The network for 'response to metal ion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to metal ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.

NameDescriptionProbabilityFunc Analog Organism
JUNjun proto-oncogene0.999
MT1Hmetallothionein 1H0.987
FOSFBJ murine osteosarcoma viral oncogene homolog0.985
MT1Fmetallothionein 1F0.983
MT1Emetallothionein 1E0.980
BCL2B-cell CLL/lymphoma 20.978
MT2Ametallothionein 2A0.949
CFL1cofilin 1 (non-muscle)0.942
MAPK14mitogen-activated protein kinase 140.884
APPamyloid beta (A4) precursor protein0.861
TEKTEK tyrosine kinase, endothelial0.837
JUNBjun B proto-oncogene0.804
MT1Xmetallothionein 1X0.781
CDK2cyclin-dependent kinase 20.741
TP53tumor protein p530.717
DLG4discs, large homolog 4 (Drosophila)0.706
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.703
MAPK1mitogen-activated protein kinase 10.700
SP1Sp1 transcription factor0.663
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.644
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.629
BADBCL2-associated agonist of cell death0.622
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.591
FGAfibrinogen alpha chain0.535
CASP3caspase 3, apoptosis-related cysteine peptidase0.512
GSTM2glutathione S-transferase mu 2 (muscle)0.467
SMAD4SMAD family member 40.462
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.448
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.448
MT1Gmetallothionein 1G0.438
NR4A1nuclear receptor subfamily 4, group A, member 10.438
ANXA1annexin A10.430
NOSTRINnitric oxide synthase trafficker0.424
MAP2K1mitogen-activated protein kinase kinase 10.407
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.397
BCL2L1BCL2-like 10.381
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.381
LRP1low density lipoprotein receptor-related protein 10.360
APAF1apoptotic peptidase activating factor 10.348
DUSP1dual specificity phosphatase 10.347
ATF3activating transcription factor 30.340
BCL2L11BCL2-like 11 (apoptosis facilitator)0.339
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.337
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.333
MAPTmicrotubule-associated protein tau0.325
HNF4Ahepatocyte nuclear factor 4, alpha0.317
EP300E1A binding protein p3000.316
DLG1discs, large homolog 1 (Drosophila)0.313
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.308
SKP2S-phase kinase-associated protein 2 (p45)0.300
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.297
FASFas (TNF receptor superfamily, member 6)0.295
IRS1insulin receptor substrate 10.283
ESR1estrogen receptor 10.282
XIAPX-linked inhibitor of apoptosis0.274
MAP2K4mitogen-activated protein kinase kinase 40.269
PKP1plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)0.264
TTRtransthyretin0.260
APOEapolipoprotein E0.259
EGR1early growth response 10.257
GADD45Bgrowth arrest and DNA-damage-inducible, beta0.256
PCNAproliferating cell nuclear antigen0.256
HDAC4histone deacetylase 40.256
ATF2activating transcription factor 20.254
S100A14S100 calcium binding protein A140.253
TRPC4transient receptor potential cation channel, subfamily C, member 40.249
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.249
TXNthioredoxin0.248
PDCD6programmed cell death 60.247
SNTA1syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)0.242
PTENphosphatase and tensin homolog0.242
FGBfibrinogen beta chain0.239
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.235
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.233
SKP1S-phase kinase-associated protein 10.219
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 60.208
CASP9caspase 9, apoptosis-related cysteine peptidase0.205
PRDX1peroxiredoxin 10.201
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.200
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.197
TGFB1transforming growth factor, beta 10.192
TNNI1troponin I type 1 (skeletal, slow)0.189
CFLARCASP8 and FADD-like apoptosis regulator0.185
BHLHE40basic helix-loop-helix family, member e400.183
KRT5keratin 50.181
ZFYVE9zinc finger, FYVE domain containing 90.180
IER2immediate early response 20.179
SPRY4sprouty homolog 4 (Drosophila)0.179
CAV1caveolin 1, caveolae protein, 22kDa0.175
CYR61cysteine-rich, angiogenic inducer, 610.174
EGFRepidermal growth factor receptor0.171
DSG2desmoglein 20.169
CCNE1cyclin E10.167
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.167
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.161
FGGfibrinogen gamma chain0.158
TNNC1troponin C type 1 (slow)0.158
MCM6minichromosome maintenance complex component 60.158
TRIM63tripartite motif containing 630.154
PGK1phosphoglycerate kinase 10.154
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
cyp-35C1Protein CYP-35C10.073
egl-44Protein EGL-440.039
ncs-2Protein NCS-20.038
CELE_C29F7.2Protein C29F7.20.035
cyp-35A2Protein CYP-35A20.035
sqt-1Protein SQT-10.032
ina-1Protein INA-10.031
CELE_Y47H9C.7Protein Y47H9C.70.030
F14B8.2Protein F14B8.20.030
apy-1Protein APY-10.029
C03A3.2Protein C03A3.20.029
cyp-35A3Protein CYP-35A30.028
ttm-5Protein TTM-50.026
tps-1Protein TPS-10.025
F13H6.3Protein F13H6.30.024
unc-73Protein UNC-730.023
zig-9Protein ZIG-90.023
mig-2Protein MIG-20.022
syd-2Protein SYD-20.022
F47B8.4Protein F47B8.40.022
alx-1Protein ALX-10.022
lec-10Protein LEC-100.021
eps-8Protein EPS-80.020
egl-1Protein EGL-10.019
F13H10.4Protein F13H10.40.019
cyp-35A4Protein CYP-35A40.018
pkg-1Protein PKG-10.018
T16G1.6Protein T16G1.60.018
rig-6Protein RIG-60.018
egl-18Protein EGL-180.018
CELE_K09C4.5Protein K09C4.50.018
F44E7.4Protein F44E7.40.017
pmk-1Protein PMK-10.017
plc-3Protein PLC-30.017
nhr-45Protein NHR-450.017
goa-1Protein GOA-10.017
nhr-2Protein NHR-20.017
ipp-5Protein IPP-50.016
ugt-26Protein UGT-260.016
cdr-2Protein CDR-20.016
C37H5.2Protein C37H5.20.016
vav-1Protein VAV-10.016
clec-72Protein CLEC-720.016
CELE_F42F12.3Protein F42F12.30.016
cyp-35A5Protein CYP-35A50.016
K07C11.4Protein K07C11.40.016
nra-1Protein NRA-10.016
F37C4.5Protein F37C4.50.016
ftn-1Protein FTN-10.016
F35G2.2Protein F35G2.20.015
ugt-62Protein UGT-620.015
abu-12Protein ABU-120.015
toe-4Protein TOE-40.015
pmk-3Protein PMK-30.015
F22E12.1Protein F22E12.10.015
ztf-15Protein ZTF-150.015
snf-11Protein SNF-110.015
ppk-3Protein PPK-30.014
kcc-1Protein KCC-10.014
H03A11.2Protein H03A11.20.014
F09F7.5Protein F09F7.50.014
ced-3Protein CED-30.014
mrp-5Protein MRP-50.014
W04B5.3Protein W04B5.30.014
ddb-1Protein DDB-10.014
ugt-16Protein UGT-160.014
K10C2.1Protein K10C2.10.014
ftt-2Protein FTT-20.014
pgp-6Protein PGP-60.014
cec-1Protein CEC-10.014
cysl-1Protein CYSL-10.014
CELE_C08F11.3Protein C08F11.30.013
W01A11.1Protein W01A11.10.013
cdh-7Protein CDH-70.013
pal-1Protein PAL-10.013
unc-18Protein UNC-180.013
vab-1Protein VAB-10.013
gst-13Protein GST-130.013
dod-3Protein DOD-30.013
pqn-89Protein PQN-890.013
tag-147Protein TAG-1470.013
dpf-4Protein DPF-40.013
xpo-1Protein XPO-10.013
itr-1Protein ITR-10.013
tmc-2Protein TMC-20.013
npp-9Protein NPP-90.013
ugt-1Protein UGT-10.013
ugt-22Protein UGT-220.013
cpn-2Protein CPN-20.013
T14F9.2Protein T14F9.20.012
eat-6Protein EAT-60.012
tap-1Protein TAP-10.012
gst-5Protein GST-50.012
fkh-2Protein FKH-20.012
qns-1Protein QNS-10.012
unc-32Protein UNC-320.012
upp-1Protein UPP-10.012
svh-2Protein SVH-20.012
sma-5Protein SMA-50.012
T08G11.1Protein T08G11.10.012
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
bcl2B-cell leukemia/lymphoma 20.784
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.687
myod1myogenic differentiation 10.626
bcl2l1bcl2-like 10.619
mt2metallothionein 20.580
polr2dpolymerase (RNA) II (DNA directed) polypeptide D0.550
pcnaproliferating cell nuclear antigen0.515
ca2carbonic anhydrase II0.466
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.450
alcamaactivated leukocyte cell adhesion molecule a0.426
hspb1heat shock protein, alpha-crystallin-related, 10.323
limk2LIM domain kinase 20.304
trpv6transient receptor potential cation channel, subfamily V, member 60.289
cahzcarbonic anhydrase0.287
hsd17b2hydroxysteroid (17-beta) dehydrogenase 20.259
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.258
sod1superoxide dismutase 1, soluble0.256
mcl1amyeloid cell leukemia sequence 1a0.253
gadd45aagrowth arrest and DNA-damage-inducible, alpha, a0.226
mibp2muscle-specific beta 1 integrin binding protein 20.218
hspa5heat shock protein 50.215
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.204
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.203
copebcore promoter element binding protein0.194
si:dkey-236e20.2si:dkey-236e20.20.171
fabp7afatty acid binding protein 7, brain, a0.168
adrb2aadrenergic receptor, beta 2a0.168
gapdhglyceraldehyde-3-phosphate dehydrogenase0.162
cadm2acell adhesion molecule 2a0.159
inhbaainhibin, beta Aa0.157
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.148
bactin2bactin20.147
prnprs3prion protein, related sequence 30.143
csadcysteine sulfinic acid decarboxylase0.140
hsp90a.2heat shock protein 90-alpha 20.140
socs1suppressor of cytokine signaling 10.139
uxs1UDP-glucuronic acid decarboxylase 10.139
hand2heart and neural crest derivatives expressed transcript 20.138
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.136
atp1a1a.5ATPase, Na+/K+ transporting, alpha 1a.5 polypeptide0.133
epas1bendothelial PAS domain protein 1b0.132
atf3activating transcription factor 30.130
gata3GATA-binding protein 30.130
bbc3BCL2 binding component 30.128
bidaBH3 interacting domain death agonist0.127
sox9aSRY-box containing gene 9a0.125
drd2bdopamine receptor D2b0.125
trpm7transient receptor potential cation channel, subfamily M, member 70.121
cbr1lcarbonyl reductase 1-like0.118
hsp47heat shock protein 470.118
alas2aminolevulinate, delta-, synthetase 20.113
dag1dystroglycan 10.113
cav1caveolin 10.110
ckbbcreatine kinase, brain b0.110
clockclock0.108
acvr2aactivin receptor IIa0.101
acadlacyl-Coenzyme A dehydrogenase, long chain0.100
mapk3mitogen-activated protein kinase 30.100
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.098
cxadrcoxsackie virus and adenovirus receptor0.098
inhainhibin, alpha0.095
mtpmicrosomal triglyceride transfer protein0.094
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.094
cyp3c1cytochrome P450, family 3, subfamily c, polypeptide 10.093
nrg1neuregulin 10.092
mapk6mitogen-activated protein kinase 60.091
sod2superoxide dismutase 2, mitochondrial0.089
pdlim4PDZ and LIM domain 40.088
mapk7mitogen-activated protein kinase 70.085
si:rp71-39b20.7si:rp71-39b20.70.084
rpl13aribosomal protein L13a0.084
slc39a1solute carrier family 39 (zinc transporter), member 10.084
cd63Cd63 antigen0.083
ocrloculocerebrorenal syndrome of Lowe0.083
nap1l1nucleosome assembly protein 1, like 10.077
tspotranslocator protein0.076
fbln4fibulin 40.075
oprk1opioid receptor, kappa 10.074
junjun proto-oncogene0.074
tgfbr2transforming growth factor, beta receptor II0.073
grin1aglutamate receptor, ionotropic, N-methyl D-aspartate 1a0.073
klf4aKruppel-like transcription factor 4a0.073
mmp13amatrix metalloproteinase 13a0.071
aldh1a2aldehyde dehydrogenase 1 family, member A20.071
tmprss4atransmembrane protease, serine 4a0.071
pcdh2acprotocadherin 2 alpha c0.070
zgc:136878zgc:1368780.069
mcl1bmyeloid cell leukemia sequence 1b0.068
atp6v1e1bATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b0.068
comtacatechol-O-methyltransferase a0.068
keap1akelch-like ECH-associated protein 1a0.068
gfapglial fibrillary acidic protein0.067
mdm2transformed 3T3 cell double minute 2 homolog (mouse)0.067
sb:cb1058sb:cb10580.066
chrm2acholinergic receptor, muscarinic 2a0.065
vdravitamin D receptor a0.064
notch2notch homolog 20.063
crygm2d1crystallin, gamma M2d10.063
tlr3toll-like receptor 30.062
mvpmajor vault protein0.061
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rac1CG2248 gene product from transcript CG2248-RA0.924
Cdc42CG12530 gene product from transcript CG12530-RA0.447
SodSuperoxide dismutase0.439
TpiTriose phosphate isomerase0.386
cicubitus interruptus0.328
Fer1HCHFerritin 1 heavy chain homologue0.284
ptcpatched0.265
Stat92ESignal-transducer and activator of transcription protein at 92E0.252
PHGPxCG12013 gene product from transcript CG12013-RC0.242
Gapdh2Glyceraldehyde 3 phosphate dehydrogenase 20.231
NlpNucleoplasmin0.206
Cyp12a4CG6042 gene product from transcript CG6042-RA0.199
Gapdh1Glyceraldehyde 3 phosphate dehydrogenase 10.199
trioCG18214 gene product from transcript CG18214-RA0.192
Dcr-2Dicer-20.189
Src42ASrc oncogene at 42A0.189
Ugt35aUDP-glycosyltransferase 35a0.168
Pink1PTEN-induced putative kinase 10.146
AldhAldehyde dehydrogenase0.144
NNotch0.135
EnoEnolase0.131
mysmyospheroid0.125
LamCLamin C0.109
CG2107CG2107 gene product from transcript CG2107-RA0.102
Trx-2thioredoxin-20.102
Jafrac1thioredoxin peroxidase 10.095
AdhAlcohol dehydrogenase0.093
CG1927CG1927 gene product from transcript CG1927-RA0.091
TequilaCG4821 gene product from transcript CG4821-RE0.090
CatCatalase0.090
ifinflated0.088
NPFR1neuropeptide F receptor0.084
Ork1Open rectifier K[+] channel 10.083
bskbasket0.082
Cyp6a21CG10247 gene product from transcript CG10247-RA0.077
JhI-26Juvenile hormone-inducible protein 260.074
mthmethuselah0.073
par-1CG8201 gene product from transcript CG8201-RA0.073
CG12171CG12171 gene product from transcript CG12171-RA0.072
Mpk2CG5475 gene product from transcript CG5475-RB0.071
smt3CG4494 gene product from transcript CG4494-RA0.071
Jheh2Juvenile hormone epoxide hydrolase 20.070
Rya-r44FRyanodine receptor 44F0.070
Cyp6a2Cytochrome P450-6a20.069
CG6834CG6834 gene product from transcript CG6834-RA0.066
sloslowpoke0.066
kaykayak0.066
l(2)05510lethal (2) 055100.064
Got2Glutamate oxaloacetate transaminase 20.063
CG10863CG10863 gene product from transcript CG10863-RA0.062
S6kRPS6-p70-protein kinase0.061
Tsp29FbTetraspanin 29Fb0.060
Osi6Osiris 60.059
miltmilton0.059
CG17325CG17325 gene product from transcript CG17325-RA0.058
Vha16Vacuolar H[+] ATPase 16kD subunit0.056
TotATurandot A0.055
slowslowdown0.054
drkdownstream of receptor kinase0.052
panpangolin0.052
blowblown fuse0.050
CG10638CG10638 gene product from transcript CG10638-RA0.049
RalaRas-related protein0.049
rolsrolling pebbles0.048
kstkarst0.048
Dsor1Downstream of raf10.047
MTF-1Metal response element-binding Transcription Factor-10.046
ImpL3Ecdysone-inducible gene L30.045
CG4860CG4860 gene product from transcript CG4860-RA0.044
Cyp6a9Cytochrome P450-6a90.044
Mekk1CG7717 gene product from transcript CG7717-RB0.043
Chd64CG14996 gene product from transcript CG14996-RB0.042
Cyp6g1CG8453 gene product from transcript CG8453-RA0.042
lolalongitudinals lacking0.042
CG15611CG15611 gene product from transcript CG15611-RB0.041
Cyp6a23CG10242 gene product from transcript CG10242-RA0.041
alpha-Est7alpha-Esterase-70.040
NLazNeural Lazarillo0.039
Fer2LCHFerritin 2 light chain homologue0.038
CG5362CG5362 gene product from transcript CG5362-RA0.036
AblAbl tyrosine kinase0.036
plepale0.035
Tak1TGF-beta activated kinase 10.034
EcREcdysone receptor0.034
Cg25CCollagen type IV0.033
Rab11Rab-protein 110.033
spispitz0.033
CG11897CG11897 gene product from transcript CG11897-RA0.033
RelRelish0.033
cltcricklet0.033
blwbellwether0.033
eIF4Geukaryotic translation initiation factor 4G0.032
ArgkArginine kinase0.031
ClkClock0.031
CG2233CG2233 gene product from transcript CG2233-RA0.031
sinaseven in absentia0.031
CG2852CG2852 gene product from transcript CG2852-RA0.030
CG11674CG11674 gene product from transcript CG11674-RA0.029
PGRP-LEPeptidoglycan recognition protein LE0.029
Yp3Yolk protein 30.029
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.963
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.911
Apoeapolipoprotein E0.855
Egfrepidermal growth factor receptor0.832
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.831
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.825
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.734
Lyz2lysozyme 20.664
Mapk14mitogen-activated protein kinase 140.654
Cps1carbamoyl-phosphate synthetase 10.589
Hbb-b1hemoglobin, beta adult major chain0.576
Emx1empty spiracles homolog 1 (Drosophila)0.572
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.571
Tgfbr2transforming growth factor, beta receptor II0.567
Cd44CD44 antigen0.566
Krt72-pskeratin 72, pseudogene0.540
Cyp3a11cytochrome P450, family 3, subfamily a, polypeptide 110.529
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.526
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.507
FosFBJ osteosarcoma oncogene0.506
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.486
Ptgs2prostaglandin-endoperoxide synthase 20.480
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.477
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.468
Taglntransgelin0.467
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.449
Id3inhibitor of DNA binding 30.437
Nr5a2nuclear receptor subfamily 5, group A, member 20.401
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.389
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.386
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.378
S100a9S100 calcium binding protein A9 (calgranulin B)0.367
S100a8S100 calcium binding protein A8 (calgranulin A)0.367
Mapk8mitogen-activated protein kinase 80.362
Lepleptin0.362
Cyp2b9cytochrome P450, family 2, subfamily b, polypeptide 90.353
Atf2activating transcription factor 20.345
Prkceprotein kinase C, epsilon0.341
Tgfbr1transforming growth factor, beta receptor I0.341
Trp53transformation related protein 530.328
Neurod1neurogenic differentiation 10.328
Ccl2chemokine (C-C motif) ligand 20.315
Klklotho0.315
Ptprcprotein tyrosine phosphatase, receptor type, C0.311
Id1inhibitor of DNA binding 10.309
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.307
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.288
Dlg4discs, large homolog 4 (Drosophila)0.284
Abcc6ATP-binding cassette, sub-family C (CFTR/MRP), member 60.279
Ahsgalpha-2-HS-glycoprotein0.278
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.278
Atf3activating transcription factor 30.276
Pitx2paired-like homeodomain transcription factor 20.276
Bglapbone gamma carboxyglutamate protein0.261
Smad3MAD homolog 3 (Drosophila)0.258
Csf1colony stimulating factor 1 (macrophage)0.250
Apobapolipoprotein B0.243
Uoxurate oxidase0.232
Gcgrglucagon receptor0.232
Gria2glutamate receptor, ionotropic, AMPA2 (alpha 2)0.232
Ascl1achaete-scute complex homolog 1 (Drosophila)0.231
Myf5myogenic factor 50.231
Akr1c6aldo-keto reductase family 1, member C60.228
Rdh7retinol dehydrogenase 70.226
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.222
Nr1i3nuclear receptor subfamily 1, group I, member 30.218
Otcornithine transcarbamylase0.217
Shc3src homology 2 domain-containing transforming protein C30.217
Apoa1apolipoprotein A-I0.217
JunJun oncogene0.216
Tgfb1transforming growth factor, beta 10.214
Mbl2mannose-binding lectin (protein C) 20.212
Ces1ccarboxylesterase 1C0.210
Tlr4toll-like receptor 40.209
Tcf4transcription factor 40.208
Gja3gap junction protein, alpha 30.208
Il2rginterleukin 2 receptor, gamma chain0.207
Hrghistidine-rich glycoprotein0.203
Albalbumin0.198
Neurod4neurogenic differentiation 40.195
Ttrtransthyretin0.195
Hnf4ahepatic nuclear factor 4, alpha0.193
Notch2Notch gene homolog 2 (Drosophila)0.193
Hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 70.184
Cd19CD19 antigen0.184
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.183
Gstm1glutathione S-transferase, mu 10.179
Pcnaproliferating cell nuclear antigen0.179
Pitx1paired-like homeodomain transcription factor 10.179
Tcf3transcription factor 30.176
CrpC-reactive protein, pentraxin-related0.172
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.171
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.169
Aadacarylacetamide deacetylase (esterase)0.167
Brca1breast cancer 10.167
Gja1gap junction protein, alpha 10.166
Foxc1forkhead box C10.166
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.165
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.165
Slc40a1solute carrier family 40 (iron-regulated transporter), member 10.161
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.916
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.876
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.837
Slc14a2solute carrier family 14 (urea transporter), member 20.811
Lgals3lectin, galactoside-binding, soluble, 30.733
Gstm1glutathione S-transferase mu 10.712
Krt5keratin 50.705
Fgafibrinogen alpha chain0.673
Ephx1epoxide hydrolase 1, microsomal0.668
Mettl7bmethyltransferase like 7B0.617
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.586
Cps1carbamoyl-phosphate synthetase 10.570
Ifitm3interferon induced transmembrane protein 30.564
Dhfrdihydrofolate reductase0.548
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.542
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.533
Haao3-hydroxyanthranilate 3,4-dioxygenase0.529
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.509
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.505
Foxa1forkhead box A10.502
Anxa2annexin A20.490
Mgst1microsomal glutathione S-transferase 10.488
Hpxhemopexin0.482
Cd80Cd80 molecule0.476
Anxa5annexin A50.474
Pla2g2cphospholipase A2, group IIC0.469
Apoc4apolipoprotein C-IV0.456
Cd14CD14 molecule0.442
Il8rbinterleukin 8 receptor, beta0.439
Tnrtenascin R0.436
Ptprhprotein tyrosine phosphatase, receptor type, H0.433
Ahsgalpha-2-HS-glycoprotein0.432
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.424
Pnlippancreatic lipase0.417
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.406
Cyb5acytochrome b5 type A (microsomal)0.405
Prdx2peroxiredoxin 20.403
COX2COXII0.400
Cyp2f4cytochrome P450, family 2, subfamily f, polypeptide 40.400
Cnga3cyclic nucleotide gated channel alpha 30.391
S100a6S100 calcium binding protein A60.389
Mmp3matrix metallopeptidase 30.382
Plauplasminogen activator, urokinase0.380
Aldoaaldolase A, fructose-bisphosphate0.379
Agxt2alanine-glyoxylate aminotransferase 20.377
Sult1a1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 10.376
Aqp8aquaporin 80.371
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.367
Inhbeinhibin beta E0.363
Myl7myosin, light chain 7, regulatory0.359
Ccr3chemokine (C-C motif) receptor 30.357
Gckglucokinase0.352
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.352
Il12binterleukin 12B0.350
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.343
Gria2glutamate receptor, ionotropic, AMPA 20.341
Dlg4discs, large homolog 4 (Drosophila)0.340
Gabrr1gamma-aminobutyric acid (GABA) receptor, rho 10.338
Gstp1glutathione S-transferase pi 10.336
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.336
Crxcone-rod homeobox0.335
Pklrpyruvate kinase, liver and RBC0.335
Nr4a3nuclear receptor subfamily 4, group A, member 30.333
Timp1TIMP metallopeptidase inhibitor 10.330
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.330
Hspb1heat shock protein 10.329
Zfp37zinc finger protein 370.327
Akr1c14aldo-keto reductase family 1, member C140.327
Gja4gap junction protein, alpha 40.326
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.324
Espnespin0.320
Mmp8matrix metallopeptidase 80.319
Vimvimentin0.317
Fbp1fructose-1,6-bisphosphatase 10.316
COX1cytochrome c oxidase subunit 10.316
CartptCART prepropeptide0.315
Ubbubiquitin B0.315
Fn1fibronectin 10.315
Pygmphosphorylase, glycogen, muscle0.315
Col10a1collagen, type X, alpha 10.312
Ceacam1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.309
Actbactin, beta0.309
Cd40lgCD40 ligand0.306
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.304
Slc30a2solute carrier family 30 (zinc transporter), member 20.304
Pla2g1bphospholipase A2, group IB, pancreas0.303
Apcsamyloid P component, serum0.299
C1scomplement component 1, s subcomponent0.295
Nmuneuromedin U0.294
Slc6a2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.293
Capn8calpain 80.291
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.291
RorbRAR-related orphan receptor B0.286
Arpc1bactin related protein 2/3 complex, subunit 1B0.285
Slc4a2solute carrier family 4 (anion exchanger), member 20.285
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.280
Agtr2angiotensin II receptor, type 20.278
Gp2glycoprotein 2 (zymogen granule membrane)0.276
Timp2TIMP metallopeptidase inhibitor 20.274
Cgaglycoprotein hormones, alpha polypeptide0.273
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
AFT1Aft1p0.140
TSA2Tsa2p0.100
AQY2Aqy2p0.079
NRG1Nrg1p0.065
CKS1Cks1p0.059
RPN4Rpn4p0.056
YCR102Chypothetical protein0.056
MIG1Mig1p0.047
CUP9Cup9p0.045
HSF1Hsf1p0.039
CLB3Clb3p0.038
CMK1Cmk1p0.038
CDC28Cdc28p0.036
CLB4Clb4p0.036
MIG2Mig2p0.035
CNB1Cnb1p0.035
SIT1Sit1p0.035
ALY1Aly1p0.033
SHE3She3p0.032
FKH1Fkh1p0.032
YCF1Ycf1p0.031
TOM1Tom1p0.030
CDC4Cdc4p0.030
TBS1Tbs1p0.029
YLR108Chypothetical protein0.029
TSA1Tsa1p0.028
CPR1Cpr1p0.027
PMC1Pmc1p0.027
CMP2Cmp2p0.027
YNL035Chypothetical protein0.026
MSN4Msn4p0.026
GLN3Gln3p0.026
CLB1Clb1p0.026
HST1Hst1p0.026
TDH2Tdh2p0.024
GFA1Gfa1p0.024
FMP40Fmp40p0.024
NUP157Nup157p0.024
VAC7Vac7p0.023
PHO80Pho80p0.023
KIC1Kic1p0.023
GAD1Gad1p0.023
RIM101Rim101p0.023
CMD1Cmd1p0.022
PGM3Pgm3p0.022
PTM1Ptm1p0.022
CAK1Cak1p0.021
YPL014Whypothetical protein0.021
SEC16Sec16p0.021
STR3Str3p0.020
TPA1Tpa1p0.020
TUS1Tus1p0.020
CLN2Cln2p0.020
ARP2Arp2p0.020
YCK2Yck2p0.020
IRA1Ira1p0.020
RSN1Rsn1p0.020
HXT3Hxt3p0.020
GDI1Gdi1p0.019
MOB1Mob1p0.019
OTU1Otu1p0.018
KSS1Kss1p0.018
CDC6Cdc6p0.018
NUM1Num1p0.018
HOR2Hor2p0.018
ROX1Rox1p0.018
YKR075Chypothetical protein0.018
UBP7Ubp7p0.018
IMD2Imd2p0.018
RAD51Rad51p0.018
VID24Vid24p0.017
MRL1Mrl1p0.017
PRD1Prd1p0.017
GAL7Gal7p0.017
SYG1Syg1p0.017
NHX1Nhx1p0.017
GSP2Gsp2p0.017
GLR1Glr1p0.017
ECM30Ecm30p0.017
DSS4Dss4p0.017
YGR017Whypothetical protein0.017
ADP1Adp1p0.017
COT1Cot1p0.017
RLM1Rlm1p0.017
TPI1Tpi1p0.016
GPT2Gpt2p0.016
NCR1Ncr1p0.016
HOG1Hog1p0.016
HMS1Hms1p0.016
SMP1Smp1p0.016
CSR2Csr2p0.016
RAD28Rad28p0.016
YLR460Chypothetical protein0.016
KTR5Ktr5p0.016
MIG3Mig3p0.016
CRR1Crr1p0.016
NET1Net1p0.016
TIP41Tip41p0.016
PHM8Phm8p0.016
ZAP1Zap1p0.016