The network for 'dolichol biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dolichol biosynthetic process

The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.

NameDescriptionProbabilityFunc Analog Organism
SMURF2SMAD specific E3 ubiquitin protein ligase 21.000
RNF11ring finger protein 110.994
NEDD4neural precursor cell expressed, developmentally down-regulated 40.954
WWP2WW domain containing E3 ubiquitin protein ligase 20.939
ZFYVE9zinc finger, FYVE domain containing 90.858
WWP1WW domain containing E3 ubiquitin protein ligase 10.586
SMAD1SMAD family member 10.428
ANKRD13Aankyrin repeat domain 13A0.419
SMAD4SMAD family member 40.408
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.292
FBXL15F-box and leucine-rich repeat protein 150.212
TAX1BP1Tax1 (human T-cell leukemia virus type I) binding protein 10.199
SMURF1SMAD specific E3 ubiquitin protein ligase 10.195
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.171
STAM2signal transducing adaptor molecule (SH3 domain and ITAM motif) 20.150
CXXC5CXXC finger protein 50.142
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.112
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.094
SNX9sorting nexin 90.086
POU5F1POU class 5 homeobox 10.081
NEDD9neural precursor cell expressed, developmentally down-regulated 90.065
SPG20spastic paraplegia 20 (Troyer syndrome)0.058
UBQLN2ubiquilin 20.053
SGK3serum/glucocorticoid regulated kinase family, member 30.045
RNF168ring finger protein 1680.043
TNFAIP3tumor necrosis factor, alpha-induced protein 30.039
SMAD7SMAD family member 70.035
RHOAras homolog gene family, member A0.028
GGA1golgi-associated, gamma adaptin ear containing, ARF binding protein 10.027
SNX18sorting nexin 180.025
CCDC127coiled-coil domain containing 1270.025
STAMBPSTAM binding protein0.022
DTX1deltex homolog 1 (Drosophila)0.022
TRAF4TNF receptor-associated factor 40.018
SMAD6SMAD family member 60.017
RAPGEF2Rap guanine nucleotide exchange factor (GEF) 20.017
OPTNoptineurin0.015
ING2inhibitor of growth family, member 20.013
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.013
ZFAND5zinc finger, AN1-type domain 50.012
MYO6myosin VI0.012
EPS15epidermal growth factor receptor pathway substrate 150.010
ERCC6excision repair cross-complementing rodent repair deficiency, complementation group 60.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
UBI4Ubi4p0.013