The network for 'cell projection organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell projection organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.

NameDescriptionProbabilityFunc Analog Organism
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
FYNFYN oncogene related to SRC, FGR, YES1.000
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.999
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.998
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.998
GRB2growth factor receptor-bound protein 20.998
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.998
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.998
EGFRepidermal growth factor receptor0.997
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.994
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.990
CREBBPCREB binding protein0.989
ATXN1ataxin 10.988
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.988
BCAR1breast cancer anti-estrogen resistance 10.982
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.981
RHOAras homolog gene family, member A0.980
FLNAfilamin A, alpha0.978
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.973
FN1fibronectin 10.970
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.952
LCKlymphocyte-specific protein tyrosine kinase0.942
SHC1SHC (Src homology 2 domain containing) transforming protein 10.940
MOBKL3MOB1, Mps One Binder kinase activator-like 3 (yeast)0.937
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.936
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.935
ACTBactin, beta0.932
PXNpaxillin0.927
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.925
QKIquaking homolog, KH domain RNA binding (mouse)0.919
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.911
GAS7growth arrest-specific 70.911
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.903
MSNmoesin0.896
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.893
SMAD2SMAD family member 20.886
ATN1atrophin 10.878
MAPTmicrotubule-associated protein tau0.874
PLCG1phospholipase C, gamma 10.870
AKT1v-akt murine thymoma viral oncogene homolog 10.863
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.856
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.853
LMNAlamin A/C0.844
PPP1R12Aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.840
NCOR1nuclear receptor corepressor 10.830
ARandrogen receptor0.828
ILKintegrin-linked kinase0.821
SYKspleen tyrosine kinase0.815
CFL1cofilin 1 (non-muscle)0.814
FGFR1fibroblast growth factor receptor 10.804
APPamyloid beta (A4) precursor protein0.798
METmet proto-oncogene (hepatocyte growth factor receptor)0.797
MAP3K5mitogen-activated protein kinase kinase kinase 50.797
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.790
RAB1ARAB1A, member RAS oncogene family0.788
ZYXzyxin0.780
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.755
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.735
CALM1calmodulin 1 (phosphorylase kinase, delta)0.720
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.720
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.717
ABI1abl-interactor 10.701
SMAD1SMAD family member 10.695
SFNstratifin0.690
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.687
ITSN1intersectin 1 (SH3 domain protein)0.686
RBBP4retinoblastoma binding protein 40.673
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.667
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.663
MAPK8mitogen-activated protein kinase 80.662
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.638
RB1retinoblastoma 10.634
MPDZmultiple PDZ domain protein0.631
NTRK3neurotrophic tyrosine kinase, receptor, type 30.625
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.623
TP53tumor protein p530.620
SMURF2SMAD specific E3 ubiquitin protein ligase 20.617
PTPN1protein tyrosine phosphatase, non-receptor type 10.617
ATRXalpha thalassemia/mental retardation syndrome X-linked0.612
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.611
GRB7growth factor receptor-bound protein 70.608
JUNjun proto-oncogene0.602
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.598
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.590
MPRIPmyosin phosphatase Rho interacting protein0.587
JAG1jagged 10.587
RAB5ARAB5A, member RAS oncogene family0.581
PRKCZprotein kinase C, zeta0.578
ARRB1arrestin, beta 10.578
SOS1son of sevenless homolog 1 (Drosophila)0.577
PKM2pyruvate kinase, muscle0.560
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.560
HSPG2heparan sulfate proteoglycan 20.555
SMAD3SMAD family member 30.554
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.550
NCK1NCK adaptor protein 10.547
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.525
PTK2PTK2 protein tyrosine kinase 20.524
WDYHV1WDYHV motif containing 10.519
ROCK1Rho-associated, coiled-coil containing protein kinase 10.519
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.999
hlh-2Protein HLH-20.983
pha-4Protein PHA-40.979
osm-5Protein OSM-50.971
pry-1Protein PRY-10.941
unc-73Protein UNC-730.932
osm-3Protein OSM-30.927
unc-53Protein UNC-530.893
act-4Protein ACT-40.891
elt-6Protein ELT-60.890
nhr-67Protein NHR-670.873
unc-52Protein UNC-520.871
osm-6Protein OSM-60.868
atn-1Protein ATN-10.859
ida-1Protein IDA-10.847
flt-1Protein FLT-10.846
che-13Protein CHE-130.841
egl-46Protein EGL-460.826
hbl-1Protein HBL-10.805
let-60Protein LET-600.796
T27A3.1Protein T27A3.10.794
bar-1Protein BAR-10.779
unc-104Protein UNC-1040.764
sem-5Protein SEM-50.756
fkh-2Protein FKH-20.754
sli-1Protein SLI-10.747
sel-12Protein SEL-120.738
vab-3Protein VAB-30.736
cye-1Protein CYE-10.736
hmp-1Protein HMP-10.727
che-2Protein CHE-20.727
daf-11Protein DAF-110.725
hnd-1Protein HND-10.724
egl-13Protein EGL-130.720
hlh-1Protein HLH-10.712
unc-42Protein UNC-420.676
cam-1Protein CAM-10.673
ain-1Protein AIN-10.612
mig-5Protein MIG-50.606
ten-1Protein TEN-10.600
lin-29Protein LIN-290.597
jbts-14Protein JBTS-140.581
ldb-1Protein LDB-10.578
unc-9Protein UNC-90.574
syg-1Protein SYG-10.574
pop-1Protein POP-10.569
egl-8Protein EGL-80.549
mpk-1Protein MPK-10.547
mec-8Protein MEC-80.544
eor-1Protein EOR-10.540
pat-3Protein PAT-30.528
T28F4.1Protein T28F4.10.523
nphp-4Protein NPHP-40.523
sax-3Protein SAX-30.515
cnd-1Protein CND-10.507
aspm-1Protein ASPM-10.506
egl-15Protein EGL-150.501
lsy-2Protein LSY-20.498
glp-1Protein GLP-10.496
T21B6.3Protein T21B6.30.491
tbc-2Protein TBC-20.490
mep-1Protein MEP-10.483
hcp-3Protein HCP-30.481
mef-2Protein MEF-20.472
K10D6.4Protein K10D6.40.469
teg-4Protein TEG-40.462
sma-6Protein SMA-60.450
pxf-1Protein PXF-10.449
CELE_F59A6.5Protein F59A6.50.448
C11E4.6Protein C11E4.60.447
unc-62Protein UNC-620.441
eps-8Protein EPS-80.431
unc-98Protein UNC-980.427
etr-1Protein ETR-10.427
srgp-1Protein SRGP-10.423
egl-5Protein EGL-50.418
ncl-1Protein NCL-10.417
goa-1Protein GOA-10.414
fem-2Protein FEM-20.410
gon-4Protein GON-40.403
tni-3Protein TNI-30.400
nphp-1Protein NPHP-10.398
daf-3Protein DAF-30.397
soc-2Protein SOC-20.396
egl-27Protein EGL-270.386
daf-19Protein DAF-190.381
arx-2Protein ARX-20.381
osm-12Protein OSM-120.381
elpc-4Protein ELPC-40.379
rnr-1Protein RNR-10.372
lag-1Protein LAG-10.371
odr-3Protein ODR-30.369
M01A10.1Protein M01A10.10.362
mom-2Protein MOM-20.362
sur-2Protein SUR-20.361
tbx-9Protein TBX-90.360
Y44E3A.6Protein Y44E3A.60.357
ceh-13Protein CEH-130.356
ztf-19Protein ZTF-190.353
age-1Protein AGE-10.348
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
gli1GLI-Kruppel family member 10.997
ift88intraflagellar transport 88 homolog0.996
shhasonic hedgehog a0.994
lamc1laminin, gamma 10.992
pax2apaired box gene 2a0.991
flhfloating head0.978
arl13bADP-ribosylation factor-like 13b0.977
lamb1alaminin, beta 1a0.972
ttnatitin a0.967
lrrc6leucine rich repeat containing 60.965
pitx3paired-like homeodomain transcription factor 30.964
dag1dystroglycan 10.961
cdh2cadherin 2, neuronal0.951
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.948
pkd2polycystic kidney disease 20.943
gdf6agrowth differentiation factor 6a0.934
fgf3fibroblast growth factor 30.932
bmp4bone morphogenetic protein 40.932
dmddystrophin0.928
olig2oligodendrocyte lineage transcription factor 20.926
notch1anotch homolog 1a0.923
myhz2myosin, heavy polypeptide 2, fast muscle specific0.919
cxcr4bchemokine (C-X-C motif), receptor 4b0.919
dccdeleted in colorectal carcinoma0.913
chdchordin0.913
epb41l5erythrocyte membrane protein band 4.1 like 50.901
gsnagelsolin a0.896
robo2roundabout homolog 20.877
ptpraprotein tyrosine phosphatase, receptor type, A0.876
oepone-eyed pinhead0.873
nesnestin0.871
gata2aGATA-binding protein 2a0.871
flot1bflotillin 1b0.870
dladeltaA0.868
fgf8afibroblast growth factor 8 a0.864
tjp1tight junction protein 1 (zona occludens 1)0.862
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.855
spry4sprouty (Drosophila) homolog 40.854
aldh1a2aldehyde dehydrogenase 1 family, member A20.847
ift57intraflagellar transport protein 570.846
sox1aSRY-box containing gene 1a0.836
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.830
hnf1baHNF1 homeobox Ba0.812
wnt11wingless-type MMTV integration site family, member 110.811
disp1dispatched homolog 1 (Drosophila)0.811
fstl1bfollistatin-like 1b0.807
per3period homolog 3 (Drosophila)0.807
mbpmyelin basic protein0.805
wnt4awingless-type MMTV integration site family, member 4a0.803
foxn4forkhead box N40.802
cc2d2acoiled-coil and C2 domain containing 2A0.801
neurodneurogenic differentiation0.800
camk2g1calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 10.799
nkx2.2aNK2 transcription factor related 2a0.795
evx1even-skipped homeobox 10.795
ptch2patched 20.794
olfm2olfactomedin 20.791
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.789
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.783
lhx1aLIM homeobox 1a0.781
atoh1batonal homolog 1b0.777
sema3absemaphorin 3ab0.775
pink1PTEN induced putative kinase 10.774
fgfr1afibroblast growth factor receptor 1a0.773
unc45bunc-45 homolog B (C. elegans)0.773
tpbgltrophoblast glycoprotein-like0.765
frem3Fras1 related extracellular matrix 30.763
gyltl1bglycosyltransferase-like 1b0.759
wnt2bbwingless-type MMTV integration site family, member 2Bb0.758
jag2jagged 20.758
lrrc50leucine rich repeat containing 500.758
fezf2FEZ family zinc finger 20.757
wnt10awingless-type MMTV integration site family, member 10a0.756
pax7apaired box gene 7a0.755
actn2actinin, alpha 20.754
mfn2mitofusin 20.750
sept6septin 60.749
hspg2heparan sulfate proteoglycan 20.746
mmp9matrix metalloproteinase 90.745
sim1asingle-minded homolog 1a (Drosophila)0.744
notch2notch homolog 20.742
ncam1bneural cell adhesion molecule 1b0.730
atoh1aatonal homolog 1a0.728
emx3empty spiracles homeobox 30.728
rfx2regulatory factor X, 2 (influences HLA class II expression)0.727
lama5laminin, alpha 50.723
dpysl3dihydropyrimidinase-like 30.722
inabinternexin neuronal intermediate filament protein, alpha b0.720
pcdh10aprotocadherin 10a0.710
fgf10afibroblast growth factor 10a0.706
nr2e1nuclear receptor subfamily 2, group E, member 10.704
wnt1wingless-type MMTV integration site family, member 10.702
gpr98G protein-coupled receptor 980.700
foxa2forkhead box A20.699
actn1actinin, alpha 10.695
dlbdeltaB0.694
esrrgaestrogen-related receptor gamma a0.690
ptf1apancreas specific transcription factor, 1a0.690
nxph1neurexophilin 10.687
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.681
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.968
Lin7blin-7 homolog b (C. elegans)0.866
Map2microtubule-associated protein 20.668
Actbactin, beta0.658
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.613
Nrxn1neurexin 10.601
Pls3plastin 3 (T-isoform)0.593
Ccl2chemokine (C-C motif) ligand 20.579
Gria2glutamate receptor, ionotropic, AMPA 20.569
Cttncortactin0.551
Strnstriatin, calmodulin binding protein0.550
Dlgap1discs, large (Drosophila) homolog-associated protein 10.549
Plauplasminogen activator, urokinase0.549
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.547
Dlgap3discs, large (Drosophila) homolog-associated protein 30.545
Accn1amiloride-sensitive cation channel 1, neuronal0.522
Nrxn3neurexin 30.516
Pfn1profilin 10.510
Grip1glutamate receptor interacting protein 10.506
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.494
FynFYN oncogene related to SRC, FGR, YES0.487
Map1bmicrotubule-associated protein 1B0.485
Bcl2B-cell CLL/lymphoma 20.483
Prkcaprotein kinase C, alpha0.477
Map6microtubule-associated protein 60.475
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.467
Myo1cmyosin IC0.460
Anxa2annexin A20.452
Nedd4neural precursor cell expressed, developmentally down-regulated 40.450
Jak1Janus kinase 10.433
Cd9CD9 molecule0.430
Rap1bRAP1B, member of RAS oncogene family0.424
Appamyloid beta (A4) precursor protein0.420
Drd2dopamine receptor D20.417
Dchs1dachsous 1 (Drosophila)0.416
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.415
Dlg4discs, large homolog 4 (Drosophila)0.413
Sp4Sp4 transcription factor0.408
Cyth3cytohesin 30.396
Ncam1neural cell adhesion molecule 10.394
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.394
Sirpasignal-regulatory protein alpha0.390
C1rcomplement component 1, r subcomponent0.387
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.381
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.379
Syt4synaptotagmin IV0.372
Brunol4bruno-like 4, RNA binding protein (Drosophila)0.372
Tmod2tropomodulin 20.370
Ednrbendothelin receptor type B0.360
Gnalguanine nucleotide binding protein, alpha stimulating, olfactory type0.359
Ctnnd2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)0.355
Sncbsynuclein, beta0.354
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.352
Metmet proto-oncogene0.351
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.350
Syt17synaptotagmin XVII0.348
Pde4bphosphodiesterase 4B, cAMP specific0.347
Lamc1laminin, gamma 10.345
Sdc3syndecan 30.345
Nr4a2nuclear receptor subfamily 4, group A, member 20.340
Itgb1integrin, beta 10.340
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.338
Utrnutrophin0.338
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.336
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.334
Sc65synaptonemal complex protein SC650.333
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.332
Vcanversican0.331
Acvr1activin A receptor, type I0.328
Hckhemopoietic cell kinase0.318
Tacr3tachykinin receptor 30.318
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.318
Stx1bsyntaxin 1B0.316
Ppp2r2cprotein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform0.312
Galr3galanin receptor 30.312
Tpm3tropomyosin 3, gamma0.311
Cd44Cd44 molecule0.311
Slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 10.310
Gria3glutamate receptor, ionotrophic, AMPA 30.308
Picalmphosphatidylinositol binding clathrin assembly protein0.305
Spire1spire homolog 1 (Drosophila)0.302
Adam17ADAM metallopeptidase domain 170.299
Socs3suppressor of cytokine signaling 30.297
Nfibnuclear factor I/B0.295
Adrb1adrenergic, beta-1-, receptor0.294
Gdf11growth differentiation factor 110.294
Agtr2angiotensin II receptor, type 20.291
Cadm1cell adhesion molecule 10.287
Cltcclathrin, heavy chain (Hc)0.285
Stat6signal transducer and activator of transcription 60.284
Fgfr1Fibroblast growth factor receptor 10.283
Hoxa2homeo box A20.280
Bdkrb2bradykinin receptor B20.279
Samd14sterile alpha motif domain containing 140.278
Lnpepleucyl/cystinyl aminopeptidase0.277
Sptan1spectrin, alpha, non-erythrocytic 10.277
Iqgap1IQ motif containing GTPase activating protein 10.274
Scn3asodium channel, voltage-gated, type III, alpha0.274
Slc6a1solute carrier family 6 (neurotransmitter transporter, GABA), member 10.271
Ngfnerve growth factor (beta polypeptide)0.271
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism