The network for 'regulation of carbohydrate biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of carbohydrate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.

NameDescriptionProbabilityFunc Analog Organism
INSRinsulin receptor0.959
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.896
MDM2Mdm2 p53 binding protein homolog (mouse)0.853
ESR1estrogen receptor 10.845
GRB10growth factor receptor-bound protein 100.607
PTPN1protein tyrosine phosphatase, non-receptor type 10.464
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.393
ARandrogen receptor0.381
PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.373
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.355
APPamyloid beta (A4) precursor protein0.316
SIRT1sirtuin 10.295
IGF1Rinsulin-like growth factor 1 receptor0.214
PRKAA1protein kinase, AMP-activated, alpha 1 catalytic subunit0.204
NUMBnumb homolog (Drosophila)0.191
FYNFYN oncogene related to SRC, FGR, YES0.177
EGFRepidermal growth factor receptor0.168
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.166
EP300E1A binding protein p3000.164
MAPTmicrotubule-associated protein tau0.131
RARAretinoic acid receptor, alpha0.127
IRS1insulin receptor substrate 10.127
SH2B1SH2B adaptor protein 10.114
GHRgrowth hormone receptor0.111
PPP4R2protein phosphatase 4, regulatory subunit 20.111
IRS2insulin receptor substrate 20.108
BCL3B-cell CLL/lymphoma 30.107
NCOR2nuclear receptor corepressor 20.098
RXRAretinoid X receptor, alpha0.098
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.094
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.086
HIP1huntingtin interacting protein 10.083
NCF2neutrophil cytosolic factor 20.078
SHC1SHC (Src homology 2 domain containing) transforming protein 10.077
TRRAPtransformation/transcription domain-associated protein0.076
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.076
NCOA1nuclear receptor coactivator 10.074
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.072
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.072
PPP1R2protein phosphatase 1, regulatory (inhibitor) subunit 20.072
NCF1neutrophil cytosolic factor 10.057
CREBBPCREB binding protein0.057
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.055
NOXA1NADPH oxidase activator 10.052
NCOA6nuclear receptor coactivator 60.051
PRKCAprotein kinase C, alpha0.051
KAT2BK(lysine) acetyltransferase 2B0.050
TADA3transcriptional adaptor 30.049
BCAR1breast cancer anti-estrogen resistance 10.049
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.047
DCTN1dynactin 10.046
DYRK1Bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B0.042
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.041
ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 10.040
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.039
THBS1thrombospondin 10.039
NRP1neuropilin 10.038
HTThuntingtin0.038
AKT1v-akt murine thymoma viral oncogene homolog 10.036
STAT5Bsignal transducer and activator of transcription 5B0.036
SORBS3sorbin and SH3 domain containing 30.035
PRKAG1protein kinase, AMP-activated, gamma 1 non-catalytic subunit0.033
CCDC101coiled-coil domain containing 1010.032
VEGFAvascular endothelial growth factor A0.031
NCOA3nuclear receptor coactivator 30.030
LZTS2leucine zipper, putative tumor suppressor 20.030
TADA2Atranscriptional adaptor 2A0.028
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.028
DCAF7DDB1 and CUL4 associated factor 70.028
PRKCBprotein kinase C, beta0.028
RAB5ARAB5A, member RAS oncogene family0.027
LRRK2leucine-rich repeat kinase 20.027
PRKCDprotein kinase C, delta0.027
SEMA6Asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.027
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.026
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.026
FHL2four and a half LIM domains 20.026
ITGB1BP3integrin beta 1 binding protein 30.025
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.024
PRKAG2protein kinase, AMP-activated, gamma 2 non-catalytic subunit0.024
SMAD3SMAD family member 30.024
ACACAacetyl-CoA carboxylase alpha0.024
FUNDC2FUN14 domain containing 20.023
TOM1L1target of myb1 (chicken)-like 10.023
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.022
DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 20.022
MATKmegakaryocyte-associated tyrosine kinase0.022
GSK3Bglycogen synthase kinase 3 beta0.021
PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.021
SNCAIPsynuclein, alpha interacting protein0.021
ENGendoglin0.020
ATXN3ataxin 30.019
EPS15epidermal growth factor receptor pathway substrate 150.019
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.019
PRKAA2protein kinase, AMP-activated, alpha 2 catalytic subunit0.019
FOXO3forkhead box O30.019
HNF4Ahepatocyte nuclear factor 4, alpha0.019
PGFplacental growth factor0.018
DYRK4dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 40.018
USP22ubiquitin specific peptidase 220.018
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
adipor2adiponectin receptor 20.094
ptprkprotein tyrosine phosphatase, receptor type, K0.091
cps1carbamoyl-phosphate synthase 1, mitochondrial0.090
LOC559201similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3)0.088
elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.076
acadlacyl-Coenzyme A dehydrogenase, long chain0.072
mtpmicrosomal triglyceride transfer protein0.071
LOC555482tachykinin receptor 3-like0.067
plxnb2aplexin b2a0.067
hlxb9lahomeo box HB9 like a0.063
fshbfollicle stimulating hormone, beta polypeptide0.063
si:dkey-228g21.4si:dkey-228g21.40.061
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.060
zgc:110105zgc:1101050.053
furinbfurin (paired basic amino acid cleaving enzyme) b0.048
myh11amyosin, heavy polypeptide 11, smooth muscle a0.043
ogt.2O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 20.041
mt2metallothionein 20.040
slc12a10.2solute carrier family 12 (sodium/potassium/chloride transporters), member 10.20.037
kiss2kisspeptin 20.034
zgc:56466zgc:564660.033
abcf2ATP-binding cassette, sub-family F (GCN20), member 20.033
st14asuppression of tumorigenicity 14 (colon carcinoma) a0.032
ptk2.1protein tyrosine kinase 2a0.032
per2period homolog 2 (Drosophila)0.031
jmjd2aljumonji domain containing 2A, like0.031
paqr8progestin and adipoQ receptor family member VIII0.031
vdravitamin D receptor a0.031
leprleptin receptor0.031
wwp1WW domain containing E3 ubiquitin protein ligase 10.030
igf1rainsulin-like growth factor 1a receptor0.029
lmnalamin A0.029
igf1rbinsulin-like growth factor 1b receptor0.028
zgc:158667zgc:1586670.027
tsc22d3TSC22 domain family, member 30.027
nktrnatural killer-tumor recognition sequence0.027
notch1bnotch homolog 1b0.027
igf2binsulin-like growth factor 2b0.027
clockclock0.027
ncoa2nuclear receptor coactivator 20.026
si:ch211-148j1.1si:ch211-148j1.10.026
appaamyloid beta (A4) precursor protein a0.025
shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.025
zgc:56306zgc:563060.025
pomcaproopiomelanocortin a0.025
rxrbbretinoid x receptor, beta b0.025
socs3asuppressor of cytokine signaling 3a0.024
rnasel1ribonuclease like 10.024
wu:fc54b10wu:fc54b100.023
pacsin3protein kinase C and casein kinase substrate in neurons 30.023
hoxc4ahomeo box C4a0.023
dnm2ldynamin2-like0.022
s1pr3sphingosine-1-phosphate receptor 30.022
mgea5meningioma expressed antigen 5 (hyaluronidase)0.022
cnihcornichon homolog (Drosophila)0.022
psen1presenilin 10.022
fnbp4formin binding protein 40.022
LOC569642hypothetical protein LOC5696420.022
LOC100537975thyroid receptor-interacting protein 11-like0.021
mbnl1muscleblind-like (Drosophila)0.021
cand1cullin-associated and neddylation-dissociated 10.021
rspo1R-spondin homolog (Xenopus laevis)0.021
gata4GATA-binding protein 40.021
pdia5protein disulfide isomerase family A, member 50.021
cry2acryptochrome 2a0.021
hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase0.020
igf2ainsulin-like growth factor 2a0.020
wu:fc48e01wu:fc48e010.020
gpt2lglutamic pyruvate transaminase (alanine aminotransferase) 2, like0.020
lhbluteinizing hormone, beta polypeptide0.020
junbjun B proto-oncogene0.020
zgc:113183zgc:1131830.020
plk3polo-like kinase 3 (Drosophila)0.020
ndrg1N-myc downstream regulated gene 10.020
terttelomerase reverse transcriptase0.020
vwfvon Willebrand factor0.020
im:7150937im:71509370.020
lamb2laminin, beta 2 (laminin S)0.020
eif4g2aeukaryotic translation initiation factor 4, gamma 2a0.019
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.019
hdac9bhistone deacetylase 9b0.019
selenbp1selenium binding protein 10.019
dsg2desmoglein 20.019
wsb1WD repeat and SOCS box-containing 10.019
wnt9awingless-type MMTV integration site family, member 9A0.019
ptprfprotein tyrosine phosphatase, receptor type, F0.019
arandrogen receptor0.019
stat3signal transduction and activation of transcription 30.019
cldn15aclaudin 15a0.019
hsd17b1hydroxysteroid (17-beta) dehydrogenase 10.019
aftphaaftiphilin a0.019
zgc:112986zgc:1129860.019
ripk2receptor-interacting serine-threonine kinase 20.019
cldn12claudin 120.019
ezh2enhancer of zeste homolog 2 (Drosophila)0.019
cyp1d1cytochrome P450, family 1, subfamily D, polypeptide 10.019
dnttdeoxynucleotidyltransferase, terminal0.019
sod1superoxide dismutase 1, soluble0.018
fabp10afatty acid binding protein 10a, liver basic0.018
add3aadducin 3 (gamma) a0.018
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Insrinsulin receptor1.000
Lepleptin0.998
Esr1estrogen receptor 1 (alpha)0.986
Prlrprolactin receptor0.953
Leprleptin receptor0.889
Arandrogen receptor0.841
Drd2dopamine receptor D20.810
Irs2insulin receptor substrate 20.792
LOC100048884novel member of the major urinary protein (Mup) gene family0.758
Clk4CDC like kinase 40.744
C1qccomplement component 1, q subcomponent, C chain0.694
Fshrfollicle stimulating hormone receptor0.653
Kiss1KiSS-1 metastasis-suppressor0.641
Nos1nitric oxide synthase 1, neuronal0.582
Clk1CDC-like kinase 10.572
Akt1thymoma viral proto-oncogene 10.548
Igf1rinsulin-like growth factor I receptor0.534
Ghrgrowth hormone receptor0.531
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.464
Ccnl2cyclin L20.464
Hnf4ahepatic nuclear factor 4, alpha0.442
Esr2estrogen receptor 2 (beta)0.423
Pax2paired box gene 20.403
Tcf7transcription factor 7, T-cell specific0.402
Mup19major urinary protein 190.395
Mup9major urinary protein 90.373
Mark4MAP/microtubule affinity-regulating kinase 40.344
Mup10major urinary protein 100.344
Pim1proviral integration site 10.343
Pax8paired box gene 80.340
SrcRous sarcoma oncogene0.332
Ppargperoxisome proliferator activated receptor gamma0.329
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.325
Stat5asignal transducer and activator of transcription 5A0.320
Cav1caveolin 1, caveolae protein0.303
Thrathyroid hormone receptor alpha0.301
Lhcgrluteinizing hormone/choriogonadotropin receptor0.298
Lipelipase, hormone sensitive0.293
Lhx3LIM homeobox protein 30.291
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.289
Bglapbone gamma carboxyglutamate protein0.274
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.267
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.257
Nos3nitric oxide synthase 3, endothelial cell0.250
Ptenphosphatase and tensin homolog0.241
Sim1single-minded homolog 1 (Drosophila)0.235
Cdkn1bcyclin-dependent kinase inhibitor 1B0.223
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.220
D4Wsu53eDNA segment, Chr 4, Wayne State University 53, expressed0.217
Mup3major urinary protein 30.211
Hbb-b1hemoglobin, beta adult major chain0.210
Socs1suppressor of cytokine signaling 10.201
Grb10growth factor receptor bound protein 100.195
Pim3proviral integration site 30.191
Igf1insulin-like growth factor 10.191
Spry4sprouty homolog 4 (Drosophila)0.180
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.176
C1qacomplement component 1, q subcomponent, alpha polypeptide0.170
Rxrgretinoid X receptor gamma0.167
Mup4major urinary protein 40.166
Mup8major urinary protein 80.166
Fgafibrinogen alpha chain0.162
Mup1major urinary protein 10.161
Pnpla2patatin-like phospholipase domain containing 20.159
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.158
Mup7major urinary protein 70.156
F9coagulation factor IX0.153
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.150
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.148
Npc1Niemann Pick type C10.146
Cps1carbamoyl-phosphate synthetase 10.146
Mup14major urinary protein 140.141
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.141
Nr0b1nuclear receptor subfamily 0, group B, member 10.141
F2coagulation factor II0.137
Dmgdhdimethylglycine dehydrogenase precursor0.137
Amhr2anti-Mullerian hormone type 2 receptor0.136
Nr1h4nuclear receptor subfamily 1, group H, member 40.135
Mup13major urinary protein 130.134
VgfVGF nerve growth factor inducible0.130
Onecut1one cut domain, family member 10.126
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.125
Egfrepidermal growth factor receptor0.125
Mup5major urinary protein 50.124
Mup17major urinary protein 170.124
Csf1rcolony stimulating factor 1 receptor0.124
Pim2proviral integration site 20.123
Ulk1Unc-51 like kinase 1 (C. elegans)0.122
Csf1colony stimulating factor 1 (macrophage)0.117
Cyp2c39cytochrome P450, family 2, subfamily c, polypeptide 390.116
C1qbcomplement component 1, q subcomponent, beta polypeptide0.116
Apoa1apolipoprotein A-I0.111
Mup12major urinary protein 120.110
Mup11major urinary protein 110.110
Serpina3cserine (or cysteine) peptidase inhibitor, clade A, member 3C0.109
Lef1lymphoid enhancer binding factor 10.108
Ren1renin 1 structural0.107
Bcl2B-cell leukemia/lymphoma 20.107
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.105
S100a5S100 calcium binding protein A50.103
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Serinc1serine incorporator 10.012
Snrpbsmall nuclear ribonucleoprotein polypeptides B and B10.010
Eef2eukaryotic translation elongation factor 20.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RHO1Rho1p0.603
RMD5Rmd5p0.597
GSY2Gsy2p0.578
FYV10Fyv10p0.553
GID7Gid7p0.522
VID30Vid30p0.501
GLC7Glc7p0.371
GSY1Gsy1p0.355
GIP2Gip2p0.312
GID8Gid8p0.304
BEM4Bem4p0.259
RDI1Rdi1p0.222
MOH1Moh1p0.219
SLG1Slg1p0.211
BEM2Bem2p0.202
GLG2Glg2p0.147
PIG2Pig2p0.143
VID24Vid24p0.132
MMR1Mmr1p0.104
SNF1Snf1p0.095
ANP1Anp1p0.093
SAK1Sak1p0.091
CAK1Cak1p0.090
HOC1Hoc1p0.083
YAP6Yap6p0.081
UGP1Ugp1p0.077
VID28Vid28p0.075
CKB2Ckb2p0.074
RDS2Rds2p0.064
GPH1Gph1p0.063
MTL1Mtl1p0.059
MKK2Mkk2p0.055
UME1Ume1p0.054
PKH2Pkh2p0.049
YNL194Chypothetical protein0.048
AZF1Azf1p0.048
MKK1Mkk1p0.047
HXK1Hxk1p0.046
LEE1Lee1p0.046
SPR6Spr6p0.044
MSS4Mss4p0.044
PCL2Pcl2p0.042
YJR115Whypothetical protein0.039
BPH1Bph1p0.038
CLB6Clb6p0.038
GYL1Gyl1p0.038
BDH1Bdh1p0.037
CTF13Ctf13p0.037
GLG1Glg1p0.037
ROM2Rom2p0.036
SAT4Sat4p0.036
YDR286Chypothetical protein0.035
MBR1Mbr1p0.035
YDR186Chypothetical protein0.035
FYV8Fyv8p0.034
HDA1Hda1p0.034
ROM1Rom1p0.033
COA4Coa4p0.032
SKT5Skt5p0.032
YMR210Whypothetical protein0.031
THG1Thg1p0.030
CIK1Cik1p0.030
ERT1Ert1p0.029
GAC1Gac1p0.029
GIC1Gic1p0.029
UBP7Ubp7p0.028
SSH4Ssh4p0.028
SDS3Sds3p0.028
YKR075Chypothetical protein0.028
YGK3Ygk3p0.028
ATG20Atg20p0.028
EMI2Emi2p0.028
GTS1Gts1p0.028
PCL9Pcl9p0.028
YNR014Whypothetical protein0.027
CBK1Cbk1p0.027
NGR1Ngr1p0.027
YKL187Chypothetical protein0.027
BRE5Bre5p0.026
SPO1Spo1p0.026
YLR264C-Ahypothetical protein0.026
ADR1Adr1p0.026
OCH1Och1p0.026
YHR022Chypothetical protein0.026
PPE1Ppe1p0.026
GBP2Gbp2p0.025
YCR007Chypothetical protein0.025
BRN1Brn1p0.025
GPM2Gpm2p0.025
COX23Cox23p0.025
CUE2Cue2p0.025
SOK1Sok1p0.025
AST2Ast2p0.025
DBF2Dbf2p0.025
FAA1Faa1p0.024
AVT7Avt7p0.024
SOL1Sol1p0.024
AIM11Aim11p0.024
TAO3Tao3p0.024
SRD1Srd1p0.023