The network for 'negative regulation of gliogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of gliogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.

NameDescriptionProbabilityFunc Analog Organism
BTRCbeta-transducin repeat containing1.000
SMAD7SMAD family member 70.999
SMAD4SMAD family member 40.997
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.992
POU3F2POU class 3 homeobox 20.990
PAX3paired box 30.987
YAP1Yes-associated protein 10.982
SMAD3SMAD family member 30.981
SCHIP1schwannomin interacting protein 10.934
CUL1cullin 10.920
FBXW11F-box and WD repeat domain containing 110.904
JAG1jagged 10.880
ZFYVE9zinc finger, FYVE domain containing 90.818
AMOTL1angiomotin like 10.814
BMP7bone morphogenetic protein 70.797
SMURF2SMAD specific E3 ubiquitin protein ligase 20.775
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.727
SKILSKI-like oncogene0.712
CXXC5CXXC finger protein 50.702
POU5F1POU class 5 homeobox 10.665
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.649
WWP2WW domain containing E3 ubiquitin protein ligase 20.633
FGF1fibroblast growth factor 1 (acidic)0.622
NOTCH3notch 30.617
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.543
NR4A1nuclear receptor subfamily 4, group A, member 10.516
TNRC6Atrinucleotide repeat containing 6A0.505
NEDD9neural precursor cell expressed, developmentally down-regulated 90.467
SMAD1SMAD family member 10.449
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.445
MEOX2mesenchyme homeobox 20.421
AMOTL2angiomotin like 20.418
MAXMYC associated factor X0.413
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.390
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.384
FOXD3forkhead box D30.368
SNAI1snail homolog 1 (Drosophila)0.332
CMTM6CKLF-like MARVEL transmembrane domain containing 60.326
SKP1S-phase kinase-associated protein 10.314
MARCKSL1MARCKS-like 10.299
TCF4transcription factor 40.267
CDC34cell division cycle 34 homolog (S. cerevisiae)0.255
OLIG2oligodendrocyte lineage transcription factor 20.249
FGFR2fibroblast growth factor receptor 20.246
MAML1mastermind-like 1 (Drosophila)0.234
GLIS2GLIS family zinc finger 20.234
XIAPX-linked inhibitor of apoptosis0.230
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.227
LATS1LATS, large tumor suppressor, homolog 1 (Drosophila)0.208
SALL2sal-like 2 (Drosophila)0.204
SMAD5SMAD family member 50.203
HIST1H3Bhistone cluster 1, H3b0.197
NFIXnuclear factor I/X (CCAAT-binding transcription factor)0.186
STK38Lserine/threonine kinase 38 like0.185
EIF2C2eukaryotic translation initiation factor 2C, 20.178
AXIN1axin 10.173
HEY1hairy/enhancer-of-split related with YRPW motif 10.166
BMP2bone morphogenetic protein 20.164
SOX9SRY (sex determining region Y)-box 90.157
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.148
PSEN1presenilin 10.148
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.146
WEE1WEE1 homolog (S. pombe)0.144
ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix protein0.139
NCOR1nuclear receptor corepressor 10.139
F3coagulation factor III (thromboplastin, tissue factor)0.136
IFNAR1interferon (alpha, beta and omega) receptor 10.135
TAL1T-cell acute lymphocytic leukemia 10.132
MYOD1myogenic differentiation 10.132
FBLN1fibulin 10.131
PTPN14protein tyrosine phosphatase, non-receptor type 140.123
FOXG1forkhead box G10.121
MSX1msh homeobox 10.115
CDH5cadherin 5, type 2 (vascular endothelium)0.111
SKIv-ski sarcoma viral oncogene homolog (avian)0.110
FGAfibrinogen alpha chain0.110
FBXW7F-box and WD repeat domain containing 70.109
SOX11SRY (sex determining region Y)-box 110.109
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.108
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.106
HIVEP1human immunodeficiency virus type I enhancer binding protein 10.101
EEF2Keukaryotic elongation factor-2 kinase0.100
MMP16matrix metallopeptidase 16 (membrane-inserted)0.099
EIF2C1eukaryotic translation initiation factor 2C, 10.098
SMURF1SMAD specific E3 ubiquitin protein ligase 10.094
GFAPglial fibrillary acidic protein0.092
HIST1H4Fhistone cluster 1, H4f0.092
F7coagulation factor VII (serum prothrombin conversion accelerator)0.087
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.087
APCadenomatous polyposis coli0.086
DLL1delta-like 1 (Drosophila)0.085
SALL3sal-like 3 (Drosophila)0.082
TRIM9tripartite motif containing 90.080
FERMT2fermitin family member 20.079
ASCL1achaete-scute complex homolog 1 (Drosophila)0.079
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.078
INHBBinhibin, beta B0.078
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
her4.2hairy-related 4.20.956
ascl1aachaete-scute complex-like 1a (Drosophila)0.799
notch3notch homolog 30.724
her12hairy-related 120.718
pcdh17protocadherin 170.502
olig2oligodendrocyte lineage transcription factor 20.448
lhx1aLIM homeobox 1a0.418
ascl1bachaete-scute complex-like 1b (Drosophila)0.405
foxp2forkhead box P20.403
dmrta2doublesex and mab-3 related transcription factor like family A20.394
nr2e1nuclear receptor subfamily 2, group E, member 10.391
dlx1adistal-less homeobox gene 1a0.364
otx1borthodenticle homolog 1b0.360
otpborthopedia homolog b0.336
lfnglunatic fringe homolog0.333
sox3SRY-box containing gene 30.324
rspo3R-spondin 3 homolog (Xenopus laevis)0.309
barhl2BarH-like 20.304
dbx1adeveloping brain homeobox 1a0.283
efnb2aephrin B2a0.258
insm1binsulinoma-associated 1b0.257
rfx2regulatory factor X, 2 (influences HLA class II expression)0.233
zic4zic family member 40.221
osr1odd-skipped related 1 (Drosophila)0.219
insm1ainsulinoma-associated 1a0.192
olig4oligodendrocyte transcription factor 40.187
pitx3paired-like homeodomain transcription factor 30.180
sfrp5secreted frizzled-related protein 50.159
her15.1hairy and enhancer of split-related 15.10.159
tpbgltrophoblast glycoprotein-like0.158
epha4aeph receptor A4a0.157
fzd7afrizzled homolog 7a0.151
hey1hairy/enhancer-of-split related with YRPW motif 10.139
cd99l2CD99 antigen-like 20.137
pou5f1POU domain, class 5, transcription factor 10.133
pax6apaired box gene 6a0.130
sox21bSRY-box containing gene 21 b0.127
sox2SRY-box containing gene 20.117
emx2empty spiracles homeobox 20.113
nog2noggin 20.110
pvrl1bpoliovirus receptor-related 1b0.106
pax6bpaired box gene 6b0.106
vsx2visual system homeobox 20.098
meis2.2myeloid ecotropic viral integration site 2.20.098
fezf2FEZ family zinc finger 20.097
nova2neuro-oncological ventral antigen 20.097
gli3GLI-Kruppel family member GLI30.095
neurod4neurogenic differentiation 40.095
nf1bneurofibromin 1b0.093
cnr1cannabinoid receptor 10.093
arxaristaless related homeobox0.093
bonbonnie and clyde0.092
nadl1.2neural adhesion molecule L1.20.091
olig3oligodendrocyte transcription factor 30.089
pou3f1POU class 3 homeobox 10.088
nf1aneurofibromin 1a0.087
aplnrbapelin receptor b0.086
msi1musashi homolog 1 (Drosophila)0.083
egr1early growth response 10.082
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.081
jag1ajagged 1a0.080
dnmt8DNA (cytosine-5-)-methyltransferase 80.080
cdh2cadherin 2, neuronal0.077
dact2dapper homolog 2, antagonist of beta-catenin (xenopus)0.077
nr4a3nuclear receptor subfamily 4, group A, member 30.076
antxr1anthrax toxin receptor 10.076
hnf1bbHNF1 homeobox Bb0.076
jag2jagged 20.076
dlx2bdistal-less homeobox gene 2b0.074
gbx1gastrulation brain homeobox 10.071
lrrn1leucine rich repeat neuronal 10.071
foxb1.2forkhead box B1.20.070
sim1asingle-minded homolog 1a (Drosophila)0.069
rasl11bRAS-like, family 11, member B0.068
sox19aSRY-box containing gene 19a0.067
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.066
cnot6CCR4-NOT transcription complex, subunit 60.066
sox17SRY-box containing gene 170.065
cdx4caudal type homeo box transcription factor 40.065
clstn1calsyntenin 10.065
LOC100007758novel protein similar to vertebrate SLIT and NTRK-like family, member 3 (SLITRK3)0.064
nr2f2nuclear receptor subfamily 2, group F, member 20.064
msxcmuscle segment homeobox C0.063
nr4a2bnuclear receptor subfamily 4, group A, member 2b0.063
glra4aglycine receptor, alpha 4a0.060
ptrfbpolymerase I and transcript release factor b0.060
siah1seven in absentia homolog 1 (Drosophila)0.058
otx2orthodenticle homolog 20.057
mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.057
wisp1bWNT1 inducible signaling pathway protein 1b0.057
zic1zic family member 1 (odd-paired homolog, Drosophila)0.055
celf1cugbp, Elav-like family member 10.054
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
HLHm7E(spl) region transcript m70.935
E(spl)Enhancer of split0.906
HLHmgammaE(spl) region transcript mgamma0.892
HLHmdeltaE(spl) region transcript mdelta0.397
HLHmbetaE(spl) region transcript mbeta0.285
HLHm5E(spl) region transcript m50.146
HLHm3E(spl) region transcript m30.133
malphaE(spl) region transcript malpha0.064
m2E(spl) region transcript m20.045
MadMothers against dpp0.032
cicubitus interruptus0.026
m4E(spl) region transcript m40.022
fz2frizzled 20.017
pashapartner of drosha0.017
Akt1CG4006 gene product from transcript CG4006-RA0.016
CG5794CG5794 gene product from transcript CG5794-RB0.014
salmspalt major0.013
TolloCG6890 gene product from transcript CG6890-RA0.011
Tsc1CG6147 gene product from transcript CG6147-RA0.011
aopanterior open0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.998
Emx1empty spiracles homolog 1 (Drosophila)0.997
Sox9SRY-box containing gene 90.994
Ctnnb1catenin (cadherin associated protein), beta 10.992
Pax3paired box gene 30.986
Shhsonic hedgehog0.981
Isl1ISL1 transcription factor, LIM/homeodomain0.979
Fgfr1fibroblast growth factor receptor 10.946
Bmp4bone morphogenetic protein 40.924
Hes1hairy and enhancer of split 1 (Drosophila)0.910
Gli3GLI-Kruppel family member GLI30.896
Otx2orthodenticle homolog 2 (Drosophila)0.885
Hand2heart and neural crest derivatives expressed transcript 20.875
Prrx1paired related homeobox 10.850
Tcfap2atranscription factor AP-2, alpha0.847
Nf1neurofibromatosis 10.845
Dlx1distal-less homeobox 10.842
Foxc1forkhead box C10.828
Pax6paired box gene 60.822
Hand1heart and neural crest derivatives expressed transcript 10.815
Eya1eyes absent 1 homolog (Drosophila)0.807
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.796
Msx1homeobox, msh-like 10.785
Trp53transformation related protein 530.774
Sox2SRY-box containing gene 20.757
Id3inhibitor of DNA binding 30.753
Fgf8fibroblast growth factor 80.737
Retret proto-oncogene0.735
Emx2empty spiracles homolog 2 (Drosophila)0.732
Apcadenomatosis polyposis coli0.727
Id1inhibitor of DNA binding 10.614
Meox2mesenchyme homeobox 20.610
Dlx2distal-less homeobox 20.560
Alx4aristaless-like homeobox 40.523
Cdkn1bcyclin-dependent kinase inhibitor 1B0.504
Pitx2paired-like homeodomain transcription factor 20.484
Ptch1patched homolog 10.394
Ascl1achaete-scute complex homolog 1 (Drosophila)0.364
Ptpn11protein tyrosine phosphatase, non-receptor type 110.351
Pbx1pre B-cell leukemia transcription factor 10.321
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.317
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.313
Acvr1activin A receptor, type 10.312
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.302
Gscgoosecoid homeobox0.292
Notch1Notch gene homolog 1 (Drosophila)0.289
Smosmoothened homolog (Drosophila)0.281
Msx2homeobox, msh-like 20.277
Dlx5distal-less homeobox 50.277
Rspo2R-spondin 2 homolog (Xenopus laevis)0.272
Sox10SRY-box containing gene 100.267
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.244
Smad6MAD homolog 6 (Drosophila)0.241
Sox4SRY-box containing gene 40.240
Rb1retinoblastoma 10.239
Bmpr1abone morphogenetic protein receptor, type 1A0.239
Sall3sal-like 3 (Drosophila)0.231
Tgfb2transforming growth factor, beta 20.220
Lef1lymphoid enhancer binding factor 10.216
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.213
Insm1insulinoma-associated 10.198
Efnb2ephrin B20.184
Tsc2tuberous sclerosis 20.174
Dlx6distal-less homeobox 60.169
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.168
Prrx2paired related homeobox 20.156
Gli2GLI-Kruppel family member GLI20.154
Dll1delta-like 1 (Drosophila)0.141
Lhx3LIM homeobox protein 30.135
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.133
Ptenphosphatase and tensin homolog0.133
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.130
Col2a1collagen, type II, alpha 10.129
Rararetinoic acid receptor, alpha0.128
Hoxa2homeobox A20.128
Itgb1integrin beta 1 (fibronectin receptor beta)0.126
Sox1SRY-box containing gene 10.125
Sox11SRY-box containing gene 110.123
Gata4GATA binding protein 40.121
Olig2oligodendrocyte transcription factor 20.118
Chd7chromodomain helicase DNA binding protein 70.115
Cckbrcholecystokinin B receptor0.114
Trp63transformation related protein 630.108
Tbx1T-box 10.107
Emid2EMI domain containing 20.101
Psen1presenilin 10.101
Bmp7bone morphogenetic protein 70.101
Tbx3T-box 30.095
Lmx1bLIM homeobox transcription factor 1 beta0.093
Pou3f3POU domain, class 3, transcription factor 30.092
Rxraretinoid X receptor alpha0.088
Shesrc homology 2 domain-containing transforming protein E0.086
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.086
Foxg1forkhead box G10.086
Rarbretinoic acid receptor, beta0.084
Foxc2forkhead box C20.082
Msi1Musashi homolog 1(Drosophila)0.080
Gbx2gastrulation brain homeobox 20.078
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism