The network for 'alpha beta t cell differentiation involved in immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

alpha beta t cell differentiation involved in immune response

The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.

NameDescriptionProbabilityFunc Analog Organism
IL4Rinterleukin 4 receptor0.999
LIN9lin-9 homolog (C. elegans)0.622
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.573
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.544
IL2RGinterleukin 2 receptor, gamma0.445
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.397
NCOR2nuclear receptor corepressor 20.371
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.285
NR0B1nuclear receptor subfamily 0, group B, member 10.275
SIN3ASIN3 homolog A, transcription regulator (yeast)0.243
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.195
IL23Ainterleukin 23, alpha subunit p190.164
RXRAretinoid X receptor, alpha0.157
STAT6signal transducer and activator of transcription 6, interleukin-4 induced0.127
MED25mediator complex subunit 250.086
PDZD11PDZ domain containing 110.078
NLKnemo-like kinase0.067
PPARAperoxisome proliferator-activated receptor alpha0.052
LIN54lin-54 homolog (C. elegans)0.049
NCOA1nuclear receptor coactivator 10.048
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.043
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.033
IL4interleukin 40.031
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.030
CD247CD247 molecule0.024
BCL3B-cell CLL/lymphoma 30.023
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.021
RARAretinoic acid receptor, alpha0.018
IL6Rinterleukin 6 receptor0.018
PMLpromyelocytic leukemia0.018
TMEM173transmembrane protein 1730.013
CXCL2chemokine (C-X-C motif) ligand 20.013
IL8interleukin 80.012
JUNBjun B proto-oncogene0.012
PLXND1plexin D10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1001.000
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.997
Stat3signal transducer and activator of transcription 30.997
Tnftumor necrosis factor0.996
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.993
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.991
Socs1suppressor of cytokine signaling 10.989
Cd40CD40 antigen0.986
Tnfaip3tumor necrosis factor, alpha-induced protein 30.985
Ccl2chemokine (C-C motif) ligand 20.977
Leprleptin receptor0.977
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.975
Bcl3B-cell leukemia/lymphoma 30.973
Il1r1interleukin 1 receptor, type I0.968
Jak2Janus kinase 20.957
Pax2paired box gene 20.954
Lef1lymphoid enhancer binding factor 10.948
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.947
Ifnginterferon gamma0.937
Socs3suppressor of cytokine signaling 30.934
Tbx3T-box 30.931
Stat5asignal transducer and activator of transcription 5A0.917
Il4rainterleukin 4 receptor, alpha0.870
FasFas (TNF receptor superfamily member 6)0.868
Irf9interferon regulatory factor 90.851
Ccl4chemokine (C-C motif) ligand 40.829
Stat6signal transducer and activator of transcription 60.786
Cishcytokine inducible SH2-containing protein0.739
Bcl2B-cell leukemia/lymphoma 20.735
Ptgs2prostaglandin-endoperoxide synthase 20.730
Ighimmunoglobulin heavy chain complex0.726
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.721
Stat2signal transducer and activator of transcription 20.708
Map3k8mitogen-activated protein kinase kinase kinase 80.704
Lyz2lysozyme 20.698
Il10interleukin 100.684
Myd88myeloid differentiation primary response gene 880.665
Ccl3chemokine (C-C motif) ligand 30.653
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.644
Stat5bsignal transducer and activator of transcription 5B0.639
Icam1intercellular adhesion molecule 10.606
Irf1interferon regulatory factor 10.599
Zeb1zinc finger E-box binding homeobox 10.596
Ccr1chemokine (C-C motif) receptor 10.591
Gata6GATA binding protein 60.590
Traf6TNF receptor-associated factor 60.588
Irf5interferon regulatory factor 50.586
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.572
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.564
Gli3GLI-Kruppel family member GLI30.559
Jag1jagged 10.557
Runx1runt related transcription factor 10.540
Wt1Wilms tumor 1 homolog0.524
Il10rainterleukin 10 receptor, alpha0.512
Ccl7chemokine (C-C motif) ligand 70.511
Sfpi1SFFV proviral integration 10.469
Nf1neurofibromatosis 10.457
Ccl12chemokine (C-C motif) ligand 120.455
Cxcl2chemokine (C-X-C motif) ligand 20.445
Cxcl10chemokine (C-X-C motif) ligand 100.418
Batfbasic leucine zipper transcription factor, ATF-like0.403
Ikzf1IKAROS family zinc finger 10.398
Foxp3forkhead box P30.392
Jak3Janus kinase 30.378
Il6interleukin 60.373
Fgfr2fibroblast growth factor receptor 20.369
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.357
Selpselectin, platelet0.355
Nos2nitric oxide synthase 2, inducible0.348
Rxraretinoid X receptor alpha0.346
Il1binterleukin 1 beta0.333
Ccr2chemokine (C-C motif) receptor 20.323
Rargretinoic acid receptor, gamma0.312
Cd86CD86 antigen0.304
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.299
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.295
Pitx2paired-like homeodomain transcription factor 20.294
Il4interleukin 40.292
Birc3baculoviral IAP repeat-containing 30.291
Ccr5chemokine (C-C motif) receptor 50.281
Tal1T-cell acute lymphocytic leukemia 10.272
Ch25hcholesterol 25-hydroxylase0.265
Hoxa1homeobox A10.262
Shhsonic hedgehog0.261
Pitx1paired-like homeodomain transcription factor 10.261
Mmp9matrix metallopeptidase 90.260
Rc3h1RING CCCH (C3H) domains 10.260
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.257
Irf4interferon regulatory factor 40.255
Pim1proviral integration site 10.254
Il17rainterleukin 17 receptor A0.248
Il6stinterleukin 6 signal transducer0.245
Fgf10fibroblast growth factor 100.234
Irf7interferon regulatory factor 70.226
Prdm1PR domain containing 1, with ZNF domain0.220
Cd44CD44 antigen0.218
Fgfr3fibroblast growth factor receptor 30.211
Nfkbienuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.194
Foxf1aforkhead box F1a0.189
Atxn1ataxin 10.185
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism