The network for 'regulation of axon extension involved in axon guidance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of axon extension involved in axon guidance

Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.

NameDescriptionProbabilityFunc Analog Organism
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 301.000
NRP1neuropilin 11.000
FGFR1fibroblast growth factor receptor 11.000
VEGFAvascular endothelial growth factor A1.000
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.999
FGFR2fibroblast growth factor receptor 20.996
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.989
RING1ring finger protein 10.962
CBX8chromobox homolog 80.935
RNF2ring finger protein 20.905
PGFplacental growth factor0.865
PLCG1phospholipase C, gamma 10.856
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.850
PPP2R5Dprotein phosphatase 2, regulatory subunit B', delta0.810
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.808
CBX6chromobox homolog 60.804
SORBS1sorbin and SH3 domain containing 10.680
CAV1caveolin 1, caveolae protein, 22kDa0.663
NCOR1nuclear receptor corepressor 10.622
PRKG1protein kinase, cGMP-dependent, type I0.593
AGTPBP1ATP/GTP binding protein 10.590
PLXND1plexin D10.584
CBX7chromobox homolog 70.571
CDK9cyclin-dependent kinase 90.512
PCGF2polycomb group ring finger 20.509
FGF7fibroblast growth factor 70.448
FGFR3fibroblast growth factor receptor 30.435
FGF1fibroblast growth factor 1 (acidic)0.420
USP11ubiquitin specific peptidase 110.400
CPEcarboxypeptidase E0.394
PTPRCprotein tyrosine phosphatase, receptor type, C0.390
FGF10fibroblast growth factor 100.373
FGF2fibroblast growth factor 2 (basic)0.330
ACVR1activin A receptor, type I0.305
MAPK8mitogen-activated protein kinase 80.283
BMPR1Abone morphogenetic protein receptor, type IA0.269
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.266
CHD3chromodomain helicase DNA binding protein 30.261
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.257
DPP4dipeptidyl-peptidase 40.237
SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.232
TCF4transcription factor 40.224
SIN3ASIN3 homolog A, transcription regulator (yeast)0.223
CDH5cadherin 5, type 2 (vascular endothelium)0.217
NEDD4neural precursor cell expressed, developmentally down-regulated 40.212
FZD1frizzled homolog 1 (Drosophila)0.199
RDH11retinol dehydrogenase 11 (all-trans/9-cis/11-cis)0.194
LRP6low density lipoprotein receptor-related protein 60.191
FRS2fibroblast growth factor receptor substrate 20.176
SEMA6Asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.169
TGFB3transforming growth factor, beta 30.167
PCGF1polycomb group ring finger 10.162
PLXNB2plexin B20.147
CBX4chromobox homolog 40.118
PDGFCplatelet derived growth factor C0.110
STC1stanniocalcin 10.107
RUNX1T1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.106
NTRK2neurotrophic tyrosine kinase, receptor, type 20.106
MBIPMAP3K12 binding inhibitory protein 10.103
PCGF3polycomb group ring finger 30.098
ZNF512Bzinc finger protein 512B0.097
RBL1retinoblastoma-like 1 (p107)0.092
FEZ1fasciculation and elongation protein zeta 1 (zygin I)0.087
CAV2caveolin 20.085
GJA1gap junction protein, alpha 1, 43kDa0.083
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.079
DDIT4DNA-damage-inducible transcript 40.079
SLIT2slit homolog 2 (Drosophila)0.077
JAG2jagged 20.074
SHC2SHC (Src homology 2 domain containing) transforming protein 20.071
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.070
TGFBR1transforming growth factor, beta receptor 10.068
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.067
FZD8frizzled homolog 8 (Drosophila)0.064
SH3RF1SH3 domain containing ring finger 10.064
NOSTRINnitric oxide synthase trafficker0.064
PLXNB1plexin B10.063
PCDH17protocadherin 170.061
CELSR2cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)0.056
CSNK2A2casein kinase 2, alpha prime polypeptide0.054
SDC2syndecan 20.054
NOVA1neuro-oncological ventral antigen 10.053
SEMA5Asema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A0.053
TGFB2transforming growth factor, beta 20.053
PTENphosphatase and tensin homolog0.052
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.052
CTGFconnective tissue growth factor0.050
BMP4bone morphogenetic protein 40.049
DLC1deleted in liver cancer 10.049
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.049
FLRT2fibronectin leucine rich transmembrane protein 20.048
BCAMbasal cell adhesion molecule (Lutheran blood group)0.048
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.048
CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 30.047
SLC6A8solute carrier family 6 (neurotransmitter transporter, creatine), member 80.047
MYBBP1AMYB binding protein (P160) 1a0.047
UNC119unc-119 homolog (C. elegans)0.047
PTPRBprotein tyrosine phosphatase, receptor type, B0.047
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
wnt3wingless-type MMTV integration site family, member 30.718
tbx1T-box 10.667
robo3roundabout homolog 30.621
bmp2abone morphogenetic protein 2a0.590
nrp1aneuropilin 1a0.589
wnt4awingless-type MMTV integration site family, member 4a0.489
lhx2bLIM homeobox 2b0.355
sp8asp8 transcription factor a0.351
robo1roundabout homolog 10.324
dlx2adistal-less homeobox gene 2a0.276
slit3slit (Drosophila) homolog 30.231
mecomMDS1 and EVI1 complex locus0.223
fgf3fibroblast growth factor 30.206
ret1receptor tyrosine kinase0.198
otx5orthodenticle homolog 50.185
tcf7transcription factor 7 (T-cell specific, HMG-box)0.182
wnt8bwingless-type MMTV integration site family, member 8b0.172
lef1lymphocyte enhancer binding factor 10.171
itgavintegrin, alpha V0.165
wnt10awingless-type MMTV integration site family, member 10a0.150
wnt1wingless-type MMTV integration site family, member 10.149
insm1ainsulinoma-associated 1a0.124
nrp2bneuropilin 2b0.106
metmet proto-oncogene (hepatocyte growth factor receptor)0.089
fgf4fibroblast growth factor 40.088
tbx2bT-box 2b0.087
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.087
phox2apaired-like homeobox 2a0.087
wnt7aawingless-type MMTV integration site family, member 7Aa0.084
esrrgaestrogen-related receptor gamma a0.083
cntn2contactin 20.083
flot1flotillin 10.081
wnt7bawingless-type MMTV integration site family, member 7Ba0.076
osr1odd-skipped related 1 (Drosophila)0.072
plxna4plexin A40.072
wnt2wingless-type MMTV integration site family member 20.069
wnt9bwingless-type MMTV integration site family, member 9B0.069
sim1asingle-minded homolog 1a (Drosophila)0.068
lhx3LIM homeobox 30.065
zbtb4zinc finger and BTB domain containing 40.064
tbx2aT-box gene 2a0.061
dbx1adeveloping brain homeobox 1a0.060
sema3dsemaphorin 3d0.059
col11a2collagen type XI alpha-20.057
igfbp3insulin-like growth factor binding protein 30.055
irx2airoquois homeobox protein 2, a0.054
cxcr4bchemokine (C-X-C motif), receptor 4b0.054
onecutlone cut domain, family member, like0.050
sema3esema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E0.050
wnt2bbwingless-type MMTV integration site family, member 2Bb0.049
sox2SRY-box containing gene 20.049
sfrp1asecreted frizzled-related protein 1a0.047
exorhextra-ocular rhodopsin0.047
nkx3.2NK3 homeobox 20.046
shhasonic hedgehog a0.045
wnt10bwingless-type MMTV integration site family, member 10b0.044
gli1GLI-Kruppel family member 10.044
epb4.1l4erythrocyte protein band 4.1-like 40.043
slit2slit (Drosophila) homolog 20.041
sulf1sulfatase 10.041
hs3st3b1bheparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b0.041
spry4sprouty (Drosophila) homolog 40.040
pcdh18bprotocadherin 18b0.039
fgf10afibroblast growth factor 10a0.039
wlswntless homolog (Drosophila)0.039
myf5myogenic factor 50.037
eya1eyes absent homolog 10.037
robo2roundabout homolog 20.033
slit1bslit homolog 1b (Drosophila)0.032
osr2odd-skipped related 2 (Drosophila)0.031
ntn1bnetrin 1b0.031
hoxa13bhomeo box A13b0.029
fezf2FEZ family zinc finger 20.029
gbx2gastrulation brain homeo box 20.029
tal2T-cell acute lymphocytic leukemia 20.029
evx1even-skipped homeobox 10.029
wnt3awingless-type MMTV integration site family, member 3A0.028
foxa1forkhead box A10.027
slit1aslit homolog 1a (Drosophila)0.027
eng1aengrailed 1a0.027
lhx6LIM homeobox 60.026
flot2aflotillin 2a0.026
vcanbversican b0.026
dpysl2bdihydropyrimidinase-like 2b0.026
ptprfprotein tyrosine phosphatase, receptor type, F0.026
nos1nitric oxide synthase 1 (neuronal)0.026
bmp4bone morphogenetic protein 40.025
runx3runt-related transcription factor 30.025
irx1airoquois homeobox protein 1, a0.025
irx3airoquois homeobox protein 3a0.025
tnfsf10l3tumor necrosis factor (ligand) superfamily, member 10 like 30.025
amotl2aangiomotin like 2a0.024
wnt5bwingless-type MMTV integration site family, member 5b0.024
fgf17fibroblast growth factor 170.023
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
trioCG18214 gene product from transcript CG18214-RA0.999
Wnt5Wnt oncogene analog 50.993
unc-5CG8166 gene product from transcript CG8166-RA0.990
robo3CG5423 gene product from transcript CG5423-RA0.986
DscamDown syndrome cell adhesion molecule0.976
Sema-1aCG18405 gene product from transcript CG18405-RD0.969
stanstarry night0.946
Ptp69DProtein tyrosine phosphatase 69D0.917
plexBplexin B0.915
CapsCalcium activated protein for secretion0.913
emsempty spiracles0.868
Fas2Fasciclin 20.779
Sema-2aCG4700 gene product from transcript CG4700-RC0.766
CG33960CG33960 gene product from transcript CG33960-RB0.759
Hr51Hormone receptor 510.735
AblAbl tyrosine kinase0.725
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.706
gogogolden goal0.640
stumpsCG31317 gene product from transcript CG31317-RC0.575
E(spl)Enhancer of split0.571
futschCG34387 gene product from transcript CG34387-RC0.570
EphEph receptor tyrosine kinase0.538
amosabsent MD neurons and olfactory sensilla0.526
malphaE(spl) region transcript malpha0.453
HLHm7E(spl) region transcript m70.433
vndventral nervous system defective0.427
MicalMolecule interacting with CasL0.424
plexAplexin A0.402
Trim9CG31721 gene product from transcript CG31721-RB0.398
gcmglial cells missing0.333
jingCG9397 gene product from transcript CG9397-RI0.296
EphrinCG1862 gene product from transcript CG1862-RA0.259
HGTXCG13475 gene product from transcript CG13475-RB0.253
Drl-2Derailed 20.244
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.223
Sra-1specifically Rac1-associated protein 10.213
katanin-60katanin 600.213
pod1CG4532 gene product from transcript CG4532-RF0.210
vvlventral veins lacking0.209
VGlutVesicular glutamate transporter0.206
Gyc76CGuanylyl cyclase at 76C0.197
HLHmgammaE(spl) region transcript mgamma0.194
pdm3pou domain motif 30.191
nerfin-1nervous fingers 10.186
beat-Iabeaten path Ia0.179
form3formin 30.163
MrtfMyocardin-related transcription factor0.161
jebjelly belly0.160
mewmultiple edematous wings0.153
CG12424CG12424 gene product from transcript CG12424-RC0.143
Lim3CG10699 gene product from transcript CG10699-RB0.143
CG42256CG42256 gene product from transcript CG42256-RH0.139
salmspalt major0.129
Fas3Fasciclin 30.127
RhoGAP93BCG3421 gene product from transcript CG3421-RA0.113
NotumCG13076 gene product from transcript CG13076-RB0.111
neuroliginCG13772 gene product from transcript CG13772-RA0.092
Fak56DFocal Adhesion Kinase0.091
DAAMDishevelled Associated Activator of Morphogenesis0.087
wbwing blister0.084
HLHm5E(spl) region transcript m50.083
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Nfibnuclear factor I/B0.031
Grip1glutamate receptor interacting protein 10.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism