The network for 'regulation of systemic arterial blood pressure by hormone' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of systemic arterial blood pressure by hormone

The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.

NameDescriptionProbabilityFunc Analog Organism
NOSTRINnitric oxide synthase trafficker0.829
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.730
PAX8paired box 80.391
VAC14Vac14 homolog (S. cerevisiae)0.382
HSPB1heat shock 27kDa protein 10.175
PSAPprosaposin0.173
CTSAcathepsin A0.171
ATP6AP1ATPase, H+ transporting, lysosomal accessory protein 10.117
CAV2caveolin 20.071
TIMP3TIMP metallopeptidase inhibitor 30.061
LAMP1lysosomal-associated membrane protein 10.059
TUBB8tubulin, beta 80.044
GRNgranulin0.042
AGTangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.039
GNSglucosamine (N-acetyl)-6-sulfatase0.039
MTHFD1methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase0.036
PGDphosphogluconate dehydrogenase0.033
CTSBcathepsin B0.030
CD164CD164 molecule, sialomucin0.029
CST3cystatin C0.029
TKTtransketolase0.026
ITM2Bintegral membrane protein 2B0.026
WFDC2WAP four-disulfide core domain 20.025
BDKRB2bradykinin receptor B20.025
SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 30.024
MUC4mucin 4, cell surface associated0.023
PIGRpolymeric immunoglobulin receptor0.021
FUT6fucosyltransferase 6 (alpha (1,3) fucosyltransferase)0.020
GLP1Rglucagon-like peptide 1 receptor0.017
PLD3phospholipase D family, member 30.017
KCTD15potassium channel tetramerisation domain containing 150.017
CAV1caveolin 1, caveolae protein, 22kDa0.017
GRINAglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.016
ST14suppression of tumorigenicity 14 (colon carcinoma)0.016
APLP2amyloid beta (A4) precursor-like protein 20.016
NEU1sialidase 1 (lysosomal sialidase)0.016
GABRG2gamma-aminobutyric acid (GABA) A receptor, gamma 20.015
FOLH1folate hydrolase (prostate-specific membrane antigen) 10.014
ATP6V0CATPase, H+ transporting, lysosomal 16kDa, V0 subunit c0.014
PRKCEprotein kinase C, epsilon0.014
PRR15Lproline rich 15-like0.013
SLC5A1solute carrier family 5 (sodium/glucose cotransporter), member 10.013
GUCY2Cguanylate cyclase 2C (heat stable enterotoxin receptor)0.013
LAMP2lysosomal-associated membrane protein 20.013
CRYABcrystallin, alpha B0.012
NUCB1nucleobindin 10.012
TPP1tripeptidyl peptidase I0.012
XDHxanthine dehydrogenase0.012
CASP10caspase 10, apoptosis-related cysteine peptidase0.012
TM4SF5transmembrane 4 L six family member 50.012
LAPTM4Alysosomal protein transmembrane 4 alpha0.011
PORP450 (cytochrome) oxidoreductase0.011
CYP17A1cytochrome P450, family 17, subfamily A, polypeptide 10.011
ASAH1N-acylsphingosine amidohydrolase (acid ceramidase) 10.011
ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific )0.011
TAC1tachykinin, precursor 10.011
CDX1caudal type homeobox 10.011
GAAglucosidase, alpha; acid0.011
ACANaggrecan0.011
EDNRBendothelin receptor type B0.011
PLGplasminogen0.011
TMPRSS2transmembrane protease, serine 20.011
TIMP2TIMP metallopeptidase inhibitor 20.011
VTNvitronectin0.011
SLC44A4solute carrier family 44, member 40.010
FXYD3FXYD domain containing ion transport regulator 30.010
GJB1gap junction protein, beta 1, 32kDa0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ren1renin 1 structural0.991
Agtr1aangiotensin II receptor, type 1a0.970
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.944
Klk1b5kallikrein 1-related peptidase b50.929
Leprleptin receptor0.666
Slc12a1solute carrier family 12, member 10.662
Klk1b11kallikrein 1-related peptidase b110.660
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.576
Scn5asodium channel, voltage-gated, type V, alpha0.547
Klk1b26kallikrein 1-related petidase b260.464
Umoduromodulin0.462
Col4a3collagen, type IV, alpha 30.461
Klk1b21kallikrein 1-related peptidase b210.432
F2coagulation factor II0.416
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.360
Klk1b27kallikrein 1-related peptidase b270.358
Klk1b8kallikrein 1-related peptidase b80.350
Pcdh12protocadherin 120.273
Klk1kallikrein 10.268
Klk1b16kallikrein 1-related peptidase b160.237
Klk1b4kallikrein 1-related pepidase b40.233
CrpC-reactive protein, pentraxin-related0.207
Mup4major urinary protein 40.200
Ctrb1chymotrypsinogen B10.197
Vegfavascular endothelial growth factor A0.197
Nos3nitric oxide synthase 3, endothelial cell0.173
Egfbp2epidermal growth factor binding protein type B0.170
Klk1b9kallikrein 1-related peptidase b90.167
Akr1c6aldo-keto reductase family 1, member C60.163
G6pc2glucose-6-phosphatase, catalytic, 20.159
Cpa3carboxypeptidase A3, mast cell0.157
Mcpt4mast cell protease 40.145
Cyp3a11cytochrome P450, family 3, subfamily a, polypeptide 110.145
Bdkrb2bradykinin receptor, beta 20.140
Try5trypsin 50.140
Tff2trefoil factor 2 (spasmolytic protein 1)0.137
Pahphenylalanine hydroxylase0.132
Clpscolipase, pancreatic0.131
Prss58protease, serine 580.123
Cela2achymotrypsin-like elastase family, member 2A0.121
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.120
Klk1b1kallikrein 1-related peptidase b10.115
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.114
Klk1b3kallikrein 1-related peptidase b30.113
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.112
Krt17keratin 170.110
Prss3protease, serine, 30.110
Sprr1bsmall proline-rich protein 1B0.109
Pigrpolymeric immunoglobulin receptor0.107
Cma1chymase 1, mast cell0.107
Agtr2angiotensin II receptor, type 20.103
Pik3c2gphosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide0.101
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.099
Apcsserum amyloid P-component0.097
Afmafamin0.096
Nr0b2nuclear receptor subfamily 0, group B, member 20.095
Klk1b24kallikrein 1-related peptidase b240.094
Ngpneutrophilic granule protein0.088
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.087
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.085
Gm10334predicted gene 103340.083
Ly6flymphocyte antigen 6 complex, locus F0.080
Aqp8aquaporin 80.079
Lhcgrluteinizing hormone/choriogonadotropin receptor0.078
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.078
Foxa2forkhead box A20.075
F12coagulation factor XII (Hageman factor)0.075
Acsm2acyl-CoA synthetase medium-chain family member 20.074
RhagRhesus blood group-associated A glycoprotein0.074
Hsd3b3hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 30.074
Tjp1tight junction protein 10.074
Albalbumin0.071
Tm4sf1transmembrane 4 superfamily member 10.071
Serpina1aserine (or cysteine) peptidase inhibitor, clade A, member 1A0.070
Upp2uridine phosphorylase 20.070
Cyp2c54cytochrome P450, family 2, subfamily c, polypeptide 540.070
Wt1Wilms tumor 1 homolog0.069
Retnlbresistin like beta0.069
2210010C04RikRIKEN cDNA 2210010C04 gene0.069
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.068
Zg16zymogen granule protein 160.068
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.067
Adam3a disintegrin and metallopeptidase domain 3 (cyritestin)0.066
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.065
Hgdhomogentisate 1, 2-dioxygenase0.063
Cps1carbamoyl-phosphate synthetase 10.062
Krtap6-1keratin associated protein 6-10.060
F9coagulation factor IX0.059
Tgthyroglobulin0.059
Sprr2ismall proline-rich protein 2I0.059
Ptgs2prostaglandin-endoperoxide synthase 20.058
Apohapolipoprotein H0.057
Wnk4WNK lysine deficient protein kinase 40.056
Rnase1ribonuclease, RNase A family, 1 (pancreatic)0.056
Sprr2hsmall proline-rich protein 2H0.053
KelKell blood group0.052
Cckarcholecystokinin A receptor0.051
Fshbfollicle stimulating hormone beta0.051
Ctsbcathepsin B0.050
Ccl22chemokine (C-C motif) ligand 220.050
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ahsgalpha-2-HS-glycoprotein0.013
Olr287olfactory receptor 2870.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism