The network for 'retina vasculature morphogenesis in camera type eye' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

retina vasculature morphogenesis in camera type eye

The process in which the vasculature of the retina is generated and organized.

NameDescriptionProbabilityFunc Analog Organism
VEGFAvascular endothelial growth factor A0.994
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.960
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.937
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.932
NID1nidogen 10.897
WNT3Awingless-type MMTV integration site family, member 3A0.858
COL4A6collagen, type IV, alpha 60.808
LRRK2leucine-rich repeat kinase 20.648
COL1A1collagen, type I, alpha 10.640
COL4A5collagen, type IV, alpha 50.624
LAMC1laminin, gamma 1 (formerly LAMB2)0.596
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.563
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.510
NID2nidogen 2 (osteonidogen)0.446
CAV1caveolin 1, caveolae protein, 22kDa0.422
BBS10Bardet-Biedl syndrome 100.420
WNT5Awingless-type MMTV integration site family, member 5A0.389
SKILSKI-like oncogene0.350
PXDNperoxidasin homolog (Drosophila)0.349
COL5A1collagen, type V, alpha 10.341
COL16A1collagen, type XVI, alpha 10.284
CAPRIN2caprin family member 20.251
DKK1dickkopf homolog 1 (Xenopus laevis)0.226
PGFplacental growth factor0.214
LAMB1laminin, beta 10.213
ELF5E74-like factor 5 (ets domain transcription factor)0.201
APPamyloid beta (A4) precursor protein0.199
CDH5cadherin 5, type 2 (vascular endothelium)0.189
NDPNorrie disease (pseudoglioma)0.187
CALD1caldesmon 10.176
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.166
PLATplasminogen activator, tissue0.162
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.156
FNDC3Bfibronectin type III domain containing 3B0.149
FERMT2fermitin family member 20.142
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.142
MCAMmelanoma cell adhesion molecule0.131
MYL9myosin, light chain 9, regulatory0.130
LRP6low density lipoprotein receptor-related protein 60.126
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.116
THBS1thrombospondin 10.115
CHST3carbohydrate (chondroitin 6) sulfotransferase 30.109
COL6A2collagen, type VI, alpha 20.100
FCN2ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)0.099
SPARCsecreted protein, acidic, cysteine-rich (osteonectin)0.097
IGFBP7insulin-like growth factor binding protein 70.093
FAM46Afamily with sequence similarity 46, member A0.087
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.086
JAG1jagged 10.078
FZD8frizzled homolog 8 (Drosophila)0.078
SERPINH1serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)0.069
HSPG2heparan sulfate proteoglycan 20.069
TRAM1translocation associated membrane protein 10.067
FOXF2forkhead box F20.066
ADAM9ADAM metallopeptidase domain 90.065
HTRA1HtrA serine peptidase 10.064
PID1phosphotyrosine interaction domain containing 10.063
SFRP1secreted frizzled-related protein 10.058
SHC1SHC (Src homology 2 domain containing) transforming protein 10.056
MPP1membrane protein, palmitoylated 1, 55kDa0.055
EHFets homologous factor0.055
VCANversican0.054
FZD1frizzled homolog 1 (Drosophila)0.053
FN1fibronectin 10.053
GPR124G protein-coupled receptor 1240.052
MBL2mannose-binding lectin (protein C) 2, soluble0.051
TWSG1twisted gastrulation homolog 1 (Drosophila)0.051
EDNRAendothelin receptor type A0.051
TIMP3TIMP metallopeptidase inhibitor 30.050
COL18A1collagen, type XVIII, alpha 10.047
RGS2regulator of G-protein signaling 2, 24kDa0.047
CAV2caveolin 20.046
EFNB2ephrin-B20.045
ANXA5annexin A50.044
TGFB2transforming growth factor, beta 20.044
SEPT10septin 100.044
BICD1bicaudal D homolog 1 (Drosophila)0.043
GRB10growth factor receptor-bound protein 100.043
NRP2neuropilin 20.042
LMO4LIM domain only 40.042
NOTCH3notch 30.041
NRP1neuropilin 10.038
APBB2amyloid beta (A4) precursor protein-binding, family B, member 20.038
COL4A2collagen, type IV, alpha 20.038
TGFBR1transforming growth factor, beta receptor 10.037
FBN1fibrillin 10.037
HEG1HEG homolog 1 (zebrafish)0.037
TNCtenascin C0.036
PLS3plastin 30.036
TGFB3transforming growth factor, beta 30.035
SOX17SRY (sex determining region Y)-box 170.035
TCF7L1transcription factor 7-like 1 (T-cell specific, HMG-box)0.034
WWTR1WW domain containing transcription regulator 10.032
NMT2N-myristoyltransferase 20.032
HEY1hairy/enhancer-of-split related with YRPW motif 10.032
SEMA5Bsema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B0.032
COL1A2collagen, type I, alpha 20.031
HDAC6histone deacetylase 60.031
PTPRFprotein tyrosine phosphatase, receptor type, F0.031
PALM2-AKAP2PALM2-AKAP2 readthrough0.031
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
runx1runt-related transcription factor 10.044
nrp2aneuropilin 2a0.017
tfectranscription factor EC0.017
efnb2aephrin B2a0.015
nrp2bneuropilin 2b0.011
cdh5cadherin 50.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Vegfavascular endothelial growth factor A0.883
Itga3integrin alpha 30.798
Wnt5awingless-related MMTV integration site 5A0.727
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.725
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.706
Col4a2collagen, type IV, alpha 20.667
Ctnnb1catenin (cadherin associated protein), beta 10.633
Bmp4bone morphogenetic protein 40.611
Fgfr1fibroblast growth factor receptor 10.520
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.446
Fgfr2fibroblast growth factor receptor 20.426
Notch2Notch gene homolog 2 (Drosophila)0.415
Jag1jagged 10.415
Lamb1laminin B10.389
Gopcgolgi associated PDZ and coiled-coil motif containing0.337
Gpc3glypican 30.322
Plxnd1plexin D10.284
Sema3fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.266
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.259
Kdrkinase insert domain protein receptor0.250
Gata6GATA binding protein 60.205
Msnmoesin0.183
Dlg1discs, large homolog 1 (Drosophila)0.180
Yap1yes-associated protein 10.178
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.172
Rac1RAS-related C3 botulinum substrate 10.172
Hspg2perlecan (heparan sulfate proteoglycan 2)0.167
Dag1dystroglycan 10.163
Col4a3collagen, type IV, alpha 30.160
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.158
Pecam1platelet/endothelial cell adhesion molecule 10.157
Ptk7PTK7 protein tyrosine kinase 70.140
Nid1nidogen 10.133
Ptk2PTK2 protein tyrosine kinase 20.128
Lamc1laminin, gamma 10.127
Tbx2T-box 20.123
Fzd1frizzled homolog 1 (Drosophila)0.122
Smad6MAD homolog 6 (Drosophila)0.120
Fbln1fibulin 10.110
Psen1presenilin 10.110
Tbx3T-box 30.107
Wwtr1WW domain containing transcription regulator 10.105
Itgb1integrin beta 1 (fibronectin receptor beta)0.100
Slc12a6solute carrier family 12, member 60.087
Bcar1breast cancer anti-estrogen resistance 10.077
Lama1laminin, alpha 10.076
Slc26a7solute carrier family 26, member 70.073
Gas1growth arrest specific 10.072
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.071
Lama5laminin, alpha 50.071
Wnt7bwingless-related MMTV integration site 7B0.068
Lrp5low density lipoprotein receptor-related protein 50.067
Ramp2receptor (calcitonin) activity modifying protein 20.065
Bmpr1abone morphogenetic protein receptor, type 1A0.064
Lrp10low-density lipoprotein receptor-related protein 100.062
Vaspvasodilator-stimulated phosphoprotein0.062
Ptprbprotein tyrosine phosphatase, receptor type, B0.062
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.059
Egfrepidermal growth factor receptor0.058
Flt1FMS-like tyrosine kinase 10.054
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.053
Ror1receptor tyrosine kinase-like orphan receptor 10.053
Gli3GLI-Kruppel family member GLI30.052
Wdr1WD repeat domain 10.052
Fzd7frizzled homolog 7 (Drosophila)0.050
Npr3natriuretic peptide receptor 30.050
Pdgfbplatelet derived growth factor, B polypeptide0.050
Tpm4tropomyosin 40.049
Rdh10retinol dehydrogenase 10 (all-trans)0.049
Rhoaras homolog gene family, member A0.048
Tspan12tetraspanin 120.047
Tenc1tensin like C1 domain-containing phosphatase0.047
Foxc1forkhead box C10.046
Pcdh12protocadherin 120.046
Ephb2Eph receptor B20.046
Sox2SRY-box containing gene 20.045
Ror2receptor tyrosine kinase-like orphan receptor 20.043
Cav1caveolin 1, caveolae protein0.043
Pvrl2poliovirus receptor-related 20.042
Col18a1collagen, type XVIII, alpha 10.042
Tnks1bp1tankyrase 1 binding protein 10.042
Tinagl1tubulointerstitial nephritis antigen-like 10.042
Sfrp1secreted frizzled-related protein 10.042
Lamb2laminin, beta 20.041
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.041
Grb7growth factor receptor bound protein 70.041
Pick1protein interacting with C kinase 10.041
Taglntransgelin0.040
Spna1spectrin alpha 10.040
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.039
Largelike-glycosyltransferase0.039
Bmp1bone morphogenetic protein 10.038
Cdh5cadherin 50.036
Ltbrlymphotoxin B receptor0.036
Hoxb6homeobox B60.036
Sardhsarcosine dehydrogenase0.036
Col4a1collagen, type IV, alpha 10.034
Phldb2pleckstrin homology-like domain, family B, member 20.033
Rnd3Rho family GTPase 30.033
Notch3Notch gene homolog 3 (Drosophila)0.033
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism