4.1l4erythrocyte protein band 4.1-like 40.023
pglyrp2peptidoglycan recognition protein 20.023
klf4Kruppel-like factor 40.023
mibmind bomb0.023
bmp7abone morphogenetic protein 7a0.022
hand2heart and neural crest derivatives expressed transcript 20.022
sap18sin3-associated polypeptide0.020
fanclFanconi anemia, complementation group L0.019
foxh1forkhead box H10.019
smosmoothened homolog (Drosophila)0.018
dlg1discs, large (Drosophila) homolog 10.018
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.018
six4bsine oculis homeobox homolog 4b0.018
tdrd1tudor domain containing 10.017
wnt11wingless-type MMTV integration site family, member 110.017
csrp1acysteine and glycine-rich protein 1a0.017
pcdh8protocadherin 80.016
tbx1T-box 10.015
gfi1.1growth factor independent 1.10.015
brd4bromodomain containing 40.014
ventventral expressed homeobox0.014
tbx20T-box 200.014
tmem88atransmembrane protein 88 a0.014
spsb1splA/ryanodine receptor domain and SOCS box containing 10.014
smad5MAD homolog 5 (Drosophila)0.012
bucbucky ball0.012
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.012
copebcore promoter element binding protein0.012
col8a1acollagen, type VIII, alpha 1a0.011
fli1bfriend leukemia integration 1b0.011
arnt2aryl hydrocarbon receptor nuclear translocator 20.011
eif5aeukaryotic translation initiation factor 5A0.011
gpiaglucose phosphate isomerase a0.011
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.011
nog1noggin 10.011
gdf9growth differentiation factor 90.011
ilkintegrin linked kinase0.011
pfn2profilin 20.011
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.010
vangl2vang-like 2 (van gogh, Drosophila)0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
aPKCatypical protein kinase C0.991
bratbrain tumor0.965
traltrailer hitch0.959
magomago nashi0.958
par-1CG8201 gene product from transcript CG8201-RA0.934
Src64BSrc oncogene at 64B0.918
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.909
par-6CG5884 gene product from transcript CG5884-RA0.889
BicDBicaudal D0.868
ksrkinase suppressor of ras0.780
Cdc42CG12530 gene product from transcript CG12530-RA0.734
CG6854CG6854 gene product from transcript CG6854-RC0.712
lolalongitudinals lacking0.707
pitaCG3941 gene product from transcript CG3941-RA0.680
spn-Espindle E0.680
fs(1)M3female sterile (1) M30.629
Dcp1Decapping protein 10.619
orboo18 RNA-binding protein0.614
Dhc64CDynein heavy chain 64C0.598
spensplit ends0.563
ftz-f1ftz transcription factor 10.547
Gprk2G protein-coupled receptor kinase 20.540
Myd88CG2078 gene product from transcript CG2078-RA0.519
EcREcdysone receptor0.518
sec5CG8843 gene product from transcript CG8843-RA0.506
me31Bmaternal expression at 31B0.498
TER94CG2331 gene product from transcript CG2331-RA0.472
CG10260CG10260 gene product from transcript CG10260-RB0.456
DlicDynein light intermediate chain0.430
eyaeyes absent0.425
Hel25EHelicase at 25E0.419
CG4771CG4771 gene product from transcript CG4771-RA0.397
Grip128CG9201 gene product from transcript CG9201-RB0.392
slmbsupernumerary limbs0.386
DadDaughters against dpp0.383
Pabp2CG2163 gene product from transcript CG2163-RA0.342
ovoCG6824 gene product from transcript CG6824-RE0.334
fkhfork head0.329
CG11188CG11188 gene product from transcript CG11188-RA0.312
Btk29ABtk family kinase at 29A0.305
Fmr1CG6203 gene product from transcript CG6203-RC0.284
cpacapping protein alpha0.282
Rac1CG2248 gene product from transcript CG2248-RA0.263
dallydivision abnormally delayed0.254
LanALaminin A0.248
UBL3CG9038 gene product from transcript CG9038-RC0.244
tho2CG31671 gene product from transcript CG31671-RA0.229
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.220
gcmglial cells missing0.216
rawCG12437 gene product from transcript CG12437-RB0.216
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.982
Shhsonic hedgehog0.899
Fgf8fibroblast growth factor 80.871
Lhx1LIM homeobox protein 10.863
Pitx2paired-like homeodomain transcription factor 20.722
Apcadenomatosis polyposis coli0.687
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.671
Bmpr1abone morphogenetic protein receptor, type 1A0.602
Sox9SRY-box containing gene 90.585
Otx2orthodenticle homolog 2 (Drosophila)0.516
Gata4GATA binding protein 40.503
Pax2paired box gene 20.455
Fgfr1fibroblast growth factor receptor 10.455
Fgfr2fibroblast growth factor receptor 20.393
Rarbretinoic acid receptor, beta0.385
Rxraretinoid X receptor alpha0.375
Rararetinoic acid receptor, alpha0.372
Wnt4wingless-related MMTV integration site 40.352
Tbx1T-box 10.344
Rargretinoic acid receptor, gamma0.330
Gli2GLI-Kruppel family member GLI20.273
Gli3GLI-Kruppel family member GLI30.270
Smad4MAD homolog 4 (Drosophila)0.265
Foxc1forkhead box C10.262
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.243
Ece1endothelin converting enzyme 10.229
Inpp5dinositol polyphosphate-5-phosphatase D0.217
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.216
Foxh1forkhead box H10.207
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.204
Stx1asyntaxin 1A (brain)0.175
Gsk3bglycogen synthase kinase 3 beta0.172
Wnt6wingless-related MMTV integration site 60.160
Snap25synaptosomal-associated protein 250.160
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.159
Emx2empty spiracles homolog 2 (Drosophila)0.153
Fusfusion, derived from t(12;16) malignant liposarcoma (human)0.150
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.148
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.136
Pitx1paired-like homeodomain transcription factor 10.132
Hand2heart and neural crest derivatives expressed transcript 20.120
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.119
Vaspvasodilator-stimulated phosphoprotein0.118
Pum1pumilio 1 (Drosophila)0.117
Dlx5distal-less homeobox 50.111
Arid1bAT rich interactive domain 1B (SWI-like)0.107
Arandrogen receptor0.105
Wt1Wilms tumor 1 homolog0.102
Msx1homeobox, msh-like 10.101
Hand1heart and neural crest derivatives expressed transcript 10.100
Fzd7frizzled homolog 7 (Drosophila)0.095
Dok2docking protein 20.093
Prrx2paired related homeobox 20.088
Smosmoothened homolog (Drosophila)0.084
Smad1MAD homolog 1 (Drosophila)0.084
Hoxa2homeobox A20.083
Smad3MAD homolog 3 (Drosophila)0.083
Cct2chaperonin containing Tcp1, subunit 2 (beta)0.082
Bmp4bone morphogenetic protein 40.071
Acvr1activin A receptor, type 10.070
Nf1neurofibromatosis 10.065
Itgb1integrin beta 1 (fibronectin receptor beta)0.064
Nr5a1nuclear receptor subfamily 5, group A, member 10.062
Amhr2anti-Mullerian hormone type 2 receptor0.058
Lhx9LIM homeobox protein 90.057
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.057
Fzd8frizzled homolog 8 (Drosophila)0.055
Bmp7bone morphogenetic protein 70.054
Gdf1growth differentiation factor 10.053
Ccnd1cyclin D10.053
Fzd1frizzled homolog 1 (Drosophila)0.051
Hoxa1homeobox A10.051
Alx4aristaless-like homeobox 40.050
Numbnumb gene homolog (Drosophila)0.049
Retret proto-oncogene0.047
Msx2homeobox, msh-like 20.047
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.046
Bicd2bicaudal D homolog 2 (Drosophila)0.045
Magohmago-nashi homolog, proliferation-associated (Drosophila)0.044
Fgf10fibroblast growth factor 100.043
SrcRous sarcoma oncogene0.042
Emx1empty spiracles homolog 1 (Drosophila)0.039
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.039
Trp53transformation related protein 530.038
Ttc7tetratricopeptide repeat domain 70.038
Hic1hypermethylated in cancer 10.038
Arid1aAT rich interactive domain 1A (SWI-like)0.037
Gata6GATA binding protein 60.037
Wnt9awingless-type MMTV integration site 9A0.036
Dkk1dickkopf homolog 1 (Xenopus laevis)0.036
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.036
Twist2twist homolog 2 (Drosophila)0.035
Ncoa2nuclear receptor coactivator 20.035
Erhenhancer of rudimentary homolog (Drosophila)0.035
Vegfavascular endothelial growth factor A0.034
Gdnfglial cell line derived neurotrophic factor0.034
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism