The network for 'fibroblast proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

fibroblast proliferation

The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.

NameDescriptionProbabilityFunc Analog Organism
RING1ring finger protein 10.998
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.997
VEGFAvascular endothelial growth factor A0.994
RNF2ring finger protein 20.981
RB1retinoblastoma 10.916
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.914
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.895
BCL2L11BCL2-like 11 (apoptosis facilitator)0.842
MDM2Mdm2 p53 binding protein homolog (mouse)0.797
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.737
CBX7chromobox homolog 70.729
CBX8chromobox homolog 80.703
FTLferritin, light polypeptide0.636
APLFaprataxin and PNKP like factor0.630
RYBPRING1 and YY1 binding protein0.620
PLAUplasminogen activator, urokinase0.601
NAMPTnicotinamide phosphoribosyltransferase0.581
CCND1cyclin D10.571
CBX6chromobox homolog 60.546
DTX3Ldeltex 3-like (Drosophila)0.520
RBL2retinoblastoma-like 2 (p130)0.501
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.456
PARP9poly (ADP-ribose) polymerase family, member 90.436
PCGF2polycomb group ring finger 20.422
USP11ubiquitin specific peptidase 110.417
FTH1ferritin, heavy polypeptide 10.417
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.407
TFDP2transcription factor Dp-2 (E2F dimerization partner 2)0.400
AXLAXL receptor tyrosine kinase0.397
TFDP1transcription factor Dp-10.384
CDK2cyclin-dependent kinase 20.357
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.348
PARP14poly (ADP-ribose) polymerase family, member 140.339
XRCC4X-ray repair complementing defective repair in Chinese hamster cells 40.334
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.327
BMI1BMI1 polycomb ring finger oncogene0.312
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.283
UHRF2ubiquitin-like with PHD and ring finger domains 20.282
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.280
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.276
E2F1E2F transcription factor 10.256
NRP1neuropilin 10.242
LIG4ligase IV, DNA, ATP-dependent0.237
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.212
MAP3K5mitogen-activated protein kinase kinase kinase 50.210
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.204
PDGFAplatelet-derived growth factor alpha polypeptide0.188
CCND3cyclin D30.183
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.172
CBX4chromobox homolog 40.163
TFF1trefoil factor 10.142
CDK6cyclin-dependent kinase 60.139
MAXMYC associated factor X0.135
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.132
MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)0.129
CDH5cadherin 5, type 2 (vascular endothelium)0.128
RNF144Bring finger protein 144B0.126
NFIL3nuclear factor, interleukin 3 regulated0.117
BHLHE40basic helix-loop-helix family, member e400.113
PCGF5polycomb group ring finger 50.108
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.105
TP53tumor protein p530.105
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.099
BCORBCL6 corepressor0.098
CTSBcathepsin B0.095
E2F4E2F transcription factor 4, p107/p130-binding0.092
E2F2E2F transcription factor 20.089
BADBCL2-associated agonist of cell death0.088
S100BS100 calcium binding protein B0.087
E2F6E2F transcription factor 60.082
CUX1cut-like homeobox 10.082
RXRAretinoid X receptor, alpha0.081
E2F3E2F transcription factor 30.078
CCND2cyclin D20.074
PDGFCplatelet derived growth factor C0.073
COL6A1collagen, type VI, alpha 10.065
CCNE1cyclin E10.065
ATF2activating transcription factor 20.065
AHRaryl hydrocarbon receptor0.064
UQCRBubiquinol-cytochrome c reductase binding protein0.062
CXCR4chemokine (C-X-C motif) receptor 40.061
HLA-DMBmajor histocompatibility complex, class II, DM beta0.059
NFIXnuclear factor I/X (CCAAT-binding transcription factor)0.059
CKS1BCDC28 protein kinase regulatory subunit 1B0.058
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.057
JUNBjun B proto-oncogene0.057
SIRT1sirtuin 10.055
COPS6COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)0.053
IGF2Rinsulin-like growth factor 2 receptor0.052
IGFBP5insulin-like growth factor binding protein 50.052
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.051
FOSL1FOS-like antigen 10.050
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.050
STMN2stathmin-like 20.047
CDC27cell division cycle 27 homolog (S. cerevisiae)0.047
COL11A2collagen, type XI, alpha 20.046
CABLES1Cdk5 and Abl enzyme substrate 10.045
BAK1BCL2-antagonist/killer 10.045
ITGB1BP3integrin beta 1 binding protein 30.045
LGALS8lectin, galactoside-binding, soluble, 80.044
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 531.000
Ptenphosphatase and tensin homolog0.989
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.952
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.941
Rararetinoic acid receptor, alpha0.894
Pbx1pre B-cell leukemia transcription factor 10.855
Tgfb1transforming growth factor, beta 10.756
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.643
Cdkn1bcyclin-dependent kinase inhibitor 1B0.639
Gli3GLI-Kruppel family member GLI30.638
FosFBJ osteosarcoma oncogene0.609
JunJun oncogene0.595
Fgfr1fibroblast growth factor receptor 10.571
Leprleptin receptor0.508
C1qacomplement component 1, q subcomponent, alpha polypeptide0.505
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.498
Sp1trans-acting transcription factor 10.487
Stat3signal transducer and activator of transcription 30.446
Mdm4transformed mouse 3T3 cell double minute 40.434
Apcadenomatosis polyposis coli0.430
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.414
Shhsonic hedgehog0.406
Mcl1myeloid cell leukemia sequence 10.392
Fgfr2fibroblast growth factor receptor 20.348
Retret proto-oncogene0.338
Trp63transformation related protein 630.336
Nrg1neuregulin 10.327
Fgf8fibroblast growth factor 80.315
Rxraretinoid X receptor alpha0.312
Mdm2transformed mouse 3T3 cell double minute 20.302
C1qccomplement component 1, q subcomponent, C chain0.301
Maffv-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)0.300
Kitkit oncogene0.293
Nfe2l2nuclear factor, erythroid derived 2, like 20.291
Ptpn11protein tyrosine phosphatase, non-receptor type 110.291
H2-Aahistocompatibility 2, class II antigen A, alpha0.272
Csf1colony stimulating factor 1 (macrophage)0.271
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.263
Arandrogen receptor0.259
Ciccapicua homolog (Drosophila)0.258
Notch2Notch gene homolog 2 (Drosophila)0.252
Polr2apolymerase (RNA) II (DNA directed) polypeptide A0.244
Smad3MAD homolog 3 (Drosophila)0.232
Egr1early growth response 10.213
Bcl2B-cell leukemia/lymphoma 20.208
Ccnd2cyclin D20.208
Spry4sprouty homolog 4 (Drosophila)0.198
Hoxa9homeobox A90.198
Ccnd1cyclin D10.193
Mapk14mitogen-activated protein kinase 140.184
Bdnfbrain derived neurotrophic factor0.182
Rarbretinoic acid receptor, beta0.175
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.172
Isl1ISL1 transcription factor, LIM/homeodomain0.168
TyrobpTYRO protein tyrosine kinase binding protein0.165
Pax3paired box gene 30.164
Atf3activating transcription factor 30.160
Pax6paired box gene 60.158
Prrx1paired related homeobox 10.158
Nf1neurofibromatosis 10.154
Cdk1cyclin-dependent kinase 10.150
Mapk8mitogen-activated protein kinase 80.149
Wnt5awingless-related MMTV integration site 5A0.146
Egr2early growth response 20.142
Ptgs2prostaglandin-endoperoxide synthase 20.138
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.134
Sox9SRY-box containing gene 90.130
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.129
Ntf3neurotrophin 30.129
Runx1runt related transcription factor 10.127
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.120
H2-Eb1histocompatibility 2, class II antigen E beta0.110
Wt1Wilms tumor 1 homolog0.109
Ftl1ferritin light chain 10.109
MaxMax protein0.108
Ep300E1A binding protein p3000.108
Lifleukemia inhibitory factor0.107
Csf1rcolony stimulating factor 1 receptor0.105
Sfrp2secreted frizzled-related protein 20.103
Cdkn2acyclin-dependent kinase inhibitor 2A0.102
Hbegfheparin-binding EGF-like growth factor0.101
Kiss1KiSS-1 metastasis-suppressor0.099
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.098
Sema6dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.096
Btg2B-cell translocation gene 2, anti-proliferative0.094
Nos3nitric oxide synthase 3, endothelial cell0.094
Trp73transformation related protein 730.093
Ppargperoxisome proliferator activated receptor gamma0.093
Zfp36zinc finger protein 360.092
Nr0b1nuclear receptor subfamily 0, group B, member 10.092
Tnfaip3tumor necrosis factor, alpha-induced protein 30.088
Lmnalamin A0.087
Zfp830zinc finger protein 8300.086
Rbl1retinoblastoma-like 1 (p107)0.085
Vdrvitamin D receptor0.084
Tcf21transcription factor 210.084
Apoeapolipoprotein E0.084
Mll1myeloid/lymphoid or mixed-lineage leukemia 10.083
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Anxa5annexin A50.078
Lgals3lectin, galactoside-binding, soluble, 30.033
Gja5gap junction protein, alpha 50.026
Cps1carbamoyl-phosphate synthetase 10.025
Gja1gap junction protein, alpha 10.024
Ctsjcathepsin J0.020
Calcbcalcitonin-related polypeptide, beta0.019
Ctsbcathepsin B0.018
Il1ainterleukin 1 alpha0.018
RT1-BaRT1 class II, locus Ba0.017
Apoa5apolipoprotein A-V0.016
Mbl1mannose-binding lectin (protein A) 10.016
S1pr2sphingosine-1-phosphate receptor 20.015
Esr1estrogen receptor 10.015
Slco2b1solute carrier organic anion transporter family, member 2b10.015
Nrg1neuregulin 10.015
RT1-DaRT1 class II, locus Da0.015
Cxcl2chemokine (C-X-C motif) ligand 20.015
S100a10S100 calcium binding protein A100.014
A3galt2alpha 1,3-galactosyltransferase 20.014
Slc5a5solute carrier family 5 (sodium iodide symporter), member 50.013
Hspb1heat shock protein 10.013
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.013
Darsaspartyl-tRNA synthetase0.013
Trim47tripartite motif-containing 470.013
LOC100364500RT1 class I, locus CE11-like0.012
Asgr1asialoglycoprotein receptor 10.012
Il1rl1interleukin 1 receptor-like 10.012
Cd80Cd80 molecule0.012
Dhdpsldihydrodipicolinate synthase-like, mitochondrial0.012
P2ry4pyrimidinergic receptor P2Y, G-protein coupled, 40.012
Hspa1aheat shock 70kD protein 1A0.012
Il8rbinterleukin 8 receptor, beta0.012
Psgb1pregnancy-specific beta 1-glycoprotein0.012
Foxo3forkhead box O30.012
Tshbthyroid stimulating hormone, beta0.011
Nraddneurotrophin receptor associated death domain0.011
Pik3ip1phosphoinositide-3-kinase interacting protein 10.011
Tbxa2rthromboxane A2 receptor0.011
Fgafibrinogen alpha chain0.011
Mmp10matrix metallopeptidase 100.011
Nos3nitric oxide synthase 3, endothelial cell0.011
Igfbp5insulin-like growth factor binding protein 50.011
Orm1orosomucoid 10.011
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.011
Ubbubiquitin B0.011
CebpeCCAAT/enhancer binding protein (C/EBP), epsilon0.011
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.011
Cd151CD151 molecule (Raph blood group)0.011
Cox4i2cytochrome c oxidase subunit IV isoform 20.010
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.010
Ptgfrprostaglandin F receptor0.010
Cd9CD9 molecule0.010
Arpc1bactin related protein 2/3 complex, subunit 1B0.010
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.010
Selpselectin P0.010
Il9rinterleukin 9 receptor0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism