The network for 'positive regulation of mitosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of mitosis

Any process that activates or increases the frequency, rate or extent of mitosis.

NameDescriptionProbabilityFunc Analog Organism
CDC27cell division cycle 27 homolog (S. cerevisiae)0.999
CDC20cell division cycle 20 homolog (S. cerevisiae)0.998
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.993
ANAPC4anaphase promoting complex subunit 40.981
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.787
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.718
PLK1polo-like kinase 10.701
EGFRepidermal growth factor receptor0.689
IL1R1interleukin 1 receptor, type I0.683
CAV1caveolin 1, caveolae protein, 22kDa0.640
PTPN1protein tyrosine phosphatase, non-receptor type 10.631
JAK2Janus kinase 20.575
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.467
CD80CD80 molecule0.435
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.429
ANAPC7anaphase promoting complex subunit 70.420
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.419
GRAP2GRB2-related adaptor protein 20.399
PTTG1pituitary tumor-transforming 10.392
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.322
CCNA2cyclin A20.320
ANAPC1anaphase promoting complex subunit 10.289
SMC6structural maintenance of chromosomes 60.277
NRP1neuropilin 10.219
NSMCE1non-SMC element 1 homolog (S. cerevisiae)0.204
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.188
CD86CD86 molecule0.183
INCENPinner centromere protein antigens 135/155kDa0.181
IRS1insulin receptor substrate 10.177
E2F1E2F transcription factor 10.175
CDC26cell division cycle 26 homolog (S. cerevisiae)0.150
CDC23cell division cycle 23 homolog (S. cerevisiae)0.143
MBNL1muscleblind-like (Drosophila)0.135
ENGendoglin0.126
HNRNPH1heterogeneous nuclear ribonucleoprotein H1 (H)0.123
AURKBaurora kinase B0.118
CCNB1cyclin B10.117
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.114
ANAPC11anaphase promoting complex subunit 110.110
PRRC2Cproline-rich coiled-coil 2C0.107
PPIGpeptidylprolyl isomerase G (cyclophilin G)0.099
RB1retinoblastoma 10.097
IL1RAPinterleukin 1 receptor accessory protein0.092
PDGFAplatelet-derived growth factor alpha polypeptide0.090
E2F4E2F transcription factor 4, p107/p130-binding0.089
IGF2Rinsulin-like growth factor 2 receptor0.085
PGFplacental growth factor0.081
GRB10growth factor receptor-bound protein 100.080
FUBP1far upstream element (FUSE) binding protein 10.071
DKK1dickkopf homolog 1 (Xenopus laevis)0.068
ITGB1BP3integrin beta 1 binding protein 30.065
MYBL2v-myb myeloblastosis viral oncogene homolog (avian)-like 20.064
NR4A1nuclear receptor subfamily 4, group A, member 10.064
UBE2Cubiquitin-conjugating enzyme E2C0.063
ANAPC5anaphase promoting complex subunit 50.061
SMC3structural maintenance of chromosomes 30.060
INSRinsulin receptor0.060
PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.059
TROAPtrophinin associated protein (tastin)0.058
CENPFcentromere protein F, 350/400kDa (mitosin)0.058
NEK2NIMA (never in mitosis gene a)-related kinase 20.058
AXIN1axin 10.057
MIS18BP1MIS18 binding protein 10.056
RBL1retinoblastoma-like 1 (p107)0.056
CCNB2cyclin B20.055
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.055
TINF2TERF1 (TRF1)-interacting nuclear factor 20.054
GSK3Bglycogen synthase kinase 3 beta0.053
PTENphosphatase and tensin homolog0.052
RBL2retinoblastoma-like 2 (p130)0.051
THBS1thrombospondin 10.051
SIRT2sirtuin 20.051
CLSPNclaspin0.050
THOC2THO complex 20.050
TPRtranslocated promoter region (to activated MET oncogene)0.049
GTSE1G-2 and S-phase expressed 10.047
DCNdecorin0.047
DEAF1deformed epidermal autoregulatory factor 1 (Drosophila)0.045
TGFAtransforming growth factor, alpha0.045
KIF20Akinesin family member 20A0.044
CDKN3cyclin-dependent kinase inhibitor 30.044
TERF2IPtelomeric repeat binding factor 2, interacting protein0.044
CDC25Ccell division cycle 25 homolog C (S. pombe)0.042
IL1RNinterleukin 1 receptor antagonist0.041
TTKTTK protein kinase0.041
PRNPprion protein0.041
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.040
APPamyloid beta (A4) precursor protein0.040
CDC16cell division cycle 16 homolog (S. cerevisiae)0.040
CDK2cyclin-dependent kinase 20.039
CKAP2Lcytoskeleton associated protein 2-like0.038
E2F5E2F transcription factor 5, p130-binding0.037
RBBP8retinoblastoma binding protein 80.036
PTPRJprotein tyrosine phosphatase, receptor type, J0.036
PSRC1proline/serine-rich coiled-coil 10.036
VEGFAvascular endothelial growth factor A0.035
FAM64Afamily with sequence similarity 64, member A0.033
GAS2L3growth arrest-specific 2 like 30.031
LIN54lin-54 homolog (C. elegans)0.031
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.031
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.976
Col1a1collagen, type I, alpha 10.823
Shhsonic hedgehog0.680
Grb10growth factor receptor bound protein 100.510
Nos3nitric oxide synthase 3, endothelial cell0.333
Neurod1neurogenic differentiation 10.320
Ctnnb1catenin (cadherin associated protein), beta 10.308
Ascl1achaete-scute complex homolog 1 (Drosophila)0.283
Ccnb1cyclin B10.260
Csf1colony stimulating factor 1 (macrophage)0.242
Cdk1cyclin-dependent kinase 10.212
Tgfb1transforming growth factor, beta 10.204
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.202
Ccnb2cyclin B20.202
Apcadenomatosis polyposis coli0.185
Ptenphosphatase and tensin homolog0.175
Ube2cubiquitin-conjugating enzyme E2C0.160
Neurod4neurogenic differentiation 40.131
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.125
H2afxH2A histone family, member X0.125
Pax6paired box gene 60.118
Meox2mesenchyme homeobox 20.116
Axin1axin 10.114
Ckap2cytoskeleton associated protein 20.107
Ccna2cyclin A20.106
Kdrkinase insert domain protein receptor0.105
CblCasitas B-lineage lymphoma0.105
Neurog2neurogenin 20.102
Pthlhparathyroid hormone-like peptide0.099
Fgfr3fibroblast growth factor receptor 30.092
Vegfavascular endothelial growth factor A0.091
Plk1polo-like kinase 1 (Drosophila)0.090
Runx2runt related transcription factor 20.090
Lyz2lysozyme 20.088
Ghrgrowth hormone receptor0.086
Prf1perforin 1 (pore forming protein)0.084
Pkd1polycystic kidney disease 1 homolog0.078
Lrp6low density lipoprotein receptor-related protein 60.077
En2engrailed 20.077
Pax3paired box gene 30.072
Otx2orthodenticle homolog 2 (Drosophila)0.070
Fgfr2fibroblast growth factor receptor 20.068
Prc1protein regulator of cytokinesis 10.064
Kif20akinesin family member 20A0.063
Cd19CD19 antigen0.062
Il6stinterleukin 6 signal transducer0.061
Notch2Notch gene homolog 2 (Drosophila)0.059
Hand2heart and neural crest derivatives expressed transcript 20.058
Tcf3transcription factor 30.058
Gab1growth factor receptor bound protein 2-associated protein 10.054
Notch1Notch gene homolog 1 (Drosophila)0.053
Kif22kinesin family member 220.053
Neurog3neurogenin 30.051
Bmp4bone morphogenetic protein 40.050
Cdca8cell division cycle associated 80.050
Ptpn11protein tyrosine phosphatase, non-receptor type 110.048
Kitlkit ligand0.045
Gli3GLI-Kruppel family member GLI30.045
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.043
Cdkn2acyclin-dependent kinase inhibitor 2A0.043
Cdh5cadherin 50.041
Flt4FMS-like tyrosine kinase 40.039
MecomMDS1 and EVI1 complex locus0.039
Cdc25ccell division cycle 25 homolog C (S. pombe)0.038
Fbn1fibrillin 10.037
Cdkn1bcyclin-dependent kinase inhibitor 1B0.036
Tgfbr2transforming growth factor, beta receptor II0.036
Rag2recombination activating gene 20.036
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.035
En1engrailed 10.035
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.034
Hoxa10homeobox A100.033
Mxd3Max dimerization protein 30.032
Rag1recombination activating gene 10.032
Cbfa2t3core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)0.032
Fam64afamily with sequence similarity 64, member A0.032
Onecut1one cut domain, family member 10.032
Egfrepidermal growth factor receptor0.031
Foxc2forkhead box C20.031
Kiss1KiSS-1 metastasis-suppressor0.031
Aurkbaurora kinase B0.031
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.030
Myf5myogenic factor 50.030
Hmmrhyaluronan mediated motility receptor (RHAMM)0.030
Kitkit oncogene0.029
Spag5sperm associated antigen 50.028
Itgb1integrin beta 1 (fibronectin receptor beta)0.028
Tgfb2transforming growth factor, beta 20.027
Pdx1pancreatic and duodenal homeobox 10.027
Mki67antigen identified by monoclonal antibody Ki 670.027
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.027
Socs1suppressor of cytokine signaling 10.027
Il6interleukin 60.027
Foxc1forkhead box C10.026
Rb1retinoblastoma 10.026
Tbx3T-box 30.026
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.026
Twist2twist homolog 2 (Drosophila)0.026
Ccnfcyclin F0.025
Npr3natriuretic peptide receptor 30.025
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CDC20Cdc20p0.041
CDC16Cdc16p0.039
CDC23Cdc23p0.033
NSE4Nse4p0.032
MMS21Mms21p0.031
CDC26Cdc26p0.021
CDC27Cdc27p0.015
CLB1Clb1p0.014