The network for 'positive regulation of systemic arterial blood pressure' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of systemic arterial blood pressure

The process that increases the force with which blood travels through the systemic arterial circulatory system.

NameDescriptionProbabilityFunc Analog Organism
TGFB1transforming growth factor, beta 10.673
CRELD2cysteine-rich with EGF-like domains 20.503
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.477
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.416
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.257
SDF2L1stromal cell-derived factor 2-like 10.170
HYOU1hypoxia up-regulated 10.085
FN1fibronectin 10.050
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.043
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.038
TGFB3transforming growth factor, beta 30.036
GLIS2GLIS family zinc finger 20.027
PDIA4protein disulfide isomerase family A, member 40.025
C1QTNF1C1q and tumor necrosis factor related protein 10.024
GLAgalactosidase, alpha0.021
HSPB1heat shock 27kDa protein 10.018
DNAJB11DnaJ (Hsp40) homolog, subfamily B, member 110.018
GMPPBGDP-mannose pyrophosphorylase B0.017
ACVRL1activin A receptor type II-like 10.015
ARF3ADP-ribosylation factor 30.013
FSTL1follistatin-like 10.013
HSP90B1heat shock protein 90kDa beta (Grp94), member 10.013
TGFBR1transforming growth factor, beta receptor 10.013
NRP1neuropilin 10.011
PDIA6protein disulfide isomerase family A, member 60.011
ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)0.011
CDK2AP2cyclin-dependent kinase 2 associated protein 20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc12a1solute carrier family 12, member 10.717
Chrna3cholinergic receptor, nicotinic, alpha polypeptide 30.703
Chrnb4cholinergic receptor, nicotinic, beta polypeptide 40.340
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.239
Wnk4WNK lysine deficient protein kinase 40.209
Agtr1aangiotensin II receptor, type 1a0.193
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.165
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.138
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.130
Ren1renin 1 structural0.124
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.123
Keg1kidney expressed gene 10.107
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.105
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.100
CrpC-reactive protein, pentraxin-related0.091
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.081
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.079
Cps1carbamoyl-phosphate synthetase 10.078
Cyp2c39cytochrome P450, family 2, subfamily c, polypeptide 390.060
Upp2uridine phosphorylase 20.058
Otcornithine transcarbamylase0.055
Apoc4apolipoprotein C-IV0.054
Akr1c6aldo-keto reductase family 1, member C60.050
Apohapolipoprotein H0.044
Tgfb1transforming growth factor, beta 10.044
Hsd3b2hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 20.042
Cml2camello-like 20.040
Slc27a5solute carrier family 27 (fatty acid transporter), member 50.038
Cyp2f2cytochrome P450, family 2, subfamily f, polypeptide 20.036
Mup5major urinary protein 50.033
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.033
Ssr2signal sequence receptor, beta0.031
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.031
G6pcglucose-6-phosphatase, catalytic0.031
Prlrprolactin receptor0.030
Creld2cysteine-rich with EGF-like domains 20.030
Drd2dopamine receptor D20.030
Cyp3a11cytochrome P450, family 3, subfamily a, polypeptide 110.029
Serpind1serine (or cysteine) peptidase inhibitor, clade D, member 10.028
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.028
F9coagulation factor IX0.028
Leprleptin receptor0.028
Grid1glutamate receptor, ionotropic, delta 10.028
Spry4sprouty homolog 4 (Drosophila)0.027
Cyp2d9cytochrome P450, family 2, subfamily d, polypeptide 90.026
Nr1i2nuclear receptor subfamily 1, group I, member 20.025
Hamphepcidin antimicrobial peptide0.025
Lect2leukocyte cell-derived chemotaxin 20.024
Hchemolytic complement0.023
Ghgrowth hormone0.022
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.022
Lpar5lysophosphatidic acid receptor 50.022
Vdrvitamin D receptor0.022
Hrghistidine-rich glycoprotein0.021
Cyp2c54cytochrome P450, family 2, subfamily c, polypeptide 540.021
Slc6a2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.021
Acvrl1activin A receptor, type II-like 10.021
Azgp1alpha-2-glycoprotein 1, zinc0.021
Tdo2tryptophan 2,3-dioxygenase0.021
Dmgdhdimethylglycine dehydrogenase precursor0.021
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.020
Serpina1bserine (or cysteine) preptidase inhibitor, clade A, member 1B0.020
Cyp2b10cytochrome P450, family 2, subfamily b, polypeptide 100.020
Mup4major urinary protein 40.019
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.019
Npy1rneuropeptide Y receptor Y10.018
Adrb3adrenergic receptor, beta 30.018
S100a5S100 calcium binding protein A50.018
Cyp2b13cytochrome P450, family 2, subfamily b, polypeptide 130.018
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.017
Glis2GLIS family zinc finger 20.016
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.016
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.016
Mup3major urinary protein 30.016
Apoa5apolipoprotein A-V0.016
Gpr12G-protein coupled receptor 120.016
Hmgcs23-hydroxy-3-methylglutaryl-Coenzyme A synthase 20.016
Pdia6protein disulfide isomerase associated 60.015
Ugt2a3UDP glucuronosyltransferase 2 family, polypeptide A30.015
Serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.015
Rdh7retinol dehydrogenase 70.015
Cyp2j5cytochrome P450, family 2, subfamily j, polypeptide 50.015
Hsd3b3hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 30.015
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.014
Cfhr1complement factor H-related 10.014
Acsm2acyl-CoA synthetase medium-chain family member 20.014
Cyp11b1cytochrome P450, family 11, subfamily b, polypeptide 10.014
Vav2vav 2 oncogene0.014
Ucp3uncoupling protein 3 (mitochondrial, proton carrier)0.014
C730048C13RikRIKEN cDNA C730048C13 gene0.014
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.013
Ugt3a2UDP glycosyltransferases 3 family, polypeptide A20.013
Serpina3mserine (or cysteine) peptidase inhibitor, clade A, member 3M0.013
Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide0.013
Htr5a5-hydroxytryptamine (serotonin) receptor 5A0.013
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.013
Krtap6-1keratin associated protein 6-10.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism