The network for 'innate immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

innate immune response

Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

NameDescriptionProbabilityFunc Analog Organism
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma1.000
MYD88myeloid differentiation primary response gene (88)0.999
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.999
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.997
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.990
TRAF6TNF receptor-associated factor 60.990
RIPK2receptor-interacting serine-threonine kinase 20.984
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.981
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.980
IRAK1interleukin-1 receptor-associated kinase 10.978
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.977
UBCubiquitin C0.967
BIRC3baculoviral IAP repeat containing 30.965
SHC1SHC (Src homology 2 domain containing) transforming protein 10.965
SP110SP110 nuclear body protein0.958
IFI44interferon-induced protein 440.956
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.954
IFIH1interferon induced with helicase C domain 10.945
OAS22'-5'-oligoadenylate synthetase 2, 69/71kDa0.944
B2Mbeta-2-microglobulin0.943
NCF1neutrophil cytosolic factor 10.937
BIRC2baculoviral IAP repeat containing 20.935
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.935
MAPK14mitogen-activated protein kinase 140.932
IRF9interferon regulatory factor 90.928
EGFRepidermal growth factor receptor0.917
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.915
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.914
MAP3K5mitogen-activated protein kinase kinase kinase 50.914
HLA-Cmajor histocompatibility complex, class I, C0.900
LATlinker for activation of T cells0.899
MAP3K7mitogen-activated protein kinase kinase kinase 70.896
TNFAIP3tumor necrosis factor, alpha-induced protein 30.890
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.889
HIST1H2BDhistone cluster 1, H2bd0.884
JAK2Janus kinase 20.884
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.872
SMN1survival of motor neuron 1, telomeric0.870
RXRAretinoid X receptor, alpha0.869
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.865
IFIT3interferon-induced protein with tetratricopeptide repeats 30.850
ARRB1arrestin, beta 10.844
CXCL10chemokine (C-X-C motif) ligand 100.837
CHUKconserved helix-loop-helix ubiquitous kinase0.835
OAS12',5'-oligoadenylate synthetase 1, 40/46kDa0.832
PVRL1poliovirus receptor-related 1 (herpesvirus entry mediator C)0.829
HIST1H2BFhistone cluster 1, H2bf0.825
HIST1H2BEhistone cluster 1, H2be0.818
HLA-Bmajor histocompatibility complex, class I, B0.812
HLA-Amajor histocompatibility complex, class I, A0.809
STAT1signal transducer and activator of transcription 1, 91kDa0.802
GBP1guanylate binding protein 1, interferon-inducible0.800
XIAPX-linked inhibitor of apoptosis0.798
CCR1chemokine (C-C motif) receptor 10.793
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.785
IRAK2interleukin-1 receptor-associated kinase 20.774
FYNFYN oncogene related to SRC, FGR, YES0.772
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.766
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.766
FASFas (TNF receptor superfamily, member 6)0.758
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.753
FGAfibrinogen alpha chain0.742
PYCARDPYD and CARD domain containing0.734
C1Scomplement component 1, s subcomponent0.733
APOEapolipoprotein E0.727
HLA-Emajor histocompatibility complex, class I, E0.724
IFI44Linterferon-induced protein 44-like0.721
MX1myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)0.712
IFITM1interferon induced transmembrane protein 1 (9-27)0.708
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.700
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.700
NMIN-myc (and STAT) interactor0.694
GRB7growth factor receptor-bound protein 70.691
ICAM1intercellular adhesion molecule 10.684
SH2D1ASH2 domain containing 1A0.672
KRT15keratin 150.661
S100A8S100 calcium binding protein A80.657
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.656
SQSTM1sequestosome 10.650
MED10mediator complex subunit 100.648
CXCL9chemokine (C-X-C motif) ligand 90.645
MAPK1mitogen-activated protein kinase 10.638
BTKBruton agammaglobulinemia tyrosine kinase0.638
SIGLEC7sialic acid binding Ig-like lectin 70.635
KLRD1killer cell lectin-like receptor subfamily D, member 10.635
CALM1calmodulin 1 (phosphorylase kinase, delta)0.632
CASP8caspase 8, apoptosis-related cysteine peptidase0.631
IFIT2interferon-induced protein with tetratricopeptide repeats 20.624
IFITM3interferon induced transmembrane protein 3 (1-8U)0.622
TLR2toll-like receptor 20.614
TRIM21tripartite motif containing 210.613
TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 20.611
CD163CD163 molecule0.607
HIST1H2BHhistone cluster 1, H2bh0.599
OASL2'-5'-oligoadenylate synthetase-like0.593
GHRgrowth hormone receptor0.580
CCR5chemokine (C-C motif) receptor 50.574
FGL2fibrinogen-like 20.573
MAP2K4mitogen-activated protein kinase kinase 40.568
SYKspleen tyrosine kinase0.564
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
dod-24Protein DOD-240.995
C34H4.2Protein C34H4.20.984
C18E9.9Protein C18E9.90.981
lys-2Protein LYS-20.979
CELE_C17H12.8Protein C17H12.80.975
C34H4.1Protein C34H4.10.955
F08G5.6Protein F08G5.60.927
dod-17Protein DOD-170.920
ugt-44Protein UGT-440.893
lys-1Protein LYS-10.891
hsp-17Protein HSP-170.890
clec-67Protein CLEC-670.890
CELE_F55G11.2Protein F55G11.20.879
clec-265Protein CLEC-2650.877
T01D3.6Protein T01D3.60.867
tag-244Protein TAG-2440.862
C29F3.7Protein C29F3.70.855
tag-120Protein TAG-1200.847
T24C4.4Protein T24C4.40.844
gst-7Protein GST-70.843
CELE_K08D8.6Protein K08D8.60.838
CELE_C32H11.4Protein C32H11.40.828
CELE_K08D8.5Protein K08D8.50.816
hpo-6Protein HPO-60.816
T28D9.3Protein T28D9.30.804
lys-3Protein LYS-30.789
CELE_F55G11.8Protein F55G11.80.788
T20D3.2Protein T20D3.20.773
zip-5Protein ZIP-50.762
gst-6Protein GST-60.758
clec-66Protein CLEC-660.751
his-5Protein HIS-50.737
CELE_Y40D12A.2Protein Y40D12A.20.725
T19D12.4Protein T19D12.40.715
C49C8.5Protein C49C8.50.702
dod-22Protein DOD-220.697
cpr-1Protein CPR-10.696
clc-1Protein CLC-10.695
CELE_F55G11.4Protein F55G11.40.692
cyp-35C1Protein CYP-35C10.691
gst-22Protein GST-220.681
CELE_F53C11.1Protein F53C11.10.672
F09A5.4Protein F09A5.40.669
K06G5.1Protein K06G5.10.667
cpr-3Protein CPR-30.666
CELE_F35E12.5Protein F35E12.50.664
CELE_F53B2.8Protein F53B2.80.663
lec-10Protein LEC-100.657
cdr-4Protein CDR-40.649
ttm-5Protein TTM-50.647
dod-19Protein DOD-190.631
col-157Protein COL-1570.630
asp-6Protein ASP-60.621
his-39Protein HIS-390.615
his-4Protein HIS-40.615
sqt-1Protein SQT-10.613
CELE_F19B2.5Protein F19B2.50.612
ncs-2Protein NCS-20.610
CELE_C29F7.2Protein C29F7.20.606
lys-8Protein LYS-80.602
sek-1Protein SEK-10.592
C18H9.6Protein C18H9.60.591
his-16Protein HIS-160.587
CELE_F35E12.8Protein F35E12.80.582
gst-4Protein GST-40.580
his-52Protein HIS-520.580
clec-41Protein CLEC-410.578
CELE_ZK1320.3Protein ZK1320.30.577
zip-2Protein ZIP-20.567
C16B8.3Protein C16B8.30.567
F53A9.1Protein F53A9.10.566
dpy-4Protein DPY-40.565
clec-83Protein CLEC-830.562
col-17Protein COL-170.541
col-92Protein COL-920.540
K11H12.4Protein K11H12.40.532
Y37D8A.16Protein Y37D8A.160.529
his-3Protein HIS-30.528
F58A6.1Protein F58A6.10.525
CELE_F35E12.6Protein F35E12.60.524
CELE_F49F1.6Protein F49F1.60.522
ugt-1Protein UGT-10.521
acbp-3Protein ACBP-30.518
W01A11.1Protein W01A11.10.503
F46G10.1Protein F46G10.10.501
CELE_K09D9.1Protein K09D9.10.495
CELE_C17H12.6Protein C17H12.60.488
ugt-22Protein UGT-220.486
CELE_F54D5.4Protein F54D5.40.484
CELE_F01D5.1Protein F01D5.10.480
F54E2.1Protein F54E2.10.479
rol-6Protein ROL-60.476
Y77E11A.2Protein Y77E11A.20.472
col-119Protein COL-1190.470
CELE_Y41D4B.17Protein Y41D4B.170.466
C35B1.5Protein C35B1.50.464
col-43Protein COL-430.464
ZK970.7Protein ZK970.70.460
col-140Protein COL-1400.457
C16D9.4Protein C16D9.40.455
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
cdh1cadherin 1, epithelial0.444
notch3notch homolog 30.308
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.242
ptgdsprostaglandin D2 synthase0.225
ef1aelongation factor 1-alpha0.200
pcsk5aproprotein convertase subtilisin/kexin type 5a0.199
nanos3nanos homolog 30.196
irf11interferon regulatory factor 110.185
LOC100151531zinc finger protein Gfi-1b-like0.184
pcsk2proprotein convertase subtilisin/kexin type 20.159
elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.155
apobapolipoprotein B0.150
nod1nucleotide-binding oligomerization domain containing 10.145
pcsk1proprotein convertase subtilisin/kexin type 10.134
mmp9matrix metalloproteinase 90.128
cyt1type I cytokeratin, enveloping layer0.125
coro1acoronin, actin binding protein, 1A0.118
aldobaldolase b, fructose-bisphosphate0.116
cd63Cd63 antigen0.114
foxi3aforkhead box I3a0.113
tlr21toll-like receptor 210.111
tlr3toll-like receptor 30.102
rargaretinoic acid receptor gamma a0.098
tlr9toll-like receptor 90.093
vasavasa homolog0.093
pycardPYD and CARD domain containing0.092
caspacaspase a0.090
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.087
stat5.1signal transducer and activator of transcription 5.10.085
itm2bbintegral membrane protein 2Bb0.084
foxa1forkhead box A10.084
atf3activating transcription factor 30.082
pcsk7proprotein convertase subtilisin/kexin type 70.081
pcsk9proprotein convertase subtilisin/kexin type 90.079
nfe2nuclear factor, erythroid-derived 20.074
cdx1bcaudal type homeobox 1 b0.071
sox7SRY-box containing gene 70.071
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.067
furinbfurin (paired basic amino acid cleaving enzyme) b0.064
upp2uridine phosphorylase 20.064
ptgs1prostaglandin-endoperoxide synthase 10.064
comtacatechol-O-methyltransferase a0.063
adra2badrenergic, alpha-2B-, receptor0.063
kdrlkinase insert domain receptor like0.062
tnfbtumor necrosis factor b (TNF superfamily, member 2)0.062
sult3st1sulfotransferase family 3, cytosolic sulfotransferase 10.061
LOC557072caspase recruitment domain-containing protein 11-like0.060
plagl2pleiomorphic adenoma gene-like 20.058
cyp2y3cytochrome P450, family 2, subfamily Y, polypeptide 30.058
cbr1lcarbonyl reductase 1-like0.057
nos2anitric oxide synthase 2a, inducible0.057
efnb3bephrin B3b0.056
bocbrother of CDO0.056
stat3signal transduction and activation of transcription 30.055
b2mbeta-2-microglobulin0.055
keap1akelch-like ECH-associated protein 1a0.054
mat2amethionine adenosyltransferase II, alpha0.054
eif3hbeukaryotic translation initiation factor 3, subunit H, b0.052
rhogbras homolog gene family, member Gb0.051
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.051
c1qccomplement component 1, q subcomponent, C chain0.049
sgpp1sphingosine-1-phosphate phosphatase 10.049
hdrhematopoietic death receptor0.049
adra2aadrenergic, alpha-2A-, receptor0.048
sh3gl1bSH3-domain GRB2-like 1b0.048
psme1proteasome activator subunit 10.047
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.046
nr2f5nuclear receptor subfamily 2, group F, member 50.046
lppLIM domain containing preferred translocation partner in lipoma0.046
rbpjarecombination signal binding protein for immunoglobulin kappa J region a0.046
fgfr3fibroblast growth factor receptor 30.045
six1bsine oculis homeobox homolog 1b0.045
tie1endothelium-specific receptor tyrosine kinase 10.044
smad1MAD homolog 1 (Drosophila)0.044
sp2sp2 transcription factor0.042
lipclipase, hepatic0.042
shbgsex hormone binding globulin0.042
sfrp5secreted frizzled-related protein 50.042
itln3intelectin 30.041
pknox1.2pbx/knotted 1 homeobox 1.20.041
tnfrsfatumor necrosis factor receptor superfamily, member a0.041
irak4interleukin-1 receptor-associated kinase 40.041
il6stinterleukin 6 signal transducer0.041
LOC100000934hypothetical protein LOC1000009340.040
tlr4bbtoll-like receptor 4b, duplicate b0.040
cldn2claudin 20.040
hpxhemopexin0.039
cldngclaudin g0.039
copb2coatomer protein complex, subunit beta 20.039
tgfb3transforming growth factor, beta 30.039
mitfamicrophthalmia-associated transcription factor a0.039
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.038
ncor1nuclear receptor co-repressor 10.038
mapk3mitogen-activated protein kinase 30.038
tal1T-cell acute lymphocytic leukemia 10.037
hspa5heat shock protein 50.037
si:ch211-212m21.5si:ch211-212m21.50.036
mgaMAX gene associated0.035
yarstyrosyl-tRNA synthetase0.035
wasaWiskott-Aldrich syndrome (eczema-thrombocytopenia) a0.035
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PGRP-LCPeptidoglycan recognition protein LC1.000
RelRelish0.992
AttAAttacin-A0.987
Spn27ASerpin 27A0.973
fonfondue0.968
spzspatzle0.963
Jon99CiiiJonah 99Ciii0.937
p38bCG7393 gene product from transcript CG7393-RA0.915
DptBDiptericin B0.910
PGRP-SAPeptidoglycan recognition protein SA0.904
AGO2Argonaute 20.872
Dcr-2Dicer-20.868
CG18594CG18594 gene product from transcript CG18594-RA0.868
Akt1CG4006 gene product from transcript CG4006-RA0.868
grassGram-positive Specific Serine protease0.867
Sp7Serine protease 70.862
DreddDeath related ced-3/Nedd2-like protein0.848
CG6361CG6361 gene product from transcript CG6361-RA0.846
BG4CG12297 gene product from transcript CG12297-RA0.791
PGRP-SDCG7496 gene product from transcript CG7496-RA0.790
Dhc64CDynein heavy chain 64C0.787
proPO-A1prophenol oxidase A10.784
Lcp3Larval cuticle protein 30.734
IM18Immune induced molecule 180.730
Flo-2flotillin 20.674
Lsp1alphaLarval serum protein 1 alpha0.672
Spn1Serine protease inhibitor 10.671
Mekk1CG7717 gene product from transcript CG7717-RB0.661
IrcImmune-regulated catalase0.661
yip7yippee interacting protein 70.644
imdimmune deficiency0.640
putpunt0.635
GNBP3Gram-negative bacteria binding protein 30.631
alphaTryalphaTrypsin0.626
liclicorne0.626
MtkMetchnikowin0.623
Nrx-IVNeurexin IV0.619
Jon65AiJonah 65Ai0.612
Ras85DRas oncogene at 85D0.605
pzgputzig0.596
GltGlutactin0.596
CG32185CG32185 gene product from transcript CG32185-RA0.594
CG8193CG8193 gene product from transcript CG8193-RA0.586
CG15917CG15917 gene product from transcript CG15917-RA0.584
SPESpatzle-Processing Enzyme0.582
Rac2CG8556 gene product from transcript CG8556-RA0.581
eaterCG6124 gene product from transcript CG6124-RB0.573
Spn28DSerpin 28D0.571
PGRP-SC1aCG14746 gene product from transcript CG14746-RA0.560
DuoxDual oxidase0.548
PliPellino0.545
Lis-1Lissencephaly-10.545
diadiaphanous0.541
TlToll0.533
Mpk2CG5475 gene product from transcript CG5475-RB0.515
CG6295CG6295 gene product from transcript CG6295-RA0.512
stcksteamer duck0.510
l(3)mbnlethal (3) malignant blood neoplasm0.498
Myd88CG2078 gene product from transcript CG2078-RA0.489
CG10472CG10472 gene product from transcript CG10472-RA0.480
piepineapple eye0.452
PGRP-LFPeptidoglycan recognition protein LF0.452
krzkurtz0.443
AttCAttacin-C0.432
betaTrybetaTrypsin0.412
domedomeless0.411
CHORDCG6198 gene product from transcript CG6198-RA0.402
CG5794CG5794 gene product from transcript CG5794-RB0.400
ExnEphexin0.399
DrsDrosomycin0.390
Rac1CG2248 gene product from transcript CG2248-RA0.382
modSPmodular serine protease0.379
Cdc42CG12530 gene product from transcript CG12530-RA0.378
HmlHemolectin0.376
McrMacroglobulin complement-related0.375
Atg1Autophagy-specific gene 10.360
cactcactus0.359
epsilonTryepsilonTrypsin0.355
MadMothers against dpp0.353
LysELysozyme E0.345
Cpr49AeCuticular protein 49Ae0.338
CG17633CG17633 gene product from transcript CG17633-RA0.338
Lcp2Larval cuticle protein 20.336
ird1immune response deficient 10.332
Pvf2PDGF- and VEGF-related factor 20.330
CG16718CG16718 gene product from transcript CG16718-RA0.325
KrnKeren0.324
GNBP1Gram-negative bacteria binding protein 10.322
AdhAlcohol dehydrogenase0.317
maelmaelstrom0.314
Top2Topoisomerase 20.312
PGRP-LBPeptidoglycan recognition protein LB0.311
vavCG7893 gene product from transcript CG7893-RB0.310
ParpPoly-(ADP-ribose) polymerase0.310
pntpointed0.309
LysDLysozyme D0.308
p53CG33336 gene product from transcript CG33336-RB0.305
CG15515CG15515 gene product from transcript CG15515-RA0.296
Nipped-ACG33554 gene product from transcript CG33554-RE0.294
TM9SF4CG7364 gene product from transcript CG7364-RA0.289
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Stat1signal transducer and activator of transcription 10.997
Irf9interferon regulatory factor 90.988
Casp4caspase 4, apoptosis-related cysteine peptidase0.982
Myd88myeloid differentiation primary response gene 880.978
Ccr2chemokine (C-C motif) receptor 20.974
Lyz2lysozyme 20.973
Trim21tripartite motif-containing 210.971
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.970
Irf7interferon regulatory factor 70.967
Ctnnb1catenin (cadherin associated protein), beta 10.962
Klrk1killer cell lectin-like receptor subfamily K, member 10.958
Gbp2guanylate binding protein 20.958
Mapk14mitogen-activated protein kinase 140.956
Tlr4toll-like receptor 40.956
Igtpinterferon gamma induced GTPase0.953
Gbp7guanylate binding protein 70.952
Cd180CD180 antigen0.950
Gbp3guanylate binding protein 30.949
Ccl2chemokine (C-C motif) ligand 20.944
H2-DMb2histocompatibility 2, class II, locus Mb20.934
Tgfbr2transforming growth factor, beta receptor II0.929
Cd40CD40 antigen0.927
H2-Eb1histocompatibility 2, class II antigen E beta0.923
Map3k8mitogen-activated protein kinase kinase kinase 80.917
Irf1interferon regulatory factor 10.910
Irgm2immunity-related GTPase family M member 20.904
Uba7ubiquitin-like modifier activating enzyme 70.897
Iigp1interferon inducible GTPase 10.892
H2-Aahistocompatibility 2, class II antigen A, alpha0.891
Csf1colony stimulating factor 1 (macrophage)0.886
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.881
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.875
Stat3signal transducer and activator of transcription 30.872
Tnfaip3tumor necrosis factor, alpha-induced protein 30.869
Klra9killer cell lectin-like receptor subfamily A, member 90.865
Ciitaclass II transactivator0.862
Ikbkginhibitor of kappaB kinase gamma0.860
H2-K1histocompatibility 2, K1, K region0.856
Cd74CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)0.856
Ifitm3interferon induced transmembrane protein 30.855
Klrd1killer cell lectin-like receptor, subfamily D, member 10.850
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.842
Irgm1immunity-related GTPase family M member 10.841
Icosinducible T-cell co-stimulator0.839
Parp14poly (ADP-ribose) polymerase family, member 140.836
Il6interleukin 60.833
Cxcl10chemokine (C-X-C motif) ligand 100.824
Ear2eosinophil-associated, ribonuclease A family, member 20.824
Tnftumor necrosis factor0.817
Ncoa3nuclear receptor coactivator 30.816
Ccl5chemokine (C-C motif) ligand 50.802
Rac1RAS-related C3 botulinum substrate 10.801
TapbpTAP binding protein0.789
Bcl3B-cell leukemia/lymphoma 30.787
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.784
Nf1neurofibromatosis 10.783
Ifnginterferon gamma0.782
Cd19CD19 antigen0.780
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.770
Socs1suppressor of cytokine signaling 10.765
Casp1caspase 10.763
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.757
AW112010expressed sequence AW1120100.751
Map3k7mitogen-activated protein kinase kinase kinase 70.745
Oasl22'-5' oligoadenylate synthetase-like 20.744
Efnb2ephrin B20.743
Ddx58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.739
Ikbkbinhibitor of kappaB kinase beta0.739
H2-Q7histocompatibility 2, Q region locus 70.736
Xcl1chemokine (C motif) ligand 10.735
Birc3baculoviral IAP repeat-containing 30.732
Usp18ubiquitin specific peptidase 180.721
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.714
Cxcl9chemokine (C-X-C motif) ligand 90.714
Gzmagranzyme A0.711
Slamf1signaling lymphocytic activation molecule family member 10.708
Tnfsf10tumor necrosis factor (ligand) superfamily, member 100.707
Ifi44interferon-induced protein 440.704
Il1rninterleukin 1 receptor antagonist0.704
H2-Q6histocompatibility 2, Q region locus 60.702
AxlAXL receptor tyrosine kinase0.701
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.696
Il2rginterleukin 2 receptor, gamma chain0.694
Inpp5dinositol polyphosphate-5-phosphatase D0.694
Parp9poly (ADP-ribose) polymerase family, member 90.675
Ifi47interferon gamma inducible protein 470.674
Itga4integrin alpha 40.670
H2-D1histocompatibility 2, D region locus 10.669
Ifit1interferon-induced protein with tetratricopeptide repeats 10.661
Ifih1interferon induced with helicase C domain 10.659
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.658
ItkIL2-inducible T-cell kinase0.658
Ms4a4cmembrane-spanning 4-domains, subfamily A, member 4C0.656
Ncr1natural cytotoxicity triggering receptor 10.656
Tlr2toll-like receptor 20.654
Rtp4receptor transporter protein 40.650
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.650
Sfpi1SFFV proviral integration 10.646
Ccr9chemokine (C-C motif) receptor 90.643
Ccl4chemokine (C-C motif) ligand 40.637
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RT1-BaRT1 class II, locus Ba0.752
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.599
Il1binterleukin 1 beta0.548
RT1-DMbRT1 class II, locus DMb0.530
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.482
Mmp12matrix metallopeptidase 120.479
Cxcl10chemokine (C-X-C motif) ligand 100.467
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.432
RT1-DaRT1 class II, locus Da0.429
Ccl4chemokine (C-C motif) ligand 40.397
Cd37CD37 molecule0.383
Ifitm3interferon induced transmembrane protein 30.349
Xcl1chemokine (C motif) ligand 10.337
Cfbcomplement factor B0.291
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.286
RT1-EC2RT1 class Ib, locus EC20.261
Cpceruloplasmin0.211
Hckhemopoietic cell kinase0.206
B2mbeta-2 microglobulin0.189
C1scomplement component 1, s subcomponent0.181
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.170
Cd14CD14 molecule0.169
Kcna3potassium voltage-gated channel, shaker-related subfamily, member 30.155
Ifit3interferon-induced protein with tetratricopeptide repeats 30.153
Lilrb3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.148
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.141
Casp1caspase 10.136
Tnftumor necrosis factor (TNF superfamily, member 2)0.134
Cxcl3chemokine (C-X-C motif) ligand 30.132
Kynukynureninase (L-kynurenine hydrolase)0.130
Lgals3bplectin, galactoside-binding, soluble, 3 binding protein0.126
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.126
Slc6a12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 120.124
Klrd1killer cell lectin-like receptor, subfamily D, member 10.123
Cd2Cd2 molecule0.123
Gckrglucokinase (hexokinase 4) regulator0.122
Dnase1l3deoxyribonuclease 1-like 30.122
Il6interleukin 60.120
Neurl3neuralized homolog 3 (Drosophila)0.114
Ccr5chemokine (C-C motif) receptor 50.103
Il2rbinterleukin 2 receptor, beta0.103
Grinaglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.101
Klrk1killer cell lectin-like receptor subfamily K, member 10.100
Pax8paired box 80.095
Scaf1SR-related CTD-associated factor 10.094
Tap1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.091
Lcn2lipocalin 20.091
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.089
Sellselectin L0.088
Nek9NIMA (never in mitosis gene a)- related kinase 90.088
Ncr1natural cytotoxicity triggering receptor 10.087
Prf1perforin 1 (pore forming protein)0.086
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.086
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.085
Gfi1growth factor independent 1 transcription repressor0.085
Ptbp1polypyrimidine tract binding protein 10.085
Il7rinterleukin 7 receptor0.084
Iappislet amyloid polypeptide0.083
Aqp9aquaporin 90.083
Casp12caspase 120.083
Csf1colony stimulating factor 1 (macrophage)0.082
Ifnginterferon gamma0.082
Gimap4GTPase, IMAP family member 40.081
Arf6ADP-ribosylation factor 60.081
Irf1interferon regulatory factor 10.081
Eif4heukaryotic translation initiation factor 4H0.081
Rgs1regulator of G-protein signaling 10.080
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.080
Apol3apolipoprotein L, 30.079
Gbp2guanylate binding protein 20.079
Stat3signal transducer and activator of transcription 30.079
LOC100364854similar to RIKEN cDNA A430107P09 gene-like0.079
Scarb1scavenger receptor class B, member 10.077
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.076
Edn1endothelin 10.076
Nkg7natural killer cell group 7 sequence0.076
LOC100363783rCG53773-like0.076
Notch2Notch homolog 2 (Drosophila)0.073
RT1-Db1RT1 class II, locus Db10.073
Oas1i2 ' -5 ' oligoadenylate synthetase 1I0.071
Gzmmgranzyme M (lymphocyte met-ase 1)0.069
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.069
Ahsgalpha-2-HS-glycoprotein0.069
Lig3ligase III, DNA, ATP-dependent0.068
C7complement component 70.067
Igsf6immunoglobulin superfamily, member 60.067
Cxcl9chemokine (C-X-C motif) ligand 90.067
Asgr2asialoglycoprotein receptor 20.066
Icam1intercellular adhesion molecule 10.066
C1rcomplement component 1, r subcomponent0.066
Adora3adenosine A3 receptor0.066
Tchhtrichohyalin0.065
RGD1564599RGD15645990.063
Hpgdshematopoietic prostaglandin D synthase0.063
Cpb1carboxypeptidase B1 (tissue)0.063
Vav1vav 1 guanine nucleotide exchange factor0.063
Phkg1phosphorylase kinase, gamma 10.061
Ifitm1interferon induced transmembrane protein 10.061
Il8rbinterleukin 8 receptor, beta0.061
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.061
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism