The network for 'interleukin 1 beta biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

interleukin 1 beta biosynthetic process

The chemical reactions and pathways resulting in the formation of interleukin-1 beta.

NameDescriptionProbabilityFunc Analog Organism
GNLYgranulysin0.994
PRF1perforin 1 (pore forming protein)0.988
GZMBgranzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)0.945
NKG7natural killer cell group 7 sequence0.776
GZMKgranzyme K (granzyme 3; tryptase II)0.626
ELANEelastase, neutrophil expressed0.626
KLRD1killer cell lectin-like receptor subfamily D, member 10.539
CST7cystatin F (leukocystatin)0.396
IL2RBinterleukin 2 receptor, beta0.376
KLRK1killer cell lectin-like receptor subfamily K, member 10.362
CD8ACD8a molecule0.338
CTSGcathepsin G0.320
GPR171G protein-coupled receptor 1710.234
MPOmyeloperoxidase0.223
CXCR6chemokine (C-X-C motif) receptor 60.212
CD3DCD3d molecule, delta (CD3-TCR complex)0.201
ITKIL2-inducible T-cell kinase0.191
IL18RAPinterleukin 18 receptor accessory protein0.190
CAMPcathelicidin antimicrobial peptide0.176
SRGNserglycin0.134
TARPTCR gamma alternate reading frame protein0.126
KLRB1killer cell lectin-like receptor subfamily B, member 10.125
CD2CD2 molecule0.107
FASLGFas ligand (TNF superfamily, member 6)0.087
GZMMgranzyme M (lymphocyte met-ase 1)0.080
GZMHgranzyme H (cathepsin G-like 2, protein h-CCPX)0.076
AZU1azurocidin 10.073
PRTN3proteinase 30.063
SH2D1ASH2 domain containing 1A0.062
CTSWcathepsin W0.061
IFNGinterferon, gamma0.058
HDChistidine decarboxylase0.058
KLRG1killer cell lectin-like receptor subfamily G, member 10.048
CLEC4GC-type lectin domain family 4, member G0.046
TRAT1T cell receptor associated transmembrane adaptor 10.046
CD3GCD3g molecule, gamma (CD3-TCR complex)0.031
RNASE3ribonuclease, RNase A family, 30.030
IGL@immunoglobulin lambda locus0.026
GFI1growth factor independent 1 transcription repressor0.026
SLAMF7SLAM family member 70.025
KLRF1killer cell lectin-like receptor subfamily F, member 10.025
CD160CD160 molecule0.022
BPIbactericidal/permeability-increasing protein0.022
CCL5chemokine (C-C motif) ligand 50.021
CCL4chemokine (C-C motif) ligand 40.020
XCL2chemokine (C motif) ligand 20.020
CLEC3BC-type lectin domain family 3, member B0.020
CD96CD96 molecule0.020
TPSB2tryptase beta 2 (gene/pseudogene)0.019
CPA3carboxypeptidase A3 (mast cell)0.019
PGLYRP1peptidoglycan recognition protein 10.018
GZMAgranzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)0.018
PRG2proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)0.016
CD7CD7 molecule0.016
LAG3lymphocyte-activation gene 30.015
CFPcomplement factor properdin0.015
DEFA4defensin, alpha 4, corticostatin0.015
CD247CD247 molecule0.015
MYL4myosin, light chain 4, alkali; atrial, embryonic0.015
S100A12S100 calcium binding protein A120.014
CLEC10AC-type lectin domain family 10, member A0.014
CXCR3chemokine (C-X-C motif) receptor 30.014
F13A1coagulation factor XIII, A1 polypeptide0.013
LAIR2leukocyte-associated immunoglobulin-like receptor 20.013
LTFlactotransferrin0.013
TBX21T-box 210.012
LTC4Sleukotriene C4 synthase0.012
NFE2nuclear factor (erythroid-derived 2), 45kDa0.012
CD48CD48 molecule0.011
CD52CD52 molecule0.011
IGJimmunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides0.011
ASGR2asialoglycoprotein receptor 20.011
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism