The network for 'response to nerve growth factor' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to nerve growth factor

A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.

NameDescriptionProbabilityFunc Analog Organism
GGA2golgi-associated, gamma adaptin ear containing, ARF binding protein 20.881
GGA1golgi-associated, gamma adaptin ear containing, ARF binding protein 10.594
RAPGEF2Rap guanine nucleotide exchange factor (GEF) 20.497
PLAUplasminogen activator, urokinase0.381
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.348
SORT1sortilin 10.208
PLCG1phospholipase C, gamma 10.200
RB1retinoblastoma 10.199
WASLWiskott-Aldrich syndrome-like0.187
SYNRGsynergin, gamma0.168
CDK2cyclin-dependent kinase 20.167
IGF2Rinsulin-like growth factor 2 receptor0.144
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.127
ADRB1adrenergic, beta-1-, receptor0.118
UHRF1ubiquitin-like with PHD and ring finger domains 10.093
NTRK1neurotrophic tyrosine kinase, receptor, type 10.090
PSEN2presenilin 2 (Alzheimer disease 4)0.085
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.079
NGFRnerve growth factor receptor0.075
ABI1abl-interactor 10.065
BCAR1breast cancer anti-estrogen resistance 10.056
TEX11testis expressed 110.042
SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome)0.042
SORL1sortilin-related receptor, L(DLR class) A repeats containing0.042
NGFnerve growth factor (beta polypeptide)0.038
TFDP1transcription factor Dp-10.038
FGFR1fibroblast growth factor receptor 10.021
RABEP1rabaptin, RAB GTPase binding effector protein 10.021
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.019
LATlinker for activation of T cells0.018
PLATplasminogen activator, tissue0.017
ATP2B2ATPase, Ca++ transporting, plasma membrane 20.016
TNFRSF12Atumor necrosis factor receptor superfamily, member 12A0.015
GPRASP2G protein-coupled receptor associated sorting protein 20.014
CCDC85Acoiled-coil domain containing 85A0.013
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.013
ATP8ATP synthase F0 subunit 80.012
RAP1ARAP1A, member of RAS oncogene family0.011
E2F2E2F transcription factor 20.011
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.011
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.011
MAP4K1mitogen-activated protein kinase kinase kinase kinase 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.953
Bdnfbrain derived neurotrophic factor0.865
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.841
Ntf3neurotrophin 30.772
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.600
Ntf5neurotrophin 50.507
Vti1avesicle transport through interaction with t-SNAREs homolog 1A (yeast)0.491
Nrg1neuregulin 10.383
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.345
Galgalanin0.133
Dstdystonin0.123
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.113
Tbx10T-box 100.112
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.110
Cacng2calcium channel, voltage-dependent, gamma subunit 20.102
Phox2apaired-like homeobox 2a0.072
Grxcr1glutaredoxin, cysteine rich 10.072
Hoxa1homeobox A10.060
Mbmyoglobin0.045
Nraddneurotrophin receptor associated death domain0.044
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.040
Grb2growth factor receptor bound protein 20.039
Hey2hairy/enhancer-of-split related with YRPW motif 20.037
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.036
Adora3adenosine A3 receptor0.035
Chrdchordin0.034
Tbx15T-box 150.033
Kcnj10potassium inwardly-rectifying channel, subfamily J, member 100.028
Shkbp1Sh3kbp1 binding protein 10.027
Eya1eyes absent 1 homolog (Drosophila)0.027
Fliiflightless I homolog (Drosophila)0.027
Arrb2arrestin, beta 20.026
Dbnldrebrin-like0.025
Hbegfheparin-binding EGF-like growth factor0.025
Ikbkapinhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein0.025
Dok7docking protein 70.024
Capzbcapping protein (actin filament) muscle Z-line, beta0.024
Shhsonic hedgehog0.022
Hand2heart and neural crest derivatives expressed transcript 20.020
Nos1nitric oxide synthase 1, neuronal0.020
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.020
Fgf9fibroblast growth factor 90.019
Adrbk1adrenergic receptor kinase, beta 10.019
Wnt5awingless-related MMTV integration site 5A0.018
Retret proto-oncogene0.018
Emx1empty spiracles homolog 1 (Drosophila)0.017
Etv1ets variant gene 10.017
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.017
Cybacytochrome b-245, alpha polypeptide0.016
Pou4f3POU domain, class 4, transcription factor 30.015
Fgfr3fibroblast growth factor receptor 30.015
Maffv-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)0.015
Rps6ka1ribosomal protein S6 kinase polypeptide 10.015
Zeb1zinc finger E-box binding homeobox 10.015
Hdac1histone deacetylase 10.015
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.014
Cxcr7chemokine (C-X-C motif) receptor 70.014
Cskc-src tyrosine kinase0.014
Foxg1forkhead box G10.014
Dock1dedicator of cytokinesis 10.014
Necap2NECAP endocytosis associated 20.013
Rfc2replication factor C (activator 1) 20.013
Sh3bgrl3SH3 domain binding glutamic acid-rich protein-like 30.013
Sos1son of sevenless homolog 1 (Drosophila)0.013
Isl1ISL1 transcription factor, LIM/homeodomain0.013
Sox11SRY-box containing gene 110.013
Cfl1cofilin 1, non-muscle0.013
Twist2twist homolog 2 (Drosophila)0.013
Cyr61cysteine rich protein 610.013
Fermt3fermitin family homolog 3 (Drosophila)0.013
Msx2homeobox, msh-like 20.013
Ctszcathepsin Z0.013
Nr3c1nuclear receptor subfamily 3, group C, member 10.013
Fgf8fibroblast growth factor 80.012
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.012
Cotl1coactosin-like 1 (Dictyostelium)0.012
Angptl1angiopoietin-like 10.012
Myom2myomesin 20.012
Efna1ephrin A10.012
Stxbp2syntaxin binding protein 20.012
Htra3HtrA serine peptidase 30.012
Ap2s1adaptor-related protein complex 2, sigma 1 subunit0.012
Entpd2ectonucleoside triphosphate diphosphohydrolase 20.011
Vti1bvesicle transport through interaction with t-SNAREs 1B homolog0.011
Gnb2guanine nucleotide binding protein (G protein), beta 20.011
Map3k6mitogen-activated protein kinase kinase kinase 60.011
Egr3early growth response 30.010
Pitpnm1phosphatidylinositol transfer protein, membrane-associated 10.010
Trim28tripartite motif-containing 280.010
Cxcl14chemokine (C-X-C motif) ligand 140.010
P2ry2purinergic receptor P2Y, G-protein coupled 20.010
Cdc42se1CDC42 small effector 10.010
Shisa5shisa homolog 5 (Xenopus laevis)0.010
Amdhd2amidohydrolase domain containing 20.010
Timp4tissue inhibitor of metalloproteinase 40.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism