The network for 'ribosomal large subunit biogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ribosomal large subunit biogenesis

A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.

NameDescriptionProbabilityFunc Analog Organism
LYARLy1 antibody reactive homolog (mouse)0.990
GNL3guanine nucleotide binding protein-like 3 (nucleolar)0.957
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.893
BOP1block of proliferation 10.694
SENP3SUMO1/sentrin/SMT3 specific peptidase 30.685
GTPBP4GTP binding protein 40.669
GNL2guanine nucleotide binding protein-like 2 (nucleolar)0.665
RPL17ribosomal protein L170.593
PELP1proline, glutamate and leucine rich protein 10.450
MYBBP1AMYB binding protein (P160) 1a0.369
PUS1pseudouridylate synthase 10.348
RBM28RNA binding motif protein 280.300
PES1pescadillo homolog 1, containing BRCT domain (zebrafish)0.296
RPL27Aribosomal protein L27a0.274
RPL3ribosomal protein L30.263
MDM2Mdm2 p53 binding protein homolog (mouse)0.236
NOP56NOP56 ribonucleoprotein homolog (yeast)0.195
BTF3basic transcription factor 30.186
RPL4ribosomal protein L40.185
RPL18ribosomal protein L180.180
DNTTIP2deoxynucleotidyltransferase, terminal, interacting protein 20.178
RPL7Aribosomal protein L7a0.175
CEBPZCCAAT/enhancer binding protein (C/EBP), zeta0.169
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.169
RPL31ribosomal protein L310.158
DKC1dyskeratosis congenita 1, dyskerin0.155
EBNA1BP2EBNA1 binding protein 20.146
ZC3H15zinc finger CCCH-type containing 150.141
DDX21DEAD (Asp-Glu-Ala-Asp) box polypeptide 210.132
RPL29ribosomal protein L290.128
RPF2ribosome production factor 2 homolog (S. cerevisiae)0.127
BRIX1BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)0.124
RPL6ribosomal protein L60.119
EEF1B2eukaryotic translation elongation factor 1 beta 20.108
MPHOSPH10M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)0.103
NOL11nucleolar protein 110.097
RPL36ALribosomal protein L36a-like0.097
RPL14ribosomal protein L140.094
RPS6ribosomal protein S60.087
RRP15ribosomal RNA processing 15 homolog (S. cerevisiae)0.086
MKI67IPMKI67 (FHA domain) interacting nucleolar phosphoprotein0.086
RPL11ribosomal protein L110.085
BMS1BMS1 homolog, ribosome assembly protein (yeast)0.085
DNAJC2DnaJ (Hsp40) homolog, subfamily C, member 20.083
WDR12WD repeat domain 120.077
RPL8ribosomal protein L80.075
CCDC59coiled-coil domain containing 590.071
FTSJ3FtsJ homolog 3 (E. coli)0.064
RPL19ribosomal protein L190.063
RRP9ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)0.060
ATAD3AATPase family, AAA domain containing 3A0.056
RPS7ribosomal protein S70.056
C14orf166chromosome 14 open reading frame 1660.052
WDR43WD repeat domain 430.049
RPL24ribosomal protein L240.049
RPL5ribosomal protein L50.048
RPL13ribosomal protein L130.045
RPS10ribosomal protein S100.045
RPL22ribosomal protein L220.043
RPL23Aribosomal protein L23a0.043
RPL10ribosomal protein L100.042
RPL15ribosomal protein L150.042
C8orf33chromosome 8 open reading frame 330.042
PTRH2peptidyl-tRNA hydrolase 20.041
NACAnascent polypeptide-associated complex alpha subunit0.040
LAS1LLAS1-like (S. cerevisiae)0.040
MDM4Mdm4 p53 binding protein homolog (mouse)0.040
EEF2eukaryotic translation elongation factor 20.036
BCAS2breast carcinoma amplified sequence 20.036
DHX37DEAH (Asp-Glu-Ala-His) box polypeptide 370.036
NAT10N-acetyltransferase 10 (GCN5-related)0.035
RPP40ribonuclease P/MRP 40kDa subunit0.034
NCLnucleolin0.034
POLR1Cpolymerase (RNA) I polypeptide C, 30kDa0.034
NOP58NOP58 ribonucleoprotein homolog (yeast)0.033
RPLP0ribosomal protein, large, P00.032
WDR74WD repeat domain 740.032
NOL7nucleolar protein 7, 27kDa0.031
PAK1IP1PAK1 interacting protein 10.031
WDR5WD repeat domain 50.030
EEF1E1eukaryotic translation elongation factor 1 epsilon 10.029
POLR1Epolymerase (RNA) I polypeptide E, 53kDa0.028
NOL8nucleolar protein 80.028
RPL10Aribosomal protein L10a0.027
TRMT1TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)0.027
WDR3WD repeat domain 30.026
TEX10testis expressed 100.026
CIRH1Acirrhosis, autosomal recessive 1A (cirhin)0.026
NOC2Lnucleolar complex associated 2 homolog (S. cerevisiae)0.026
SUGP1SURP and G patch domain containing 10.026
RPL37Aribosomal protein L37a0.025
NDUFB3NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa0.025
WDR75WD repeat domain 750.024
WDR46WD repeat domain 460.023
PINX1PIN2/TERF1 interacting, telomerase inhibitor 10.023
RPL21ribosomal protein L210.023
EIF3Eeukaryotic translation initiation factor 3, subunit E0.023
RPL9ribosomal protein L90.022
TSR1TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)0.022
OSGEPO-sialoglycoprotein endopeptidase0.021
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG8939CG8939 gene product from transcript CG8939-RA0.964
CG1785CG1785 gene product from transcript CG1785-RA0.899
eIF-3p40Eukaryotic initiation factor 3 p40 subunit0.882
CG30349CG30349 gene product from transcript CG30349-RA0.819
Int6Int6 homologue0.777
Nap1Nucleosome assembly protein 10.765
RpL35ARibosomal protein L35A0.744
CG4364CG4364 gene product from transcript CG4364-RA0.673
Ip259Intronic Protein 2590.613
RpL17Ribosomal protein L170.609
reptreptin0.608
bysby S60.599
RpL3Ribosomal protein L30.577
Rs1CG2173 gene product from transcript CG2173-RA0.555
RpS4Ribosomal protein S40.549
RpI135RNA polymerase I 135kD subunit0.525
Ef2bElongation factor 2b0.525
RpL23ARibosomal protein L23A0.504
CG9253CG9253 gene product from transcript CG9253-RA0.471
CG9246CG9246 gene product from transcript CG9246-RA0.458
CG8801CG8801 gene product from transcript CG8801-RA0.444
CG1542CG1542 gene product from transcript CG1542-RA0.432
CG7686CG7686 gene product from transcript CG7686-RA0.430
RpL26Ribosomal protein L260.430
RpL7Ribosomal protein L70.419
Sas10CG4202 gene product from transcript CG4202-RA0.406
pitpitchoune0.406
CG10286CG10286 gene product from transcript CG10286-RA0.399
RpS8Ribosomal protein S80.387
l(1)G0020lethal (1) G00200.375
Art3Arginine methyltransferase 30.370
RpS26Ribosomal protein S260.349
sopstring of pearls0.342
CG6724CG6724 gene product from transcript CG6724-RA0.329
CG2691CG2691 gene product from transcript CG2691-RA0.329
l(2)k09022lethal (2) k090220.327
RpL37aRibosomal protein L37a0.321
RpL11Ribosomal protein L110.308
CG11583CG11583 gene product from transcript CG11583-RA0.307
nop5CG10206 gene product from transcript CG10206-RA0.287
CG3335CG3335 gene product from transcript CG3335-RA0.287
CG1234CG1234 gene product from transcript CG1234-RA0.283
CG12301CG12301 gene product from transcript CG12301-RA0.282
CG7993CG7993 gene product from transcript CG7993-RA0.281
RpS5aRibosomal protein S5a0.278
CG12325CG12325 gene product from transcript CG12325-RA0.277
l(3)07882lethal (3) 078820.268
RpL13ARibosomal protein L13A0.267
l(2)09851lethal (2) 098510.263
CG1671CG1671 gene product from transcript CG1671-RA0.249
stastubarista0.249
CG18178CG18178 gene product from transcript CG18178-RA0.248
Mat89BaMaternal transcript 89Ba0.242
Csl4CG6249 gene product from transcript CG6249-RA0.240
Nop56CG13849 gene product from transcript CG13849-RA0.239
CG3756CG3756 gene product from transcript CG3756-RA0.235
Nmd3Nonsense-mediated mRNA 30.231
Tango7Transport and Golgi organization 70.227
CG9630CG9630 gene product from transcript CG9630-RA0.227
RpL18Ribosomal protein L180.226
RpL27Ribosomal protein L270.223
CG9769CG9769 gene product from transcript CG9769-RA0.212
RpS6Ribosomal protein S60.211
Dis3CG6413 gene product from transcript CG6413-RA0.199
RpL18ARibosomal protein L18A0.196
Mys45AMystery 45A0.194
RpL10AbRibosomal protein L10Ab0.190
CG7845CG7845 gene product from transcript CG7845-RB0.189
CG8064CG8064 gene product from transcript CG8064-RA0.189
CG6937CG6937 gene product from transcript CG6937-RA0.180
CG2875CG2875 gene product from transcript CG2875-RB0.178
CG9107CG9107 gene product from transcript CG9107-RA0.176
RpS15Ribosomal protein S150.175
Rack1Receptor of activated protein kinase C 10.173
RpL7ARibosomal protein L7A0.165
CG5018CG5018 gene product from transcript CG5018-RA0.158
CG11180CG11180 gene product from transcript CG11180-RA0.150
RpL4Ribosomal protein L40.148
sspsunspot0.144
RpS7Ribosomal protein S70.141
AGO1Argonaute-10.141
CG5033CG5033 gene product from transcript CG5033-RA0.141
RpS16Ribosomal protein S160.140
RpL22Ribosomal protein L220.137
CG6712CG6712 gene product from transcript CG6712-RA0.130
CG9890CG9890 gene product from transcript CG9890-RA0.127
ns1nucleostemin 10.126
CG10565CG10565 gene product from transcript CG10565-RA0.126
RpLP0Ribosomal protein LP00.125
RpL13Ribosomal protein L130.118
Trip1CG8882 gene product from transcript CG8882-RA0.117
CG4554CG4554 gene product from transcript CG4554-RA0.113
RpL24-likeRibosomal protein L24-like0.111
Ef1betaElongation factor 1 beta0.111
NHP2CG5258 gene product from transcript CG5258-RA0.107
CG2260CG2260 gene product from transcript CG2260-RA0.104
CG5642CG5642 gene product from transcript CG5642-RA0.104
CG4038CG4038 gene product from transcript CG4038-RA0.102
CG9799CG9799 gene product from transcript CG9799-RA0.099
RpS13Ribosomal protein S130.095
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Mybbp1aMYB binding protein (P160) 1a0.506
Nop56NOP56 ribonucleoprotein homolog (yeast)0.236
Eedembryonic ectoderm development0.231
Gnl3guanine nucleotide binding protein-like 3 (nucleolar)0.137
Wdr74WD repeat domain 740.123
Wdr43WD repeat domain 430.117
Gm10335predicted gene 103350.075
Lsg1large subunit GTPase 1 homolog (S. cerevisiae)0.072
Rpl32ribosomal protein L320.062
Rpl4ribosomal protein L40.059
Per1period homolog 1 (Drosophila)0.042
Mak16MAK16 homolog (S. cerevisiae)0.039
Rpl23ribosomal protein L230.037
Ltv1LTV1 homolog (S. cerevisiae)0.035
Nacanascent polypeptide-associated complex alpha polypeptide0.032
Mki67ipMki67 (FHA domain) interacting nucleolar phosphoprotein0.032
Ftsj3FtsJ homolog 3 (E. coli)0.031
Rarsarginyl-tRNA synthetase0.026
D19Bwg1357eDNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed0.026
Rpl3ribosomal protein L30.026
Nolc1nucleolar and coiled-body phosphoprotein 10.024
Rpl7ribosomal protein L70.023
Rrp12ribosomal RNA processing 12 homolog (S. cerevisiae)0.023
Utp20UTP20, small subunit (SSU) processome component, homolog (yeast)0.023
Ddx21DEAD (Asp-Glu-Ala-Asp) box polypeptide 210.022
Ppanpeter pan homolog (Drosophila)0.022
Gm10119predicted gene 101190.022
LOC10004462760S ribosomal protein L23-like0.020
Grwd1glutamate-rich WD repeat containing 10.020
Nop2NOP2 nucleolar protein homolog (yeast)0.020
Nop58NOP58 ribonucleoprotein homolog (yeast)0.020
Cct2chaperonin containing Tcp1, subunit 2 (beta)0.019
Rrp1bribosomal RNA processing 1 homolog B (S. cerevisiae)0.019
Ccdc86coiled-coil domain containing 860.018
Gnl2guanine nucleotide binding protein-like 2 (nucleolar)0.018
Rpl36aribosomal protein L36A0.018
Rsl1d1ribosomal L1 domain containing 10.016
Npm1nucleophosmin 10.016
Rpl35ribosomal protein L350.015
Rps24ribosomal protein S240.015
Ddx10DEAD (Asp-Glu-Ala-Asp) box polypeptide 100.015
Farsbphenylalanyl-tRNA synthetase, beta subunit0.015
Rpl26ribosomal protein L260.015
Tsr1TSR1, 20S rRNA accumulation, homolog (yeast)0.015
Pwp1PWP1 homolog (S. cerevisiae)0.015
Rrp15ribosomal RNA processing 15 homolog (S. cerevisiae)0.013
Pwp2PWP2 periodic tryptophan protein homolog (yeast)0.013
Nol11nucleolar protein 110.013
Eif2s1eukaryotic translation initiation factor 2, subunit 1 alpha0.013
Rnaseh1ribonuclease H10.013
Dimt1DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)0.013
Polr1epolymerase (RNA) I polypeptide E0.013
Tarsthreonyl-tRNA synthetase0.013
Wdr46WD repeat domain 460.012
Rpl5ribosomal protein L50.012
Per2period homolog 2 (Drosophila)0.011
Eif3deukaryotic translation initiation factor 3, subunit D0.011
Nop14NOP14 nucleolar protein homolog (yeast)0.011
Aatfapoptosis antagonizing transcription factor0.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
TIF6Tif6p1.000
SSF1Ssf1p0.999
CIC1Cic1p0.998
MAK21Mak21p0.997
DBP10Dbp10p0.996
NOG1Nog1p0.996
RLP7Rlp7p0.996
NOP7Nop7p0.993
NIP7Nip7p0.988
DRS1Drs1p0.987
NOP4Nop4p0.985
PUF6Puf6p0.983
NOC2Noc2p0.983
RIX1Rix1p0.981
NOP12Nop12p0.977
RPF2Rpf2p0.972
ARX1Arx1p0.971
BRX1Brx1p0.953
NSA1Nsa1p0.950
NOP2Nop2p0.945
NOC3Noc3p0.925
RPF1Rpf1p0.923
RPL8BRpl8bp0.922
HAS1Has1p0.920
RPL5Rpl5p0.882
YTM1Ytm1p0.876
RRP5Rrp5p0.874
MRT4Mrt4p0.874
BUD20Bud20p0.872
RRP15Rrp15p0.862
NOP15Nop15p0.841
NSA2Nsa2p0.836
RPL3Rpl3p0.834
MDN1Mdn1p0.820
SPB4Spb4p0.810
SPB1Spb1p0.808
ERB1Erb1p0.802
RPL36BRpl36bp0.787
RLP24Rlp24p0.751
MAK11Mak11p0.744
IPI3Ipi3p0.741
DBP3Dbp3p0.737
RIX7Rix7p0.732
EBP2Ebp2p0.730
SDA1Sda1p0.724
NUG1Nug1p0.710
NOG2Nog2p0.697
NOP13Nop13p0.692
RPL20ARpl20ap0.655
RPL8ARpl8ap0.655
RSA4Rsa4p0.618
RPL25Rpl25p0.610
DBP9Dbp9p0.565
RPL1BRpl1bp0.530
CBF5Cbf5p0.527
LTV1Ltv1p0.508
RPL28Rpl28p0.463
YNL260Chypothetical protein0.457
MAK5Mak5p0.432
URB2Urb2p0.430
NOP16Nop16p0.427
RPL7ARpl7ap0.425
PWP1Pwp1p0.411
RRP17Rrp17p0.408
NMD3Nmd3p0.379
LAS1Las1p0.359
RPL13ARpl13ap0.352
RNT1Rnt1p0.350
RRS1Rrs1p0.349
RPL19ARpl19ap0.348
RPL16ARpl16ap0.348
RRP1Rrp1p0.347
NOP8Nop8p0.337
RRP14Rrp14p0.320
URB1Urb1p0.306
RPL30Rpl30p0.282
RSA1Rsa1p0.279
ALB1Alb1p0.275
GAR1Gar1p0.270
RPL31ARpl31ap0.266
FYV7Fyv7p0.241
FPR4Fpr4p0.235
GUS1Gus1p0.222
PRS3Prs3p0.219
RPL10Rpl10p0.216
RPL17ARpl17ap0.215
YEF3Yef3p0.206
ARB1Arb1p0.206
FUN12Fun12p0.203
GDS1Gds1p0.195
RPS14BRps14bp0.192
RPL1ARpl1ap0.191
LOC1Loc1p0.189
RMT2Rmt2p0.178
DBP2Dbp2p0.177
ATC1Atc1p0.175
RRP36Rrp36p0.173
SLX9Slx9p0.168
TEF1Tef1p0.166
BUD22Bud22p0.166