The network for 'negative regulation of protein deubiquitination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of protein deubiquitination

Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.

NameDescriptionProbabilityFunc Analog Organism
MED15mediator complex subunit 150.899
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.766
ZNF263zinc finger protein 2630.480
FASFas (TNF receptor superfamily, member 6)0.452
TRIM5tripartite motif containing 50.386
CASP8caspase 8, apoptosis-related cysteine peptidase0.368
FADDFas (TNFRSF6)-associated via death domain0.352
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.309
DAXXdeath-domain associated protein0.302
IFI16interferon, gamma-inducible protein 160.241
RBCK1RanBP-type and C3HC4-type zinc finger containing 10.237
TRIM21tripartite motif containing 210.211
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.144
SP100SP100 nuclear antigen0.104
ZNF473zinc finger protein 4730.093
MCOLN1mucolipin 10.083
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.079
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.078
PMLpromyelocytic leukemia0.074
STIP1stress-induced-phosphoprotein 10.071
BAG2BCL2-associated athanogene 20.066
HSPA8heat shock 70kDa protein 80.059
DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.050
GBP2guanylate binding protein 2, interferon-inducible0.042
TRIM52tripartite motif containing 520.042
TRIM35tripartite motif containing 350.041
UBE2Uubiquitin-conjugating enzyme E2U (putative)0.039
PSEN2presenilin 2 (Alzheimer disease 4)0.036
RNF5ring finger protein 50.035
NMIN-myc (and STAT) interactor0.034
TRIM34tripartite motif containing 340.033
TRIM8tripartite motif containing 80.031
TRIM6-TRIM34TRIM6-TRIM34 readthrough0.030
CFLARCASP8 and FADD-like apoptosis regulator0.030
XIAPX-linked inhibitor of apoptosis0.029
TNFSF10tumor necrosis factor (ligand) superfamily, member 100.028
IRF2interferon regulatory factor 20.028
PLSCR1phospholipid scramblase 10.026
BAG1BCL2-associated athanogene0.026
TRIM41tripartite motif containing 410.025
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.025
UBQLN1ubiquilin 10.025
PSEN1presenilin 10.024
ATXN3ataxin 30.024
CASP10caspase 10, apoptosis-related cysteine peptidase0.023
CTSOcathepsin O0.021
TRAF3TNF receptor-associated factor 30.021
TRIM26tripartite motif containing 260.020
MR1major histocompatibility complex, class I-related0.019
IFI44interferon-induced protein 440.019
MAGEF1melanoma antigen family F, 10.019
TMCO6transmembrane and coiled-coil domains 60.018
NDUFA4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa0.018
SREBF1sterol regulatory element binding transcription factor 10.017
TRIM6tripartite motif containing 60.017
ANXA1annexin A10.017
MAGEA1melanoma antigen family A, 1 (directs expression of antigen MZ2-E)0.017
PIK3C2Bphosphoinositide-3-kinase, class 2, beta polypeptide0.017
ARIH2ariadne homolog 2 (Drosophila)0.017
ATP5JATP synthase, H+ transporting, mitochondrial Fo complex, subunit F60.017
ZCCHC6zinc finger, CCHC domain containing 60.016
TRADDTNFRSF1A-associated via death domain0.016
UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.016
ZBTB8Azinc finger and BTB domain containing 8A0.015
RIC8Aresistance to inhibitors of cholinesterase 8 homolog A (C. elegans)0.015
DAD1defender against cell death 10.015
IL15interleukin 150.015
DTX3Ldeltex 3-like (Drosophila)0.015
TRIM4tripartite motif containing 40.015
PLCD4phospholipase C, delta 40.015
MKRN3makorin ring finger protein 30.014
RASSF1Ras association (RalGDS/AF-6) domain family member 10.014
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.014
PHF11PHD finger protein 110.014
ZNRF1zinc and ring finger 10.014
BAG3BCL2-associated athanogene 30.014
ELK1ELK1, member of ETS oncogene family0.014
TDRD7tudor domain containing 70.014
RNF31ring finger protein 310.014
OSBP2oxysterol binding protein 20.013
UBTD1ubiquitin domain containing 10.013
USP4ubiquitin specific peptidase 4 (proto-oncogene)0.013
RNF166ring finger protein 1660.013
SDSLserine dehydratase-like0.013
TRIM32tripartite motif containing 320.013
UBE2Zubiquitin-conjugating enzyme E2Z0.013
MUL1mitochondrial E3 ubiquitin protein ligase 10.012
RNF25ring finger protein 250.012
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.012
E4F1E4F transcription factor 10.012
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.012
ZNF202zinc finger protein 2020.012
HK2hexokinase 20.012
KRT18keratin 180.012
UBOX5U-box domain containing 50.012
IFIT5interferon-induced protein with tetratricopeptide repeats 50.012
OAS22'-5'-oligoadenylate synthetase 2, 69/71kDa0.011
TUBGCP4tubulin, gamma complex associated protein 40.011
PRKCAprotein kinase C, alpha0.011
HSPA1Bheat shock 70kDa protein 1B0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism