The network for 'glucan biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glucan biosynthetic process

The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.

NameDescriptionProbabilityFunc Analog Organism
INSRinsulin receptor1.000
GRB10growth factor receptor-bound protein 100.991
IRS2insulin receptor substrate 20.954
IRS1insulin receptor substrate 10.911
IGF1Rinsulin-like growth factor 1 receptor0.888
PTPN1protein tyrosine phosphatase, non-receptor type 10.550
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.482
DYRK1Bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B0.415
DCAF7DDB1 and CUL4 associated factor 70.312
NOXA1NADPH oxidase activator 10.256
PRKCZprotein kinase C, zeta0.252
PRKCBprotein kinase C, beta0.251
CDC37cell division cycle 37 homolog (S. cerevisiae)0.133
STAT5Bsignal transducer and activator of transcription 5B0.131
MDM2Mdm2 p53 binding protein homolog (mouse)0.119
IGF2Rinsulin-like growth factor 2 receptor0.114
GYS1glycogen synthase 1 (muscle)0.109
AGLamylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase0.102
SH2B1SH2B adaptor protein 10.074
DYRK4dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 40.070
PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.067
DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 20.063
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.060
SHC1SHC (Src homology 2 domain containing) transforming protein 10.056
ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 10.052
NCF1neutrophil cytosolic factor 10.044
GYG2glycogenin 20.043
PKM2pyruvate kinase, muscle0.041
HIPK2homeodomain interacting protein kinase 20.040
GYG1glycogenin 10.036
RAB6ARAB6A, member RAS oncogene family0.034
PICK1protein interacting with PRKCA 10.034
LDHAlactate dehydrogenase A0.033
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide0.031
SH3RF1SH3 domain containing ring finger 10.030
RAB1ARAB1A, member RAS oncogene family0.028
BCL2B-cell CLL/lymphoma 20.027
LZTS2leucine zipper, putative tumor suppressor 20.026
PPP1CCprotein phosphatase 1, catalytic subunit, gamma isozyme0.025
PRKCAprotein kinase C, alpha0.023
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.022
ARF4ADP-ribosylation factor 40.022
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.021
CCL14chemokine (C-C motif) ligand 140.021
ALDOAaldolase A, fructose-bisphosphate0.021
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.021
FAF1Fas (TNFRSF6) associated factor 10.021
OSBPoxysterol binding protein0.021
KAT2BK(lysine) acetyltransferase 2B0.020
DCTN1dynactin 10.020
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.019
SYKspleen tyrosine kinase0.019
GCKRglucokinase (hexokinase 4) regulator0.019
SEC24ASEC24 family, member A (S. cerevisiae)0.019
PILRApaired immunoglobin-like type 2 receptor alpha0.018
SCP2sterol carrier protein 20.018
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 10.018
EPM2Aepilepsy, progressive myoclonus type 2A, Lafora disease (laforin)0.017
S100A2S100 calcium binding protein A20.017
TSC22D1TSC22 domain family, member 10.017
APPL1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.016
RAB14RAB14, member RAS oncogene family0.015
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.015
GRB14growth factor receptor-bound protein 140.015
MAP3K1mitogen-activated protein kinase kinase kinase 10.015
PTPN6protein tyrosine phosphatase, non-receptor type 60.015
RAB8ARAB8A, member RAS oncogene family0.014
SESN2sestrin 20.014
CSKc-src tyrosine kinase0.014
PDPK13-phosphoinositide dependent protein kinase-10.014
RPL11ribosomal protein L110.013
GYS2glycogen synthase 2 (liver)0.013
ENPP5ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)0.013
PPIDpeptidylprolyl isomerase D0.013
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 20.013
GBASglioblastoma amplified sequence0.012
CCND1cyclin D10.012
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.012
CCDC115coiled-coil domain containing 1150.012
PREX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 10.011
SPRED1sprouty-related, EVH1 domain containing 10.011
SETDB1SET domain, bifurcated 10.011
BADBCL2-associated agonist of cell death0.011
VHLvon Hippel-Lindau tumor suppressor0.011
BCKDKbranched chain ketoacid dehydrogenase kinase0.011
FOXO1forkhead box O10.011
TRIM9tripartite motif containing 90.011
NTRK1neurotrophic tyrosine kinase, receptor, type 10.011
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.011
MDM4Mdm4 p53 binding protein homolog (mouse)0.011
CYBAcytochrome b-245, alpha polypeptide0.010
CUX1cut-like homeobox 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG5362CG5362 gene product from transcript CG5362-RA0.227
ThiolaseCG4581 gene product from transcript CG4581-RA0.048
EcREcdysone receptor0.045
Akt1CG4006 gene product from transcript CG4006-RA0.039
PgkPhosphoglycerate kinase0.038
S6kRPS6-p70-protein kinase0.033
ThorCG8846 gene product from transcript CG8846-RA0.029
InRInsulin-like receptor0.026
ZwZwischenferment0.024
IdhIsocitrate dehydrogenase0.020
PgiPhosphoglucose isomerase0.019
foxoforkhead box, sub-group O0.018
CkIalphaCasein kinase Ialpha0.016
Got2Glutamate oxaloacetate transaminase 20.016
Gs1Glutamine synthetase 10.015
CycGCyclin G0.014
PgdPhosphogluconate dehydrogenase0.014
HcfHost cell factor0.014
TpiTriose phosphate isomerase0.014
dmdiminutive0.013
Pi3K92ECG4141 gene product from transcript CG4141-RB0.013
MenMalic enzyme0.012
myoglianinCG1838 gene product from transcript CG1838-RD0.011
CG6904CG6904 gene product from transcript CG6904-RC0.011
PyKPyruvate kinase0.011
bskbasket0.011
SxlSex lethal0.010
GipGIP-like0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Insrinsulin receptor0.975
Rargretinoic acid receptor, gamma0.808
Irs2insulin receptor substrate 20.743
Cry2cryptochrome 2 (photolyase-like)0.691
Per1period homolog 1 (Drosophila)0.605
Leprleptin receptor0.554
Ghrgrowth hormone receptor0.506
Grb10growth factor receptor bound protein 100.390
Igf1rinsulin-like growth factor I receptor0.369
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.303
Tefthyrotroph embryonic factor0.295
Rararetinoic acid receptor, alpha0.260
Arntlaryl hydrocarbon receptor nuclear translocator-like0.259
Per2period homolog 2 (Drosophila)0.257
Pim3proviral integration site 30.142
DbpD site albumin promoter binding protein0.136
Rxraretinoid X receptor alpha0.099
Akt1thymoma viral proto-oncogene 10.088
Igf2rinsulin-like growth factor 2 receptor0.082
Pax2paired box gene 20.077
Ednraendothelin receptor type A0.076
Usp2ubiquitin specific peptidase 20.074
Tenc1tensin like C1 domain-containing phosphatase0.072
Klf9Kruppel-like factor 90.069
Pim2proviral integration site 20.061
Skp1aS-phase kinase-associated protein 1A0.060
Pnpla2patatin-like phospholipase domain containing 20.059
Prkab1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.057
Rarbretinoic acid receptor, beta0.054
Thrathyroid hormone receptor alpha0.052
Igf2insulin-like growth factor 20.048
Akt2thymoma viral proto-oncogene 20.046
Lhx3LIM homeobox protein 30.045
Ins2insulin II0.044
Irs1insulin receptor substrate 10.040
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.038
Csnk1ecasein kinase 1, epsilon0.037
Btrcbeta-transducin repeat containing protein0.036
Hoxa3homeobox A30.033
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.033
Cdkn1ccyclin-dependent kinase inhibitor 1C (P57)0.030
Ece1endothelin converting enzyme 10.029
BmperBMP-binding endothelial regulator0.029
Lipelipase, hormone sensitive0.028
Hoxb3homeobox B30.025
Thrbthyroid hormone receptor beta0.025
Capn1calpain 10.023
Mknk2MAP kinase-interacting serine/threonine kinase 20.022
Tpothyroid peroxidase0.021
Sim1single-minded homolog 1 (Drosophila)0.021
Eya1eyes absent 1 homolog (Drosophila)0.021
Lpin1lipin 10.021
Pax8paired box gene 80.020
Cdkn1bcyclin-dependent kinase inhibitor 1B0.020
Rps2ribosomal protein S20.019
Rps3ribosomal protein S30.019
Vapavesicle-associated membrane protein, associated protein A0.019
Nficnuclear factor I/C0.018
Chrdchordin0.018
Ctdsp2CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 20.018
Per3period homolog 3 (Drosophila)0.018
Cav1caveolin 1, caveolae protein0.017
Slc27a1solute carrier family 27 (fatty acid transporter), member 10.017
Arandrogen receptor0.017
Prkaa1protein kinase, AMP-activated, alpha 1 catalytic subunit0.017
Clockcircadian locomotor output cycles kaput0.017
Pim1proviral integration site 10.016
Itga1integrin alpha 10.016
Car11carbonic anhydrase 110.016
Stat5asignal transducer and activator of transcription 5A0.016
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.015
Tff1trefoil factor 10.015
Ppargperoxisome proliferator activated receptor gamma0.015
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.015
RoraRAR-related orphan receptor alpha0.015
Tgfbr3transforming growth factor, beta receptor III0.014
Hnrnph2heterogeneous nuclear ribonucleoprotein H20.014
Fgfr1fibroblast growth factor receptor 10.014
2310035K24RikRIKEN cDNA 2310035K24 gene0.014
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.014
Inppl1inositol polyphosphate phosphatase-like 10.014
Nedd4neural precursor cell expressed, developmentally down-regulated 40.014
Galr3galanin receptor 30.014
Nr1h4nuclear receptor subfamily 1, group H, member 40.014
Slc11a2solute carrier family 11 (proton-coupled divalent metal ion transporters), member 20.013
Htr3a5-hydroxytryptamine (serotonin) receptor 3A0.013
Inhbcinhibin beta-C0.013
Cideacell death-inducing DNA fragmentation factor, alpha subunit-like effector A0.013
Spnb1spectrin beta 10.013
D19Wsu162eDNA segment, Chr 19, Wayne State University 162, expressed0.013
Klklotho0.013
Klhl9kelch-like 9 (Drosophila)0.013
Phf1PHD finger protein 10.013
Phyhphytanoyl-CoA hydroxylase0.013
Socs1suppressor of cytokine signaling 10.012
Txnipthioredoxin interacting protein0.012
Klf12Kruppel-like factor 120.012
Osr1odd-skipped related 1 (Drosophila)0.012
Drd2dopamine receptor D20.012
Fbxo11F-box protein 110.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Serinc1serine incorporator 10.297
DbpD site of albumin promoter (albumin D-box) binding protein0.185
Snrpbsmall nuclear ribonucleoprotein polypeptides B and B10.152
Pgm1phosphoglucomutase 10.106
Rab1bRAB1B, member RAS oncogene family0.084
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.076
Eef2eukaryotic translation elongation factor 20.070
Nr1d2nuclear receptor subfamily 1, group D, member 20.069
Etfdhelectron-transferring-flavoprotein dehydrogenase0.065
Ugp2UDP-glucose pyrophosphorylase 20.058
Sypl1synaptophysin-like 10.053
Gpiglucose phosphate isomerase0.049
Gna12guanine nucleotide binding protein (G protein) alpha 120.049
Ptp4a1protein tyrosine phosphatase type IVA, member 10.048
Pygmphosphorylase, glycogen, muscle0.044
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.041
Acyp2acylphosphatase 2, muscle type0.038
Syngr2synaptogyrin 20.036
Pfn1profilin 10.034
Pkm2pyruvate kinase, muscle0.032
Irs1insulin receptor substrate 10.028
Nup153nucleoporin 1530.027
Ccnd3cyclin D30.027
Csnk1g2casein kinase 1, gamma 20.027
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.026
Timp3TIMP metallopeptidase inhibitor 30.024
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.024
Aldoaaldolase A, fructose-bisphosphate0.023
Ube2v2ubiquitin-conjugating enzyme E2 variant 20.023
Pik3r2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.022
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.022
Vdac1voltage-dependent anion channel 10.021
Oaz1ornithine decarboxylase antizyme 10.021
Gps1G protein pathway suppressor 10.021
Usf2upstream transcription factor 2, c-fos interacting0.021
Fez2fasciculation and elongation protein zeta 2 (zygin II)0.021
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.021
Acox1acyl-Coenzyme A oxidase 1, palmitoyl0.020
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.020
Slc26a2solute carrier family 26 (sulfate transporter), member 20.019
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.018
LOC100362155cysteine and histidine rich 10.018
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.018
Decr12,4-dienoyl CoA reductase 1, mitochondrial0.018
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.017
Rps8ribosomal protein S80.017
Hibadh3-hydroxyisobutyrate dehydrogenase0.017
Akr1a1aldo-keto reductase family 1, member A1 (aldehyde reductase)0.017
Tefthyrotrophic embryonic factor0.016
Lama2laminin, alpha 20.016
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.015
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.015
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.015
Acvr1activin A receptor, type I0.015
Cyfip2cytoplasmic FMR1 interacting protein 20.014
Smad7SMAD family member 70.014
Txnl1thioredoxin-like 10.014
Gja1gap junction protein, alpha 10.014
Mug1murinoglobulin 10.014
Sgk2serum/glucocorticoid regulated kinase 20.014
Akap1A kinase (PRKA) anchor protein 10.014
Phka1phosphorylase kinase, alpha 10.013
Ndrg2N-myc downstream regulated gene 20.013
Pfkmphosphofructokinase, muscle0.013
Gria2glutamate receptor, ionotropic, AMPA 20.013
Clcn4-2chloride channel 4-20.013
Cdk4cyclin-dependent kinase 40.013
Ldlrlow density lipoprotein receptor0.012
Eif3feukaryotic translation initiation factor 3, subunit F0.012
Ak1adenylate kinase 10.012
Nf1neurofibromin 10.012
Dcun1d5DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)0.012
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.011
Chordc1cysteine and histidine-rich domain (CHORD)-containing 10.011
Pik3r1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.011
Ldhblactate dehydrogenase B0.011
Metmet proto-oncogene0.011
Sgtasmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha0.011
Me1malic enzyme 1, NADP(+)-dependent, cytosolic0.011
Pdk2pyruvate dehydrogenase kinase, isozyme 20.011
Guca2aguanylate cyclase activator 2a (guanylin)0.011
Nntnicotinamide nucleotide transhydrogenase0.011
Acacaacetyl-coenzyme A carboxylase alpha0.011
Egln3EGL nine homolog 3 (C. elegans)0.011
Ptk2bPTK2B protein tyrosine kinase 2 beta0.010
Fgfr1Fibroblast growth factor receptor 10.010
Zfp364zinc finger protein 3640.010
Vldlrvery low density lipoprotein receptor0.010
Hist1h1ahistone cluster 1, H1a0.010
Ascl1achaete-scute complex homolog 1 (Drosophila)0.010
Ddx39DEAD (Asp-Glu-Ala-Asp) box polypeptide 390.010
Orm1orosomucoid 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
GSY2Gsy2p1.000
GSY1Gsy1p0.999
GLG2Glg2p0.995
GPH1Gph1p0.950
PIG2Pig2p0.887
GIP2Gip2p0.884
UGP1Ugp1p0.853
GLG1Glg1p0.804
RHO1Rho1p0.610
HXK1Hxk1p0.609
PSK1Psk1p0.582
MKK1Mkk1p0.397
GLC7Glc7p0.372
PCL10Pcl10p0.347
GAC1Gac1p0.264
GDB1Gdb1p0.263
PHO85Pho85p0.207
PCL8Pcl8p0.197
MMR1Mmr1p0.194
MYO5Myo5p0.140
HOC1Hoc1p0.139
CAK1Cak1p0.119
RDI1Rdi1p0.107
KRE6Kre6p0.102
YGR071Chypothetical protein0.098
PKC1Pkc1p0.098
EMI2Emi2p0.095
ROM2Rom2p0.091
RGC1Rgc1p0.089
BBC1Bbc1p0.070
YNR014Whypothetical protein0.069
BEM2Bem2p0.068
CBK1Cbk1p0.067
MPT5Mpt5p0.064
YCL042Whypothetical protein0.062
YGR205Whypothetical protein0.058
HKR1Hkr1p0.052
BDH2Bdh2p0.052
PSK2Psk2p0.052
RGI1Rgi1p0.048
PTP3Ptp3p0.046
MER1Mer1p0.045
PHO81Pho81p0.045
CDC42Cdc42p0.043
ACK1Ack1p0.043
FMP48Fmp48p0.041
MAL32Mal32p0.039
YIL151Chypothetical protein0.037
GLK1Glk1p0.037
YGL010Whypothetical protein0.036
YNL144Chypothetical protein0.036
LSP1Lsp1p0.036
FYV8Fyv8p0.035
SGE1Sge1p0.035
PCL2Pcl2p0.035
DCW1Dcw1p0.034
TOS1Tos1p0.034
SIA1Sia1p0.032
KEL1Kel1p0.031
PGM2Pgm2p0.031
PGM1Pgm1p0.031
GLN1Gln1p0.031
SRD1Srd1p0.031
TAM41Tam41p0.031
RMD5Rmd5p0.030
YLR162Whypothetical protein0.030
YJL181Whypothetical protein0.030
YLR264C-Ahypothetical protein0.030
MBR1Mbr1p0.030
LEU2Leu2p0.029
YGL242Chypothetical protein0.029
EAR1Ear1p0.029
PYK2Pyk2p0.028
YOL038C-Ahypothetical protein0.028
CCH1Cch1p0.027
GIC2Gic2p0.027
SUC2Suc2p0.027
YLR177Whypothetical protein0.027
ICS2Ics2p0.027
HEM15Hem15p0.027
MRK1Mrk1p0.026
SSP1Ssp1p0.026
SAC7Sac7p0.026
CLG1Clg1p0.025
HRR25Hrr25p0.025
COX5BCox5bp0.025
FKS1Fks1p0.024
CLN3Cln3p0.023
NGL3Ngl3p0.023
PNS1Pns1p0.023
CHS1Chs1p0.023
TRR1Trr1p0.023
YNL058Chypothetical protein0.023
YJR115Whypothetical protein0.023
SSK1Ssk1p0.023
PCL9Pcl9p0.023
ICY1Icy1p0.023
OCH1Och1p0.022
VHS1Vhs1p0.022
YNR064Chypothetical protein0.022