The network for 'regulation of dna repair' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of dna repair

Any process that modulates the frequency, rate or extent of DNA repair.

NameDescriptionProbabilityFunc Analog Organism
BRCA1breast cancer 1, early onset0.996
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.955
FGFR2fibroblast growth factor receptor 20.954
H2AFXH2A histone family, member X0.908
MDC1mediator of DNA-damage checkpoint 10.845
TNFSF14tumor necrosis factor (ligand) superfamily, member 140.767
CREBBPCREB binding protein0.675
BRCC3BRCA1/BRCA2-containing complex, subunit 30.665
FAM175Afamily with sequence similarity 175, member A0.619
SMEK1SMEK homolog 1, suppressor of mek1 (Dictyostelium)0.606
NBNnibrin0.541
RPA1replication protein A1, 70kDa0.532
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.452
ERCC6excision repair cross-complementing rodent repair deficiency, complementation group 60.430
NCF1neutrophil cytosolic factor 10.411
BREbrain and reproductive organ-expressed (TNFRSF1A modulator)0.390
CDK2cyclin-dependent kinase 20.359
APPamyloid beta (A4) precursor protein0.354
EGFRepidermal growth factor receptor0.333
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.314
SHC1SHC (Src homology 2 domain containing) transforming protein 10.309
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.290
CUL1cullin 10.280
FGFR1fibroblast growth factor receptor 10.280
PCNAproliferating cell nuclear antigen0.265
SETD8SET domain containing (lysine methyltransferase) 80.264
BRCA2breast cancer 2, early onset0.258
RB1retinoblastoma 10.242
LRP1low density lipoprotein receptor-related protein 10.242
DDIT3DNA-damage-inducible transcript 30.235
UIMC1ubiquitin interaction motif containing 10.230
WRNWerner syndrome, RecQ helicase-like0.229
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.216
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.197
PPP2R5Bprotein phosphatase 2, regulatory subunit B', beta0.188
CCNE1cyclin E10.180
EP300E1A binding protein p3000.179
SKILSKI-like oncogene0.173
RAD52RAD52 homolog (S. cerevisiae)0.172
DNAJC9DnaJ (Hsp40) homolog, subfamily C, member 90.170
MDM4Mdm4 p53 binding protein homolog (mouse)0.166
GSK3Bglycogen synthase kinase 3 beta0.166
NOXA1NADPH oxidase activator 10.156
BLMBloom syndrome, RecQ helicase-like0.154
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)0.145
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.133
TOPBP1topoisomerase (DNA) II binding protein 10.126
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.122
MAGEA2melanoma antigen family A, 20.113
BABAM1BRISC and BRCA1 A complex member 10.112
RNF11ring finger protein 110.109
PRKCZprotein kinase C, zeta0.107
ZNRF1zinc and ring finger 10.106
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.103
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.102
ARNTLaryl hydrocarbon receptor nuclear translocator-like0.101
CSNK2A1casein kinase 2, alpha 1 polypeptide0.100
SMC2structural maintenance of chromosomes 20.099
CCNA2cyclin A20.097
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.095
REV3LREV3-like, catalytic subunit of DNA polymerase zeta (yeast)0.094
MEN1multiple endocrine neoplasia I0.090
DLG4discs, large homolog 4 (Drosophila)0.088
RFWD2ring finger and WD repeat domain 20.087
FGF10fibroblast growth factor 100.086
PRMT6protein arginine methyltransferase 60.084
TCF12transcription factor 120.083
DMC1DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)0.074
WDHD1WD repeat and HMG-box DNA binding protein 10.074
CDK1cyclin-dependent kinase 10.072
HDAC1histone deacetylase 10.072
RAD1RAD1 homolog (S. pombe)0.069
BARD1BRCA1 associated RING domain 10.069
GTF2H2general transcription factor IIH, polypeptide 2, 44kDa0.068
POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa0.067
SMAD7SMAD family member 70.066
SETD7SET domain containing (lysine methyltransferase) 70.066
GATA2GATA binding protein 20.064
RUNX1runt-related transcription factor 10.064
UBR5ubiquitin protein ligase E3 component n-recognin 50.063
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.063
RAD18RAD18 homolog (S. cerevisiae)0.061
PARP1poly (ADP-ribose) polymerase 10.061
FGF1fibroblast growth factor 1 (acidic)0.060
TSC22D1TSC22 domain family, member 10.059
FANCD2Fanconi anemia, complementation group D20.059
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.059
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.058
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.057
SUPT6Hsuppressor of Ty 6 homolog (S. cerevisiae)0.056
TP53BP1tumor protein p53 binding protein 10.056
HIPK2homeodomain interacting protein kinase 20.055
TIMELESStimeless homolog (Drosophila)0.054
CLSPNclaspin0.054
UBXN1UBX domain protein 10.053
FGF7fibroblast growth factor 70.050
SUPT16Hsuppressor of Ty 16 homolog (S. cerevisiae)0.050
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.049
DDB1damage-specific DNA binding protein 1, 127kDa0.049
RNF8ring finger protein 80.048
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
DNApol-etaCG7143 gene product from transcript CG7143-RA0.560
CG5524CG5524 gene product from transcript CG5524-RA0.544
lokloki0.495
mus205mutagen-sensitive 2050.347
Klp3AKinesin-like protein at 3A0.202
hydhyperplastic discs0.170
CG9772CG9772 gene product from transcript CG9772-RB0.149
hayhaywire0.148
mus309mutagen-sensitive 3090.143
cutletCG33122 gene product from transcript CG33122-RA0.141
Brca2Breast cancer 2, early onset homolog0.141
mus101mutagen-sensitive 1010.128
armiarmitage0.116
rad50CG6339 gene product from transcript CG6339-RD0.109
panpangolin0.106
CG4680CG4680 gene product from transcript CG4680-RA0.103
Smc5CG32438 gene product from transcript CG32438-RE0.090
arrarrow0.085
mus301mutagen-sensitive 3010.082
dmtdalmatian0.078
tefutelomere fusion0.075
mus308mutagen-sensitive 3080.071
CG13900CG13900 gene product from transcript CG13900-RA0.061
Mcm3Minichromosome maintenance 30.057
mei-9meiotic 90.041
nopono poles0.035
RecQ5homolog of RecQ0.029
ykiyorkie0.026
CG7376CG7376 gene product from transcript CG7376-RA0.025
p53CG33336 gene product from transcript CG33336-RB0.024
mus312mutagen-sensitive 3120.022
Df31Decondensation factor 310.022
IncenpInner centromere protein0.020
CG1239CG1239 gene product from transcript CG1239-RA0.019
Smg6CG6369 gene product from transcript CG6369-RA0.019
alphalphabet0.018
CDC45LCG3658 gene product from transcript CG3658-RA0.017
pblpebble0.016
Rev1CG12189 gene product from transcript CG12189-RA0.016
nbsCG6754 gene product from transcript CG6754-RC0.016
CG4266CG4266 gene product from transcript CG4266-RA0.016
CG2694CG2694 gene product from transcript CG2694-RA0.015
Taf8TBP-associated factor 80.015
HmgcrHMG Coenzyme A reductase0.015
hephhephaestus0.013
gppgrappa0.013
l(2)dtllethal-(2)-denticleless0.013
CG14965CG14965 gene product from transcript CG14965-RA0.013
pngpan gu0.013
CG11403CG11403 gene product from transcript CG11403-RA0.012
cuffcutoff0.012
MBD-R2CG10042 gene product from transcript CG10042-RB0.012
E(var)3-9Enhancer of variegation 3-90.011
PcPolycomb0.011
CycJCyclin J0.011
IrbpInverted repeat-binding protein0.011
RalaRas-related protein0.010
piepineapple eye0.010
mus304mutagen-sensitive 3040.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.056
Brca2breast cancer 20.031
Arntlaryl hydrocarbon receptor nuclear translocator-like0.015
SkilSKI-like0.014
Cdk4cyclin-dependent kinase 40.014
Mdm2transformed mouse 3T3 cell double minute 20.013
Brca1breast cancer 10.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Rps12ribosomal protein S120.016
Rpl23ribosomal protein L230.012
Rpl27ribosomal protein L270.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RTF1Rtf1p0.612
PSY4Psy4p0.510
PPH21Pph21p0.463
CTR9Ctr9p0.446
LEO1Leo1p0.247
SPT16Spt16p0.229
CKA1Cka1p0.193
RAD52Rad52p0.184
CDC55Cdc55p0.157
TPD3Tpd3p0.138
RAD23Rad23p0.135
RFA1Rfa1p0.131
RAD5Rad5p0.110
PAF1Paf1p0.097
SPT5Spt5p0.088
SSN3Ssn3p0.080
DNA2Dna2p0.059
UBC13Ubc13p0.053
MEC1Mec1p0.048
REV7Rev7p0.048
HHO1Hho1p0.047
HRR25Hrr25p0.038
RPS5Rps5p0.035
BRO1Bro1p0.033
IES1Ies1p0.033
CUP9Cup9p0.033
OPY2Opy2p0.033
SGS1Sgs1p0.033
SPT2Spt2p0.033
SIZ1Siz1p0.033
RAD55Rad55p0.030
CKB1Ckb1p0.027
RAD30Rad30p0.027
HAL5Hal5p0.027
RPB11Rpb11p0.026
ROX1Rox1p0.025
VPS27Vps27p0.023
POB3Pob3p0.023
PPH22Pph22p0.023
SAK1Sak1p0.022
FAR11Far11p0.022
RIO2Rio2p0.022
CAB3Cab3p0.021
SPT6Spt6p0.021
TIP41Tip41p0.020
IRA2Ira2p0.020
YKU70Yku70p0.019
POG1Pog1p0.019
VPS60Vps60p0.019
YPL150Whypothetical protein0.018
NHP6ANhp6ap0.018
YHR033Whypothetical protein0.018
TOR1Tor1p0.018
SUB1Sub1p0.017
RHO1Rho1p0.017
PRR2Prr2p0.017
LEU2Leu2p0.017
PCL9Pcl9p0.017
UBC4Ubc4p0.016
SRD1Srd1p0.016
VPS41Vps41p0.016
GCN2Gcn2p0.016
PTR3Ptr3p0.016
YLR264C-Ahypothetical protein0.015
CKS1Cks1p0.015
PCM1Pcm1p0.015
YDR034W-Bhypothetical protein0.015
DST1Dst1p0.015
ARE2Are2p0.015
RIM13Rim13p0.015
RMI1Rmi1p0.015
AAD6Aad6p0.014
RIM101Rim101p0.014
RAD53Rad53p0.014
YOL038C-Ahypothetical protein0.014
TYE7Tye7p0.014
YLR419Whypothetical protein0.014
MYO5Myo5p0.014
GYL1Gyl1p0.013
SLX8Slx8p0.013
ARP10Arp10p0.013
PHO81Pho81p0.013
KIC1Kic1p0.013
LEM3Lem3p0.013
YLR162Whypothetical protein0.013
HOHop0.013
YAR068Whypothetical protein0.013
NRD1Nrd1p0.013
MER1Mer1p0.013
YIR035Chypothetical protein0.013
ELF1Elf1p0.013
PRE2Pre2p0.013
PHO80Pho80p0.013
SNF7Snf7p0.012
CUP1-1Cup1-1p0.012
TOP3Top3p0.012
ZPS1Zps1p0.012
PTP3Ptp3p0.012
CTK3Ctk3p0.012
HDA2Hda2p0.012