The network for 'retina vasculature development in camera type eye' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

retina vasculature development in camera type eye

The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)1.000
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.988
COL4A2collagen, type IV, alpha 20.983
COL4A1collagen, type IV, alpha 10.972
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.931
COL4A3collagen, type IV, alpha 3 (Goodpasture antigen)0.877
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.834
PDGFAplatelet-derived growth factor alpha polypeptide0.816
COL4A4collagen, type IV, alpha 40.803
VEGFAvascular endothelial growth factor A0.628
WNT3Awingless-type MMTV integration site family, member 3A0.502
PRKG1protein kinase, cGMP-dependent, type I0.495
BBS10Bardet-Biedl syndrome 100.466
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.438
EGLN1egl nine homolog 1 (C. elegans)0.435
NID1nidogen 10.396
PDGFCplatelet derived growth factor C0.380
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.341
EGLN3egl nine homolog 3 (C. elegans)0.326
COL4A5collagen, type IV, alpha 50.302
ACVR1activin A receptor, type I0.299
COL4A6collagen, type IV, alpha 60.294
WNT5Awingless-type MMTV integration site family, member 5A0.211
LRRK2leucine-rich repeat kinase 20.208
LAMC1laminin, gamma 1 (formerly LAMB2)0.198
EPAS1endothelial PAS domain protein 10.173
VHLvon Hippel-Lindau tumor suppressor0.155
KAT2BK(lysine) acetyltransferase 2B0.148
MAPK8mitogen-activated protein kinase 80.144
COL16A1collagen, type XVI, alpha 10.134
TGFB3transforming growth factor, beta 30.130
BMPR1Abone morphogenetic protein receptor, type IA0.127
COL5A1collagen, type V, alpha 10.125
NRP1neuropilin 10.122
CAPRIN2caprin family member 20.120
SDCBPsyndecan binding protein (syntenin)0.119
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.105
NID2nidogen 2 (osteonidogen)0.095
ARNTaryl hydrocarbon receptor nuclear translocator0.094
NDPNorrie disease (pseudoglioma)0.092
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.091
ENGendoglin0.089
COL1A1collagen, type I, alpha 10.086
LRP6low density lipoprotein receptor-related protein 60.084
HIF1ANhypoxia inducible factor 1, alpha subunit inhibitor0.080
PLATplasminogen activator, tissue0.079
SSX4synovial sarcoma, X breakpoint 40.077
DKK1dickkopf homolog 1 (Xenopus laevis)0.077
COL6A2collagen, type VI, alpha 20.076
ELF5E74-like factor 5 (ets domain transcription factor)0.073
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.070
PXDNperoxidasin homolog (Drosophila)0.069
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.069
GAB1GRB2-associated binding protein 10.067
CALUcalumenin0.065
JAG1jagged 10.062
CAV1caveolin 1, caveolae protein, 22kDa0.061
PLCG1phospholipase C, gamma 10.060
ADAM9ADAM metallopeptidase domain 90.057
SLASrc-like-adaptor0.057
FNDC3Bfibronectin type III domain containing 3B0.056
EHFets homologous factor0.056
FERMT2fermitin family member 20.052
FCN2ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)0.050
CHST3carbohydrate (chondroitin 6) sulfotransferase 30.050
LAMB1laminin, beta 10.048
SFRP1secreted frizzled-related protein 10.044
CHSY1chondroitin sulfate synthase 10.044
COL5A2collagen, type V, alpha 20.042
FGFR1fibroblast growth factor receptor 10.041
TGFBR1transforming growth factor, beta receptor 10.041
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.040
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.040
FZD8frizzled homolog 8 (Drosophila)0.039
PTENphosphatase and tensin homolog0.038
VCANversican0.037
MEF2Amyocyte enhancer factor 2A0.036
PPAP2Bphosphatidic acid phosphatase type 2B0.036
BMP4bone morphogenetic protein 40.036
NRP2neuropilin 20.036
MCAMmelanoma cell adhesion molecule0.036
BMP2bone morphogenetic protein 20.035
CAV2caveolin 20.033
EFNB2ephrin-B20.033
FOXF2forkhead box F20.033
PID1phosphotyrosine interaction domain containing 10.033
ANGPTL2angiopoietin-like 20.031
FAM46Afamily with sequence similarity 46, member A0.031
COL3A1collagen, type III, alpha 10.030
TWSG1twisted gastrulation homolog 1 (Drosophila)0.030
NFE2L2nuclear factor (erythroid-derived 2)-like 20.030
PTPRFprotein tyrosine phosphatase, receptor type, F0.030
SKILSKI-like oncogene0.029
COL5A3collagen, type V, alpha 30.029
NAMPTnicotinamide phosphoribosyltransferase0.029
GPR124G protein-coupled receptor 1240.029
SERPINH1serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)0.029
PLOD2procollagen-lysine, 2-oxoglutarate 5-dioxygenase 20.028
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.028
MBL2mannose-binding lectin (protein C) 2, soluble0.028
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
kdrlkinase insert domain receptor like0.209
runx1runt-related transcription factor 10.158
nrp2aneuropilin 2a0.095
acvr2aactivin receptor IIa0.089
hspa12bheat shock protein 12B0.062
sox9aSRY-box containing gene 9a0.049
bmpr2abone morphogenetic protein receptor, type II a (serine/threonine kinase)0.041
tfectranscription factor EC0.035
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.034
zgc:77752zgc:777520.033
vegfcvascular endothelial growth factor c0.029
efnb2aephrin B2a0.028
cahzcarbonic anhydrase0.026
ilkintegrin linked kinase0.025
sept7bseptin 7b0.023
dusp5dual specificity phosphatase 50.023
nrp1aneuropilin 1a0.022
notch3notch homolog 30.022
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.021
nrp2bneuropilin 2b0.021
midnmidnolin0.021
ccm2cerebral cavernous malformation 20.021
opn1mw4opsin 1 (cone pigments), medium-wave-sensitive, 40.019
opn4lopsin 4, like0.019
si:dkey-261h17.1si:dkey-261h17.10.019
aqp8a.1aquaporin 8a, tandem duplicate 10.019
stab2stabilin 20.019
opn1mw1opsin 1 (cone pigments), medium-wave-sensitive, 10.018
tal1T-cell acute lymphocytic leukemia 10.017
zeb2azinc finger E-box binding homeobox 2a0.017
npntnephronectin0.017
hdac4histone deacetylase 40.017
LOC100002342carboxypeptidase A6-like0.016
pdcaphosducin a0.016
rbfox2RNA binding protein, fox-1 homolog (C. elegans) 20.016
paqr7bprogestin and adipoQ receptor family member VII, b0.016
arhgap29aRho GTPase activating protein 29a0.016
chd7chromodomain helicase DNA binding protein 70.015
zgc:101614zgc:1016140.015
ntn1anetrin 1a0.015
nrp1bneuropilin 1b0.015
si:ch211-173b8.2si:ch211-173b8.20.015
trim71tripartite motif-containing 710.014
nfatc1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 10.014
mical3flavoprotein oxidoreductase MICAL30.014
f2rcoagulation factor II (thrombin) receptor0.014
wu:fd56d05wu:fd56d050.014
dhrs3adehydrogenase/reductase (SDR family) member 3a0.014
mcambmelanoma cell adhesion molecule b0.014
mapk4mitogen-activated protein kinase 40.014
ddx18DEAD (Asp-Glu-Ala-Asp) box polypeptide 180.014
hapln1bhyaluronan and proteoglycan link protein 1b0.014
gnb3bguanine nucleotide binding protein (G protein), beta polypeptide 3b0.014
igf2bp1insulin-like growth factor 2 mRNA binding protein 10.013
si:ch211-184m19.1si:ch211-184m19.10.013
or125-8odorant receptor, family E, subfamily 125, member 80.013
efna2ephrin A20.013
timp2btissue inhibitor of metalloproteinase 2b0.013
hmbsbhydroxymethylbilane synthase, b0.013
zgc:152984zgc:1529840.012
rykreceptor-like tyrosine kinase0.012
ntn2netrin 20.012
gb:bm036580gb:bm0365800.012
nova2neuro-oncological ventral antigen 20.012
pde6hphosphodiesterase 6H, cGMP-specific, cone, gamma0.012
ret1receptor tyrosine kinase0.011
cldn5aclaudin 5a0.011
metmet proto-oncogene (hepatocyte growth factor receptor)0.011
egr1early growth response 10.011
tie2endothelium-specific receptor tyrosine kinase 20.011
ogt.1O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 10.011
yap1Yes-associated protein 10.011
hs3st3b1bheparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b0.011
kdm5balysine (K)-specific demethylase 5Ba0.011
syt5asynaptotagmin Va0.011
cltcaclathrin, heavy polypeptide a (Hc)0.011
slc8a4bsolute carrier family 8 (sodium/calcium exchanger), member 4b0.011
hk1hexokinase 10.011
dvl2dishevelled, dsh homolog 2 (Drosophila)0.011
bocbrother of CDO0.011
slc2a11lsolute carrier family 2 (facilitated glucose transporter), member 11-like0.011
zgc:109977zgc:1099770.011
mmrn2amultimerin 2a0.011
mecomMDS1 and EVI1 complex locus0.010
nrarpanotch-regulated ankyrin repeat protein a0.010
zgc:66433zgc:664330.010
LOC569232UPF0672 protein CXorf36 homolog0.010
clec14aC-type lectin domain family 14, member A0.010
si:dkey-12o15.1si:dkey-12o15.10.010
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.010
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Vegfavascular endothelial growth factor A0.999
Bmp4bone morphogenetic protein 40.995
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.993
Ctnnb1catenin (cadherin associated protein), beta 10.973
Fgfr2fibroblast growth factor receptor 20.972
Kdrkinase insert domain protein receptor0.966
Acvr1activin A receptor, type 10.933
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.929
Foxc1forkhead box C10.921
Tgfb2transforming growth factor, beta 20.875
Nos3nitric oxide synthase 3, endothelial cell0.868
Cdh5cadherin 50.858
Tgfbr2transforming growth factor, beta receptor II0.825
Ednraendothelin receptor type A0.807
Fgf8fibroblast growth factor 80.806
Ptprbprotein tyrosine phosphatase, receptor type, B0.794
Bmpr1abone morphogenetic protein receptor, type 1A0.782
Gli3GLI-Kruppel family member GLI30.738
Wnt5awingless-related MMTV integration site 5A0.718
Tbx3T-box 30.714
Jag1jagged 10.706
Itgb1integrin beta 1 (fibronectin receptor beta)0.669
Apcadenomatosis polyposis coli0.615
Foxc2forkhead box C20.591
Fgfr1fibroblast growth factor receptor 10.580
Rdh10retinol dehydrogenase 10 (all-trans)0.574
Smad6MAD homolog 6 (Drosophila)0.471
Ror2receptor tyrosine kinase-like orphan receptor 20.468
Meox2mesenchyme homeobox 20.447
Gata4GATA binding protein 40.444
Notch2Notch gene homolog 2 (Drosophila)0.433
Tbx2T-box 20.426
Sema3fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.419
Prrx1paired related homeobox 10.395
Fzd4frizzled homolog 4 (Drosophila)0.381
Smad4MAD homolog 4 (Drosophila)0.380
Ednrbendothelin receptor type B0.347
Gpc3glypican 30.344
Col4a2collagen, type IV, alpha 20.338
Gopcgolgi associated PDZ and coiled-coil motif containing0.327
Bmp7bone morphogenetic protein 70.326
Fgfr3fibroblast growth factor receptor 30.301
Bmp2bone morphogenetic protein 20.298
Col4a3collagen, type IV, alpha 30.283
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.275
Msnmoesin0.269
Lrp6low density lipoprotein receptor-related protein 60.268
Grb10growth factor receptor bound protein 100.266
Shesrc homology 2 domain-containing transforming protein E0.265
Smad3MAD homolog 3 (Drosophila)0.261
Nodalnodal0.259
Csf1colony stimulating factor 1 (macrophage)0.255
Tgfbr1transforming growth factor, beta receptor I0.226
Hspg2perlecan (heparan sulfate proteoglycan 2)0.223
Gja1gap junction protein, alpha 10.205
Smosmoothened homolog (Drosophila)0.199
Ptch1patched homolog 10.191
Slc26a7solute carrier family 26, member 70.188
Ptk2PTK2 protein tyrosine kinase 20.186
Zic3zinc finger protein of the cerebellum 30.182
Itga3integrin alpha 30.174
Psen1presenilin 10.164
Ror1receptor tyrosine kinase-like orphan receptor 10.164
Sox7SRY-box containing gene 70.159
Pdgfbplatelet derived growth factor, B polypeptide0.156
Eporerythropoietin receptor0.153
Efnb2ephrin B20.150
Fzd8frizzled homolog 8 (Drosophila)0.148
Mitfmicrophthalmia-associated transcription factor0.147
Engendoglin0.143
Pecam1platelet/endothelial cell adhesion molecule 10.141
Fbln1fibulin 10.140
Smad2MAD homolog 2 (Drosophila)0.137
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.136
Atp7aATPase, Cu++ transporting, alpha polypeptide0.132
Lamb1laminin B10.122
Crb2crumbs homolog 2 (Drosophila)0.122
Yap1yes-associated protein 10.120
Apaf1apoptotic peptidase activating factor 10.118
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.117
Dlg1discs, large homolog 1 (Drosophila)0.117
Fzd1frizzled homolog 1 (Drosophila)0.115
Pcdh12protocadherin 120.115
Tgfbr3transforming growth factor, beta receptor III0.112
Col1a1collagen, type I, alpha 10.109
Lrp2low density lipoprotein receptor-related protein 20.106
Nid1nidogen 10.104
Egfrepidermal growth factor receptor0.102
Acvr2bactivin receptor IIB0.100
Prrx2paired related homeobox 20.098
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.097
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.094
Arnt2aryl hydrocarbon receptor nuclear translocator 20.092
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.090
Ptenphosphatase and tensin homolog0.090
Pgrprogesterone receptor0.089
Vegfcvascular endothelial growth factor C0.088
Wwc2WW, C2 and coiled-coil domain containing 20.088
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.088
Lama1laminin, alpha 10.087
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism