The network for 'regulation of ras gtpase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of ras gtpase activity

Any process that modulates the activity of a GTPase of the Ras superfamily.

NameDescriptionProbabilityFunc Analog Organism
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.999
EGFRepidermal growth factor receptor0.999
PTK2PTK2 protein tyrosine kinase 20.995
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.990
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.988
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.981
SH3KBP1SH3-domain kinase binding protein 10.980
GRB7growth factor receptor-bound protein 70.971
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.957
MTORmechanistic target of rapamycin (serine/threonine kinase)0.941
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.928
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.928
HRASv-Ha-ras Harvey rat sarcoma viral oncogene homolog0.926
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.901
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.900
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.884
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.875
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.869
SFNstratifin0.840
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.839
S100A6S100 calcium binding protein A60.838
RHOAras homolog gene family, member A0.831
NCF2neutrophil cytosolic factor 20.829
ADRBK1adrenergic, beta, receptor kinase 10.737
ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)0.736
JUNjun proto-oncogene0.733
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.729
TRAF1TNF receptor-associated factor 10.717
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.695
S100BS100 calcium binding protein B0.692
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.689
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 110.672
SH3BP2SH3-domain binding protein 20.654
IGF1Rinsulin-like growth factor 1 receptor0.654
S100A8S100 calcium binding protein A80.652
SOS1son of sevenless homolog 1 (Drosophila)0.625
TSC1tuberous sclerosis 10.616
BCAR1breast cancer anti-estrogen resistance 10.590
MDM2Mdm2 p53 binding protein homolog (mouse)0.589
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.588
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.574
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.537
SH3RF1SH3 domain containing ring finger 10.534
MARK3MAP/microtubule affinity-regulating kinase 30.507
PVRL1poliovirus receptor-related 1 (herpesvirus entry mediator C)0.507
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.495
TSC2tuberous sclerosis 20.479
NTRK1neurotrophic tyrosine kinase, receptor, type 10.472
ABI1abl-interactor 10.460
FOSFBJ murine osteosarcoma viral oncogene homolog0.441
S100A11S100 calcium binding protein A110.435
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.408
ZMYND11zinc finger, MYND-type containing 110.408
FMNL1formin-like 10.408
METmet proto-oncogene (hepatocyte growth factor receptor)0.398
CCR5chemokine (C-C motif) receptor 50.395
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.388
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.384
RASSF5Ras association (RalGDS/AF-6) domain family member 50.375
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.372
ATP7AATPase, Cu++ transporting, alpha polypeptide0.368
RACGAP1Rac GTPase activating protein 10.360
RHOCras homolog gene family, member C0.355
PKN3protein kinase N30.348
HIPK2homeodomain interacting protein kinase 20.333
FAM65Afamily with sequence similarity 65, member A0.303
DOCK1dedicator of cytokinesis 10.301
ABL2v-abl Abelson murine leukemia viral oncogene homolog 20.300
GABARAPL1GABA(A) receptor-associated protein like 10.297
TNFtumor necrosis factor0.291
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.275
ANXA2annexin A20.274
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.267
CNKSR2connector enhancer of kinase suppressor of Ras 20.266
RPTORregulatory associated protein of MTOR, complex 10.264
RALBP1ralA binding protein 10.254
S100A9S100 calcium binding protein A90.251
DSPdesmoplakin0.246
KIAA0930KIAA09300.245
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.242
S100A4S100 calcium binding protein A40.241
NCK1NCK adaptor protein 10.240
CCL2chemokine (C-C motif) ligand 20.239
TRAF5TNF receptor-associated factor 50.234
GRB2growth factor receptor-bound protein 20.230
AKT1S1AKT1 substrate 1 (proline-rich)0.220
KRT14keratin 140.211
NCKAP1NCK-associated protein 10.208
CSNK1G2casein kinase 1, gamma 20.203
CAPGcapping protein (actin filament), gelsolin-like0.203
BBS10Bardet-Biedl syndrome 100.201
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.199
EPHA7EPH receptor A70.196
EFNA5ephrin-A50.192
JUNBjun B proto-oncogene0.188
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.187
RHEBRas homolog enriched in brain0.180
MPRIPmyosin phosphatase Rho interacting protein0.178
RND1Rho family GTPase 10.175
ANK1ankyrin 1, erythrocytic0.172
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
let-60Protein LET-600.206
sup-17Protein SUP-170.169
CELE_F47G4.4Protein F47G4.40.144
sem-5Protein SEM-50.136
C11E4.6Protein C11E4.60.130
rgl-1Protein RGL-10.126
rig-6Protein RIG-60.126
zfp-3Protein ZFP-30.118
snf-1Protein SNF-10.107
zfp-1Protein ZFP-10.105
R10E12.2Protein R10E12.20.084
bet-2Protein BET-20.072
abl-1Protein ABL-10.071
unc-71Protein UNC-710.068
mpk-1Protein MPK-10.068
sym-4Protein SYM-40.067
ptp-1Protein PTP-10.062
CELE_W07A8.2Protein W07A8.20.052
ajm-1Protein AJM-10.042
T04F8.6Protein T04F8.60.041
cdh-3Protein CDH-30.041
afd-1Protein AFD-10.039
zoo-1Protein ZOO-10.039
par-3Protein PAR-30.037
ddr-2Protein DDR-20.036
gap-2Protein GAP-20.034
plc-3Protein PLC-30.033
mrck-1Protein MRCK-10.033
Y55F3BR.8Protein Y55F3BR.80.031
shn-1Protein SHN-10.031
lag-1Protein LAG-10.029
ape-1Protein APE-10.029
R90.1Protein R90.10.029
CELE_T10D4.6Protein T10D4.60.029
lir-1Protein LIR-10.028
smp-1Protein SMP-10.027
sma-6Protein SMA-60.027
unc-26Protein UNC-260.027
itr-1Protein ITR-10.026
gei-8Protein GEI-80.026
rme-4Protein RME-40.026
madf-5Protein MADF-50.025
etr-1Protein ETR-10.025
gar-3Protein GAR-30.024
grk-1Protein GRK-10.024
rab-5Protein RAB-50.024
wdr-23Protein WDR-230.024
magu-3Protein MAGU-30.024
lin-48Protein LIN-480.023
gei-4Protein GEI-40.023
magi-1Protein MAGI-10.023
unc-41Protein UNC-410.022
CELE_F52E1.13Protein F52E1.130.022
C06G1.5Protein C06G1.50.022
rnp-8Protein RNP-80.022
sma-9Protein SMA-90.021
C41D11.4Protein C41D11.40.021
R11A8.7Protein R11A8.70.021
sax-3Protein SAX-30.020
eor-1Protein EOR-10.020
T23F2.2Protein T23F2.20.020
CELE_F53C11.5Protein F53C11.50.020
F22D3.2Protein F22D3.20.020
nhr-45Protein NHR-450.019
pak-1Protein PAK-10.019
daf-19Protein DAF-190.019
cgef-1Protein CGEF-10.019
tat-1Protein TAT-10.017
egl-18Protein EGL-180.017
frm-8Protein FRM-80.017
ina-1Protein INA-10.017
pqn-39Protein PQN-390.017
F16A11.1Protein F16A11.10.017
lin-45Protein LIN-450.017
frm-10Protein FRM-100.017
CELE_R09F10.3Protein R09F10.30.017
lfi-1Protein LFI-10.016
D2085.5Protein D2085.50.016
C27H2.2Protein C27H2.20.016
sel-8Protein SEL-80.016
mig-5Protein MIG-50.016
unc-45Protein UNC-450.016
cyld-1Protein CYLD-10.016
rgs-7Protein RGS-70.016
F07C6.4Protein F07C6.40.016
fhod-1Protein FHOD-10.016
cdh-9Protein CDH-90.016
kin-25Protein KIN-250.015
C53D5.1Protein C53D5.10.015
egrh-1Protein EGRH-10.015
stau-1Protein STAU-10.015
git-1Protein GIT-10.015
cah-6Protein CAH-60.015
pry-1Protein PRY-10.015
elt-6Protein ELT-60.015
tag-303Protein TAG-3030.015
cam-1Protein CAM-10.015
dpf-3Protein DPF-30.015
nep-12Protein NEP-120.015
mtm-3Protein MTM-30.014
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.052
tpm4tropomyosin 40.045
rtcd1RNA terminal phosphate cyclase domain 10.042
plxnb2aplexin b2a0.041
card9caspase recruitment domain family, member 90.037
cnn2calponin 20.032
adrb2aadrenergic receptor, beta 2a0.029
anxa2aannexin A2a0.029
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.029
pitx3paired-like homeodomain transcription factor 30.026
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.026
gna12guanine nucleotide binding protein (G protein) alpha 120.026
s100a10bS100 calcium binding protein A10b0.025
vangl2vang-like 2 (van gogh, Drosophila)0.025
mat2amethionine adenosyltransferase II, alpha0.025
abcf2ATP-binding cassette, sub-family F (GCN20), member 20.025
si:dkey-228g21.4si:dkey-228g21.40.024
cltcaclathrin, heavy polypeptide a (Hc)0.024
stmn2bstathmin-like 2b0.023
kbpkif1-binding protein0.023
mtpmicrosomal triglyceride transfer protein0.023
scinlbscinderin like b0.022
si:ch211-195h23.3si:ch211-195h23.30.022
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.021
stau1staufen, RNA binding protein, homolog 1 (Drosophila)0.021
gnao1aguanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a0.021
gna13bguanine nucleotide binding protein (G protein), alpha 13b0.021
casz1castor zinc finger 10.021
fem1cfem-1 homolog c (C.elegans)0.021
xpo4exportin 40.021
aif1lallograft inflammatory factor 1-like0.021
zbtb4zinc finger and BTB domain containing 40.020
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.020
ahnakAHNAK nucleoprotein0.020
ppargperoxisome proliferator activated receptor gamma0.020
iqgap1IQ motif containing GTPase activating protein 10.020
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.020
LOC565256similar to Metabotropic glutamate receptor 3 precursor (mGluR3)0.020
icnictacalcin0.020
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.020
sb:cb730sb:cb7300.020
gnaiaguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a0.019
foxa2forkhead box A20.019
adrb2badrenergic receptor, beta 2b0.019
rps6ka3aribosomal protein S6 kinase, polypeptide 3a0.019
rxrbbretinoid x receptor, beta b0.019
whsc1Wolf-Hirschhorn syndrome candidate 10.018
s100v2S100 calcium binding protein V20.018
pvrl1bpoliovirus receptor-related 1b0.018
cftrcystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)0.018
stau2staufen, RNA binding protein, homolog 2 (Drosophila)0.018
mycbp2MYC binding protein 20.018
acvr1bactivin A receptor, type IB0.018
diaph2diaphanous homolog 2 (Drosophila)0.018
pobpartial optokinetic response b0.018
msnamoesin a0.018
dock1dedicator of cytokinesis 10.018
ela2elastase 20.018
m17IL-6 subfamily cytokine M170.018
ankrd6ankyrin repeat domain 60.018
zgc:85727zgc:857270.018
ap2a1adaptor-related protein complex 2, alpha 1 subunit0.018
tsc2tuberous sclerosis 20.017
zeb1zinc finger E-box binding homeobox 10.017
LOC100535549cytoplasmic polyadenylation element-binding protein 4-like0.017
tm9sf2transmembrane 9 superfamily member 20.017
huwe1HECT, UBA and WWE domain containing 10.017
clic1chloride intracellular channel 10.017
LOC565839tumor necrosis factor alpha-induced protein 2-like0.017
ints9integrator complex subunit 90.017
eya2eyes absent homolog 2 (Drosophila)0.017
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.017
akt2v-akt murine thymoma viral oncogene homolog 20.017
optcopticin0.017
il11rainterleukin 11 receptor, alpha0.017
srisorcin0.017
ldb2aLIM-domain binding factor 2a0.017
copebcore promoter element binding protein0.017
phf21aPHD finger protein 21A0.017
odc1ornithine decarboxylase 10.017
zgc:112986zgc:1129860.017
zgc:56466zgc:564660.017
atf3activating transcription factor 30.016
slc12a10.2solute carrier family 12 (sodium/potassium/chloride transporters), member 10.20.016
foxi2forkhead box I20.016
bactin2bactin20.016
gria4bglutamate receptor, ionotropic, AMPA 4b0.016
rcn1reticulocalbin 1, EF-hand calcium binding domain0.016
slc6a9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.016
pacsin3protein kinase C and casein kinase substrate in neurons 30.016
ssbp3asingle stranded DNA binding protein 3a0.016
nrarpanotch-regulated ankyrin repeat protein a0.016
trpa1btransient receptor potential cation channel, subfamily A, member 1b0.016
arpc1aactin related protein 2/3 complex, subunit 1A0.016
zgc:153460zgc:1534600.016
hif1anhypoxia-inducible factor 1, alpha subunit inhibitor0.016
zgc:100838zgc:1008380.016
march6membrane-associated ring finger (C3HC4) 60.016
zgc:101724zgc:1017240.016
si:ch211-160j6.2si:ch211-160j6.20.016
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
smosmoothened0.817
Pi3K92ECG4141 gene product from transcript CG4141-RB0.814
pod1CG4532 gene product from transcript CG4532-RF0.742
SosSon of sevenless0.603
RhebCG1081 gene product from transcript CG1081-RA0.582
drkdownstream of receptor kinase0.517
trioCG18214 gene product from transcript CG18214-RA0.391
rokRho-kinase0.278
dosdaughter of sevenless0.274
PtenCG5671 gene product from transcript CG5671-RB0.262
CG6509CG6509 gene product from transcript CG6509-RB0.255
staistathmin0.228
PknProtein kinase related to protein kinase N0.227
Fak56DFocal Adhesion Kinase0.226
mbcmyoblast city0.181
synjsynaptojanin0.177
lgslegless0.173
Stat92ESignal-transducer and activator of transcription protein at 92E0.149
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.131
rlrolled0.130
Mkp3Mitogen-activated protein kinase phosphatase 30.125
ApcAPC-like0.125
Arf79FADP ribosylation factor 79F0.122
pucpuckered0.121
kenken and barbie0.120
ttktramtrack0.119
htlheartless0.111
WnkCG7177 gene product from transcript CG7177-RA0.107
flwflapwing0.103
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.103
p120ctnAdherens junction protein p1200.102
Hnf4Hepatocyte nuclear factor 40.099
mbtmushroom bodies tiny0.096
RhoGAP93BCG3421 gene product from transcript CG3421-RA0.095
Ced-12CG5336 gene product from transcript CG5336-RA0.094
bazbazooka0.092
sizschizo0.088
MadMothers against dpp0.087
AbiAbelson interacting protein0.086
Pak3CG14895 gene product from transcript CG14895-RA0.085
auxauxillin0.083
Su(H)Suppressor of Hairless0.082
kuzkuzbanian0.080
PTP-ERProtein tyrosine phosphatase-ERK/Enhancer of Ras10.079
stgstring0.078
NaCP60ENa channel protein 60E0.076
maskmultiple ankyrin repeats single KH domain0.075
rapretina aberrant in pattern0.073
yrtyurt0.071
CG11851CG11851 gene product from transcript CG11851-RA0.071
tutlturtle0.068
LarLeukocyte-antigen-related-like0.066
neuroliginCG13772 gene product from transcript CG13772-RA0.065
simasimilar0.064
mopmyopic0.064
CG8334CG8334 gene product from transcript CG8334-RA0.063
thsthisbe0.061
MtlMig-2-like0.061
PtpmegCG1228 gene product from transcript CG1228-RD0.060
CG4853CG4853 gene product from transcript CG4853-RA0.059
CG32772CG32772 gene product from transcript CG32772-RC0.059
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.058
MerMerlin0.057
Prp31CG6876 gene product from transcript CG6876-RA0.056
Rip11Rab11 interacting protein0.056
Drl-2Derailed 20.056
Wnt5Wnt oncogene analog 50.054
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.053
Ras64BRas oncogene at 64B0.053
enaenabled0.052
CG7158CG7158 gene product from transcript CG7158-RA0.051
CG8155CG8155 gene product from transcript CG8155-RA0.051
Zasp66Z band alternatively spliced PDZ-motif protein 660.051
CG10631CG10631 gene product from transcript CG10631-RA0.050
Akt1CG4006 gene product from transcript CG4006-RA0.050
piepineapple eye0.050
didumdilute class unconventional myosin0.050
RalaRas-related protein0.049
l(2)k05819lethal (2) k058190.048
LnkCG17367 gene product from transcript CG17367-RC0.048
alpha-Man-IIalpha Mannosidase II0.048
LIMK1LIM-kinase10.048
Sin3ACG8815 gene product from transcript CG8815-RC0.048
dmdiminutive0.047
CG4552CG4552 gene product from transcript CG4552-RA0.047
Vps16AVacuolar protein sorting 16A0.047
S6kRPS6-p70-protein kinase0.047
SmoxSmad on X0.047
EphrinCG1862 gene product from transcript CG1862-RA0.047
ctaconcertina0.046
Pk61CProtein kinase 61C0.046
SCARCG4636 gene product from transcript CG4636-RA0.046
phlpole hole0.046
plexBplexin B0.045
vavCG7893 gene product from transcript CG7893-RB0.045
cnocanoe0.045
rictorrapamycin-insensitive companion of Tor0.045
gclgerm cell-less0.045
CG11033CG11033 gene product from transcript CG11033-RB0.045
CG5798CG5798 gene product from transcript CG5798-RA0.044
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A1.000
Epha4Eph receptor A40.999
Efnb2ephrin B20.998
Ephb2Eph receptor B20.997
Itsn1intersectin 1 (SH3 domain protein 1A)0.989
Retret proto-oncogene0.970
Ntf3neurotrophin 30.955
Rac1RAS-related C3 botulinum substrate 10.927
Sox10SRY-box containing gene 100.926
Plcg1phospholipase C, gamma 10.924
BrafBraf transforming gene0.920
Adrb1adrenergic receptor, beta 10.910
Plxnb1plexin B10.909
Apcadenomatosis polyposis coli0.906
Grb2growth factor receptor bound protein 20.885
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.884
Leprleptin receptor0.864
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.859
Ephb3Eph receptor B30.852
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.851
Shc1src homology 2 domain-containing transforming protein C10.827
CblCasitas B-lineage lymphoma0.823
Ccl2chemokine (C-C motif) ligand 20.772
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.770
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.765
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.763
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.698
Klklotho0.696
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.693
Mapkap1mitogen-activated protein kinase associated protein 10.690
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.689
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.677
Ly6hlymphocyte antigen 6 complex, locus H0.667
Rtknrhotekin0.661
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.642
Eps15epidermal growth factor receptor pathway substrate 150.621
Efna1ephrin A10.616
Plxna1plexin A10.607
Sema6dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.594
Arrb2arrestin, beta 20.590
Mtormechanistic target of rapamycin (serine/threonine kinase)0.588
FosFBJ osteosarcoma oncogene0.584
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.582
Vav3vav 3 oncogene0.572
Cd44CD44 antigen0.565
Chrm1cholinergic receptor, muscarinic 1, CNS0.563
Git1G protein-coupled receptor kinase-interactor 10.559
Tnks1bp1tankyrase 1 binding protein 10.548
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.543
Hdac7histone deacetylase 70.536
Vav2vav 2 oncogene0.535
Arhgef12Rho guanine nucleotide exchange factor (GEF) 120.525
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.521
Spry4sprouty homolog 4 (Drosophila)0.496
Mmp15matrix metallopeptidase 150.493
Adora2aadenosine A2a receptor0.480
Pnpla2patatin-like phospholipase domain containing 20.479
Pde1bphosphodiesterase 1B, Ca2+-calmodulin dependent0.477
Spry2sprouty homolog 2 (Drosophila)0.471
Vav1vav 1 oncogene0.469
Prkcbprotein kinase C, beta0.467
Stxbp3asyntaxin binding protein 3A0.466
Plxna3plexin A30.462
Ltblymphotoxin B0.459
Nf2neurofibromatosis 20.451
Ror1receptor tyrosine kinase-like orphan receptor 10.449
Pou3f3POU domain, class 3, transcription factor 30.449
Ctnnb1catenin (cadherin associated protein), beta 10.448
Jupjunction plakoglobin0.440
Arhgap21Rho GTPase activating protein 210.433
Rasgrp1RAS guanyl releasing protein 10.421
Cdh6cadherin 60.418
Ptpn11protein tyrosine phosphatase, non-receptor type 110.409
Adrbk1adrenergic receptor kinase, beta 10.399
Irf5interferon regulatory factor 50.395
Fzd1frizzled homolog 1 (Drosophila)0.394
Sh3rf1SH3 domain containing ring finger 10.385
Sh2d3cSH2 domain containing 3C0.378
Prkceprotein kinase C, epsilon0.359
Grid1glutamate receptor, ionotropic, delta 10.358
Adcy4adenylate cyclase 40.358
Ppargperoxisome proliferator activated receptor gamma0.354
Cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.353
Cttncortactin0.344
Nf1neurofibromatosis 10.343
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.343
Sh3pxd2aSH3 and PX domains 2A0.343
Mark4MAP/microtubule affinity-regulating kinase 40.337
Ptk2PTK2 protein tyrosine kinase 20.335
SrcRous sarcoma oncogene0.332
Gli3GLI-Kruppel family member GLI30.330
Dock1dedicator of cytokinesis 10.328
Sema5asema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A0.328
Rhobras homolog gene family, member B0.323
Nck2non-catalytic region of tyrosine kinase adaptor protein 20.319
Elmo1engulfment and cell motility 1, ced-12 homolog (C. elegans)0.319
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.316
Pou3f2POU domain, class 3, transcription factor 20.312
Kcnk2potassium channel, subfamily K, member 20.310
Esrrbestrogen related receptor, beta0.310
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Arpc3actin related protein 2/3 complex, subunit 30.116
Nptnneuroplastin0.103
Epas1endothelial PAS domain protein 10.086
Dlg3discs, large homolog 3 (Drosophila)0.079
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.074
Anxa2annexin A20.066
Smg5Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)0.059
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.058
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.048
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.043
Sept10septin 100.042
Exoc5exocyst complex component 50.042
Zfp260zinc finger protein 2600.039
Pls3plastin 3 (T-isoform)0.037
TekTEK tyrosine kinase, endothelial0.037
Tle4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)0.036
Pja2praja 2, RING-H2 motif containing0.035
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.032
Klf6Kruppel-like factor 60.031
Cyb5r4cytochrome b5 reductase 40.030
Clcn2chloride channel 20.030
Dync1h1dynein cytoplasmic 1 heavy chain 10.029
Jak2Janus kinase 20.029
Ptafrplatelet-activating factor receptor0.029
Pld2phospholipase D20.028
Cyth1cytohesin 10.027
Tgfbr2transforming growth factor, beta receptor II0.027
Fam108a1family with sequence similarity 108, member A10.027
Bin2bridging integrator 20.027
Map2microtubule-associated protein 20.027
Picalmphosphatidylinositol binding clathrin assembly protein0.027
Sdc3syndecan 30.026
Capn2calpain 20.026
Trappc6btrafficking protein particle complex 6B0.026
Apbb1ipamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein0.026
Nckap1NCK-associated protein 10.026
Rab1bRAB1B, member RAS oncogene family0.026
Mllt1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.026
Ptprsprotein tyrosine phosphatase, receptor type, S0.026
Git1G protein-coupled receptor kinase interacting ArfGAP 10.025
Rap1bRAP1B, member of RAS oncogene family0.025
Scamp1secretory carrier membrane protein 10.025
Prkchprotein kinase C, eta0.025
Plxnd1plexin D10.025
Klf4Kruppel-like factor 4 (gut)0.024
Gria2glutamate receptor, ionotropic, AMPA 20.024
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.024
Hk1hexokinase 10.024
Stxbp5syntaxin binding protein 5 (tomosyn)0.023
LOC691920similar to kinesin-like motor protein C20orf230.023
Gnai1guanine nucleotide binding protein (G protein), alpha inhibiting 10.023
Pde2aphosphodiesterase 2A, cGMP-stimulated0.023
Dok1docking protein 10.023
Zfp36zinc finger protein 360.023
Gpr116G protein-coupled receptor 1160.023
Utrnutrophin0.022
Clcn7chloride channel 70.022
Btg2BTG family, member 20.022
Caskcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.021
Ptpn18protein tyrosine phosphatase, non-receptor type 180.021
Macf1microtubule-actin crosslinking factor 10.021
Acvrl1activin A receptor type II-like 10.021
Inpp5dinositol polyphosphate-5-phosphatase D0.021
Akap1A kinase (PRKA) anchor protein 10.021
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.021
S100a4S100 calcium-binding protein A40.021
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.020
Rab3il1RAB3A interacting protein (rabin3)-like 10.020
Dock9dedicator of cytokinesis 90.020
Foxp1forkhead box P10.020
Pik3r3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.020
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.020
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.020
Ntn1netrin 10.020
Slit3slit homolog 3 (Drosophila)0.020
Itpr1inositol 1,4,5-triphosphate receptor, type 10.020
Sumo1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.020
Itpr2inositol 1,4,5-triphosphate receptor, type 20.019
Cx3cl1chemokine (C-X3-C motif) ligand 10.019
Vsnl1visinin-like 10.019
Lphn2latrophilin 20.019
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.019
Add3adducin 3 (gamma)0.019
LOC313672kazrin0.019
Lzts2leucine zipper, putative tumor suppressor 20.019
Adcy6adenylate cyclase 60.018
Hivep2human immunodeficiency virus type I enhancer binding protein 20.018
Unc13dunc-13 homolog D (C. elegans)0.018
Pcnxl3pecanex-like 3 (Drosophila)0.018
Ppp1r13bprotein phosphatase 1, regulatory (inhibitor) subunit 13B0.018
Plcg1phospholipase C, gamma 10.018
Sbf1SET binding factor 10.018
Bcl6bB-cell CLL/lymphoma 6, member B (zinc finger protein)0.018
Dapk3death-associated protein kinase 30.018
Rock2Rho-associated coiled-coil containing protein kinase 20.018
Fgd5FYVE, RhoGEF and PH domain containing 50.018
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.018
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.018
Sh2d3cSH2 domain containing 3C0.017
G3bp2GTPase activating protein (SH3 domain) binding protein 20.017
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
GYL1Gyl1p0.491
ROM2Rom2p0.278
STE11Ste11p0.236
MKK1Mkk1p0.222
BEM3Bem3p0.186
BET3Bet3p0.176
RHO1Rho1p0.153
MDS3Mds3p0.135
TRS65Trs65p0.104
PKC1Pkc1p0.102
STE5Ste5p0.100
GDI1Gdi1p0.099
CDC24Cdc24p0.098
FYV8Fyv8p0.082
CRM1Crm1p0.081
IRA1Ira1p0.078
ACK1Ack1p0.075
SEC3Sec3p0.067
TSC11Tsc11p0.066
SAC7Sac7p0.062
KEL1Kel1p0.058
KOG1Kog1p0.058
YIL055Chypothetical protein0.055
SEC15Sec15p0.055
MNN9Mnn9p0.052
ATG20Atg20p0.050
TCO89Tco89p0.050
SLG1Slg1p0.048
TCA17Tca17p0.047
SLT2Slt2p0.046
SSK2Ssk2p0.045
SPA2Spa2p0.045
GIC2Gic2p0.042
RGD1Rgd1p0.040
YPT53Ypt53p0.039
GPB2Gpb2p0.039
GDS1Gds1p0.038
VPS15Vps15p0.037
SRP54Srp54p0.037
YDR186Chypothetical protein0.033
PRS2Prs2p0.032
PTP2Ptp2p0.032
NVJ1Nvj1p0.032
FAA2Faa2p0.031
SEC2Sec2p0.031
SSK1Ssk1p0.030
VPS35Vps35p0.030
YOL087Chypothetical protein0.030
BST1Bst1p0.030
FMS1Fms1p0.029
MON1Mon1p0.028
CHS1Chs1p0.028
FUS2Fus2p0.027
YPL066Whypothetical protein0.026
TLG2Tlg2p0.026
KAP114Kap114p0.026
BEM2Bem2p0.026
TAO3Tao3p0.026
YLR264C-Ahypothetical protein0.025
TUS1Tus1p0.025
SRD1Srd1p0.024
AVO1Avo1p0.024
YIP3Yip3p0.024
CMK2Cmk2p0.024
SKM1Skm1p0.024
CDC12Cdc12p0.023
CSF1Csf1p0.023
TAM41Tam41p0.023
BIT61Bit61p0.023
SLH1Slh1p0.023
AKL1Akl1p0.023
HSV2Hsv2p0.023
BNI1Bni1p0.022
YLR162Whypothetical protein0.022
URA3Ura3p0.022
SLM1Slm1p0.022
PPH21Pph21p0.022
TOM1Tom1p0.022
BPT1Bpt1p0.022
CDC25Cdc25p0.022
TRS85Trs85p0.022
LEU2Leu2p0.022
UBP5Ubp5p0.022
SSK22Ssk22p0.022
BEM4Bem4p0.021
ENT1Ent1p0.021
RGD2Rgd2p0.021
BUD8Bud8p0.021
BCK1Bck1p0.021
SPR6Spr6p0.021
YGR126Whypothetical protein0.021
ARG8Arg8p0.021
YOL038C-Ahypothetical protein0.021
VPS41Vps41p0.020
CUP1-1Cup1-1p0.020
BUL1Bul1p0.020
HYP2Hyp2p0.020
ARP10Arp10p0.020
SEN54Sen54p0.020
MSB3Msb3p0.020