The network for 'erythrocyte homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

erythrocyte homeostasis

Any process of regulating the production and elimination of erythrocytes within an organism.

NameDescriptionProbabilityFunc Analog Organism
TAL1T-cell acute lymphocytic leukemia 11.000
CREBBPCREB binding protein0.999
SMAD2SMAD family member 20.979
JUNjun proto-oncogene0.960
RUNX1runt-related transcription factor 10.939
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.904
CREB1cAMP responsive element binding protein 10.827
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.807
EP300E1A binding protein p3000.807
KAT2BK(lysine) acetyltransferase 2B0.798
NCOA6nuclear receptor coactivator 60.769
GATA1GATA binding protein 1 (globin transcription factor 1)0.757
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.667
RPS16ribosomal protein S160.637
HOXB5homeobox B50.624
KLF6Kruppel-like factor 60.612
DDIT3DNA-damage-inducible transcript 30.593
SMAD3SMAD family member 30.489
RPS10ribosomal protein S100.480
NFE2L2nuclear factor (erythroid-derived 2)-like 20.453
INSRinsulin receptor0.450
RPS2ribosomal protein S20.447
NCOA1nuclear receptor coactivator 10.446
RPS19ribosomal protein S190.440
GHRgrowth hormone receptor0.433
CASP3caspase 3, apoptosis-related cysteine peptidase0.432
DUSP1dual specificity phosphatase 10.425
TCF12transcription factor 120.406
SMAD7SMAD family member 70.393
NCOA3nuclear receptor coactivator 30.380
ATF3activating transcription factor 30.349
TP53tumor protein p530.337
CDK2cyclin-dependent kinase 20.298
GATA2GATA binding protein 20.275
HOXA5homeobox A50.273
NCOR2nuclear receptor corepressor 20.272
ANK1ankyrin 1, erythrocytic0.258
CASP8caspase 8, apoptosis-related cysteine peptidase0.258
NCOA2nuclear receptor coactivator 20.246
HOXA10homeobox A100.242
PTPN1protein tyrosine phosphatase, non-receptor type 10.237
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.231
APAF1apoptotic peptidase activating factor 10.229
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.224
SLC4A1solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)0.222
CCND1cyclin D10.220
KLF4Kruppel-like factor 4 (gut)0.219
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.218
FOSFBJ murine osteosarcoma viral oncogene homolog0.214
RHAGRh-associated glycoprotein0.210
BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 10.206
SIN3ASIN3 homolog A, transcription regulator (yeast)0.206
RPL27ribosomal protein L270.197
FKBP1AFK506 binding protein 1A, 12kDa0.186
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.185
XIAPX-linked inhibitor of apoptosis0.164
RPLP2ribosomal protein, large, P20.161
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.160
CASP10caspase 10, apoptosis-related cysteine peptidase0.159
RPS15ribosomal protein S150.149
MYOD1myogenic differentiation 10.148
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.146
SP100SP100 nuclear antigen0.142
SPTBspectrin, beta, erythrocytic0.141
NFIL3nuclear factor, interleukin 3 regulated0.140
BMPR1Abone morphogenetic protein receptor, type IA0.137
ARandrogen receptor0.133
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.130
JAK2Janus kinase 20.129
ARID4BAT rich interactive domain 4B (RBP1-like)0.128
SP1Sp1 transcription factor0.127
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.124
RPS27ribosomal protein S270.124
SUMO3SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)0.123
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.122
PPP1R15Aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.122
MAFBv-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)0.115
SIRT1sirtuin 10.115
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.115
SMAD4SMAD family member 40.110
RPS6ribosomal protein S60.109
SETD8SET domain containing (lysine methyltransferase) 80.109
RBPMSRNA binding protein with multiple splicing0.105
GAS6growth arrest-specific 60.104
GATA4GATA binding protein 40.101
RPS5ribosomal protein S50.100
RPS11ribosomal protein S110.099
SH2D4ASH2 domain containing 4A0.098
RPL36ribosomal protein L360.093
HBG2hemoglobin, gamma G0.092
MDM2Mdm2 p53 binding protein homolog (mouse)0.092
RPS7ribosomal protein S70.092
RPS23ribosomal protein S230.085
CFLARCASP8 and FADD-like apoptosis regulator0.079
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.077
RPL23Aribosomal protein L23a0.076
HIPK2homeodomain interacting protein kinase 20.075
EGLN1egl nine homolog 1 (C. elegans)0.074
CRADDCASP2 and RIPK1 domain containing adaptor with death domain0.073
U2AF1U2 small nuclear RNA auxiliary factor 10.073
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tfr1atransferrin receptor 1a0.996
alas2aminolevulinate, delta-, synthetase 20.995
epb41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)0.995
lmo2LIM domain only 2 (rhombotin-like 1)0.994
pax2apaired box gene 2a0.990
tal1T-cell acute lymphocytic leukemia 10.983
slc4a1asolute carrier family 4, anion exchanger, member 1a0.982
hbae3hemoglobin alpha embryonic-30.967
pitx2paired-like homeodomain transcription factor 20.965
klf4Kruppel-like factor 40.962
hbbe1.1hemoglobin beta embryonic-1.10.960
hbae1hemoglobin alpha embryonic-10.951
LOC566708FL cytokine receptor-like0.949
hbbe3hemoglobin beta embryonic-30.838
plcg1phospholipase C, gamma 10.810
gfi1.1growth factor independent 1.10.794
gata1aGATA binding protein 1a0.780
cpoxcoproporphyrinogen oxidase0.772
uroduroporphyrinogen decarboxylase0.768
hbbe2hemoglobin beta embryonic-20.744
cahzcarbonic anhydrase0.711
hdrhematopoietic death receptor0.684
gata6GATA-binding protein 60.650
znfl2azinc finger-like gene 2a0.624
hand2heart and neural crest derivatives expressed transcript 20.594
spns2spinster homolog 2 (Drosophila)0.573
ikzf1IKAROS family zinc finger 1 (Ikaros)0.549
rpl11ribosomal protein L110.537
eporerythropoietin receptor0.536
drldraculin0.516
tspotranslocator protein0.513
tbx5aT-box 5a0.483
trim33tripartite motif-containing 330.483
gata5GATA-binding protein 50.435
klfdKruppel-like factor d0.428
hbaa1hemoglobin alpha adult-10.412
rpl38ribosomal protein L380.387
gapdhglyceraldehyde-3-phosphate dehydrogenase0.366
si:dkeyp-66d7.2si:dkeyp-66d7.20.354
rhagRhesus blood group-associated glycoprotein0.322
hoxd4ahomeo box D4a0.309
isl2aislet2a0.304
acvr2bactivin receptor IIb0.303
hoxb5bhomeo box B5b0.297
eomesaeomesodermin homolog a0.295
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.288
cx30.3connexin 30.30.276
rpl36aribosomal protein L36A0.250
cebp1CCAAT/enhancer binding protein (C/EBP) 10.246
mll4bmyeloid/lymphoid or mixed-lineage leukemia 4b0.228
cfl2lcofilin 2, like0.227
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.226
runx1runt-related transcription factor 10.221
sox7SRY-box containing gene 70.218
tbx2bT-box 2b0.216
trpv6transient receptor potential cation channel, subfamily V, member 60.214
myl7myosin, light polypeptide 7, regulatory0.213
fechferrochelatase0.207
kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.202
sptbspectrin, beta, erythrocytic0.201
tbx24T-box 240.197
spawsouthpaw0.196
chukconserved helix-loop-helix ubiquitous kinase0.189
rxrbaretinoid x receptor, beta a0.180
snx5sorting nexin 50.179
blvrbbiliverdin reductase B (flavin reductase (NADPH))0.175
fgf8afibroblast growth factor 8 a0.172
pdcd2programmed cell death 20.169
f2rcoagulation factor II (thrombin) receptor0.169
nt5c2l15'-nucleotidase, cytosolic II, like 10.169
atoh1aatonal homolog 1a0.168
setd8aSET domain containing (lysine methyltransferase) 8a0.162
vegfaavascular endothelial growth factor Aa0.160
hmbsbhydroxymethylbilane synthase, b0.157
lft2lefty20.153
rps19ribosomal protein S190.149
epas1bendothelial PAS domain protein 1b0.146
rps18ribosomal protein S180.145
LOC100151531zinc finger protein Gfi-1b-like0.134
aco1aconitase 1, soluble0.133
dhrs3adehydrogenase/reductase (SDR family) member 3a0.132
nkx2.5NK2 transcription factor related 50.131
hoxc4ahomeo box C4a0.131
ptf1apancreas specific transcription factor, 1a0.131
tfebtranscription factor EB0.129
rpl23aribosomal protein L23a0.127
zgc:77235zgc:772350.126
hoxb6ahomeo box B6a0.126
fli1afriend leukemia integration 1a0.125
si:dkey-181m9.9si:dkey-181m9.90.121
bcl2l10BCL2-like 10 (apoptosis facilitator)0.118
rpl23ribosomal protein L230.118
matr3lmatrin 3-like0.118
sema3aasemaphorin 3aa0.118
slc11a2solute carrier family 11 (proton-coupled divalent metal ion transporters), member 20.117
tmem14ctransmembrane protein 14C0.117
hnf1baHNF1 homeobox Ba0.116
atoh1batonal homolog 1b0.115
ttnatitin a0.115
zgc:110712zgc:1107120.114
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
LOC100134871beta globin minor gene0.186
Alas2aminolevulinate, delta-, synthase 20.064
LOC689064beta-globin0.054
LOC287167globin, alpha0.052
Rap1bRAP1B, member of RAS oncogene family0.042
Jak1Janus kinase 10.035
Mylk2myosin light chain kinase 20.027
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.026
Adam17ADAM metallopeptidase domain 170.024
Elk3ELK3, ETS-domain protein0.023
Sp1Sp1 transcription factor0.022
Ptprcprotein tyrosine phosphatase, receptor type, C0.022
Smc4structural maintenance of chromosomes 40.022
Rpl34ribosomal protein L340.022
Slc4a1solute carrier family 4 (anion exchanger), member 10.021
Dok1docking protein 10.021
Cfpcomplement factor properdin0.021
Stk3serine/threonine kinase 3 (STE20 homolog, yeast)0.020
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.020
Hba-a2hemoglobin alpha, adult chain 20.020
Smad2SMAD family member 20.019
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.019
Jak2Janus kinase 20.018
Xrn25'-3' exoribonuclease 20.018
N4bp2l2NEDD4 binding protein 2-like 20.018
Casp3caspase 30.017
Ptpn12protein tyrosine phosphatase, non-receptor type 120.017
UgdhUDP-glucose dehydrogenase0.017
Ireb2iron responsive element binding protein 20.017
Slc25a24solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 240.017
Cdc25bcell division cycle 25 homolog B (S. pombe)0.016
Insrinsulin receptor0.016
Man2a1mannosidase, alpha, class 2A, member 10.016
Rab5bRAB5B, member RAS oncogene family0.016
Laptm5lysosomal protein transmembrane 50.016
Baz1abromodomain adjacent to zinc finger domain, 1A0.016
Smad1SMAD family member 10.016
Flt1FMS-related tyrosine kinase 10.016
Rararetinoic acid receptor, alpha0.016
Slc5a3solute carrier family 5 (sodium/myo-inositol cotransporter), member 30.016
Lcp2lymphocyte cytosolic protein 20.015
Lbrlamin B receptor0.015
Rassf5Ras association (RalGDS/AF-6) domain family member 50.015
Actc1actin, alpha, cardiac muscle 10.015
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.015
Chd1chromodomain helicase DNA binding protein 10.015
Sppl2asignal peptide peptidase-like 2A0.015
H3f3bH3 histone, family 3B0.015
Pls3plastin 3 (T-isoform)0.015
Gltscr2glioma tumor suppressor candidate region gene 20.015
Gpr116G protein-coupled receptor 1160.015
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.015
UgcgUDP-glucose ceramide glucosyltransferase0.015
Sash3SAM and SH3 domain containing 30.015
Rab3il1RAB3A interacting protein (rabin3)-like 10.014
Slasrc-like adaptor0.014
Arntaryl hydrocarbon receptor nuclear translocator0.014
Atf1activating transcription factor 10.014
Lcp1lymphocyte cytosolic protein 10.014
Usp3ubiquitin specific peptidase 30.014
Marcksmyristoylated alanine rich protein kinase C substrate0.014
Vegfavascular endothelial growth factor A0.014
Picalmphosphatidylinositol binding clathrin assembly protein0.014
Vav1vav 1 guanine nucleotide exchange factor0.014
Sh2d3cSH2 domain containing 3C0.014
Hbb-b1hemoglobin, beta adult major chain0.014
Bmp6bone morphogenetic protein 60.014
TekTEK tyrosine kinase, endothelial0.014
Il13ra1interleukin 13 receptor, alpha 10.013
Pde4bphosphodiesterase 4B, cAMP specific0.013
Elf1E74-like factor 10.013
Dusp1dual specificity phosphatase 10.013
Ppp2r2dprotein phosphatase 2, regulatory subunit B, delta isoform0.013
Nlnneurolysin (metallopeptidase M3 family)0.013
Myo1bmyosin Ib0.013
Bmp7bone morphogenetic protein 70.013
Nab1Ngfi-A binding protein 10.013
Gja5gap junction protein, alpha 50.013
Apbb1ipamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein0.013
Setd7SET domain containing (lysine methyltransferase) 70.013
Arpc5actin related protein 2/3 complex, subunit 50.013
Plxnd1plexin D10.013
Pgm2phosphoglucomutase 20.013
G3bp2GTPase activating protein (SH3 domain) binding protein 20.013
Dusp7dual specificity phosphatase 70.013
Il1r1interleukin 1 receptor, type I0.013
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.013
Egfrepidermal growth factor receptor0.013
Map4k1mitogen activated protein kinase kinase kinase kinase 10.013
Unc119bunc-119 homolog B (C. elegans)0.013
MdficMyoD family inhibitor domain containing0.013
Dpy19l1dpy-19-like 1 (C. elegans)0.013
Mapre1microtubule-associated protein, RP/EB family, member 10.013
Acvr1activin A receptor, type I0.012
PawrPRKC, apoptosis, WT1, regulator0.012
Lrrfip1leucine rich repeat (in FLII) interacting protein 10.012
Dusp18dual specificity phosphatase 180.012
Sdc3syndecan 30.012
Tgfbr3transforming growth factor, beta receptor III0.012
Cald1caldesmon 10.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism