The network for 'regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter

Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.

NameDescriptionProbabilityFunc Analog Organism
PPARAperoxisome proliferator-activated receptor alpha0.999
CREBBPCREB binding protein0.996
NCOR1nuclear receptor corepressor 10.994
NCOA1nuclear receptor coactivator 10.993
RARAretinoic acid receptor, alpha0.993
RXRAretinoid X receptor, alpha0.992
ESR1estrogen receptor 10.954
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.928
NCOR2nuclear receptor corepressor 20.914
EP300E1A binding protein p3000.868
ARandrogen receptor0.855
MED25mediator complex subunit 250.572
SIN3ASIN3 homolog A, transcription regulator (yeast)0.520
NCOA6nuclear receptor coactivator 60.431
NCOA3nuclear receptor coactivator 30.426
SIRT1sirtuin 10.314
NCOA2nuclear receptor coactivator 20.285
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.279
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.273
HDAC3histone deacetylase 30.253
HNF4Ahepatocyte nuclear factor 4, alpha0.227
SP1Sp1 transcription factor0.187
PGRprogesterone receptor0.161
TRRAPtransformation/transcription domain-associated protein0.148
RUNX1runt-related transcription factor 10.117
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.108
C16orf53chromosome 16 open reading frame 530.074
FHL2four and a half LIM domains 20.074
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.073
BCL6B-cell CLL/lymphoma 60.070
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.069
TADA2Atranscriptional adaptor 2A0.064
NR2E3nuclear receptor subfamily 2, group E, member 30.064
HDAC4histone deacetylase 40.063
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.055
FOXO3forkhead box O30.054
SKIv-ski sarcoma viral oncogene homolog (avian)0.052
USP22ubiquitin specific peptidase 220.042
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.042
SKILSKI-like oncogene0.040
HRhairless homolog (mouse)0.039
MED1mediator complex subunit 10.038
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.037
PMLpromyelocytic leukemia0.033
ACACAacetyl-CoA carboxylase alpha0.028
NR0B2nuclear receptor subfamily 0, group B, member 20.028
HDAC7histone deacetylase 70.028
HDAC5histone deacetylase 50.027
TNIKTRAF2 and NCK interacting kinase0.027
ESRRGestrogen-related receptor gamma0.025
ATXN1Lataxin 1-like0.024
PRKD2protein kinase D20.024
PPARGperoxisome proliferator-activated receptor gamma0.023
SMAD3SMAD family member 30.023
ITGB1BP2integrin beta 1 binding protein (melusin) 20.023
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.022
HTThuntingtin0.021
HIPK2homeodomain interacting protein kinase 20.020
ESR2estrogen receptor 2 (ER beta)0.020
TP53tumor protein p530.020
THRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)0.019
GRIP1glutamate receptor interacting protein 10.019
RXRBretinoid X receptor, beta0.018
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.018
THRBthyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)0.017
MYST1MYST histone acetyltransferase 10.017
PSEN1presenilin 10.017
SMAD4SMAD family member 40.016
RXRGretinoid X receptor, gamma0.015
HDAC10histone deacetylase 100.015
ZMYND11zinc finger, MYND-type containing 110.015
PRMT2protein arginine methyltransferase 20.015
TADA3transcriptional adaptor 30.014
SMAD2SMAD family member 20.013
JUPjunction plakoglobin0.013
DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.013
SRFserum response factor (c-fos serum response element-binding transcription factor)0.013
TBL1Xtransducin (beta)-like 1X-linked0.012
HBP1HMG-box transcription factor 10.012
CREB1cAMP responsive element binding protein 10.012
SUPT3Hsuppressor of Ty 3 homolog (S. cerevisiae)0.012
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.012
DAXXdeath-domain associated protein0.012
HIC1hypermethylated in cancer 10.012
TRMT1TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)0.012
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 30.011
MDM2Mdm2 p53 binding protein homolog (mouse)0.011
EMDemerin0.011
KLHL24kelch-like 24 (Drosophila)0.011
SRCAPSnf2-related CREBBP activator protein0.010
ZBTB16zinc finger and BTB domain containing 160.010
PELP1proline, glutamate and leucine rich protein 10.010
TCF4transcription factor 40.010
BCS1LBCS1-like (S. cerevisiae)0.010
NR1H3nuclear receptor subfamily 1, group H, member 30.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cdkn1bcyclin-dependent kinase inhibitor 1B0.970
Lef1lymphoid enhancer binding factor 10.963
Csrp2bpcysteine and glycine-rich protein 2 binding protein0.946
Notch1Notch gene homolog 1 (Drosophila)0.934
Tada2atranscriptional adaptor 2A0.855
Trp53transformation related protein 530.834
Tcf7transcription factor 7, T-cell specific0.798
Rbbp5retinoblastoma binding protein 50.556
Ctnnb1catenin (cadherin associated protein), beta 10.556
Ptenphosphatase and tensin homolog0.545
Wdr5WD repeat domain 50.534
Kat2aK(lysine) acetyltransferase 2A0.520
Tada3transcriptional adaptor 30.305
CrebbpCREB binding protein0.288
Axin2axin20.280
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.245
Srebf2sterol regulatory element binding factor 20.231
Ash2lash2 (absent, small, or homeotic)-like (Drosophila)0.218
Men1multiple endocrine neoplasia 10.217
Arandrogen receptor0.202
Esr1estrogen receptor 1 (alpha)0.124
Gata6GATA binding protein 60.123
Gata4GATA binding protein 40.120
Fgfr1fibroblast growth factor receptor 10.116
Efnb2ephrin B20.107
Hdac7histone deacetylase 70.105
Npc1Niemann Pick type C10.098
Kitkit oncogene0.090
Trraptransformation/transcription domain-associated protein0.090
Yeats2YEATS domain containing 20.078
Hes1hairy and enhancer of split 1 (Drosophila)0.077
Rb1retinoblastoma 10.076
Mapk14mitogen-activated protein kinase 140.064
Ep300E1A binding protein p3000.061
L3mbtl2l(3)mbt-like 2 (Drosophila)0.060
Pou5f1POU domain, class 5, transcription factor 10.058
Prlrprolactin receptor0.055
Six5sine oculis-related homeobox 5 homolog (Drosophila)0.053
Taf5lTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor0.052
Kiss1KiSS-1 metastasis-suppressor0.052
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.050
Taf6lTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor0.050
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.047
Ncdnneurochondrin0.046
Tgif2TGFB-induced factor homeobox 20.046
Atxn7ataxin 70.044
Tbx3T-box 30.043
Irs2insulin receptor substrate 20.040
Psen1presenilin 10.039
Arhgef1Rho guanine nucleotide exchange factor (GEF) 10.036
E2f1E2F transcription factor 10.035
Polr2apolymerase (RNA) II (DNA directed) polypeptide A0.035
Hcfc1host cell factor C10.035
Leprleptin receptor0.034
Sun2Sad1 and UNC84 domain containing 20.032
Mbd3methyl-CpG binding domain protein 30.032
Bcl2B-cell leukemia/lymphoma 20.029
Axin1axin 10.028
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.027
MecomMDS1 and EVI1 complex locus0.026
Lhcgrluteinizing hormone/choriogonadotropin receptor0.026
Nolc1nucleolar and coiled-body phosphoprotein 10.026
Ppargperoxisome proliferator activated receptor gamma0.025
Dll1delta-like 1 (Drosophila)0.025
Mapkapk2MAP kinase-activated protein kinase 20.024
Foxo3forkhead box O30.024
BrafBraf transforming gene0.024
Cherpcalcium homeostasis endoplasmic reticulum protein0.023
Tcof1Treacher Collins Franceschetti syndrome 1, homolog0.023
Hif1ahypoxia inducible factor 1, alpha subunit0.023
Tefthyrotroph embryonic factor0.023
Pygo2pygopus 20.022
Nficnuclear factor I/C0.022
Foxa2forkhead box A20.022
Sox2SRY-box containing gene 20.022
Tcfcp2l1transcription factor CP2-like 10.022
Pax2paired box gene 20.021
Rbl2retinoblastoma-like 20.021
Tenc1tensin like C1 domain-containing phosphatase0.021
Nf2neurofibromatosis 20.020
Zfp362zinc finger protein 3620.019
Creb1cAMP responsive element binding protein 10.019
Klf13Kruppel-like factor 130.019
Ggnbp1gametogenetin binding protein 10.019
Tnks1bp1tankyrase 1 binding protein 10.019
Git1G protein-coupled receptor kinase-interactor 10.019
Sall4sal-like 4 (Drosophila)0.019
Sf3a2splicing factor 3a, subunit 20.018
Chst8carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 80.018
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.018
Wdfy2WD repeat and FYVE domain containing 20.018
Crb2crumbs homolog 2 (Drosophila)0.018
Skiski sarcoma viral oncogene homolog (avian)0.018
Ccnd1cyclin D10.018
Atxn7l3ataxin 7-like 30.017
Mybbp1aMYB binding protein (P160) 1a0.017
Hsf1heat shock factor 10.017
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.017
Fzd8frizzled homolog 8 (Drosophila)0.017
Emx1empty spiracles homolog 1 (Drosophila)0.017
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CAT8Cat8p0.102
SNT1Snt1p0.088
MIG2Mig2p0.063
SNF1Snf1p0.056
MIG1Mig1p0.056
SIN3Sin3p0.050
HAL5Hal5p0.049
HST1Hst1p0.049
HOS2Hos2p0.037
SWI1Swi1p0.037
RDS2Rds2p0.033
CTI6Cti6p0.030
NDD1Ndd1p0.027
ROX1Rox1p0.027
MSN2Msn2p0.027
MIG3Mig3p0.026
YKR075Chypothetical protein0.025
PIB1Pib1p0.025
YKL187Chypothetical protein0.023
MET4Met4p0.023
YOR385Whypothetical protein0.023
MYO5Myo5p0.020
SFL1Sfl1p0.019
TBS1Tbs1p0.019
SPF1Spf1p0.018
PSK2Psk2p0.018
ERT1Ert1p0.018
NRG1Nrg1p0.018
RIM4Rim4p0.018
IZH4Izh4p0.017
DIA1Dia1p0.017
YNL234Whypothetical protein0.017
GLN3Gln3p0.017
CYC8Cyc8p0.017
VHR1Vhr1p0.016
MGA2Mga2p0.016
HXT3Hxt3p0.016
NUP157Nup157p0.016
MBR1Mbr1p0.016
SSK2Ssk2p0.016
ZAP1Zap1p0.016
MTL1Mtl1p0.015
FPK1Fpk1p0.015
SGF73Sgf73p0.015
YPK2Ypk2p0.015
DAL81Dal81p0.015
HSF1Hsf1p0.015
HAL1Hal1p0.014
FMP48Fmp48p0.014
SEC28Sec28p0.014
IRC23Irc23p0.013
CSR2Csr2p0.013
MKK2Mkk2p0.013
CPR1Cpr1p0.013
POG1Pog1p0.013
YAP5Yap5p0.013
RGS2Rgs2p0.013
RTG3Rtg3p0.013
PCL2Pcl2p0.013
MOT3Mot3p0.013
SMP1Smp1p0.012
HAA1Haa1p0.012
FAA2Faa2p0.012
ECM22Ecm22p0.012
SCH9Sch9p0.012
SPT8Spt8p0.012
RPI1Rpi1p0.012
HST3Hst3p0.012
AFT1Aft1p0.012
SKS1Sks1p0.012
HDA2Hda2p0.012
GIP2Gip2p0.011
YNL194Chypothetical protein0.011
VID24Vid24p0.011
SRD1Srd1p0.011
SOR2Sor2p0.011
SCT1Sct1p0.011
RPN4Rpn4p0.011
ARG80Arg80p0.011
SET1Set1p0.011
PEP5Pep5p0.011
RLM1Rlm1p0.011
STL1Stl1p0.010
ALY1Aly1p0.010
YKR096Whypothetical protein0.010
SKY1Sky1p0.010
CHS2Chs2p0.010
WSC4Wsc4p0.010
GAL11Gal11p0.010