The network for 'positive regulation of hydrolase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of hydrolase activity

Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.

NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.997
CASP8caspase 8, apoptosis-related cysteine peptidase0.996
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.996
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.995
MDM2Mdm2 p53 binding protein homolog (mouse)0.992
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.990
GRB2growth factor receptor-bound protein 20.988
FASLGFas ligand (TNF superfamily, member 6)0.985
BCAR1breast cancer anti-estrogen resistance 10.984
ARRB1arrestin, beta 10.982
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.980
FGFR2fibroblast growth factor receptor 20.979
BCL2L11BCL2-like 11 (apoptosis facilitator)0.970
FASFas (TNF receptor superfamily, member 6)0.970
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.956
SMAD4SMAD family member 40.956
PTK2PTK2 protein tyrosine kinase 20.927
FN1fibronectin 10.927
CASP10caspase 10, apoptosis-related cysteine peptidase0.920
SFNstratifin0.912
BCL2B-cell CLL/lymphoma 20.911
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.900
EGFRepidermal growth factor receptor0.899
PTENphosphatase and tensin homolog0.897
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.882
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.873
FYNFYN oncogene related to SRC, FGR, YES0.870
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.860
TSC2tuberous sclerosis 20.857
PLCG1phospholipase C, gamma 10.855
BAXBCL2-associated X protein0.847
SKILSKI-like oncogene0.847
S100A6S100 calcium binding protein A60.846
CFLARCASP8 and FADD-like apoptosis regulator0.836
MAPK14mitogen-activated protein kinase 140.833
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.832
SMAD3SMAD family member 30.826
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.815
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.813
PYCARDPYD and CARD domain containing0.802
CASP3caspase 3, apoptosis-related cysteine peptidase0.800
RIN3Ras and Rab interactor 30.784
RHOAras homolog gene family, member A0.775
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.767
BBS10Bardet-Biedl syndrome 100.759
BCL2L1BCL2-like 10.746
SMN1survival of motor neuron 1, telomeric0.742
VEGFAvascular endothelial growth factor A0.742
PSEN1presenilin 10.736
NCK1NCK adaptor protein 10.734
ARRB2arrestin, beta 20.714
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.701
ABI1abl-interactor 10.701
JUNjun proto-oncogene0.694
S100A11S100 calcium binding protein A110.694
NRP1neuropilin 10.689
FMR1fragile X mental retardation 10.688
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.681
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.680
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.680
BIDBH3 interacting domain death agonist0.672
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.666
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.660
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.658
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.657
FKBP4FK506 binding protein 4, 59kDa0.646
S100BS100 calcium binding protein B0.638
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.635
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.629
LAMTOR1late endosomal/lysosomal adaptor, MAPK and MTOR activator 10.628
FHL2four and a half LIM domains 20.627
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.625
GAS7growth arrest-specific 70.620
BADBCL2-associated agonist of cell death0.619
CCR5chemokine (C-C motif) receptor 50.609
NCLnucleolin0.606
RAD21RAD21 homolog (S. pombe)0.606
FGF1fibroblast growth factor 1 (acidic)0.604
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.599
LAMTOR2late endosomal/lysosomal adaptor, MAPK and MTOR activator 20.590
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.584
EP300E1A binding protein p3000.583
CASP2caspase 2, apoptosis-related cysteine peptidase0.582
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.574
MAPK1mitogen-activated protein kinase 10.574
CASP9caspase 9, apoptosis-related cysteine peptidase0.574
ENGendoglin0.574
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.570
BMP2bone morphogenetic protein 20.567
TRAF1TNF receptor-associated factor 10.564
CCT5chaperonin containing TCP1, subunit 5 (epsilon)0.562
RACGAP1Rac GTPase activating protein 10.559
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 110.554
RXRAretinoid X receptor, alpha0.554
S100A1S100 calcium binding protein A10.554
PLECplectin0.549
RARAretinoic acid receptor, alpha0.549
TGFB1transforming growth factor, beta 10.547
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
mpk-1Protein MPK-10.170
gei-4Protein GEI-40.127
sem-5Protein SEM-50.094
goa-1Protein GOA-10.094
let-60Protein LET-600.089
cyc-1Protein CYC-10.086
pdi-3Protein PDI-30.082
nck-1Protein NCK-10.075
sli-1Protein SLI-10.070
unc-26Protein UNC-260.066
flh-2Protein FLH-20.062
ant-1.1Protein ANT-1.10.061
rig-6Protein RIG-60.060
mbk-1Protein MBK-10.060
bet-2Protein BET-20.058
C11H1.3Protein C11H1.30.055
cgef-2Protein CGEF-20.052
nurf-1Protein NURF-10.052
rhgf-2Protein RHGF-20.049
sma-9Protein SMA-90.047
lag-1Protein LAG-10.046
ced-9Protein CED-90.046
rps-5Protein RPS-50.046
unc-71Protein UNC-710.045
cks-1Protein CKS-10.043
lin-45Protein LIN-450.041
rbg-1Protein RBG-10.041
npp-9Protein NPP-90.041
rgl-1Protein RGL-10.041
bar-1Protein BAR-10.040
atg-11Protein ATG-110.040
abl-1Protein ABL-10.039
cin-4Protein CIN-40.039
smp-1Protein SMP-10.039
pek-1Protein PEK-10.038
fhod-1Protein FHOD-10.038
dars-1Protein DARS-10.038
C07B5.4Protein C07B5.40.037
afd-1Protein AFD-10.036
rme-4Protein RME-40.035
rla-0Protein RLA-00.035
sur-2Protein SUR-20.035
tag-343Protein TAG-3430.034
tmc-2Protein TMC-20.034
cdc-48.2Protein CDC-48.20.034
hsp-1Protein HSP-10.033
lim-9Protein LIM-90.033
egl-18Protein EGL-180.033
mat-3Protein MAT-30.032
ptp-4Protein PTP-40.031
T28B11.1Protein T28B11.10.031
lmp-2Protein LMP-20.031
uaf-1Protein UAF-10.031
CELE_Y60A3A.9Protein Y60A3A.90.030
T21B6.3Protein T21B6.30.030
mtm-3Protein MTM-30.030
rab-5Protein RAB-50.029
ostb-1Protein OSTB-10.029
pde-4Protein PDE-40.029
egl-13Protein EGL-130.028
ess-2Protein ESS-20.028
rpl-12Protein RPL-120.028
CELE_K08E7.6Protein K08E7.60.027
aha-1Protein AHA-10.027
rpn-1Protein RPN-10.027
W03G9.2Protein W03G9.20.027
rsbp-1Protein RSBP-10.027
sup-17Protein SUP-170.027
rpm-1Protein RPM-10.027
jnk-1Protein JNK-10.027
let-268Protein LET-2680.027
gar-3Protein GAR-30.027
egrh-1Protein EGRH-10.027
C06G1.5Protein C06G1.50.026
sad-1Protein SAD-10.026
sma-1Protein SMA-10.026
dpy-27Protein DPY-270.026
plc-1Protein PLC-10.026
mei-1Protein MEI-10.026
F28B3.1Protein F28B3.10.026
svh-2Protein SVH-20.026
glb-6Protein GLB-60.026
sta-1Protein STA-10.025
T23B12.6Protein T23B12.60.025
vrk-1Protein VRK-10.025
snt-4Protein SNT-40.025
rpt-1Protein RPT-10.025
toca-1Protein TOCA-10.025
Y77E11A.1Protein Y77E11A.10.025
miro-1Protein MIRO-10.025
dnj-25Protein DNJ-250.025
ahcy-1Protein AHCY-10.024
T20D3.11Protein T20D3.110.024
cct-6Protein CCT-60.024
K10C9.3Protein K10C9.30.024
F07A11.2Protein F07A11.20.024
daf-19Protein DAF-190.023
gap-2Protein GAP-20.023
rpn-6.1Protein RPN-6.10.023
hmr-1Protein HMR-10.023
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sulf1sulfatase 10.212
tnfsf10ltumor necrosis factor (ligand) superfamily, member 10 like0.210
bidaBH3 interacting domain death agonist0.143
bmp7abone morphogenetic protein 7a0.141
wt1bwilms tumor 1b0.119
desmadesmin a0.090
baxabcl2-associated X protein, a0.082
flot2aflotillin 2a0.081
wnt2bbwingless-type MMTV integration site family, member 2Bb0.081
adrb2aadrenergic receptor, beta 2a0.079
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.079
ahnakAHNAK nucleoprotein0.079
tpm4tropomyosin 40.078
sparcsecreted acidic cysteine rich glycoprotein0.077
tfe3btranscription factor binding to IGHM enhancer 3b0.076
cx43connexin 430.068
mcl1bmyeloid cell leukemia sequence 1b0.061
ccna2cyclin A20.061
dzip1DAZ interacting protein 10.060
hellshelicase, lymphoid-specific0.058
scinlbscinderin like b0.057
nf1aneurofibromin 1a0.056
rtcd1RNA terminal phosphate cyclase domain 10.054
si:ch211-212m21.5si:ch211-212m21.50.052
hmgb2bhigh-mobility group box 2b0.050
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.050
dlx5adistal-less homeobox gene 5a0.050
podxlpodocalyxin-like0.049
gata5GATA-binding protein 50.046
fgfr3fibroblast growth factor receptor 30.044
egr2bearly growth response 2b0.041
postnperiostin, osteoblast specific factor0.039
olfml3bolfactomedin-like 3b0.039
ssrp1astructure specific recognition protein 1a0.039
wif1wnt inhibitory factor 10.038
sox7SRY-box containing gene 70.038
unc5bunc-5 homolog B (C. elegans)0.037
s100a10bS100 calcium binding protein A10b0.036
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.036
plxnb2aplexin b2a0.036
cnn2calponin 20.036
bcl2B-cell leukemia/lymphoma 20.036
mcl1amyeloid cell leukemia sequence 1a0.036
zgc:92867zgc:928670.035
elmo1engulfment and cell motility 1 (ced-12 homolog, C. elegans)0.034
hmgb3ahigh-mobility group box 3a0.034
il8interleukin 80.034
spry2sprouty homolog 20.033
ptrfbpolymerase I and transcript release factor b0.033
mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.033
evx1even-skipped homeobox 10.033
ephb4beph receptor B4b0.032
appbamyloid beta (A4) precursor protein b0.032
pitrm1pitrilysin metalloproteinase 10.031
hmgb2ahigh-mobility group box 2a0.031
msnamoesin a0.031
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.031
s100v2S100 calcium binding protein V20.030
wlswntless homolog (Drosophila)0.030
pole2polymerase (DNA directed), epsilon 20.030
msh6mutS homolog 6 (E. coli)0.029
pdlim1PDZ and LIM domain 1 (elfin)0.029
bcl2l1bcl2-like 10.029
vegfaavascular endothelial growth factor Aa0.028
nf1bneurofibromin 1b0.028
adipoqladiponectin, C1Q and collagen domain containing, like0.028
hspb1heat shock protein, alpha-crystallin-related, 10.027
gsnagelsolin a0.027
fesfeline sarcoma oncogene0.027
dnmt1DNA (cytosine-5-)-methyltransferase 10.027
notch1anotch homolog 1a0.027
mycbp2MYC binding protein 20.026
vtg1vitellogenin 10.026
mmp2matrix metalloproteinase 20.026
psme2proteasome activator subunit 20.026
yrkYes-related kinase0.026
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.026
ncapg2non-SMC condensin II complex, subunit G20.026
perpPERP, TP53 apoptosis effector0.026
ikzf1IKAROS family zinc finger 1 (Ikaros)0.025
hsp90a.2heat shock protein 90-alpha 20.025
caspacaspase a0.025
gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 10.024
dnmt5DNA (cytosine-5-)-methyltransferase 50.024
pcnaproliferating cell nuclear antigen0.023
loxl2blysyl oxidase-like 2b0.023
cep70centrosomal protein 700.023
foxn4forkhead box N40.023
rhoabras homolog gene family, member Ab0.023
ihhaIndian hedgehog homolog a0.023
plxnd1plexin D10.023
LOC567131calcitonin gene-related peptide type 1 receptor-like0.022
wnt11rwingless-type MMTV integration site family, member 11, related0.022
icnictacalcin0.022
dnmt4DNA (cytosine-5-)-methyltransferase 40.022
disp1dispatched homolog 1 (Drosophila)0.021
msh2mutS homolog 2 (E. coli)0.021
kdrlkinase insert domain receptor like0.021
whsc1Wolf-Hirschhorn syndrome candidate 10.021
mycamyelocytomatosis oncogene a0.021
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.994
mbcmyoblast city0.620
pucpuckered0.609
pydpolychaetoid0.604
flwflapwing0.443
Ras85DRas oncogene at 85D0.417
XNPCG4548 gene product from transcript CG4548-RA0.412
mysmyospheroid0.411
Pk61CProtein kinase 61C0.384
PakPAK-kinase0.345
Rac1CG2248 gene product from transcript CG2248-RA0.340
garzgartenzwerg0.333
Ced-12CG5336 gene product from transcript CG5336-RA0.315
kuzkuzbanian0.312
LanALaminin A0.306
AbiAbelson interacting protein0.281
jarjaguar0.269
PliPellino0.259
GitCG16728 gene product from transcript CG16728-RA0.253
SmoxSmad on X0.252
PtenCG5671 gene product from transcript CG5671-RB0.239
ninaCneither inactivation nor afterpotential C0.229
dmdiminutive0.221
drprdraper0.215
stgstring0.203
plexBplexin B0.196
ththread0.185
RnrLRibonucleoside diphosphate reductase large subunit0.173
jumujumeau0.173
nwknervous wreck0.172
cnocanoe0.169
rokRho-kinase0.167
Top3alphaTopoisomerase 3alpha0.165
PknProtein kinase related to protein kinase N0.161
rutrutabaga0.157
CycACyclin A0.156
kibrakibra ortholog0.156
synjsynaptojanin0.155
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.153
DabDisabled0.151
r2d2CG7138 gene product from transcript CG7138-RB0.147
AGO2Argonaute 20.141
pod1CG4532 gene product from transcript CG4532-RF0.140
rolsrolling pebbles0.139
NNotch0.137
rheaCG6831 gene product from transcript CG6831-RA0.134
staistathmin0.130
RhebCG1081 gene product from transcript CG1081-RA0.128
bnlbranchless0.128
Vha100-1CG1709 gene product from transcript CG1709-RF0.128
locolocomotion defects0.128
trioCG18214 gene product from transcript CG18214-RA0.127
mbtmushroom bodies tiny0.126
Pros54Proteasome 54kD subunit0.124
pxplexus0.124
dncdunce0.123
cindrCIN85 and CD2AP orthologue0.123
Mkp3Mitogen-activated protein kinase phosphatase 30.123
Fak56DFocal Adhesion Kinase0.120
cuffcutoff0.120
p120ctnAdherens junction protein p1200.118
CblCG7037 gene product from transcript CG7037-RB0.115
SbfSET domain binding factor0.115
EphrinCG1862 gene product from transcript CG1862-RA0.114
Tre1trapped in endoderm-10.113
lealeak0.111
HemHEM-protein0.111
nbsCG6754 gene product from transcript CG6754-RC0.111
Galpha49BG protein alpha49B0.110
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.110
htlheartless0.110
Dcr-2Dicer-20.109
DreddDeath related ced-3/Nedd2-like protein0.108
edechinoid0.107
mei-41meiotic 410.107
MtlMig-2-like0.106
scbscab0.102
Sin3ACG8815 gene product from transcript CG8815-RC0.101
CG6719CG6719 gene product from transcript CG6719-RA0.101
Rm62CG10279 gene product from transcript CG10279-RD0.100
stumpsCG31317 gene product from transcript CG31317-RC0.100
rstroughest0.099
trptransient receptor potential0.098
rgrugose0.095
CG6509CG6509 gene product from transcript CG6509-RB0.092
RASSF8CG5053 gene product from transcript CG5053-RA0.091
Rpt1CG1341 gene product from transcript CG1341-RA0.090
dikdiskette0.088
CG11347CG11347 gene product from transcript CG11347-RE0.086
Klp61FKinesin-like protein at 61F0.086
NaCP60ENa channel protein 60E0.086
ranCG1404 gene product from transcript CG1404-RB0.085
Prp31CG6876 gene product from transcript CG6876-RA0.085
rkrickets0.083
Cip4CG15015 gene product from transcript CG15015-RA0.083
atlatlastin0.081
carcarnation0.080
Myd88CG2078 gene product from transcript CG2078-RA0.079
Sema-2aCG4700 gene product from transcript CG4700-RC0.078
rlrolled0.077
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Leprleptin receptor1.000
Trp53transformation related protein 530.998
Bcl2B-cell leukemia/lymphoma 20.964
Ctnnb1catenin (cadherin associated protein), beta 10.929
Nr3c1nuclear receptor subfamily 3, group C, member 10.926
Cd44CD44 antigen0.886
Itsn1intersectin 1 (SH3 domain protein 1A)0.868
Tnftumor necrosis factor0.839
Casp4caspase 4, apoptosis-related cysteine peptidase0.822
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.782
Ptprcprotein tyrosine phosphatase, receptor type, C0.771
CblCasitas B-lineage lymphoma0.753
Nos3nitric oxide synthase 3, endothelial cell0.745
Vdrvitamin D receptor0.736
Ccr1chemokine (C-C motif) receptor 10.735
Il2rginterleukin 2 receptor, gamma chain0.735
BaxBCL2-associated X protein0.734
Ptpn6protein tyrosine phosphatase, non-receptor type 60.709
Il1r1interleukin 1 receptor, type I0.699
Hdac7histone deacetylase 70.697
Map3k14mitogen-activated protein kinase kinase kinase 140.666
Egfrepidermal growth factor receptor0.659
Tgfbr2transforming growth factor, beta receptor II0.651
Nf1neurofibromatosis 10.643
PycardPYD and CARD domain containing0.632
Pnpla2patatin-like phospholipase domain containing 20.626
Adam17a disintegrin and metallopeptidase domain 170.621
Klklotho0.618
Ldlrlow density lipoprotein receptor0.609
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.595
Ptenphosphatase and tensin homolog0.587
Vav1vav 1 oncogene0.579
Ighimmunoglobulin heavy chain complex0.558
Mapk14mitogen-activated protein kinase 140.542
Kitkit oncogene0.528
Invsinversin0.526
Rararetinoic acid receptor, alpha0.520
Apcadenomatosis polyposis coli0.515
Pip4k2aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha0.510
Agtr1aangiotensin II receptor, type 1a0.509
Ilkintegrin linked kinase0.507
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.503
Socs1suppressor of cytokine signaling 10.488
Fbn1fibrillin 10.481
Cd28CD28 antigen0.471
Rac1RAS-related C3 botulinum substrate 10.470
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.469
Hdac4histone deacetylase 40.462
Vegfavascular endothelial growth factor A0.461
Mef2amyocyte enhancer factor 2A0.454
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.454
Hmha1histocompatibility (minor) HA-10.451
Ltblymphotoxin B0.444
Efnb2ephrin B20.442
BrafBraf transforming gene0.441
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.440
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.439
Il10rainterleukin 10 receptor, alpha0.432
Arrb2arrestin, beta 20.430
Tgfbr1transforming growth factor, beta receptor I0.427
Drd2dopamine receptor D20.409
Wt1Wilms tumor 1 homolog0.407
Lrp1low density lipoprotein receptor-related protein 10.401
Numbnumb gene homolog (Drosophila)0.399
Elnelastin0.397
Loxlysyl oxidase0.393
Ncoa3nuclear receptor coactivator 30.391
Casp1caspase 10.390
Dnm1dynamin 10.387
Tsc1tuberous sclerosis 10.387
Trp73transformation related protein 730.385
Lama5laminin, alpha 50.370
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.365
WrnWerner syndrome homolog (human)0.363
Psme2proteasome (prosome, macropain) 28 subunit, beta0.363
Jak2Janus kinase 20.361
Itgb1integrin beta 1 (fibronectin receptor beta)0.357
Mlf2myeloid leukemia factor 20.348
Plxna1plexin A10.346
XiapX-linked inhibitor of apoptosis0.341
Lystlysosomal trafficking regulator0.339
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.335
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.327
Rasgrp2RAS, guanyl releasing protein 20.324
Adrb1adrenergic receptor, beta 10.320
Scn5asodium channel, voltage-gated, type V, alpha0.317
Selpselectin, platelet0.316
Hspd1heat shock protein 1 (chaperonin)0.315
Atp7aATPase, Cu++ transporting, alpha polypeptide0.310
Stat5asignal transducer and activator of transcription 5A0.310
Cav1caveolin 1, caveolae protein0.310
Birc3baculoviral IAP repeat-containing 30.308
Adrb3adrenergic receptor, beta 30.308
Ikzf1IKAROS family zinc finger 10.300
Irf1interferon regulatory factor 10.300
Gbp5guanylate binding protein 50.294
FasFas (TNF receptor superfamily member 6)0.292
Cyldcylindromatosis (turban tumor syndrome)0.289
Timm23translocase of inner mitochondrial membrane 23 homolog (yeast)0.286
Retret proto-oncogene0.284
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Jak1Janus kinase 10.450
Albalbumin0.299
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.252
Tmem176btransmembrane protein 176B0.243
S100a8S100 calcium binding protein A80.236
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.221
S100a9S100 calcium binding protein A90.219
Pja2praja 2, RING-H2 motif containing0.212
Nckap1NCK-associated protein 10.210
Homer1homer homolog 1 (Drosophila)0.205
Tgfb1transforming growth factor, beta 10.203
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.191
Copb1coatomer protein complex, subunit beta 10.176
Hk1hexokinase 10.174
Prkcgprotein kinase C, gamma0.168
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.162
Gja1gap junction protein, alpha 10.158
Dnm1ldynamin 1-like0.157
Ccr5chemokine (C-C motif) receptor 50.138
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.137
Clic4chloride intracellular channel 40.137
Adora2aadenosine A2a receptor0.136
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.132
Shank2SH3 and multiple ankyrin repeat domains 20.132
Jak2Janus kinase 20.129
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.128
Epas1endothelial PAS domain protein 10.127
Pdclphosducin-like0.126
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.125
Tgfbr2transforming growth factor, beta receptor II0.120
Gng7guanine nucleotide binding protein (G protein), gamma 70.120
Taglntransgelin0.118
H3f3bH3 histone, family 3B0.114
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.112
Uqcrc1ubiquinol-cytochrome c reductase core protein I0.111
Tmed2transmembrane emp24 domain trafficking protein 20.109
Copb2coatomer protein complex, subunit beta 2 (beta prime)0.106
Camk4calcium/calmodulin-dependent protein kinase IV0.106
Rab3il1RAB3A interacting protein (rabin3)-like 10.105
Cfpcomplement factor properdin0.105
Cd4Cd4 molecule0.102
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.101
Rnase4ribonuclease, RNase A family 40.100
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.100
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.100
Gzmkgranzyme K0.098
Ptpn18protein tyrosine phosphatase, non-receptor type 180.094
RGD1564327similar to integrin alpha 80.093
Cd247Cd247 molecule0.093
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.092
TekTEK tyrosine kinase, endothelial0.092
Inpp5dinositol polyphosphate-5-phosphatase D0.091
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.088
Nkg7natural killer cell group 7 sequence0.087
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.087
Rup2urinary protein 20.087
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.084
Anxa2annexin A20.084
Map3k8mitogen-activated protein kinase kinase kinase 80.083
Hckhemopoietic cell kinase0.082
Dhrs9dehydrogenase/reductase (SDR family) member 90.082
Robo1roundabout homolog 1 (Drosophila)0.081
Mapre1microtubule-associated protein, RP/EB family, member 10.080
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.079
Hrh2histamine receptor H 20.079
Plrg1pleiotropic regulator 1, PRL1 homolog (Arabidopsis)0.079
Adaradenosine deaminase, RNA-specific0.078
Rasgrp1RAS guanyl releasing protein 1 (calcium and DAG-regulated)0.078
Cald1caldesmon 10.077
Casp3caspase 30.076
Pde1bphosphodiesterase 1B, calmodulin-dependent0.076
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.075
Adcy5adenylate cyclase 50.075
Vimvimentin0.075
Vom1r93vomeronasal 1 receptor 930.074
Hbe2hemoglobin, epsilon 20.074
Gna15guanine nucleotide binding protein, alpha 150.074
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.074
Sirpasignal-regulatory protein alpha0.073
Fgfr2fibroblast growth factor receptor 20.072
Impdh2IMP (inosine monophosphate) dehydrogenase 20.071
Acvr1activin A receptor, type I0.071
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.071
Spp2secreted phosphoprotein 20.071
Adrb2adrenergic, beta-2-, receptor, surface0.070
Slc22a7solute carrier family 22 (organic anion transporter), member 70.070
Fshbfollicle stimulating hormone, beta polypeptide0.069
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.069
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.068
KitlgKIT ligand0.068
Zfp260zinc finger protein 2600.068
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.068
Kcnab1potassium voltage-gated channel, shaker-related subfamily, beta member 10.067
Pklrpyruvate kinase, liver and RBC0.067
Prkcbprotein kinase C, beta0.067
Ppp2r2aprotein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform0.067
Fgfr1Fibroblast growth factor receptor 10.066
Myo1bmyosin Ib0.066
Apohapolipoprotein H (beta-2-glycoprotein I)0.066
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.066
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
MKK1Mkk1p0.329
GYL1Gyl1p0.293
DNM1Dnm1p0.251
STE11Ste11p0.220
SDS22Sds22p0.183
GCD6Gcd6p0.169
SUI3Sui3p0.169
STE20Ste20p0.149
RNY1Rny1p0.147
SHY1Shy1p0.142
MSH3Msh3p0.137
ROM2Rom2p0.137
RGA2Rga2p0.132
STI1Sti1p0.132
RHO1Rho1p0.130
CRN1Crn1p0.129
MSH2Msh2p0.128
BCK1Bck1p0.116
RAD52Rad52p0.110
PSP2Psp2p0.110
SEC27Sec27p0.102
HIS6His6p0.102
STE5Ste5p0.097
YME1Yme1p0.095
SCJ1Scj1p0.092
TSR1Tsr1p0.089
TSC11Tsc11p0.089
SLT2Slt2p0.086
SPA2Spa2p0.078
RAS2Ras2p0.074
IRA1Ira1p0.070
GCD11Gcd11p0.069
PTP2Ptp2p0.069
IRC5Irc5p0.068
VPS60Vps60p0.067
CCP1Ccp1p0.064
PKH2Pkh2p0.064
BST1Bst1p0.064
CHC1Chc1p0.062
BIK1Bik1p0.062
HSV2Hsv2p0.061
OCH1Och1p0.059
SEC13Sec13p0.059
FYV8Fyv8p0.059
BEM3Bem3p0.059
AHP1Ahp1p0.059
CDC24Cdc24p0.059
MSP1Msp1p0.058
URA6Ura6p0.057
MBF1Mbf1p0.056
BFR1Bfr1p0.056
PKC1Pkc1p0.054
PAN1Pan1p0.054
AKL1Akl1p0.052
RAD14Rad14p0.052
CLN3Cln3p0.052
MDS3Mds3p0.052
RPG1Rpg1p0.050
YGL036Whypothetical protein0.050
CAK1Cak1p0.050
ENT1Ent1p0.049
YTA6Yta6p0.049
UBP5Ubp5p0.048
CHS1Chs1p0.048
YIP4Yip4p0.048
YPT53Ypt53p0.047
EXO1Exo1p0.047
REB1Reb1p0.047
CDC48Cdc48p0.046
UPS3Ups3p0.046
MON1Mon1p0.046
MPH1Mph1p0.046
NPL4Npl4p0.045
GGA1Gga1p0.045
KEL1Kel1p0.044
PAC11Pac11p0.044
CDC12Cdc12p0.044
POL3Pol3p0.042
ATG21Atg21p0.042
KIP2Kip2p0.042
SAC7Sac7p0.041
NEO1Neo1p0.041
MAS1Mas1p0.041
CDC50Cdc50p0.041
MSG5Msg5p0.040
VPS41Vps41p0.040
STE2Ste2p0.040
VPS9Vps9p0.040
YNR065Chypothetical protein0.039
SLH1Slh1p0.039
TIF5Tif5p0.038
SSL2Ssl2p0.038
YLR257Whypothetical protein0.038
PKH1Pkh1p0.038
ABP1Abp1p0.037
SIS1Sis1p0.036
QCR6Qcr6p0.036
PCL9Pcl9p0.036
SOK1Sok1p0.036
TUS1Tus1p0.036