The network for 'positive regulation of p38mapk cascade' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of p38mapk cascade

Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.

Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GADD45GIP1growth arrest and DNA-damage-inducible, gamma interacting protein 11.000
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide1.000
VEGFAvascular endothelial growth factor A1.000
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)1.000
NRP1neuropilin 11.000
BMPR1Abone morphogenetic protein receptor, type IA0.999
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.976
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.884
MIDNmidnolin0.876
MAP2K5mitogen-activated protein kinase kinase 50.862
RPS14ribosomal protein S140.676
TRAF7TNF receptor-associated factor 70.666
SH3KBP1SH3-domain kinase binding protein 10.580
PGFplacental growth factor0.543
FSTL1follistatin-like 10.420
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.353
MAP3K2mitogen-activated protein kinase kinase kinase 20.317
RPL37Aribosomal protein L37a0.312
RPS11ribosomal protein S110.308
PLCG1phospholipase C, gamma 10.279
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.274
BHLHE40basic helix-loop-helix family, member e400.271
SH3GLB1SH3-domain GRB2-like endophilin B10.267
MAP3K4mitogen-activated protein kinase kinase kinase 40.252
DCTN2dynactin 2 (p50)0.222
PTPRBprotein tyrosine phosphatase, receptor type, B0.219
PDGFCplatelet derived growth factor C0.160
SPRY2sprouty homolog 2 (Drosophila)0.129
MARK2MAP/microtubule affinity-regulating kinase 20.123
DDIT4DNA-damage-inducible transcript 40.104
RPS28ribosomal protein S280.102
JMJD1Cjumonji domain containing 1C0.101
FLNAfilamin A, alpha0.097
NOGnoggin0.091
RPS27Aribosomal protein S27a0.084
FLNBfilamin B, beta0.070
MAP2K6mitogen-activated protein kinase kinase 60.060
SQSTM1sequestosome 10.056
GADD45Bgrowth arrest and DNA-damage-inducible, beta0.055
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.043
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.041
RPL11ribosomal protein L110.040
STC1stanniocalcin 10.039
ZFYVE9zinc finger, FYVE domain containing 90.036
CSRNP1cysteine-serine-rich nuclear protein 10.035
CYR61cysteine-rich, angiogenic inducer, 610.034
CEP110centrosomal protein 110kDa0.033
IER2immediate early response 20.032
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.029
FOSL2FOS-like antigen 20.028
RPS27ribosomal protein S270.024
COL4A1collagen, type IV, alpha 10.022
MYO1Cmyosin IC0.022
ROBO4roundabout homolog 4, magic roundabout (Drosophila)0.020
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.020
MAPK7mitogen-activated protein kinase 70.020
LMO4LIM domain only 40.017
KLF10Kruppel-like factor 100.016
COL2A1collagen, type II, alpha 10.016
ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 30.015
NFIL3nuclear factor, interleukin 3 regulated0.015
BMPR1Bbone morphogenetic protein receptor, type IB0.015
BMP4bone morphogenetic protein 40.015
RPS15Aribosomal protein S15a0.014
BMP2bone morphogenetic protein 20.014
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.013
FZD4frizzled homolog 4 (Drosophila)0.013
SLC28A3solute carrier family 28 (sodium-coupled nucleoside transporter), member 30.013
MT1Emetallothionein 1E0.012
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.012
RDH13retinol dehydrogenase 13 (all-trans/9-cis)0.012
MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)0.012
PIM1pim-1 oncogene0.011
DOK2docking protein 2, 56kDa0.011
LDLRlow density lipoprotein receptor0.011
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.011
SH3GL2SH3-domain GRB2-like 20.011
SH3GL3SH3-domain GRB2-like 30.011
GSK3Bglycogen synthase kinase 3 beta0.011
PPP1R15Aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.011
FSTfollistatin0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.691
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.590
Tgfbr2transforming growth factor, beta receptor II0.513
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.470
Fgfr2fibroblast growth factor receptor 20.437
Acvr1activin A receptor, type 10.416
Ptpn11protein tyrosine phosphatase, non-receptor type 110.398
Ece1endothelin converting enzyme 10.385
Bmp4bone morphogenetic protein 40.349
Itgb1integrin beta 1 (fibronectin receptor beta)0.271
Tgfb2transforming growth factor, beta 20.258
Gja1gap junction protein, alpha 10.254
Sox9SRY-box containing gene 90.214
Prrx1paired related homeobox 10.177
Ednraendothelin receptor type A0.128
FasFas (TNF receptor superfamily member 6)0.097
Ptgs2prostaglandin-endoperoxide synthase 20.085
Foxc1forkhead box C10.084
Nos3nitric oxide synthase 3, endothelial cell0.081
Notch2Notch gene homolog 2 (Drosophila)0.074
Foxc2forkhead box C20.073
Csf1colony stimulating factor 1 (macrophage)0.064
Smosmoothened homolog (Drosophila)0.060
Ctnnb1catenin (cadherin associated protein), beta 10.059
Ptch1patched homolog 10.054
JunbJun-B oncogene0.051
Jag1jagged 10.048
Dusp1dual specificity phosphatase 10.046
Rarbretinoic acid receptor, beta0.045
Trp53transformation related protein 530.044
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.044
Kdrkinase insert domain protein receptor0.043
Gadd45ggrowth arrest and DNA-damage-inducible 45 gamma0.041
Leprleptin receptor0.040
Errfi1ERBB receptor feedback inhibitor 10.039
XiapX-linked inhibitor of apoptosis0.039
Ppargperoxisome proliferator activated receptor gamma0.039
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.037
Psen1presenilin 10.033
Cd151CD151 antigen0.033
Bcl2B-cell leukemia/lymphoma 20.032
Cited2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.032
Adam17a disintegrin and metallopeptidase domain 170.031
FosFBJ osteosarcoma oncogene0.031
Map2k5mitogen-activated protein kinase kinase 50.029
Zfp36zinc finger protein 360.028
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.028
Wwtr1WW domain containing transcription regulator 10.027
Meox2mesenchyme homeobox 20.027
Apcadenomatosis polyposis coli0.026
Vhlvon Hippel-Lindau tumor suppressor0.026
Ier3immediate early response 30.026
BrafBraf transforming gene0.025
Sertad1SERTA domain containing 10.025
Atf3activating transcription factor 30.024
Nrp1neuropilin 10.024
JunJun oncogene0.024
Prkciprotein kinase C, iota0.023
Yap1yes-associated protein 10.023
Pvrpoliovirus receptor0.023
Stat3signal transducer and activator of transcription 30.022
Kif3akinesin family member 3A0.022
Apoeapolipoprotein E0.021
Tspan12tetraspanin 120.021
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.020
Bhlhe40basic helix-loop-helix family, member e400.020
Agtr1aangiotensin II receptor, type 1a0.019
Ptenphosphatase and tensin homolog0.018
Traf6TNF receptor-associated factor 60.018
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.017
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.017
Fgfr1fibroblast growth factor receptor 10.017
Smad1MAD homolog 1 (Drosophila)0.016
Fzd4frizzled homolog 4 (Drosophila)0.016
Mkl2MKL/myocardin-like 20.016
Rararetinoic acid receptor, alpha0.015
Atf4activating transcription factor 40.015
Maffv-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)0.015
Lcorligand dependent nuclear receptor corepressor0.015
Mafkv-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)0.015
Hoxa1homeobox A10.015
Fli1Friend leukemia integration 10.014
Nfil3nuclear factor, interleukin 3, regulated0.014
Fgfr3fibroblast growth factor receptor 30.014
Btg2B-cell translocation gene 2, anti-proliferative0.014
Ehd4EH-domain containing 40.013
Diap2diaphanous homolog 2 (Drosophila)0.013
Bmpr1abone morphogenetic protein receptor, type 1A0.013
Atp2a2ATPase, Ca++ transporting, cardiac muscle, slow twitch 20.013
Gadd45bgrowth arrest and DNA-damage-inducible 45 beta0.012
Admadrenomedullin0.012
Chd7chromodomain helicase DNA binding protein 70.012
Egr1early growth response 10.012
Ilkintegrin linked kinase0.012
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.012
Arid5bAT rich interactive domain 5B (MRF1-like)0.011
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.011
Lrp6low density lipoprotein receptor-related protein 60.011
Prkd2protein kinase D20.011
Phlda1pleckstrin homology-like domain, family A, member 10.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism