The network for 'negative regulation of smooth muscle cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of smooth muscle cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.

NameDescriptionProbabilityFunc Analog Organism
CREBBPCREB binding protein0.820
ARandrogen receptor0.235
NCOA1nuclear receptor coactivator 10.101
NCOA2nuclear receptor coactivator 20.090
FOXO3forkhead box O30.086
FOXO1forkhead box O10.050
NCOA6nuclear receptor coactivator 60.049
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.030
FHL2four and a half LIM domains 20.023
CREB1cAMP responsive element binding protein 10.018
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.014
APCadenomatous polyposis coli0.013
LDLRlow density lipoprotein receptor0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gli3GLI-Kruppel family member GLI30.950
Fgfr2fibroblast growth factor receptor 20.883
Pthlhparathyroid hormone-like peptide0.187
Sox9SRY-box containing gene 90.183
Col2a1collagen, type II, alpha 10.119
Pax2paired box gene 20.108
Bmp4bone morphogenetic protein 40.083
Fgfr3fibroblast growth factor receptor 30.066
Ctnnb1catenin (cadherin associated protein), beta 10.060
Ror2receptor tyrosine kinase-like orphan receptor 20.049
Pitx2paired-like homeodomain transcription factor 20.048
Msx1homeobox, msh-like 10.047
Foxc1forkhead box C10.045
Pax3paired box gene 30.039
Gli2GLI-Kruppel family member GLI20.035
Otx2orthodenticle homolog 2 (Drosophila)0.031
Ptenphosphatase and tensin homolog0.028
Fgf8fibroblast growth factor 80.026
Arandrogen receptor0.025
Bmp7bone morphogenetic protein 70.023
Invsinversin0.022
Gata4GATA binding protein 40.021
Fgf10fibroblast growth factor 100.019
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.018
Nr5a1nuclear receptor subfamily 5, group A, member 10.016
Hand1heart and neural crest derivatives expressed transcript 10.016
Smpd3sphingomyelin phosphodiesterase 3, neutral0.016
Tcf21transcription factor 210.015
Fgf9fibroblast growth factor 90.014
Tcfap2atranscription factor AP-2, alpha0.014
Vangl2vang-like 2 (van gogh, Drosophila)0.014
Runx2runt related transcription factor 20.013
P2rx1purinergic receptor P2X, ligand-gated ion channel, 10.013
Pitx1paired-like homeodomain transcription factor 10.013
Cdoncell adhesion molecule-related/down-regulated by oncogenes0.012
Tbx3T-box 30.012
Rxraretinoid X receptor alpha0.012
Psg17pregnancy specific glycoprotein 170.011
Zeb1zinc finger E-box binding homeobox 10.011
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.011
Med30mediator complex subunit 300.011
Emx2empty spiracles homolog 2 (Drosophila)0.011
Nr0b1nuclear receptor subfamily 0, group B, member 10.010
Spry4sprouty homolog 4 (Drosophila)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism