The network for 'mitochondrial respiratory chain complex i biogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mitochondrial respiratory chain complex i biogenesis

The biogenesis of a mitochondrial respiratory chain complex I, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.

NameDescriptionProbabilityFunc Analog Organism
NDUFS7NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)0.999
NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)0.854
NDUFV1NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa0.828
NDUFA2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa0.815
NDUFS2NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)0.630
ICT1immature colon carcinoma transcript 10.624
NDUFS8NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)0.542
CYC1cytochrome c-10.409
NDUFA7NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa0.339
NDUFV2NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa0.275
EIF2B3eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa0.150
CHCHD4coiled-coil-helix-coiled-coil-helix domain containing 40.149
MRPL15mitochondrial ribosomal protein L150.133
NDUFAF3NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 30.128
IDH3Aisocitrate dehydrogenase 3 (NAD+) alpha0.105
RTN4IP1reticulon 4 interacting protein 10.103
NDUFA9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa0.102
SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.076
MRPL35mitochondrial ribosomal protein L350.075
NDUFB8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa0.072
DCXRdicarbonyl/L-xylulose reductase0.069
COQ9coenzyme Q9 homolog (S. cerevisiae)0.067
COQ3coenzyme Q3 homolog, methyltransferase (S. cerevisiae)0.065
NDUFB7NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa0.061
GFM1G elongation factor, mitochondrial 10.059
DNAJA3DnaJ (Hsp40) homolog, subfamily A, member 30.055
GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.050
SCO1SCO cytochrome oxidase deficient homolog 1 (yeast)0.045
ECI1enoyl-CoA delta isomerase 10.044
C20orf7chromosome 20 open reading frame 70.042
MRPL34mitochondrial ribosomal protein L340.042
LYRM7Lyrm7 homolog (mouse)0.039
YIF1AYip1 interacting factor homolog A (S. cerevisiae)0.037
SAMM50sorting and assembly machinery component 50 homolog (S. cerevisiae)0.035
APOOapolipoprotein O0.035
NDUFS6NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)0.035
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.034
C3orf1chromosome 3 open reading frame 10.034
CYCScytochrome c, somatic0.032
SFXN4sideroflexin 40.029
MRPS11mitochondrial ribosomal protein S110.029
NDUFAF1NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 10.028
MRPL32mitochondrial ribosomal protein L320.028
MECRmitochondrial trans-2-enoyl-CoA reductase0.028
TSFMTs translation elongation factor, mitochondrial0.026
MIPEPmitochondrial intermediate peptidase0.025
C4orf14chromosome 4 open reading frame 140.025
SURF1surfeit 10.025
HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit0.024
MGST3microsomal glutathione S-transferase 30.023
OXNAD1oxidoreductase NAD-binding domain containing 10.023
HIGD2AHIG1 hypoxia inducible domain family, member 2A0.023
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.023
MRPL46mitochondrial ribosomal protein L460.023
NDUFA8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa0.022
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.022
UQCRC2ubiquinol-cytochrome c reductase core protein II0.022
NFS1NFS1 nitrogen fixation 1 homolog (S. cerevisiae)0.022
EIF2B4eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa0.021
MRPL16mitochondrial ribosomal protein L160.020
AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)0.020
MRPL10mitochondrial ribosomal protein L100.020
PCCBpropionyl CoA carboxylase, beta polypeptide0.019
NSUN5NOP2/Sun domain family, member 50.018
PDHBpyruvate dehydrogenase (lipoamide) beta0.017
MRPL23mitochondrial ribosomal protein L230.017
KAT2AK(lysine) acetyltransferase 2A0.016
PDHA1pyruvate dehydrogenase (lipoamide) alpha 10.015
TMEM70transmembrane protein 700.015
TMEM126Atransmembrane protein 126A0.015
MRPL30mitochondrial ribosomal protein L300.015
ATP5HATP synthase, H+ transporting, mitochondrial Fo complex, subunit d0.015
MRRFmitochondrial ribosome recycling factor0.015
WDR92WD repeat domain 920.015
FAHD1fumarylacetoacetate hydrolase domain containing 10.014
IDH3Gisocitrate dehydrogenase 3 (NAD+) gamma0.014
MDH2malate dehydrogenase 2, NAD (mitochondrial)0.014
C6orf203chromosome 6 open reading frame 2030.014
SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.013
NDUFB9NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa0.013
COX11COX11 cytochrome c oxidase assembly homolog (yeast)0.013
APEHN-acylaminoacyl-peptide hydrolase0.013
C19orf56chromosome 19 open reading frame 560.013
ERCC1excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)0.012
C8orf38chromosome 8 open reading frame 380.012
C18orf19chromosome 18 open reading frame 190.012
GPX1glutathione peroxidase 10.012
ARL2ADP-ribosylation factor-like 20.012
MRPS9mitochondrial ribosomal protein S90.012
LIASlipoic acid synthetase0.012
ISOC1isochorismatase domain containing 10.011
PET112LPET112-like (yeast)0.011
MRPL24mitochondrial ribosomal protein L240.011
PREBprolactin regulatory element binding0.011
METTL17methyltransferase like 170.011
MRPS7mitochondrial ribosomal protein S70.011
MRPL1mitochondrial ribosomal protein L10.010
TMEM186transmembrane protein 1860.010
SELRC1Sel1 repeat containing 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG1970CG1970 gene product from transcript CG1970-RA0.072
CG3214CG3214 gene product from transcript CG3214-RB0.028
CG7712CG7712 gene product from transcript CG7712-RA0.015
PdswCG8844 gene product from transcript CG8844-RA0.012
CG3192CG3192 gene product from transcript CG3192-RA0.011
CG7603CG7603 gene product from transcript CG7603-RA0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism