The network for 'positive regulation of cardioblast differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cardioblast differentiation

Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.

NameDescriptionProbabilityFunc Analog Organism
TBX5T-box 51.000
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)1.000
TGFBR2transforming growth factor, beta receptor II (70/80kDa)1.000
FSTL1follistatin-like 11.000
TGFBR1transforming growth factor, beta receptor 10.991
GATA4GATA binding protein 40.989
TGFB3transforming growth factor, beta 30.969
KLF13Kruppel-like factor 130.906
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.671
GATA5GATA binding protein 50.534
DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila)0.498
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.448
BMP2bone morphogenetic protein 20.313
NRP1neuropilin 10.295
ACVR2Bactivin A receptor, type IIB0.243
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 10.220
APPamyloid beta (A4) precursor protein0.212
TGFBR3transforming growth factor, beta receptor III0.209
PYYpeptide YY0.204
MYH6myosin, heavy chain 6, cardiac muscle, alpha0.197
HOXD12homeobox D120.197
NR5A1nuclear receptor subfamily 5, group A, member 10.154
KIR3DL2killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 20.152
LBX1ladybird homeobox 10.151
PAX9paired box 90.134
HAND2heart and neural crest derivatives expressed 20.110
SIX2SIX homeobox 20.104
HOXD9homeobox D90.100
NEUROG2neurogenin 20.087
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.083
APBA1amyloid beta (A4) precursor protein-binding, family A, member 10.079
SOX1SRY (sex determining region Y)-box 10.076
COL2A1collagen, type II, alpha 10.075
FOXE1forkhead box E1 (thyroid transcription factor 2)0.073
TBX20T-box 200.069
DLX4distal-less homeobox 40.069
TGFB2transforming growth factor, beta 20.068
SMAD7SMAD family member 70.067
HOXC11homeobox C110.066
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.064
FGF3fibroblast growth factor 30.062
FOXF1forkhead box F10.058
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.058
FOXN4forkhead box N40.056
HOXB13homeobox B130.051
BHLHE23basic helix-loop-helix family, member e230.050
PTPN14protein tyrosine phosphatase, non-receptor type 140.049
TBX2T-box 20.048
FOXL1forkhead box L10.047
CXCR6chemokine (C-X-C motif) receptor 60.046
FKBP1AFK506 binding protein 1A, 12kDa0.046
HOXA3homeobox A30.046
BDNFbrain-derived neurotrophic factor0.044
HOXD11homeobox D110.044
CDX2caudal type homeobox 20.043
GATA3GATA binding protein 30.042
HES2hairy and enhancer of split 2 (Drosophila)0.042
SIX6SIX homeobox 60.041
ALX4ALX homeobox 40.040
HOXA11homeobox A110.040
SIM2single-minded homolog 2 (Drosophila)0.039
FOXA2forkhead box A20.039
HOXB5homeobox B50.039
NKX3-2NK3 homeobox 20.039
SFRP5secreted frizzled-related protein 50.038
DHHdesert hedgehog0.038
OTPorthopedia homeobox0.037
CAMTA2calmodulin binding transcription activator 20.036
TGFB1transforming growth factor, beta 10.035
SLC6A4solute carrier family 6 (neurotransmitter transporter, serotonin), member 40.035
PTPN21protein tyrosine phosphatase, non-receptor type 210.034
MESP1mesoderm posterior 1 homolog (mouse)0.033
GCM2glial cells missing homolog 2 (Drosophila)0.033
HOXB9homeobox B90.033
TBX1T-box 10.032
LTKleukocyte receptor tyrosine kinase0.031
PRDM13PR domain containing 130.031
PAX5paired box 50.031
HNF1BHNF1 homeobox B0.030
CALCAcalcitonin-related polypeptide alpha0.030
TLX1T-cell leukemia homeobox 10.030
TCF15transcription factor 15 (basic helix-loop-helix)0.030
PRF1perforin 1 (pore forming protein)0.030
SOX18SRY (sex determining region Y)-box 180.029
PHOX2Apaired-like homeobox 2a0.029
HBE1hemoglobin, epsilon 10.029
IRX5iroquois homeobox 50.029
KLHL35kelch-like 35 (Drosophila)0.029
FOXC1forkhead box C10.028
HOXC8homeobox C80.028
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.027
HOXC12homeobox C120.027
FGF8fibroblast growth factor 8 (androgen-induced)0.027
PITX2paired-like homeodomain 20.027
SIX3SIX homeobox 30.027
HNF1AHNF1 homeobox A0.027
HOXD3homeobox D30.027
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)1.000
Hand2heart and neural crest derivatives expressed transcript 21.000
Gata4GATA binding protein 41.000
Shhsonic hedgehog1.000
Hand1heart and neural crest derivatives expressed transcript 11.000
Gata6GATA binding protein 60.999
Fgf8fibroblast growth factor 80.999
Fgfr2fibroblast growth factor receptor 20.999
Pitx2paired-like homeodomain transcription factor 20.998
Sox9SRY-box containing gene 90.997
Bmp4bone morphogenetic protein 40.996
Rxraretinoid X receptor alpha0.983
Mesp1mesoderm posterior 10.982
Foxc2forkhead box C20.980
Tbx1T-box 10.979
Ptpn11protein tyrosine phosphatase, non-receptor type 110.968
Tbx3T-box 30.968
Foxc1forkhead box C10.967
Msx1homeobox, msh-like 10.961
Pax3paired box gene 30.950
Jag1jagged 10.943
Zfpm2zinc finger protein, multitype 20.938
Gja5gap junction protein, alpha 50.933
Ntf3neurotrophin 30.927
Scn5asodium channel, voltage-gated, type V, alpha0.926
Vegfavascular endothelial growth factor A0.921
Gli2GLI-Kruppel family member GLI20.885
Prrx1paired related homeobox 10.848
Pitx1paired-like homeodomain transcription factor 10.830
Tbx5T-box 50.829
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.785
Gli3GLI-Kruppel family member GLI30.774
Hey2hairy/enhancer-of-split related with YRPW motif 20.763
Tcfap2atranscription factor AP-2, alpha0.745
Isl1ISL1 transcription factor, LIM/homeodomain0.715
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.629
Nos3nitric oxide synthase 3, endothelial cell0.625
Acvr1activin A receptor, type 10.621
Runx2runt related transcription factor 20.618
Hoxa1homeobox A10.555
Rarbretinoic acid receptor, beta0.532
Efnb2ephrin B20.525
Gja1gap junction protein, alpha 10.511
Col2a1collagen, type II, alpha 10.473
Ror2receptor tyrosine kinase-like orphan receptor 20.433
Gata5GATA binding protein 50.414
Msx2homeobox, msh-like 20.406
Gscgoosecoid homeobox0.402
Fgfr3fibroblast growth factor receptor 30.381
Fgf10fibroblast growth factor 100.367
Egfrepidermal growth factor receptor0.357
Tgfbr2transforming growth factor, beta receptor II0.345
Smosmoothened homolog (Drosophila)0.344
Hoxa13homeobox A130.342
Nkx2-6NK2 transcription factor related, locus 6 (Drosophila)0.336
Zeb1zinc finger E-box binding homeobox 10.331
Alx4aristaless-like homeobox 40.330
Tgfb2transforming growth factor, beta 20.326
Prrx2paired related homeobox 20.318
Sox4SRY-box containing gene 40.307
Bmp7bone morphogenetic protein 70.305
Foxf1aforkhead box F1a0.297
Bmpr1abone morphogenetic protein receptor, type 1A0.285
Klf3Kruppel-like factor 3 (basic)0.284
Meox2mesenchyme homeobox 20.277
Bmp2bone morphogenetic protein 20.274
Otporthopedia homolog (Drosophila)0.261
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.260
Twist2twist homolog 2 (Drosophila)0.237
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.237
Wnt3awingless-related MMTV integration site 3A0.236
Hoxd13homeobox D130.219
Alx3aristaless-like homeobox 30.217
Pax9paired box gene 90.206
Fgf3fibroblast growth factor 30.198
Tcf21transcription factor 210.188
Ighmbp2immunoglobulin mu binding protein 20.188
Dlx5distal-less homeobox 50.184
Col1a1collagen, type I, alpha 10.183
Lmx1bLIM homeobox transcription factor 1 beta0.182
Pthlhparathyroid hormone-like peptide0.179
Nkx6-1NK6 homeobox 10.174
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.162
Eya1eyes absent 1 homolog (Drosophila)0.141
Fgfr1fibroblast growth factor receptor 10.139
Tlx2T-cell leukemia, homeobox 20.138
Wnt6wingless-related MMTV integration site 60.136
Ednraendothelin receptor type A0.130
Adam17a disintegrin and metallopeptidase domain 170.129
Pitx3paired-like homeodomain transcription factor 30.123
Pcdh12protocadherin 120.121
Rararetinoic acid receptor, alpha0.116
Gpc3glypican 30.115
Barx1BarH-like homeobox 10.105
Lhx3LIM homeobox protein 30.105
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.101
Nkx3-2NK3 homeobox 20.099
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.094
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism