The network for 'serotonin transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

serotonin transport

The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.

NameDescriptionProbabilityFunc Analog Organism
PTPN6protein tyrosine phosphatase, non-receptor type 60.999
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.997
UBASH3Bubiquitin associated and SH3 domain containing B0.992
PILRApaired immunoglobin-like type 2 receptor alpha0.986
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.984
PICK1protein interacting with PRKCA 10.959
SIGLEC7sialic acid binding Ig-like lectin 70.892
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.847
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.790
CRHR1corticotropin releasing hormone receptor 10.788
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.751
VAC14Vac14 homolog (S. cerevisiae)0.614
FADS2fatty acid desaturase 20.579
DHCR77-dehydrocholesterol reductase0.557
PTAFRplatelet-activating factor receptor0.547
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.526
BLNKB-cell linker0.512
CD33CD33 molecule0.494
DRD2dopamine receptor D20.486
SH3BP2SH3-domain binding protein 20.473
LCKlymphocyte-specific protein tyrosine kinase0.416
SIRPB1signal-regulatory protein beta 10.414
TPPPtubulin polymerization promoting protein0.333
TYMPthymidine phosphorylase0.306
MAPTmicrotubule-associated protein tau0.270
APLP1amyloid beta (A4) precursor-like protein 10.267
CCR1chemokine (C-C motif) receptor 10.238
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.232
BTKBruton agammaglobulinemia tyrosine kinase0.166
SNCAIPsynuclein, alpha interacting protein0.147
FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32)0.143
FCGR2CFc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)0.138
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.137
DLG4discs, large homolog 4 (Drosophila)0.127
TYROBPTYRO protein tyrosine kinase binding protein0.127
FCGR3BFc fragment of IgG, low affinity IIIb, receptor (CD16b)0.124
CD86CD86 molecule0.120
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.118
DOCK7dedicator of cytokinesis 70.112
GRB7growth factor receptor-bound protein 70.099
HK3hexokinase 3 (white cell)0.098
EPORerythropoietin receptor0.096
SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.092
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.090
TREM1triggering receptor expressed on myeloid cells 10.089
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.088
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.088
AOAHacyloxyacyl hydrolase (neutrophil)0.082
CYBBcytochrome b-245, beta polypeptide0.080
FCN1ficolin (collagen/fibrinogen domain containing) 10.079
PRLHRprolactin releasing hormone receptor0.076
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.071
LILRA3leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 30.071
NOD2nucleotide-binding oligomerization domain containing 20.071
SLASrc-like-adaptor0.069
SYN1synapsin I0.066
SYKspleen tyrosine kinase0.064
CD163CD163 molecule0.064
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.063
IGSF6immunoglobulin superfamily, member 60.061
PRKCGprotein kinase C, gamma0.060
NLRP3NLR family, pyrin domain containing 30.059
VNN2vanin 20.057
NOS1APnitric oxide synthase 1 (neuronal) adaptor protein0.055
SLC15A3solute carrier family 15, member 30.053
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)0.051
FPR2formyl peptide receptor 20.051
PLEKpleckstrin0.051
C3AR1complement component 3a receptor 10.050
VSIG4V-set and immunoglobulin domain containing 40.050
TLR8toll-like receptor 80.048
CD300CCD300c molecule0.047
AQP9aquaporin 90.045
RHOrhodopsin0.044
STX1Asyntaxin 1A (brain)0.042
LILRB4leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 40.042
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 20.042
PDE4DIPphosphodiesterase 4D interacting protein0.042
HTR1D5-hydroxytryptamine (serotonin) receptor 1D0.041
PIK3R5phosphoinositide-3-kinase, regulatory subunit 50.040
MARCOmacrophage receptor with collagenous structure0.040
SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin0.040
SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 30.040
TUBtubby homolog (mouse)0.040
CD22CD22 molecule0.039
BEST1bestrophin 10.037
SIX6SIX homeobox 60.036
CEACAM3carcinoembryonic antigen-related cell adhesion molecule 30.035
KCNQ2potassium voltage-gated channel, KQT-like subfamily, member 20.035
AIF1allograft inflammatory factor 10.034
CASP5caspase 5, apoptosis-related cysteine peptidase0.033
CHRNA4cholinergic receptor, nicotinic, alpha 40.033
RASSF4Ras association (RalGDS/AF-6) domain family member 40.032
MS4A4Amembrane-spanning 4-domains, subfamily A, member 40.032
HERPUD1homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 10.032
MAGmyelin associated glycoprotein0.032
HNF4Ahepatocyte nuclear factor 4, alpha0.031
BMP8Abone morphogenetic protein 8a0.031
CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.031
FEZF2FEZ family zinc finger 20.031
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sncgbsynuclein, gamma b (breast cancer-specific protein 1)0.051
htr1aa5-hydroxytryptamine (serotonin) receptor 1A a0.047
ddcdopa decarboxylase0.034
lpar1lysophosphatidic acid receptor 10.020
nlgn4bneuroligin 4b0.019
gperG protein-coupled estrogen receptor 10.016
dpysl5bdihydropyrimidinase-like 5b0.014
prom1aprominin 1a0.014
htr1bd5-hydroxytryptamine (serotonin) receptor 1bd0.013
cyp4t8cytochrome P450, family 4, subfamily T, polypeptide 80.012
fevFEV (ETS oncogene family)0.012
hcrtr2hypocretin (orexin) receptor 20.012
crhbpcorticotropin releasing hormone binding protein0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Drd2dopamine receptor D20.971
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.965
Ppargperoxisome proliferator activated receptor gamma0.913
Mbmyoglobin0.705
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.524
Pnpla2patatin-like phospholipase domain containing 20.509
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.376
Klklotho0.376
Emx1empty spiracles homolog 1 (Drosophila)0.357
Nos1nitric oxide synthase 1, neuronal0.356
Adrb1adrenergic receptor, beta 10.332
Esr1estrogen receptor 1 (alpha)0.255
Hcsthematopoietic cell signal transducer0.243
Cd247CD247 antigen0.213
Tbxas1thromboxane A synthase 1, platelet0.213
Apoeapolipoprotein E0.212
MefvMediterranean fever0.210
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.193
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.131
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.129
Kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.128
Nfam1Nfat activating molecule with ITAM motif 10.128
Lepleptin0.127
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.125
Adrb3adrenergic receptor, beta 30.119
Npy2rneuropeptide Y receptor Y20.115
Trpv1transient receptor potential cation channel, subfamily V, member 10.104
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.095
Trem3triggering receptor expressed on myeloid cells 30.092
TyrobpTYRO protein tyrosine kinase binding protein0.091
Sox10SRY-box containing gene 100.090
ND6NADH dehydrogenase subunit 60.084
Leprleptin receptor0.082
Lair1leukocyte-associated Ig-like receptor 10.081
Clec4nC-type lectin domain family 4, member n0.080
Nr3c1nuclear receptor subfamily 3, group C, member 10.079
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.078
Mogmyelin oligodendrocyte glycoprotein0.076
Hrh1histamine receptor H10.075
Msr1macrophage scavenger receptor 10.069
Siglec1sialic acid binding Ig-like lectin 1, sialoadhesin0.069
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.066
Marcomacrophage receptor with collagenous structure0.062
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.060
Syt6synaptotagmin VI0.058
Cd300lbCD300 antigen like family member B0.058
Il4interleukin 40.057
Npy1rneuropeptide Y receptor Y10.054
Chrm1cholinergic receptor, muscarinic 1, CNS0.051
Adora2aadenosine A2a receptor0.051
Lhx6LIM homeobox protein 60.051
Slc22a12solute carrier family 22 (organic anion/cation transporter), member 120.051
Drd1adopamine receptor D1A0.050
Ptgs2prostaglandin-endoperoxide synthase 20.050
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.048
Cnr1cannabinoid receptor 1 (brain)0.048
Cacng5calcium channel, voltage-dependent, gamma subunit 50.047
Gabrdgamma-aminobutyric acid (GABA) A receptor, subunit delta0.047
Tectbtectorin beta0.047
Nos2nitric oxide synthase 2, inducible0.047
Pcsk2proprotein convertase subtilisin/kexin type 20.046
Cfhcomplement component factor h0.045
Shc3src homology 2 domain-containing transforming protein C30.045
Grid1glutamate receptor, ionotropic, delta 10.040
F7coagulation factor VII0.040
Cx3cr1chemokine (C-X3-C) receptor 10.040
Tbpl2TATA box binding protein like 20.040
Kitkit oncogene0.040
Siglecesialic acid binding Ig-like lectin E0.039
Htr45 hydroxytryptamine (serotonin) receptor 40.039
Folr2folate receptor 2 (fetal)0.039
Htr5a5-hydroxytryptamine (serotonin) receptor 5A0.039
Sstr1somatostatin receptor 10.038
P2rx7purinergic receptor P2X, ligand-gated ion channel, 70.037
Unc79unc-79 homolog (C. elegans)0.036
Plauplasminogen activator, urokinase0.036
Sstr4somatostatin receptor 40.035
Adrb2adrenergic receptor, beta 20.035
Ucp1uncoupling protein 1 (mitochondrial, proton carrier)0.034
Rab3il1RAB3A interacting protein (rabin3)-like 10.034
Pick1protein interacting with C kinase 10.034
Epha6Eph receptor A60.034
Gp5glycoprotein 5 (platelet)0.034
Gsx1GS homeobox 10.033
AF251705cDNA sequence AF2517050.032
Cd33CD33 antigen0.032
Gpr37l1G protein-coupled receptor 37-like 10.032
Hrkharakiri, BCL2 interacting protein (contains only BH3 domain)0.031
Grm2glutamate receptor, metabotropic 20.030
2210010C04RikRIKEN cDNA 2210010C04 gene0.030
Glra1glycine receptor, alpha 1 subunit0.030
Sstr3somatostatin receptor 30.030
Crhr1corticotropin releasing hormone receptor 10.029
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.029
Col4a3collagen, type IV, alpha 30.029
Syn2synapsin II0.029
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.029
Gabra2gamma-aminobutyric acid (GABA) A receptor, subunit alpha 20.028
SeboxSEBOX homeobox0.028
Galr1galanin receptor 10.027
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Htr5a5-hydroxytryptamine (serotonin) receptor 5A0.045
FevFEV (ETS oncogene family)0.040
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.036
Dock8dedicator of cytokinesis 80.035
Scn10asodium channel, voltage-gated, type X, alpha subunit0.029
Naaladl1N-acetylated alpha-linked acidic dipeptidase-like 10.025
Gzmkgranzyme K0.025
Hrh3histamine receptor H30.024
Vipr2vasoactive intestinal peptide receptor 20.023
Slc14a2solute carrier family 14 (urea transporter), member 20.022
Thtyrosine hydroxylase0.021
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 10.020
Gpr1G protein-coupled receptor 10.019
Slc22a7solute carrier family 22 (organic anion transporter), member 70.018
Ucnurocortin0.018
Dccdeleted in colorectal carcinoma0.017
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.015
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.015
Bcl2l10BCL2-like 10 (apoptosis facilitator)0.015
Megf6multiple EGF-like-domains 60.014
Grin2cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.014
Ptprz1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.014
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.013
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.013
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.012
Onecut1one cut homeobox 10.012
Ncanneurocan0.012
Pitx3paired-like homeodomain 30.012
Lepleptin0.012
Notch3Notch homolog 3 (Drosophila)0.012
Chrm2cholinergic receptor, muscarinic 20.012
Grk4G protein-coupled receptor kinase 40.012
SagS-antigen; retina and pineal gland (arrestin)0.011
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.011
Gfra2GDNF family receptor alpha 20.011
Hand1heart and neural crest derivatives expressed 10.011
Folh1folate hydrolase 10.010
Chrna7cholinergic receptor, nicotinic, alpha 70.010
Chrnecholinergic receptor, nicotinic, epsilon0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism