The network for 'canonical wnt signaling pathway involved in mesenchymal stem cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

canonical wnt signaling pathway involved in mesenchymal stem cell differentiation

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation.

NameDescriptionProbabilityFunc Analog Organism
BBS10Bardet-Biedl syndrome 101.000
WNT3Awingless-type MMTV integration site family, member 3A0.998
FGF18fibroblast growth factor 180.990
SFRP1secreted frizzled-related protein 10.987
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.971
WNT5Awingless-type MMTV integration site family, member 5A0.965
ELF5E74-like factor 5 (ets domain transcription factor)0.962
NDPNorrie disease (pseudoglioma)0.917
FOXF2forkhead box F20.856
IHHIndian hedgehog0.839
WIF1WNT inhibitory factor 10.705
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.685
AQP5aquaporin 50.641
CXCL14chemokine (C-X-C motif) ligand 140.579
MMP11matrix metallopeptidase 11 (stromelysin 3)0.543
PLXDC1plexin domain containing 10.542
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.521
WNT10Awingless-type MMTV integration site family, member 10A0.488
BMP4bone morphogenetic protein 40.456
EHFets homologous factor0.443
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.435
FZD8frizzled homolog 8 (Drosophila)0.402
ENTPD2ectonucleoside triphosphate diphosphohydrolase 20.378
MXRA5matrix-remodelling associated 50.358
SOX21SRY (sex determining region Y)-box 210.357
C7orf36chromosome 7 open reading frame 360.356
HES2hairy and enhancer of split 2 (Drosophila)0.352
LBX1ladybird homeobox 10.311
WNT1wingless-type MMTV integration site family, member 10.311
UBQLN4ubiquilin 40.298
FOXE1forkhead box E1 (thyroid transcription factor 2)0.294
FGF8fibroblast growth factor 8 (androgen-induced)0.268
FZD1frizzled homolog 1 (Drosophila)0.261
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.251
RGS2regulator of G-protein signaling 2, 24kDa0.248
FGF4fibroblast growth factor 40.236
FZD7frizzled homolog 7 (Drosophila)0.221
LRP6low density lipoprotein receptor-related protein 60.212
INHBBinhibin, beta B0.211
PAX7paired box 70.206
FGF3fibroblast growth factor 30.200
TNFSF11tumor necrosis factor (ligand) superfamily, member 110.198
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.186
FOXF1forkhead box F10.186
PAX3paired box 30.183
HOXD13homeobox D130.176
FBLN1fibulin 10.169
ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif, 20.163
BMP7bone morphogenetic protein 70.157
PTGISprostaglandin I2 (prostacyclin) synthase0.154
FOXL1forkhead box L10.153
TLX3T-cell leukemia homeobox 30.151
POU3F1POU class 3 homeobox 10.149
HOXD11homeobox D110.146
SFRP2secreted frizzled-related protein 20.130
HOXB1homeobox B10.128
FOXB1forkhead box B10.124
WNT6wingless-type MMTV integration site family, member 60.120
HMX1H6 family homeobox 10.120
LMX1ALIM homeobox transcription factor 1, alpha0.120
PRRX2paired related homeobox 20.118
NPAS1neuronal PAS domain protein 10.117
P2RX2purinergic receptor P2X, ligand-gated ion channel, 20.112
HOXC8homeobox C80.109
HS3ST6heparan sulfate (glucosamine) 3-O-sulfotransferase 60.108
GPR124G protein-coupled receptor 1240.108
NKX3-2NK3 homeobox 20.108
SIX2SIX homeobox 20.106
EPHB3EPH receptor B30.103
DLX4distal-less homeobox 40.102
RAXretina and anterior neural fold homeobox0.100
PKP1plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)0.100
NKD1naked cuticle homolog 1 (Drosophila)0.099
GUCA2Aguanylate cyclase activator 2A (guanylin)0.096
WNT3wingless-type MMTV integration site family, member 30.095
GAS1growth arrest-specific 10.095
SHHsonic hedgehog0.093
BMP8Abone morphogenetic protein 8a0.092
NOTCH3notch 30.092
LRRC17leucine rich repeat containing 170.091
WNT2wingless-type MMTV integration site family member 20.090
SOX1SRY (sex determining region Y)-box 10.089
CRLF1cytokine receptor-like factor 10.084
WNT4wingless-type MMTV integration site family, member 40.083
THBS2thrombospondin 20.083
OCA2oculocutaneous albinism II0.082
TWIST1twist homolog 1 (Drosophila)0.082
COL4A6collagen, type IV, alpha 60.081
HOXD10homeobox D100.081
WNT5Bwingless-type MMTV integration site family, member 5B0.081
SMAD1SMAD family member 10.080
CILPcartilage intermediate layer protein, nucleotide pyrophosphohydrolase0.079
COL11A1collagen, type XI, alpha 10.076
ROR2receptor tyrosine kinase-like orphan receptor 20.075
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.074
CYP26A1cytochrome P450, family 26, subfamily A, polypeptide 10.073
COL2A1collagen, type II, alpha 10.071
DUOX1dual oxidase 10.071
NXPH4neurexophilin 40.070
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism