The network for 'cell proliferation in forebrain' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell proliferation in forebrain

The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.

NameDescriptionProbabilityFunc Analog Organism
JAG1jagged 10.963
PGRprogesterone receptor0.963
PAX3paired box 30.961
FGF1fibroblast growth factor 1 (acidic)0.945
FGF10fibroblast growth factor 100.941
NOTCH1notch 10.924
SOX10SRY (sex determining region Y)-box 100.923
PPARAperoxisome proliferator-activated receptor alpha0.863
AP2A1adaptor-related protein complex 2, alpha 1 subunit0.808
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.748
FGF2fibroblast growth factor 2 (basic)0.731
FGFR2fibroblast growth factor receptor 20.620
EPS15epidermal growth factor receptor pathway substrate 150.564
NCOR1nuclear receptor corepressor 10.506
QKIquaking homolog, KH domain RNA binding (mouse)0.480
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.443
BBS4Bardet-Biedl syndrome 40.413
BCL6B-cell CLL/lymphoma 60.393
KIAA0368KIAA03680.359
NEDD4neural precursor cell expressed, developmentally down-regulated 40.357
FGF7fibroblast growth factor 70.301
MAP1Amicrotubule-associated protein 1A0.291
SKIv-ski sarcoma viral oncogene homolog (avian)0.277
ATXN1ataxin 10.269
ATXN1Lataxin 1-like0.267
FRS2fibroblast growth factor receptor substrate 20.258
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.225
FGF8fibroblast growth factor 8 (androgen-induced)0.199
FGF18fibroblast growth factor 180.196
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.182
WNT1wingless-type MMTV integration site family, member 10.178
SOX21SRY (sex determining region Y)-box 210.170
PRKCZprotein kinase C, zeta0.169
LRCH1leucine-rich repeats and calponin homology (CH) domain containing 10.162
FGF3fibroblast growth factor 30.152
LRP6low density lipoprotein receptor-related protein 60.149
SOX1SRY (sex determining region Y)-box 10.142
RPP14ribonuclease P/MRP 14kDa subunit0.138
CKAP5cytoskeleton associated protein 50.129
HDAC3histone deacetylase 30.126
NCOA1nuclear receptor coactivator 10.121
MEOX2mesenchyme homeobox 20.114
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.112
SYNE1spectrin repeat containing, nuclear envelope 10.111
RARAretinoic acid receptor, alpha0.109
RAXretina and anterior neural fold homeobox0.107
TRAF5TNF receptor-associated factor 50.106
LBX1ladybird homeobox 10.105
TP73tumor protein p730.105
FGFR1fibroblast growth factor receptor 10.098
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.097
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.096
FGFR3fibroblast growth factor receptor 30.095
ACTN2actinin, alpha 20.094
STON2stonin 20.093
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.085
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.084
FZD8frizzled homolog 8 (Drosophila)0.084
SIN3ASIN3 homolog A, transcription regulator (yeast)0.083
SPTBN4spectrin, beta, non-erythrocytic 40.083
NOSTRINnitric oxide synthase trafficker0.082
TACC1transforming, acidic coiled-coil containing protein 10.079
WIF1WNT inhibitory factor 10.078
WNT10Awingless-type MMTV integration site family, member 10A0.077
SFRP1secreted frizzled-related protein 10.077
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.075
NOTCH2notch 20.075
WNT3wingless-type MMTV integration site family, member 30.073
TRAF3IP1TNF receptor-associated factor 3 interacting protein 10.071
FBLN1fibulin 10.071
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.070
FOXD3forkhead box D30.069
LHX2LIM homeobox 20.068
CHD9chromodomain helicase DNA binding protein 90.068
HMGA2high mobility group AT-hook 20.067
STK36serine/threonine kinase 360.066
HDAC10histone deacetylase 100.064
HES2hairy and enhancer of split 2 (Drosophila)0.064
DLL1delta-like 1 (Drosophila)0.063
JAG2jagged 20.060
BHLHE23basic helix-loop-helix family, member e230.059
HOXC8homeobox C80.058
FOXE1forkhead box E1 (thyroid transcription factor 2)0.056
CCDC141coiled-coil domain containing 1410.054
POU3F1POU class 3 homeobox 10.053
CDX2caudal type homeobox 20.052
SUFUsuppressor of fused homolog (Drosophila)0.051
CCDC115coiled-coil domain containing 1150.051
SOX2SRY (sex determining region Y)-box 20.050
FEZF2FEZ family zinc finger 20.049
COL2A1collagen, type II, alpha 10.049
OTPorthopedia homeobox0.049
FOXL1forkhead box L10.049
WNT4wingless-type MMTV integration site family, member 40.047
PAX2paired box 20.047
SIX3SIX homeobox 30.046
SMAD1SMAD family member 10.046
CCNFcyclin F0.046
NKX2-2NK2 homeobox 20.045
MEMO1mediator of cell motility 10.045
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.991
zic1zic family member 1 (odd-paired homolog, Drosophila)0.990
otx1borthodenticle homolog 1b0.977
foxg1aforkhead box G1a0.953
sox2SRY-box containing gene 20.953
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.944
pax6apaired box gene 6a0.942
dladeltaA0.935
otx2orthodenticle homolog 20.913
zic4zic family member 40.904
barhl2BarH-like 20.902
sox19aSRY-box containing gene 19a0.901
sox1aSRY-box containing gene 1a0.882
nr2e1nuclear receptor subfamily 2, group E, member 10.869
emx1empty spiracles homeobox 10.844
fezf2FEZ family zinc finger 20.833
foxn4forkhead box N40.751
fzd8afrizzled homolog 8a0.735
sox3SRY-box containing gene 30.732
ascl1aachaete-scute complex-like 1a (Drosophila)0.698
otpborthopedia homolog b0.697
pax6bpaired box gene 6b0.678
emx3empty spiracles homeobox 30.650
eng2aengrailed 2a0.640
fgfr1bfibroblast growth factor receptor 1b0.633
fgfr2fibroblast growth factor receptor 20.609
mab21l2mab-21-like 20.606
scube2signal peptide, CUB domain, EGF-like 20.586
foxp2forkhead box P20.578
fgf3fibroblast growth factor 30.554
lmo3LIM domain only 30.553
lhx2bLIM homeobox 2b0.538
arxaristaless related homeobox0.530
ephb3aeph receptor B3a0.509
nkx2.2aNK2 transcription factor related 2a0.507
axin2axin 2 (conductin, axil)0.490
dbx1adeveloping brain homeobox 1a0.489
eng2bengrailed 2b0.473
her6hairy-related 60.446
pou3f3bPOU class 3 homeobox 3b0.445
olig3oligodendrocyte transcription factor 30.443
six3asine oculis homeobox homolog 3a0.420
lhx5LIM homeobox 50.407
crabp2acellular retinoic acid binding protein 2, a0.396
ascl1bachaete-scute complex-like 1b (Drosophila)0.386
zic2bzic family member 2 (odd-paired homolog, Drosophila) b0.381
irx7iroquois homeobox protein 70.380
dlddeltaD0.379
sox11aSRY-box containing gene 11a0.317
zic5zic family member 5 (odd-paired homolog, Drosophila)0.316
irx5airoquois homeobox protein 5a0.303
olig2oligodendrocyte lineage transcription factor 20.301
lhx1aLIM homeobox 1a0.295
epha4beph receptor A4b0.285
rx3retinal homeobox gene 30.279
nkx2.1aNK2 homeobox 1a0.277
pou3f1POU class 3 homeobox 10.241
lmo4aLIM domain only 4a0.239
rfx2regulatory factor X, 2 (influences HLA class II expression)0.237
her4.2hairy-related 4.20.234
gli3GLI-Kruppel family member GLI30.231
wnt8bwingless-type MMTV integration site family, member 8b0.209
gli2aGLI-Kruppel family member GLI2a0.207
gli1GLI-Kruppel family member 10.206
wnt3wingless-type MMTV integration site family, member 30.203
zbtb16azinc finger and BTB domain containing 16a0.201
pou3f2POU class 3 homeobox 20.190
shhasonic hedgehog a0.186
wnt11wingless-type MMTV integration site family, member 110.185
neurod4neurogenic differentiation 40.179
foxb1.1forkhead box B1.10.178
hmx4H6 family homeobox 40.173
col15a1bcollagen, type XV, alpha 1b0.169
pax7apaired box gene 7a0.168
znf503zinc finger protein 5030.164
sox11bSRY-box containing gene 11b0.162
dlcdeltaC0.160
rereaarginine-glutamic acid dipeptide (RE) repeats a0.151
dlx2adistal-less homeobox gene 2a0.150
her15.1hairy and enhancer of split-related 15.10.143
bhlhe22basic helix-loop-helix family, member e220.141
sfrp5secreted frizzled-related protein 50.140
mpped2metallophosphoesterase domain containing 20.138
neurog1neurogenin 10.135
eya1eyes absent homolog 10.135
cdh2cadherin 2, neuronal0.134
gbx2gastrulation brain homeo box 20.132
lfnglunatic fringe homolog0.132
wnt7bawingless-type MMTV integration site family, member 7Ba0.131
irx1airoquois homeobox protein 1, a0.130
msxcmuscle segment homeobox C0.128
st8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.124
epha4aeph receptor A4a0.122
rx2retinal homeobox gene 20.119
zgc:66326zgc:663260.110
pax2apaired box gene 2a0.109
nkx2.1bNK2 homeobox 1b0.109
hey1hairy/enhancer-of-split related with YRPW motif 10.108
tfap2ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.103
gata3GATA-binding protein 30.102
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Otx2orthodenticle homolog 2 (Drosophila)1.000
Gli3GLI-Kruppel family member GLI31.000
Pax6paired box gene 61.000
Shhsonic hedgehog1.000
Pax3paired box gene 30.999
Emx1empty spiracles homolog 1 (Drosophila)0.999
Sox2SRY-box containing gene 20.998
Pitx2paired-like homeodomain transcription factor 20.998
Gli2GLI-Kruppel family member GLI20.997
Pax2paired box gene 20.997
Lhx1LIM homeobox protein 10.997
Msx2homeobox, msh-like 20.992
Msx1homeobox, msh-like 10.992
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.989
Fgf8fibroblast growth factor 80.985
Emx2empty spiracles homolog 2 (Drosophila)0.985
Foxc1forkhead box C10.984
Tcfap2atranscription factor AP-2, alpha0.977
Fgfr1fibroblast growth factor receptor 10.961
Gbx2gastrulation brain homeobox 20.954
Lmx1aLIM homeobox transcription factor 1 alpha0.954
Bmp4bone morphogenetic protein 40.952
Dlx5distal-less homeobox 50.944
Lmx1bLIM homeobox transcription factor 1 beta0.938
Foxg1forkhead box G10.931
En1engrailed 10.926
Insm1insulinoma-associated 10.923
Wnt3awingless-related MMTV integration site 3A0.914
Bmp7bone morphogenetic protein 70.913
Otx1orthodenticle homolog 1 (Drosophila)0.913
Dkk1dickkopf homolog 1 (Xenopus laevis)0.911
Eya1eyes absent 1 homolog (Drosophila)0.906
Prrx1paired related homeobox 10.897
Hes5hairy and enhancer of split 5 (Drosophila)0.896
Sox11SRY-box containing gene 110.885
Sox9SRY-box containing gene 90.883
Alx4aristaless-like homeobox 40.868
Lhx3LIM homeobox protein 30.860
Isl1ISL1 transcription factor, LIM/homeodomain0.859
Hand1heart and neural crest derivatives expressed transcript 10.846
Smosmoothened homolog (Drosophila)0.839
Nognoggin0.804
Fgf15fibroblast growth factor 150.804
Ascl1achaete-scute complex homolog 1 (Drosophila)0.769
Neurod1neurogenic differentiation 10.764
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.750
Sox3SRY-box containing gene 30.748
Ror2receptor tyrosine kinase-like orphan receptor 20.732
Gscgoosecoid homeobox0.723
Tbrachyury0.685
Hes1hairy and enhancer of split 1 (Drosophila)0.650
Nodalnodal0.648
Dlx1distal-less homeobox 10.634
Prrx2paired related homeobox 20.632
Hoxa1homeobox A10.621
Rarbretinoic acid receptor, beta0.613
Chd7chromodomain helicase DNA binding protein 70.610
Wnt1wingless-related MMTV integration site 10.598
Hoxa2homeobox A20.586
Ctnnb1catenin (cadherin associated protein), beta 10.568
Fgf10fibroblast growth factor 100.568
Tcfap2ctranscription factor AP-2, gamma0.565
Lhx9LIM homeobox protein 90.553
Lef1lymphoid enhancer binding factor 10.549
Alx3aristaless-like homeobox 30.539
Chrdchordin0.522
Hand2heart and neural crest derivatives expressed transcript 20.518
Sall3sal-like 3 (Drosophila)0.515
Nr2e1nuclear receptor subfamily 2, group E, member 10.502
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.483
Pax8paired box gene 80.474
Mitfmicrophthalmia-associated transcription factor0.462
Col2a1collagen, type II, alpha 10.459
Tbx1T-box 10.456
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.456
Lhx5LIM homeobox protein 50.455
Foxd2forkhead box D20.450
Zic1zinc finger protein of the cerebellum 10.443
Alx1ALX homeobox 10.429
Foxb1forkhead box B10.428
Foxc2forkhead box C20.425
Neurog2neurogenin 20.422
Pou3f3POU domain, class 3, transcription factor 30.404
Fgf3fibroblast growth factor 30.403
Hoxd13homeobox D130.398
Rargretinoic acid receptor, gamma0.393
Wt1Wilms tumor 1 homolog0.389
Tbx15T-box 150.379
Efna4ephrin A40.369
Pax7paired box gene 70.367
Zic3zinc finger protein of the cerebellum 30.363
Sox1SRY-box containing gene 10.361
Hmx3H6 homeobox 30.359
Foxn1forkhead box N10.338
Gdnfglial cell line derived neurotrophic factor0.334
Sema5bsema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B0.330
Atoh7atonal homolog 7 (Drosophila)0.315
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.312
Pou3f4POU domain, class 3, transcription factor 40.311
Hoxd3homeobox D30.302
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Kcnc3potassium voltage gated channel, Shaw-related subfamily, member 30.096
Myo1cmyosin IC0.067
Prim1DNA primase, p49 subunit0.053
Glg1golgi apparatus protein 10.046
Aqp4aquaporin 40.042
Hk1hexokinase 10.042
Sbpspermine binding protein0.039
RorbRAR-related orphan receptor B0.037
Pcdhgc3protocadherin gamma subfamily C, 30.029
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.028
Npy5rneuropeptide Y receptor Y50.028
Rfc4replication factor C (activator 1) 40.027
Unc5bunc-5 homolog B (C. elegans)0.027
Rftn2raftlin family member 20.027
Adarb2adenosine deaminase, RNA-specific, B20.025
Ptprz1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.024
Celsr2cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)0.022
P2rx3purinergic receptor P2X, ligand-gated ion channel, 30.022
Znf532zinc finger protein 5320.022
Pcnaproliferating cell nuclear antigen0.022
Gna12guanine nucleotide binding protein (G protein) alpha 120.021
Mcm2minichromosome maintenance complex component 20.018
Grk1G protein-coupled receptor kinase 10.018
Akt2v-akt murine thymoma viral oncogene homolog 20.017
P2rx6purinergic receptor P2X, ligand-gated ion channel, 60.017
Dlx5distal-less homeobox 50.017
Apoa5apolipoprotein A-V0.017
Dchs1dachsous 1 (Drosophila)0.016
Itpr2inositol 1,4,5-triphosphate receptor, type 20.016
Hrhairless0.016
Phkg1phosphorylase kinase, gamma 10.015
Sema6csema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C0.015
RGD1309821similar to KIAA1161 protein0.015
Crybg3beta-gamma crystallin domain containing 30.015
Aqp5aquaporin 50.014
Nrg1neuregulin 10.014
Malmal, T-cell differentiation protein0.013
Grip1glutamate receptor interacting protein 10.013
Pou3f2POU class 3 homeobox 20.013
Cacna1icalcium channel, voltage-dependent, T type, alpha 1I subunit0.013
Unc13cunc-13 homolog C (C. elegans)0.013
Mobpmyelin-associated oligodendrocyte basic protein0.013
Chgbchromogranin B0.013
Dscc1defective in sister chromatid cohesion 1 homolog (S. cerevisiae)0.013
Zic1Zic family member 1 (odd-paired homolog, Drosophila)0.012
Grin2dglutamate receptor, ionotropic, N-methyl D-aspartate 2D0.012
Kcnk3potassium channel, subfamily K, member 30.012
Il5rainterleukin 5 receptor, alpha0.012
Smad7SMAD family member 70.012
Sod3superoxide dismutase 3, extracellular0.012
AboABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)0.012
Npr2natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)0.011
Grm1glutamate receptor, metabotropic 10.011
Dusp4dual specificity phosphatase 40.010
Opalinoligodendrocytic myelin paranodal and inner loop protein0.010
Nup205nucleoporin 2050.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism