The network for 'androgen receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

androgen receptor signaling pathway

Any series of molecular signals generated as a consequence of an androgen binding to its receptor.

NameDescriptionProbabilityFunc Analog Organism
CREBBPCREB binding protein0.981
CDK19cyclin-dependent kinase 190.971
MED1mediator complex subunit 10.894
MED10mediator complex subunit 100.861
MED15mediator complex subunit 150.853
EP300E1A binding protein p3000.807
ARandrogen receptor0.756
HDAC1histone deacetylase 10.744
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.720
TRIM39tripartite motif containing 390.651
MDM2Mdm2 p53 binding protein homolog (mouse)0.597
ARID1BAT rich interactive domain 1B (SWI1-like)0.559
NCOA2nuclear receptor coactivator 20.547
TP53tumor protein p530.539
SMAD2SMAD family member 20.511
DAXXdeath-domain associated protein0.465
MED29mediator complex subunit 290.452
ESR1estrogen receptor 10.447
SMAD3SMAD family member 30.433
MED12mediator complex subunit 120.403
CDK8cyclin-dependent kinase 80.388
ARID1AAT rich interactive domain 1A (SWI-like)0.346
MED24mediator complex subunit 240.284
SIN3ASIN3 homolog A, transcription regulator (yeast)0.278
SMAD9SMAD family member 90.266
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.239
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.235
NCOA3nuclear receptor coactivator 30.228
SKILSKI-like oncogene0.213
DDX5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.199
NCOR1nuclear receptor corepressor 10.197
HIPK2homeodomain interacting protein kinase 20.190
MED26mediator complex subunit 260.183
MBD1methyl-CpG binding domain protein 10.155
RNF5ring finger protein 50.154
MED6mediator complex subunit 60.154
RNF111ring finger protein 1110.147
SMAD1SMAD family member 10.147
SIRT1sirtuin 10.143
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.134
DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.127
MTA1metastasis associated 10.126
PMLpromyelocytic leukemia0.120
MED21mediator complex subunit 210.118
TOPORStopoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase0.114
SMAD4SMAD family member 40.110
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.106
SP1Sp1 transcription factor0.104
RNF114ring finger protein 1140.098
SPDEFSAM pointed domain containing ets transcription factor0.092
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.088
TRIM5tripartite motif containing 50.086
RNF11ring finger protein 110.085
HDAC2histone deacetylase 20.084
RXRAretinoid X receptor, alpha0.081
MED23mediator complex subunit 230.078
UBA1ubiquitin-like modifier activating enzyme 10.075
XIAPX-linked inhibitor of apoptosis0.065
MDM4Mdm4 p53 binding protein homolog (mouse)0.065
ZNF263zinc finger protein 2630.063
RB1retinoblastoma 10.063
HIPK1homeodomain interacting protein kinase 10.059
MTA3metastasis associated 1 family, member 30.056
TRIM27tripartite motif containing 270.055
BMPR1Bbone morphogenetic protein receptor, type IB0.054
NCOA1nuclear receptor coactivator 10.054
ESR2estrogen receptor 2 (ER beta)0.053
OTUB1OTU domain, ubiquitin aldehyde binding 10.052
HEYLhairy/enhancer-of-split related with YRPW motif-like0.050
ARIH2ariadne homolog 2 (Drosophila)0.046
HSPH1heat shock 105kDa/110kDa protein 10.046
SPOPspeckle-type POZ protein0.044
PIAS4protein inhibitor of activated STAT, 40.043
SKP1S-phase kinase-associated protein 10.043
SIAH1seven in absentia homolog 1 (Drosophila)0.043
FASFas (TNF receptor superfamily, member 6)0.042
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.042
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.041
TOP1topoisomerase (DNA) I0.041
ZNRF1zinc and ring finger 10.040
ZNF473zinc finger protein 4730.039
CHORDC1cysteine and histidine-rich domain (CHORD) containing 10.039
AKR1B1aldo-keto reductase family 1, member B1 (aldose reductase)0.038
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.038
CCNCcyclin C0.038
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.037
MED25mediator complex subunit 250.037
MYST2MYST histone acetyltransferase 20.037
TRIM43tripartite motif containing 430.037
MED20mediator complex subunit 200.035
MED28mediator complex subunit 280.034
LMO4LIM domain only 40.033
TRRAPtransformation/transcription domain-associated protein0.033
FOXO1forkhead box O10.033
PARP1poly (ADP-ribose) polymerase 10.033
HNRNPKheterogeneous nuclear ribonucleoprotein K0.032
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.032
KAT2BK(lysine) acetyltransferase 2B0.032
YY1YY1 transcription factor0.031
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.031
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cdkn1bcyclin-dependent kinase inhibitor 1B0.780
Arandrogen receptor0.466
Hdac2histone deacetylase 20.103
Arrb1arrestin, beta 10.077
Kiss1KiSS-1 metastasis-suppressor0.071
Tcfcp2l1transcription factor CP2-like 10.065
Sall4sal-like 4 (Drosophila)0.064
Ghrgrowth hormone receptor0.062
Fgfr2fibroblast growth factor receptor 20.061
Egfrepidermal growth factor receptor0.059
Sin3atranscriptional regulator, SIN3A (yeast)0.059
Ncoa6nuclear receptor coactivator 60.057
Esr1estrogen receptor 1 (alpha)0.057
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.056
Prlrprolactin receptor0.053
Iqcb1IQ calmodulin-binding motif containing 10.050
Fshrfollicle stimulating hormone receptor0.049
Sfrp2secreted frizzled-related protein 20.044
Ighmbp2immunoglobulin mu binding protein 20.042
Lhcgrluteinizing hormone/choriogonadotropin receptor0.042
Hsph1heat shock 105kDa/110kDa protein 10.041
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.040
Grb10growth factor receptor bound protein 100.037
Nos1nitric oxide synthase 1, neuronal0.035
Esr2estrogen receptor 2 (beta)0.035
Amhr2anti-Mullerian hormone type 2 receptor0.033
Pgrprogesterone receptor0.032
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.030
Polr2apolymerase (RNA) II (DNA directed) polypeptide A0.029
Apcadenomatosis polyposis coli0.028
Pmlpromyelocytic leukemia0.027
Leprleptin receptor0.026
Insrinsulin receptor0.026
Cav1caveolin 1, caveolae protein0.026
Ptenphosphatase and tensin homolog0.026
Arntlaryl hydrocarbon receptor nuclear translocator-like0.025
Mat2amethionine adenosyltransferase II, alpha0.024
Timp1tissue inhibitor of metalloproteinase 10.024
Ins2insulin II0.023
Clockcircadian locomotor output cycles kaput0.023
Rac1RAS-related C3 botulinum substrate 10.022
Pax8paired box gene 80.021
Hspa8heat shock protein 80.021
Egr2early growth response 20.021
Yy1YY1 transcription factor0.019
Med28mediator of RNA polymerase II transcription, subunit 28 homolog (yeast)0.018
Hoxa10homeobox A100.017
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.016
Ptpn11protein tyrosine phosphatase, non-receptor type 110.016
Adam17a disintegrin and metallopeptidase domain 170.016
Smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.016
Mta2metastasis-associated gene family, member 20.016
Cdkn1ccyclin-dependent kinase inhibitor 1C (P57)0.016
Nostrinnitric oxide synthase trafficker0.015
Foxo3forkhead box O30.015
Ythdc1YTH domain containing 10.015
Twist2twist homolog 2 (Drosophila)0.015
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.015
AxlAXL receptor tyrosine kinase0.015
Nos3nitric oxide synthase 3, endothelial cell0.014
Ahraryl-hydrocarbon receptor0.014
Ythdf3YTH domain family 30.014
Snw1SNW domain containing 10.014
Gpc3glypican 30.014
Atf2activating transcription factor 20.013
Asxl1additional sex combs like 1 (Drosophila)0.013
Esrrbestrogen related receptor, beta0.013
Drd2dopamine receptor D20.013
Hdac1histone deacetylase 10.013
Nodalnodal0.012
Cry1cryptochrome 1 (photolyase-like)0.012
Pcsk5proprotein convertase subtilisin/kexin type 50.011
Ppargperoxisome proliferator activated receptor gamma0.011
Cul3cullin 30.011
Lgals12lectin, galactose binding, soluble 120.011
Vdrvitamin D receptor0.011
Ncoa1nuclear receptor coactivator 10.011
Trp63transformation related protein 630.010
Arid2AT rich interactive domain 2 (ARID, RFX-like)0.010
Ins1insulin I0.010
Cul1cullin 10.010
Clk3CDC-like kinase 30.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism