The network for 'regulation of response to osmotic stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of response to osmotic stress

Any process that modulates the rate or extent of the response to osmotic stress.

NameDescriptionProbabilityFunc Analog Organism
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.512
MAPK1mitogen-activated protein kinase 10.436
FBXO33F-box protein 330.275
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.252
PTPRRprotein tyrosine phosphatase, receptor type, R0.182
YBX1Y box binding protein 10.143
DUSP3dual specificity phosphatase 30.119
PTPRJprotein tyrosine phosphatase, receptor type, J0.117
PTPN7protein tyrosine phosphatase, non-receptor type 70.117
GRB10growth factor receptor-bound protein 100.089
EPORerythropoietin receptor0.087
DUSP7dual specificity phosphatase 70.072
JAK2Janus kinase 20.071
DUSP6dual specificity phosphatase 60.070
MAPK3mitogen-activated protein kinase 30.066
PABPC4poly(A) binding protein, cytoplasmic 4 (inducible form)0.056
CUL1cullin 10.049
DUSP1dual specificity phosphatase 10.042
STAT5Asignal transducer and activator of transcription 5A0.039
CSDAcold shock domain protein A0.039
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.038
PEBP4phosphatidylethanolamine-binding protein 40.036
PEA15phosphoprotein enriched in astrocytes 150.032
PKM2pyruvate kinase, muscle0.028
PLCG1phospholipase C, gamma 10.027
PDK1pyruvate dehydrogenase kinase, isozyme 10.026
BCAR1breast cancer anti-estrogen resistance 10.025
METmet proto-oncogene (hepatocyte growth factor receptor)0.023
RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 30.017
MAPK14mitogen-activated protein kinase 140.016
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.016
CBLCCas-Br-M (murine) ecotropic retroviral transforming sequence c0.016
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.016
STAT5Bsignal transducer and activator of transcription 5B0.016
UBXN6UBX domain protein 60.015
BAG1BCL2-associated athanogene0.014
IRS1insulin receptor substrate 10.014
NEDD9neural precursor cell expressed, developmentally down-regulated 90.014
DTX1deltex homolog 1 (Drosophila)0.013
HABP4hyaluronan binding protein 40.012
SOCS2suppressor of cytokine signaling 20.012
SRSF9serine/arginine-rich splicing factor 90.012
CAPN1calpain 1, (mu/I) large subunit0.011
HMGA1high mobility group AT-hook 10.011
SMU1smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)0.011
MTPNmyotrophin0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ren1renin 1 structural0.715
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.362
Fbn1fibrillin 10.244
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.157
Agtr1aangiotensin II receptor, type 1a0.092
Agtrapangiotensin II, type I receptor-associated protein0.089
Adora3adenosine A3 receptor0.079
Efemp2epidermal growth factor-containing fibulin-like extracellular matrix protein 20.077
NsfN-ethylmaleimide sensitive fusion protein0.077
Leprleptin receptor0.076
Cldn16claudin 160.072
Slc4a1solute carrier family 4 (anion exchanger), member 10.056
Mbmyoglobin0.056
Tgfbr2transforming growth factor, beta receptor II0.053
Aqp2aquaporin 20.052
Pcdh12protocadherin 120.047
Alas2aminolevulinic acid synthase 2, erythroid0.042
RhagRhesus blood group-associated A glycoprotein0.040
Loxlysyl oxidase0.035
Nos3nitric oxide synthase 3, endothelial cell0.034
Ldlrlow density lipoprotein receptor0.034
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.030
Spna1spectrin alpha 10.029
Aprtadenine phosphoribosyl transferase0.029
Wt1Wilms tumor 1 homolog0.028
Nos2nitric oxide synthase 2, inducible0.027
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.025
Hdgfhepatoma-derived growth factor0.023
Nos1nitric oxide synthase 1, neuronal0.022
Rgs12regulator of G-protein signaling 120.022
Slc12a1solute carrier family 12, member 10.021
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.020
Trim10tripartite motif-containing 100.017
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.017
Umoduromodulin0.017
Vdrvitamin D receptor0.016
Cyp11b2cytochrome P450, family 11, subfamily b, polypeptide 20.016
Ahspalpha hemoglobin stabilizing protein0.015
Hras1Harvey rat sarcoma virus oncogene 10.015
Bdkrb2bradykinin receptor, beta 20.015
Gja1gap junction protein, alpha 10.015
Elnelastin0.015
Csnk2bcasein kinase 2, beta polypeptide0.015
Itgb3integrin beta 30.014
Agtr1bangiotensin II receptor, type 1b0.014
Sncasynuclein, alpha0.014
Nfe2nuclear factor, erythroid derived 20.014
Has2hyaluronan synthase 20.014
Ptgs2prostaglandin-endoperoxide synthase 20.013
Uroc1urocanase domain containing 10.013
Glis2GLIS family zinc finger 20.013
Edn1endothelin 10.013
Sox18SRY-box containing gene 180.013
Ubcubiquitin C0.012
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.012
Ermaperythroblast membrane-associated protein0.012
Tal1T-cell acute lymphocytic leukemia 10.012
Dmddystrophin, muscular dystrophy0.011
Tjp1tight junction protein 10.011
Klklotho0.011
Mfsd5major facilitator superfamily domain containing 50.011
Hbb-bh1hemoglobin Z, beta-like embryonic chain0.011
Mpomyeloperoxidase0.011
Slc38a5solute carrier family 38, member 50.011
Rnf126ring finger protein 1260.011
Snai2snail homolog 2 (Drosophila)0.010
Bcl6bB-cell CLL/lymphoma 6, member B0.010
Hbb-b2hemoglobin, beta adult minor chain0.010
Robo2roundabout homolog 2 (Drosophila)0.010
Cdc34cell division cycle 34 homolog (S. cerevisiae)0.010
Duox1dual oxidase 10.010
RhdRh blood group, D antigen0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
SSK2Ssk2p0.315
CRZ1Crz1p0.183
GAT2Gat2p0.089
GLN3Gln3p0.075
MIG2Mig2p0.069
OPY2Opy2p0.060
MSN4Msn4p0.041
RLM1Rlm1p0.039
HXT3Hxt3p0.039
SSK1Ssk1p0.039
UTP20Utp20p0.038
VID24Vid24p0.037
MIG1Mig1p0.036
STE11Ste11p0.035
STE5Ste5p0.032
SGV1Sgv1p0.032
SSK22Ssk22p0.029
MOB1Mob1p0.027
AFT1Aft1p0.027
MSG5Msg5p0.027
MET4Met4p0.026
MIG3Mig3p0.025
TOR2Tor2p0.025
FPK1Fpk1p0.025
RGS2Rgs2p0.025
SMP1Smp1p0.024
YPK2Ypk2p0.024
FAA2Faa2p0.024
PRR2Prr2p0.023
ESF1Esf1p0.023
HAL5Hal5p0.022
HAL1Hal1p0.020
MSN1Msn1p0.019
PBS2Pbs2p0.019
SFL1Sfl1p0.019
YKR075Chypothetical protein0.018
CSR2Csr2p0.018
UBP9Ubp9p0.018
YMR102Chypothetical protein0.018
YAP5Yap5p0.017
TYE7Tye7p0.016
YPR157Whypothetical protein0.016
MOT3Mot3p0.016
LYS5Lys5p0.016
SAK1Sak1p0.016
SLT2Slt2p0.016
ZAP1Zap1p0.016
ICY1Icy1p0.015
MSN5Msn5p0.015
ROX1Rox1p0.015
AVO1Avo1p0.015
VPS64Vps64p0.015
PTC5Ptc5p0.015
VHS1Vhs1p0.014
YNL234Whypothetical protein0.014
IRC23Irc23p0.014
ARE2Are2p0.014
MDM32Mdm32p0.014
RSC9Rsc9p0.014
RGD1Rgd1p0.014
POG1Pog1p0.014
YDR186Chypothetical protein0.013
YGR035Chypothetical protein0.013
NBP2Nbp2p0.013
DOT6Dot6p0.013
MSN2Msn2p0.013
HRQ1Hrq1p0.013
YPL168Whypothetical protein0.013
SKS1Sks1p0.013
STL1Stl1p0.013
ADR1Adr1p0.013
FMP48Fmp48p0.012
DAL81Dal81p0.012
DBF2Dbf2p0.012
YKL187Chypothetical protein0.012
PSR2Psr2p0.012
STP3Stp3p0.011
SOG2Sog2p0.011
FPS1Fps1p0.011
YIR035Chypothetical protein0.011
YLR297Whypothetical protein0.011
RPI1Rpi1p0.011
SNF1Snf1p0.011
YPL066Whypothetical protein0.011
YLR278Chypothetical protein0.011
RFX1Rfx1p0.011
SWI1Swi1p0.011
SRD1Srd1p0.011
HMS1Hms1p0.011
TPO2Tpo2p0.011
SNF3Snf3p0.011
YMR295Chypothetical protein0.011
EBS1Ebs1p0.011
YDR034W-Bhypothetical protein0.011
ECM30Ecm30p0.010
TIP1Tip1p0.010
ATF1Atf1p0.010
SKN7Skn7p0.010
HSF1Hsf1p0.010
STE13Ste13p0.010