The network for 'cellular component disassembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular component disassembly

A cellular process that results in the breakdown of a cellular component.

NameDescriptionProbabilityFunc Analog Organism
TP53tumor protein p530.998
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.996
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.988
SQSTM1sequestosome 10.970
ARID1AAT rich interactive domain 1A (SWI-like)0.966
HSPA8heat shock 70kDa protein 80.942
RBM8ARNA binding motif protein 8A0.938
ACTG1actin, gamma 10.889
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.843
BCL2L1BCL2-like 10.831
ACTBactin, beta0.826
TGFB1transforming growth factor, beta 10.822
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.800
FKBP1AFK506 binding protein 1A, 12kDa0.654
FGF1fibroblast growth factor 1 (acidic)0.642
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.632
CASP9caspase 9, apoptosis-related cysteine peptidase0.632
SRSF3serine/arginine-rich splicing factor 30.609
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.582
TRA2Btransformer 2 beta homolog (Drosophila)0.570
CDK2cyclin-dependent kinase 20.555
FLOT2flotillin 20.550
HDAC2histone deacetylase 20.526
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.523
MAP3K7mitogen-activated protein kinase kinase kinase 70.509
ITGB4integrin, beta 40.504
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.500
BCL2L11BCL2-like 11 (apoptosis facilitator)0.499
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.495
VDAC1voltage-dependent anion channel 10.487
BCL2B-cell CLL/lymphoma 20.481
CSNK2Bcasein kinase 2, beta polypeptide0.474
PBRM1polybromo 10.469
FLOT1flotillin 10.452
KIF23kinesin family member 230.444
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.443
SYVN1synovial apoptosis inhibitor 1, synoviolin0.436
TRAF6TNF receptor-associated factor 60.435
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.433
SRSF10serine/arginine-rich splicing factor 100.422
HIST1H1Chistone cluster 1, H1c0.420
MDM2Mdm2 p53 binding protein homolog (mouse)0.416
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.416
CDK1cyclin-dependent kinase 10.406
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.403
EIF4A3eukaryotic translation initiation factor 4A30.403
CHAF1Achromatin assembly factor 1, subunit A (p150)0.375
NBR1neighbor of BRCA1 gene 10.374
IRAK2interleukin-1 receptor-associated kinase 20.370
USP15ubiquitin specific peptidase 150.360
HIST1H2BGhistone cluster 1, H2bg0.358
WHSC1Wolf-Hirschhorn syndrome candidate 10.354
MARK2MAP/microtubule affinity-regulating kinase 20.353
TRIM63tripartite motif containing 630.342
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.326
CENPEcentromere protein E, 312kDa0.325
SEPT2septin 20.324
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.318
KIF5Bkinesin family member 5B0.312
EXOSC3exosome component 30.296
ARID2AT rich interactive domain 2 (ARID, RFX-like)0.280
TPM2tropomyosin 2 (beta)0.276
RACGAP1Rac GTPase activating protein 10.265
CORO1Ccoronin, actin binding protein, 1C0.264
MAP3K1mitogen-activated protein kinase kinase kinase 10.262
UBCubiquitin C0.256
FUNDC2FUN14 domain containing 20.249
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.249
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.243
CD14CD14 molecule0.232
SRSF2serine/arginine-rich splicing factor 20.230
CKAP5cytoskeleton associated protein 50.230
POU5F1POU class 5 homeobox 10.218
ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)0.214
APCadenomatous polyposis coli0.214
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.208
DFFADNA fragmentation factor, 45kDa, alpha polypeptide0.207
HIST1H2AEhistone cluster 1, H2ae0.207
ARID1BAT rich interactive domain 1B (SWI1-like)0.206
HIST2H2BEhistone cluster 2, H2be0.203
MAPRE1microtubule-associated protein, RP/EB family, member 10.202
EXOC1exocyst complex component 10.201
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.195
CENPFcentromere protein F, 350/400kDa (mitosin)0.194
ETF1eukaryotic translation termination factor 10.191
SOS1son of sevenless homolog 1 (Drosophila)0.191
MAPK8mitogen-activated protein kinase 80.190
TOP2Btopoisomerase (DNA) II beta 180kDa0.188
LAMB1laminin, beta 10.187
HIST1H2BDhistone cluster 1, H2bd0.186
MCTS1malignant T cell amplified sequence 10.183
APPamyloid beta (A4) precursor protein0.179
EXOSC10exosome component 100.179
ZMYND11zinc finger, MYND-type containing 110.179
RNR2l-rRNA0.176
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.175
KIF20Akinesin family member 20A0.174
PHLPP1PH domain and leucine rich repeat protein phosphatase 10.166
TEX11testis expressed 110.166
KIF4Akinesin family member 4A0.162
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
wu:fv91b12wu:fv91b120.378
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.295
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.253
flot1bflotillin 1b0.205
hmga1ahigh mobility group AT-hook 1a0.199
zgc:77052zgc:770520.173
anp32aacidic (leucine-rich) nuclear phosphoprotein 32 family, member A0.169
prkciprotein kinase C, iota0.169
cct6achaperonin containing TCP1, subunit 6A (zeta 1)0.155
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.152
snrpasmall nuclear ribonucleoprotein polypeptide A0.152
dzip1DAZ interacting protein 10.148
eef2l2eukaryotic translation elongation factor 2, like 20.146
mfn2mitofusin 20.144
srsf2serine/arginine-rich splicing factor 20.135
zgc:109901zgc:1099010.134
atp6v0cbATPase, H+ transporting, lysosomal, V0 subunit c, b0.132
kif14kinesin family member 140.123
smyhc1slow myosin heavy chain 10.119
prc1bprotein regulator of cytokinesis 1b0.117
nusap1nucleolar and spindle associated protein 10.115
tmem93transmembrane protein 930.113
krt8keratin 80.110
tpm3tropomyosin 30.110
sass6spindle assembly 6 homolog (C. elegans)0.107
zgc:91930zgc:919300.106
crb2acrumbs homolog 2a0.105
dlstdihydrolipoamide S-succinyltransferase0.102
tra2atransformer-2 alpha0.101
pitx3paired-like homeodomain transcription factor 30.099
pcnaproliferating cell nuclear antigen0.098
si:dkey-261h17.1si:dkey-261h17.10.098
zgc:101737zgc:1017370.097
snai1asnail homolog 1a (Drosophila)0.096
srsf6aserine/arginine-rich splicing factor 6a0.092
marsmethionine-tRNA synthetase0.092
cand1cullin-associated and neddylation-dissociated 10.091
prp19PRP19/PSO4 homolog (S. cerevisiae)0.091
rrm1ribonucleotide reductase M1 polypeptide0.090
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.089
smndc1survival motor neuron domain containing 10.087
ift88intraflagellar transport 88 homolog0.087
cul1acullin 1a0.085
zbtb4zinc finger and BTB domain containing 40.085
si:ch211-254d18.3si:ch211-254d18.30.084
sucla2succinate-CoA ligase, ADP-forming, beta subunit0.084
mbpmyelin basic protein0.084
disc1disrupted in schizophrenia 10.084
zgc:55461zgc:554610.083
zgc:65979zgc:659790.083
me2malic enzyme 2, NAD(+)-dependent, mitochondrial0.082
rpn2ribophorin II0.082
anp32bacidic (leucine-rich) nuclear phosphoprotein 32 family, member B0.081
dpf2lD4, zinc and double PHD fingers family 2, like0.081
ddx39bDEAD (Asp-Glu-Ala-Asp) box polypeptide 39b0.081
ckmacreatine kinase, muscle a0.080
rpa1replication protein A10.078
btg2B-cell translocation gene 20.078
cnihcornichon homolog (Drosophila)0.078
lmnb1lamin B10.078
plxna4plexin A40.078
pkd2polycystic kidney disease 20.078
si:ch211-197n10.2si:ch211-197n10.20.076
cotl1coactosin-like 1 (Dictyostelium)0.076
eif3s10eukaryotic translation initiation factor 3, subunit 10 (theta)0.076
ube2i2ubiquitin-conjugating enzyme E2I20.075
cnn3acalponin 3, acidic a0.075
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.074
cdc16cell division cycle 16 homolog (S. cerevisiae)0.074
tbeta-abeta thymosin-like protein 20.073
mta2metastasis associated 1 family, member 20.073
ranras-related nuclear protein0.073
smad9MAD homolog 9 (Drosophila)0.073
asna1arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)0.073
si:dkey-181m9.9si:dkey-181m9.90.072
cse1lchromosome segregation 1-like (S. cerevisiae)0.072
sirt6sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)0.072
wnt11wingless-type MMTV integration site family, member 110.072
zgc:110527zgc:1105270.071
mapk3mitogen-activated protein kinase 30.071
usp5ubiquitin specific protease 50.071
eif5aeukaryotic translation initiation factor 5A0.071
hk1hexokinase 10.071
zgc:112242zgc:1122420.071
syncriplsynaptotagmin binding, cytoplasmic RNA interacting protein, like0.071
lypd6LY6/PLAUR domain containing 60.070
arpp19bcAMP-regulated phosphoprotein 19b0.070
kdm5clysine (K)-specific demethylase 5C0.070
mdm2transformed 3T3 cell double minute 2 homolog (mouse)0.070
si:ch211-272f3.4si:ch211-272f3.40.069
si:ch211-197h24.9si:ch211-197h24.90.069
wu:fc48e01wu:fc48e010.069
marcksbmyristoylated alanine rich protein kinase C substrate b0.068
kbpkif1-binding protein0.068
eif1beukaryotic translation initiation factor 1B0.068
LOC553527hypothetical protein LOC5535270.068
ilf2interleukin enhancer binding factor 20.067
atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.067
mtormechanistic target of rapamycin (serine/threonine kinase)0.066
si:ch211-232m7.1si:ch211-232m7.10.066
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
pblpebble0.912
exo84CG6095 gene product from transcript CG6095-RA0.820
S6kRPS6-p70-protein kinase0.762
beta-Specbeta Spectrin0.752
DetDeterin0.749
hydhyperplastic discs0.715
Rab11Rab-protein 110.694
Dhc64CDynein heavy chain 64C0.595
Lis-1Lissencephaly-10.579
aslasterless0.576
Eps-15Epidermal growth factor receptor pathway substrate clone 150.530
CG32038CG32038 gene product from transcript CG32038-RA0.514
poloCG12306 gene product from transcript CG12306-RA0.412
atlatlastin0.395
Rae1CG9862 gene product from transcript CG9862-RA0.392
Klp67AKinesin-like protein at 67A0.380
sec8CG2095 gene product from transcript CG2095-RA0.374
SMC2CG10212 gene product from transcript CG10212-RA0.353
diadiaphanous0.339
flrflare0.335
aspabnormal spindle0.329
pAbppolyA-binding protein0.325
cpacapping protein alpha0.315
Ras85DRas oncogene at 85D0.298
miminus0.293
Dap160Dynamin associated protein 1600.281
vibvibrator0.269
Klp3AKinesin-like protein at 3A0.259
Drp1Dynamin related protein 10.257
mfrmisfire0.244
brubrunelleschi0.231
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.230
chbchromosome bows0.228
alpha-Specalpha Spectrin0.220
Arp14DActin-related protein 14D0.213
htshu li tai shao0.206
ari-2ariadne 20.204
flwflapwing0.203
fwdfour wheel drive0.201
DlicDynein light intermediate chain0.196
serpserpentine0.192
rigrigor mortis0.181
CtBPC-terminal Binding Protein0.181
mib2mind bomb 20.174
eIF4G2eukaryotic translation initiation factor 4G20.170
ana3anastral spindle 30.167
TimpTissue inhibitor of metalloproteases0.165
snamasomething that sticks like glue0.164
CG2865CG2865 gene product from transcript CG2865-RA0.159
fwsfour way stop0.158
CG10267CG10267 gene product from transcript CG10267-RB0.151
Snr1Snf5-related 10.143
su(Hw)suppressor of Hairy wing0.140
vihvihar0.135
ChcClathrin heavy chain0.130
scrascraps0.129
ncdnon-claret disjunctional0.128
Fs(2)KetFemale sterile (2) Ketel0.124
Hsc70-5Heat shock protein cognate 50.122
BicDBicaudal D0.122
CycGCyclin G0.121
CG9572CG9572 gene product from transcript CG9572-RA0.119
Poc1Proteome of centrioles 10.116
stumpsCG31317 gene product from transcript CG31317-RC0.114
sinusinuous0.110
cazcabeza0.109
Hsp83Heat shock protein 830.109
Cdc37CG12019 gene product from transcript CG12019-RA0.109
HcfHost cell factor0.107
GaspCG10287 gene product from transcript CG10287-RB0.103
bnlbranchless0.102
Arp87CActin-related protein 87C0.100
MntCG13316 gene product from transcript CG13316-RD0.100
mtrmmatrimony0.100
Sas-4CG10061 gene product from transcript CG10061-RA0.099
WASpCG1520 gene product from transcript CG1520-RA0.097
chercheerio0.097
U2af38U2 small nuclear riboprotein auxiliary factor 380.095
bazbazooka0.094
ana2anastral spindle 20.094
sas-6spindle assembly abnormal 60.092
pelopelota0.092
HphHIF prolyl hydroxylase0.091
RfC4Replication factor C subunit 40.090
rheaCG6831 gene product from transcript CG6831-RA0.087
CG10722CG10722 gene product from transcript CG10722-RA0.086
swshort wing0.086
McrMacroglobulin complement-related0.086
MioMlx interactor0.082
MED1Mediator complex subunit 10.082
Mef2Myocyte enhancer factor 20.081
Pak3CG14895 gene product from transcript CG14895-RA0.080
eglegalitarian0.079
Pp4-19CProtein phosphatase 19C0.079
Klp10ACG1453 gene product from transcript CG1453-RA0.078
mldmolting defective0.076
Ten-mTenascin major0.076
par-1CG8201 gene product from transcript CG8201-RA0.076
Spc25CG7242 gene product from transcript CG7242-RA0.072
snkysneaky0.072
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RSC4Rsc4p0.877
RSC3Rsc3p0.851
SFH1Sfh1p0.783
RSC2Rsc2p0.764
NPL6Npl6p0.755
ARP7Arp7p0.742
ARP9Arp9p0.712
STH1Sth1p0.685
RSC6Rsc6p0.653
RSC8Rsc8p0.580
HHF1Hhf1p0.529
HTL1Htl1p0.528
BBC1Bbc1p0.508
BMH2Bmh2p0.480
RSC58Rsc58p0.472
RTT102Rtt102p0.434
MYO5Myo5p0.432
SSE1Sse1p0.414
YOL087Chypothetical protein0.398
CLB3Clb3p0.379
SUP35Sup35p0.374
RSC9Rsc9p0.343
YDJ1Ydj1p0.323
SRV2Srv2p0.307
BMH1Bmh1p0.295
KAR9Kar9p0.274
RSC1Rsc1p0.270
STU2Stu2p0.253
CDC10Cdc10p0.242
ASE1Ase1p0.224
SSK2Ssk2p0.217
CKS1Cks1p0.216
SSA1Ssa1p0.215
SSK1Ssk1p0.204
GBP2Gbp2p0.201
AQY2Aqy2p0.196
BOI1Boi1p0.194
DOA1Doa1p0.190
DBP5Dbp5p0.181
CDC12Cdc12p0.180
FPK1Fpk1p0.179
ZDS1Zds1p0.169
ABP1Abp1p0.160
CDC28Cdc28p0.157
ASF1Asf1p0.155
UBP2Ubp2p0.154
KIP1Kip1p0.152
NUP100Nup100p0.152
SSA4Ssa4p0.152
AIR1Air1p0.145
AIM3Aim3p0.138
TIF1Tif1p0.136
TEF1Tef1p0.136
MAD1Mad1p0.133
MYO3Myo3p0.128
STE7Ste7p0.125
PAF1Paf1p0.124
NUP170Nup170p0.120
SNF11Snf11p0.120
REB1Reb1p0.119
YPK1Ypk1p0.118
DYN1Dyn1p0.111
NET1Net1p0.110
AIM21Aim21p0.108
UBA1Uba1p0.108
CBF2Cbf2p0.104
KAP95Kap95p0.102
MEX67Mex67p0.102
CLU1Clu1p0.099
STI1Sti1p0.096
FAR11Far11p0.096
IMD3Imd3p0.094
DIA2Dia2p0.093
SVF1Svf1p0.090
BFA1Bfa1p0.088
FUN12Fun12p0.088
PSP2Psp2p0.087
ACT1Act1p0.085
BEM1Bem1p0.083
PTI1Pti1p0.082
HSC82Hsc82p0.080
TOP1Top1p0.079
RSC30Rsc30p0.078
UBP8Ubp8p0.078
RPM2Rpm2p0.078
SYF1Syf1p0.077
SHE3She3p0.077
SRP40Srp40p0.076
BSP1Bsp1p0.075
LIF1Lif1p0.074
URA7Ura7p0.073
SEC7Sec7p0.072
SET1Set1p0.072
CLB2Clb2p0.072
NUD1Nud1p0.071
MSN5Msn5p0.071
UBR1Ubr1p0.070
PBS2Pbs2p0.070
BDF1Bdf1p0.070
YEF3Yef3p0.068