The network for 'receptor metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

receptor metabolic process

The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.

NameDescriptionProbabilityFunc Analog Organism
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.998
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.871
TEKTEK tyrosine kinase, endothelial0.785
ENGendoglin0.774
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.772
PSEN1presenilin 10.713
CCR5chemokine (C-C motif) receptor 50.692
ZFYVE9zinc finger, FYVE domain containing 90.618
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.605
ADRB1adrenergic, beta-1-, receptor0.578
SMURF2SMAD specific E3 ubiquitin protein ligase 20.550
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.517
STAM2signal transducing adaptor molecule (SH3 domain and ITAM motif) 20.504
HOXB5homeobox B50.503
APPL2adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 20.493
RARAretinoic acid receptor, alpha0.477
THBS1thrombospondin 10.475
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.446
EEA1early endosome antigen 10.445
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.431
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.429
CXCL9chemokine (C-X-C motif) ligand 90.384
DNM1dynamin 10.381
IL8interleukin 80.373
CXCL2chemokine (C-X-C motif) ligand 20.355
LRP6low density lipoprotein receptor-related protein 60.347
DNM2dynamin 20.335
PTPRBprotein tyrosine phosphatase, receptor type, B0.322
CXCL3chemokine (C-X-C motif) ligand 30.320
SMURF1SMAD specific E3 ubiquitin protein ligase 10.302
C1QAcomplement component 1, q subcomponent, A chain0.299
FN1fibronectin 10.299
ARFGEF2ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)0.297
ARRB2arrestin, beta 20.292
ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)0.287
SMAD4SMAD family member 40.286
ITKIL2-inducible T-cell kinase0.285
ARRB1arrestin, beta 10.276
TNFAIP3tumor necrosis factor, alpha-induced protein 30.265
CALCRLcalcitonin receptor-like0.260
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.258
SH3GL3SH3-domain GRB2-like 30.244
CXCL10chemokine (C-X-C motif) ligand 100.240
FGAfibrinogen alpha chain0.237
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.236
CXCL11chemokine (C-X-C motif) ligand 110.235
NCOR2nuclear receptor corepressor 20.233
RXRAretinoid X receptor, alpha0.215
PICALMphosphatidylinositol binding clathrin assembly protein0.210
PTPN1protein tyrosine phosphatase, non-receptor type 10.202
HDAC6histone deacetylase 60.195
CXCL5chemokine (C-X-C motif) ligand 50.195
NRP1neuropilin 10.191
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.191
ITGB4integrin, beta 40.182
CCL2chemokine (C-C motif) ligand 20.181
CCR2chemokine (C-C motif) receptor 20.180
PTPN23protein tyrosine phosphatase, non-receptor type 230.178
LDLRlow density lipoprotein receptor0.176
BBS10Bardet-Biedl syndrome 100.170
IFNGinterferon, gamma0.169
STX4syntaxin 40.167
HOXA5homeobox A50.167
IL10RAinterleukin 10 receptor, alpha0.164
TLN1talin 10.164
HPhaptoglobin0.161
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.160
CCL5chemokine (C-C motif) ligand 50.159
IL6interleukin 6 (interferon, beta 2)0.159
ADRBK1adrenergic, beta, receptor kinase 10.156
HOXA10homeobox A100.155
NEDD4neural precursor cell expressed, developmentally down-regulated 40.154
SH3GL2SH3-domain GRB2-like 20.148
PDIA3protein disulfide isomerase family A, member 30.142
EPAS1endothelial PAS domain protein 10.141
SNAP23synaptosomal-associated protein, 23kDa0.137
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.136
AMPHamphiphysin0.129
A2Malpha-2-macroglobulin0.128
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.125
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.122
CD28CD28 molecule0.122
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.121
ATXN3ataxin 30.118
CCL20chemokine (C-C motif) ligand 200.118
GTF2H1general transcription factor IIH, polypeptide 1, 62kDa0.118
CXCR2chemokine (C-X-C motif) receptor 20.116
CCL8chemokine (C-C motif) ligand 80.116
APOC1apolipoprotein C-I0.115
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.115
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.114
DEDDdeath effector domain containing0.113
SYNMsynemin, intermediate filament protein0.112
RNF11ring finger protein 110.111
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.110
HOXB7homeobox B70.109
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.109
NCOA6nuclear receptor coactivator 60.109
SNX9sorting nexin 90.108
IL22RA1interleukin 22 receptor, alpha 10.107
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ace-2Protein ACE-20.327
ace-4Protein ACE-40.229
F41E6.9Protein F41E6.90.116
ace-1Protein ACE-10.104
ace-3Protein ACE-30.076
rpn-6.1Protein RPN-6.10.057
daf-11Protein DAF-110.050
dnc-2Protein DNC-20.041
vps-37Protein VPS-370.041
CELE_Y57G11C.3Protein Y57G11C.30.036
C31E10.5Protein C31E10.50.034
twk-18Protein TWK-180.032
tag-353Protein TAG-3530.027
cka-1Protein CKA-10.026
snap-1Protein SNAP-10.025
F21C10.7Protein F21C10.70.024
gpb-1Protein GPB-10.023
ajm-1Protein AJM-10.019
trim-9Protein TRIM-90.019
pkg-1Protein PKG-10.018
egl-44Protein EGL-440.017
T22C1.6Protein T22C1.60.017
CELE_T03F6.3Protein T03F6.30.016
lmn-1Protein LMN-10.015
lgc-34Protein LGC-340.012
T27F6.7Protein T27F6.70.012
ast-1Protein AST-10.012
mvb-12Protein MVB-120.012
rad-23Protein RAD-230.012
F09A5.4Protein F09A5.40.012
CELE_C25A1.5Protein C25A1.50.011
K02A6.2Protein K02A6.20.011
dnj-16Protein DNJ-160.011
pqn-89Protein PQN-890.011
C27C12.1Protein C27C12.10.011
ehs-1Protein EHS-10.010
lst-4Protein LST-40.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
gria2aglutamate receptor, ionotropic, AMPA 2a0.156
mibmind bomb0.087
bc2putative breast adenocarcinoma marker0.080
dccdeleted in colorectal carcinoma0.063
dzip1DAZ interacting protein 10.055
gria2bglutamate receptor, ionotropic, AMPA 2b0.040
gria4aglutamate receptor, ionotropic, AMPA 4a0.034
chmp4bchromatin modifying protein 4B0.026
epas1bendothelial PAS domain protein 1b0.026
prkcqprotein kinase C, theta0.022
LOC100000687signal peptide, CUB and EGF-like domain-containing protein 3-like0.022
amotl2aangiomotin like 2a0.020
dlg2discs, large (Drosophila) homolog 20.017
aldocbaldolase C, fructose-bisphosphate, b0.016
dlg1discs, large (Drosophila) homolog 10.016
grin1aglutamate receptor, ionotropic, N-methyl D-aspartate 1a0.015
hoxa13ahomeo box A13a0.014
zgc:77849zgc:778490.014
pi4kbphosphatidylinositol 4-kinase, catalytic, beta0.014
trpc5transient receptor potential cation channel, subfamily C, member 50.013
igfbp1ainsulin-like growth factor binding protein 1a0.013
ghrbgrowth hormone receptor b0.013
rcv1recoverin0.012
ssbp3bsingle stranded DNA binding protein 3b0.012
ube2d1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.011
klf2bKruppel-like factor 2b0.011
zgc:103663zgc:1036630.011
cacna1abcalcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b0.010
cxcr4bchemokine (C-X-C motif), receptor 4b0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Grip1glutamate receptor interacting protein 10.800
Baiap2BAI1-associated protein 20.431
Fgf7fibroblast growth factor 70.329
Gabrr1gamma-aminobutyric acid (GABA) receptor, rho 10.300
Gria3glutamate receptor, ionotrophic, AMPA 30.255
Cd80Cd80 molecule0.232
Hpcal1hippocalcin-like 10.203
Sec23aSec23 homolog A (S. cerevisiae)0.152
Gria2glutamate receptor, ionotropic, AMPA 20.147
Mmp13matrix metallopeptidase 130.146
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.145
Trhrthyrotropin releasing hormone receptor0.136
Apbb3amyloid beta (A4) precursor protein-binding, family B, member 30.133
Atp6v1b2ATPase, H transporting, lysosomal V1 subunit B20.125
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.123
DbpD site of albumin promoter (albumin D-box) binding protein0.118
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.114
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.106
Amphamphiphysin0.102
Accn3amiloride-sensitive cation channel 30.098
Dgkzdiacylglycerol kinase zeta0.098
Syngap1synaptic Ras GTPase activating protein 1 homolog (rat)0.097
Impg2interphotoreceptor matrix proteoglycan 20.095
Syt6synaptotagmin VI0.089
Ptmsparathymosin0.088
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.082
Cma1chymase 1, mast cell0.082
Grinaglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.077
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.075
Cacnb4calcium channel, voltage-dependent, beta 4 subunit0.074
Kcna6potassium voltage gated channel, shaker related subfamily, member 60.071
Map2microtubule-associated protein 20.071
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.069
Kcnc2potassium voltage gated channel, Shaw-related subfamily, member 20.065
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.064
Akr1c14aldo-keto reductase family 1, member C140.062
Dlg4discs, large homolog 4 (Drosophila)0.062
Pik3r2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.060
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.060
Magmyelin-associated glycoprotein0.056
Shank1SH3 and multiple ankyrin repeat domains 10.056
Plcg1phospholipase C, gamma 10.054
Ndfip2Nedd4 family interacting protein 20.053
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.051
Castcalpastatin0.050
Fbxo30F-box protein 300.050
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.050
Pfn1profilin 10.047
Mmp3matrix metallopeptidase 30.047
Gtf2a1general transcription factor IIA, 10.046
Ascl2achaete-scute complex homolog 2 (Drosophila)0.046
Prph2peripherin 20.046
Sec24dSEC24 family, member D (S. cerevisiae)0.045
Dnm1dynamin 10.044
Robo2roundabout homolog 2 (Drosophila)0.043
Prkchprotein kinase C, eta0.041
Ap2a1adaptor-related protein complex 2, alpha 1 subunit0.040
Fgf2fibroblast growth factor 20.040
Efhd2EF-hand domain family, member D20.039
Nudt16l1nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 10.039
Dlgap1discs, large (Drosophila) homolog-associated protein 10.039
Lect1leukocyte cell derived chemotaxin 10.038
Acrv1acrosomal vesicle protein 10.038
Galgalanin prepropeptide0.038
RfngRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase0.037
Gpr1G protein-coupled receptor 10.036
Arcn1archain 10.036
Efna5ephrin A50.034
Mmp9matrix metallopeptidase 90.034
Platplasminogen activator, tissue0.034
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.033
Ucp2uncoupling protein 2 (mitochondrial, proton carrier)0.033
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.033
Lifleukemia inhibitory factor0.032
Scarb1scavenger receptor class B, member 10.032
Il1rninterleukin 1 receptor antagonist0.032
MrgprfMAS-related GPR, member F0.031
Ncaph2non-SMC condensin II complex, subunit H20.031
Mertkc-mer proto-oncogene tyrosine kinase0.031
Epha7Eph receptor A70.030
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.030
Dlgap3discs, large (Drosophila) homolog-associated protein 30.029
Il8rainterleukin 8 receptor, alpha0.029
Ptmaprothymosin alpha0.029
Arrb2arrestin, beta 20.029
Mapk10mitogen activated protein kinase 100.028
Adrb2adrenergic, beta-2-, receptor, surface0.028
Drd1adopamine receptor D1A0.027
Bak1BCL2-antagonist/killer 10.027
Gfra1GDNF family receptor alpha 10.026
Dio3deiodinase, iodothyronine, type III0.026
Foxa1forkhead box A10.026
Il1r1interleukin 1 receptor, type I0.026
Cd46CD46 molecule, complement regulatory protein0.026
Nlgn1neuroligin 10.026
Pcnxl3pecanex-like 3 (Drosophila)0.025
Il17reinterleukin 17 receptor E0.025
Kcnip4Kv channel interacting protein 40.025
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.025
Leprleptin receptor0.025
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PEX10Pex10p0.576
GDI1Gdi1p0.575
YPT1Ypt1p0.399
YPT10Ypt10p0.097
PEX1Pex1p0.081
YPT52Ypt52p0.074
PEX5Pex5p0.052
SLA2Sla2p0.049
PEX6Pex6p0.038
PEX22Pex22p0.037
AKL1Akl1p0.037
VPS21Vps21p0.034
TFA1Tfa1p0.031
PEX15Pex15p0.025
PEX14Pex14p0.024
UGO1Ugo1p0.023
PEX12Pex12p0.022
PEX4Pex4p0.022
ALY1Aly1p0.020
ARG8Arg8p0.020
TFB4Tfb4p0.020
VPS8Vps8p0.020
CCL1Ccl1p0.019
TRA1Tra1p0.015
FAB1Fab1p0.013
YBL039W-Bhypothetical protein0.013
ROG3Rog3p0.012
PEX8Pex8p0.012
SRD1Srd1p0.012
YLR264C-Ahypothetical protein0.011
CUP1-1Cup1-1p0.011
SEC21Sec21p0.011
LEU2Leu2p0.011
UBR2Ubr2p0.011
END3End3p0.011
PEX13Pex13p0.011
UPS3Ups3p0.011
YGR102Chypothetical protein0.010