The network for 'regulation of hormone metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of hormone metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.

NameDescriptionProbabilityFunc Analog Organism
TAL1T-cell acute lymphocytic leukemia 10.967
EPAS1endothelial PAS domain protein 10.955
AKR1C1aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)0.942
AKR1C2aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)0.911
BMPR1Abone morphogenetic protein receptor, type IA0.665
GH1growth hormone 10.538
CSH1chorionic somatomammotropin hormone 1 (placental lactogen)0.473
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.427
CSHL1chorionic somatomammotropin hormone-like 10.403
AHRaryl hydrocarbon receptor0.392
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.314
AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)0.303
GH2growth hormone 20.293
CSH2chorionic somatomammotropin hormone 20.284
EGLN1egl nine homolog 1 (C. elegans)0.260
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.219
MEOX1mesenchyme homeobox 10.207
BMPR1Bbone morphogenetic protein receptor, type IB0.200
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.160
EGLN3egl nine homolog 3 (C. elegans)0.156
ITGB1BP3integrin beta 1 binding protein 30.146
VHLvon Hippel-Lindau tumor suppressor0.142
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.117
CLOCKclock homolog (mouse)0.114
ARNTaryl hydrocarbon receptor nuclear translocator0.113
ESR1estrogen receptor 10.111
ARandrogen receptor0.109
IGF2Rinsulin-like growth factor 2 receptor0.108
TBX5T-box 50.085
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.075
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.073
SSX4synovial sarcoma, X breakpoint 40.071
NKX2-1NK2 homeobox 10.069
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.066
SMAD3SMAD family member 30.061
RUNX1runt-related transcription factor 10.057
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 10.055
TGFB1transforming growth factor, beta 10.052
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.043
SGK3serum/glucocorticoid regulated kinase family, member 30.042
RCOR1REST corepressor 10.042
CREBBPCREB binding protein0.041
ARHGEF40Rho guanine nucleotide exchange factor (GEF) 400.040
HIC1hypermethylated in cancer 10.038
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.038
ARHGAP22Rho GTPase activating protein 220.038
SFRP1secreted frizzled-related protein 10.035
SH3GL3SH3-domain GRB2-like 30.035
FGF4fibroblast growth factor 40.033
PRKCQprotein kinase C, theta0.029
CD2CD2 molecule0.029
BMP4bone morphogenetic protein 40.028
ALX4ALX homeobox 40.027
TCF4transcription factor 40.027
NDRG1N-myc downstream regulated 10.026
KLF13Kruppel-like factor 130.026
FGF18fibroblast growth factor 180.026
METmet proto-oncogene (hepatocyte growth factor receptor)0.026
COL2A1collagen, type II, alpha 10.024
SOX1SRY (sex determining region Y)-box 10.024
MTA3metastasis associated 1 family, member 30.023
GRB10growth factor receptor-bound protein 100.023
GDNFglial cell derived neurotrophic factor0.022
FAF1Fas (TNFRSF6) associated factor 10.022
MMP11matrix metallopeptidase 11 (stromelysin 3)0.021
FSTL1follistatin-like 10.021
SFRP5secreted frizzled-related protein 50.020
NRP1neuropilin 10.020
PRMT6protein arginine methyltransferase 60.020
FBLN1fibulin 10.020
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.020
BLNKB-cell linker0.020
SH3GL2SH3-domain GRB2-like 20.019
GATA2GATA binding protein 20.019
CYP19A1cytochrome P450, family 19, subfamily A, polypeptide 10.018
GLP1Rglucagon-like peptide 1 receptor0.017
TRAF4TNF receptor-associated factor 40.016
WNT10Awingless-type MMTV integration site family, member 10A0.016
FOXE1forkhead box E1 (thyroid transcription factor 2)0.016
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.015
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.015
PAX7paired box 70.014
BAG1BCL2-associated athanogene0.014
TUBB2Btubulin, beta 2B0.014
SPRY2sprouty homolog 2 (Drosophila)0.014
PAX3paired box 30.014
TP73tumor protein p730.014
IHHIndian hedgehog0.013
NEDD9neural precursor cell expressed, developmentally down-regulated 90.013
LCKlymphocyte-specific protein tyrosine kinase0.013
CARHSP1calcium regulated heat stable protein 1, 24kDa0.013
TAF1DTATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa0.013
HOXB1homeobox B10.013
WT1Wilms tumor 10.013
HSPA1Bheat shock 70kDa protein 1B0.012
SPIBSpi-B transcription factor (Spi-1/PU.1 related)0.012
PDCD6IPprogrammed cell death 6 interacting protein0.012
ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 30.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sox9bSRY-box containing gene 9b0.499
bmp2bbone morphogenetic protein 2b0.463
rspo1R-spondin homolog (Xenopus laevis)0.207
bmp4bone morphogenetic protein 40.189
ocrloculocerebrorenal syndrome of Lowe0.131
gro2groucho 20.129
paqr8progestin and adipoQ receptor family member VIII0.082
ephb4beph receptor B4b0.073
nanos3nanos homolog 30.073
axin1axin 10.070
tal1T-cell acute lymphocytic leukemia 10.066
rag1recombination activating gene 10.060
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.059
gpr126G protein-coupled receptor 1260.058
six2asine oculis-related homeobox 2a0.054
lhcgrluteinizing hormone/choriogonadotropin receptor0.053
inhainhibin, alpha0.042
trpm7transient receptor potential cation channel, subfamily M, member 70.041
LOC100000433hypothetical LOC1000004330.040
cx30.3connexin 30.30.038
hmx4H6 family homeobox 40.037
notch3notch homolog 30.036
plcg1phospholipase C, gamma 10.030
ptgs1prostaglandin-endoperoxide synthase 10.029
sf3b1splicing factor 3b, subunit 10.029
cldn2claudin 20.029
mt2metallothionein 20.029
hmx2H6 family homeobox 20.028
igf3insulin-like growth factor 30.028
cdh17cadherin 17, LI cadherin (liver-intestine)0.028
atp1a1a.4ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide0.028
lama5laminin, alpha 50.027
starsteroidogenic acute regulatory protein0.026
rorabRAR-related orphan receptor A, paralog b0.026
gpiaglucose phosphate isomerase a0.024
cyp17a1cytochrome P450, family 17, subfamily A, polypeptide 10.024
tp53bp2tumor protein p53 binding protein, 20.024
hsd17b12bhydroxysteroid (17-beta) dehydrogenase 12b0.022
vsx2visual system homeobox 20.021
hmx3homeo box (H6 family) 30.021
enc1ectodermal-neural cortex (with BTB-like domain)0.021
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.021
grifingalectin related inter-fiber protein0.020
evx1even-skipped homeobox 10.018
henmt1HEN1 methyltransferase homolog 1 (Arabidopsis)0.018
acvr2bactivin receptor IIb0.017
hsd17b1hydroxysteroid (17-beta) dehydrogenase 10.017
fzd5frizzled homolog 50.017
slc15a2solute carrier family 15 (H+/peptide transporter), member 20.016
kiss1KiSS-1 metastasis-suppressor0.015
fabp6fatty acid binding protein 6, ileal (gastrotropin)0.015
kiss1rbKISS1 receptor b0.015
aldh1a3aldehyde dehydrogenase 1 family, member A30.014
paqr7bprogestin and adipoQ receptor family member VII, b0.014
rykreceptor-like tyrosine kinase0.013
ndrg1N-myc downstream regulated gene 10.013
dachadachshund a0.013
wnt4bwingless-type MMTV integration site family, member 4b0.013
rx1retinal homeobox gene 10.012
ptgeslprostaglandin E synthase 2-like0.012
bambibBMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b0.012
wnt10awingless-type MMTV integration site family, member 10a0.012
slc12a3solute carrier family 12 (sodium/chloride transporters), member 30.011
bmp7bbone morphogenetic protein 7b0.011
jag2jagged 20.011
jag1bjagged 1b0.011
cldnaclaudin a0.011
notch1anotch homolog 1a0.011
ip6k2inositol hexaphosphate kinase 20.011
ascl1aachaete-scute complex-like 1a (Drosophila)0.011
gli1GLI-Kruppel family member 10.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pax8paired box gene 80.978
Esr1estrogen receptor 1 (alpha)0.524
Drd2dopamine receptor D20.376
Thrbthyroid hormone receptor beta0.353
Ush1gUsher syndrome 1G homolog (human)0.235
Fgfr2fibroblast growth factor receptor 20.199
Arandrogen receptor0.188
Fgf10fibroblast growth factor 100.184
Lhx1LIM homeobox protein 10.178
Ghrgrowth hormone receptor0.158
Wnt4wingless-related MMTV integration site 40.155
Kiss1KiSS-1 metastasis-suppressor0.146
Wnt9bwingless-type MMTV integration site 9B0.118
Bmp7bone morphogenetic protein 70.108
Tcf7transcription factor 7, T-cell specific0.104
Thrathyroid hormone receptor alpha0.088
Duox2dual oxidase 20.088
Ahraryl-hydrocarbon receptor0.088
Fgfr1fibroblast growth factor receptor 10.085
Adam17a disintegrin and metallopeptidase domain 170.083
Wnt3awingless-related MMTV integration site 3A0.077
Rargretinoic acid receptor, gamma0.076
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.076
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.070
Lmx1aLIM homeobox transcription factor 1 alpha0.070
Dkk1dickkopf homolog 1 (Xenopus laevis)0.070
Grb10growth factor receptor bound protein 100.065
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.065
Prlrprolactin receptor0.062
Retret proto-oncogene0.060
Pax2paired box gene 20.058
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.056
Wnt5awingless-related MMTV integration site 5A0.053
Slc17a8solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 80.049
Tmc1transmembrane channel-like gene family 10.043
Hoxd11homeobox D110.043
Igf2insulin-like growth factor 20.043
Pgrprogesterone receptor0.042
Alx4aristaless-like homeobox 40.041
Tbx1T-box 10.039
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.038
Shhsonic hedgehog0.037
Cdh23cadherin 23 (otocadherin)0.037
Emx2empty spiracles homolog 2 (Drosophila)0.036
Ror2receptor tyrosine kinase-like orphan receptor 20.036
Igf2rinsulin-like growth factor 2 receptor0.035
Rarbretinoic acid receptor, beta0.032
Sox9SRY-box containing gene 90.032
Rab25RAB25, member RAS oncogene family0.031
Wnt1wingless-related MMTV integration site 10.031
Amhr2anti-Mullerian hormone type 2 receptor0.031
Hoxa11homeobox A110.030
Wnt10bwingless related MMTV integration site 10b0.030
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.029
Lhx3LIM homeobox protein 30.029
Igf1insulin-like growth factor 10.028
Barx2BarH-like homeobox 20.027
Nkx2-1NK2 homeobox 10.026
Bglapbone gamma carboxyglutamate protein0.026
Lifleukemia inhibitory factor0.026
Insrinsulin receptor0.026
Hand1heart and neural crest derivatives expressed transcript 10.025
Pcsk4proprotein convertase subtilisin/kexin type 40.025
Plcb1phospholipase C, beta 10.025
Foxc1forkhead box C10.025
Kdm2blysine (K)-specific demethylase 2B0.025
Hoxa2homeobox A20.025
Foxi1forkhead box I10.024
Bnc1basonuclin 10.023
Epas1endothelial PAS domain protein 10.023
Tshrthyroid stimulating hormone receptor0.023
Cgaglycoprotein hormones, alpha subunit0.023
Cdkn1ccyclin-dependent kinase inhibitor 1C (P57)0.022
Bcl2B-cell leukemia/lymphoma 20.020
Gfi1bgrowth factor independent 1B0.020
Cbln3cerebellin 3 precursor protein0.020
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.020
Hbb-b1hemoglobin, beta adult major chain0.020
Fgf3fibroblast growth factor 30.020
4833422F24RikRIKEN cDNA 4833422F24 gene0.019
Cacnb2calcium channel, voltage-dependent, beta 2 subunit0.018
Adra2aadrenergic receptor, alpha 2a0.018
MgmtO-6-methylguanine-DNA methyltransferase0.018
Cacnb4calcium channel, voltage-dependent, beta 4 subunit0.018
Ryr1ryanodine receptor 1, skeletal muscle0.018
Onecut1one cut domain, family member 10.018
Gpc3glypican 30.017
Cacna1dcalcium channel, voltage-dependent, L type, alpha 1D subunit0.017
Trp63transformation related protein 630.017
Pcsk5proprotein convertase subtilisin/kexin type 50.017
Fshbfollicle stimulating hormone beta0.017
Nostrinnitric oxide synthase trafficker0.017
Fam83ffamily with sequence similarity 83, member F0.017
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.017
Porcnporcupine homolog (Drosophila)0.017
Fzd8frizzled homolog 8 (Drosophila)0.016
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism